MIR301B (microRNA mir-301b) - Rat Genome Database

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Gene: MIR301B (microRNA mir-301b) Canis lupus familiaris
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Symbol: MIR301B
Name: microRNA mir-301b
RGD ID: 12183722
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Previously known as: cfa-mir-301b; microRNA 301b
RGD Orthologs
Human
Mouse
Rat
Pig
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12630,924,103 - 30,924,178 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2630,924,103 - 30,924,178 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2630,881,301 - 30,881,376 (+)NCBI
ROS_Cfam_1.02632,329,837 - 32,329,912 (+)NCBI
UMICH_Zoey_3.12630,379,140 - 30,379,215 (+)NCBI
UNSW_CanFamBas_1.02630,002,840 - 30,002,915 (+)NCBI
UU_Cfam_GSD_1.02631,092,810 - 31,092,885 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:16381832   PMID:18215311  


Genomics

Comparative Map Data
MIR301B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12630,924,103 - 30,924,178 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2630,924,103 - 30,924,178 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2630,881,301 - 30,881,376 (+)NCBI
ROS_Cfam_1.02632,329,837 - 32,329,912 (+)NCBI
UMICH_Zoey_3.12630,379,140 - 30,379,215 (+)NCBI
UNSW_CanFamBas_1.02630,002,840 - 30,002,915 (+)NCBI
UU_Cfam_GSD_1.02631,092,810 - 31,092,885 (+)NCBI
MIR301B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382221,652,981 - 21,653,058 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2221,652,981 - 21,653,058 (+)EnsemblGRCh38hg38GRCh38
GRCh372222,007,270 - 22,007,347 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362220,337,269 - 20,337,346 (+)NCBINCBI36hg18NCBI36
Celera225,824,810 - 5,824,887 (+)NCBI
Cytogenetic Map22q11.21NCBI
HuRef224,965,094 - 4,965,171 (+)NCBIHuRef
CHM1_12222,007,462 - 22,007,539 (+)NCBICHM1_1
T2T-CHM13v2.02222,066,472 - 22,066,549 (+)NCBI
Mir301b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391616,942,264 - 16,942,360 (-)NCBIGRCm39mm39
GRCm39 Ensembl1616,942,264 - 16,942,360 (-)Ensembl
GRCm381617,124,400 - 17,124,496 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1617,124,400 - 17,124,496 (-)EnsemblGRCm38mm10GRCm38
MGSCv371617,124,493 - 17,124,589 (-)NCBIGRCm37mm9NCBIm37
Celera1617,697,194 - 17,697,290 (-)NCBICelera
Cytogenetic Map16A3NCBI
Mir301b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21183,879,816 - 83,879,893 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1183,879,816 - 83,879,893 (+)Ensembl
Rnor_6.01188,129,426 - 88,129,503 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1188,129,426 - 88,129,503 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01191,181,973 - 91,182,050 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1182,635,547 - 82,635,624 (+)NCBICelera
Cytogenetic Map11q23NCBI
MIR130B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1450,245,041 - 50,245,120 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11450,245,041 - 50,245,120 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21453,695,562 - 53,695,641 (-)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

reproductive system
High
Medium
Low
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000039952
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2630,924,103 - 30,924,178 (+)Ensembl
RefSeq Acc Id: NR_049442
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12630,924,103 - 30,924,178 (+)NCBI
Dog10K_Boxer_Tasha2630,881,301 - 30,881,376 (+)NCBI
ROS_Cfam_1.02632,329,837 - 32,329,912 (+)NCBI
UMICH_Zoey_3.12630,379,140 - 30,379,215 (+)NCBI
UNSW_CanFamBas_1.02630,002,840 - 30,002,915 (+)NCBI
UU_Cfam_GSD_1.02631,092,810 - 31,092,885 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000025669 Ensembl
  ENSCAFG00845026006 ENTREZGENE
Ensembl Transcript ENSCAFT00845045880 ENTREZGENE
miRBase MI0010349 ENTREZGENE
NCBI Gene MIR301B ENTREZGENE
RNAcentral URS0000251D0B RNACentral
  URS00007E4566 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR301B  microRNA mir-301b    microRNA 301b  Symbol and/or name change 5135510 APPROVED