GSDMC (gasdermin C) - Rat Genome Database

Name: GSDMC
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: GSDMC (gasdermin C) Canis lupus familiaris

Analyze

Symbol:

GSDMC

Name:

gasdermin C

RGD ID:

12182357

Description:

ENCODES a protein that exhibits wide pore channel activity (ortholog); INVOLVED IN intestinal epithelial cell development (ortholog); type 2 immune response (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytoplasm (ortholog); plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

gasdermin-C; melanoma-derived leucine zipper, extra-nuclear factor; MLZE

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GSDMC (gasdermin C)	HGNC	HomoloGene, NCBI
Mus musculus (house mouse):	Gsdmc2 (gasdermin C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Gsdmc (gasdermin C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gsdmc (gasdermin C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GSDMC (gasdermin C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gsdmc (gasdermin C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LOC100151870 (gasdermin-C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GSDMC (gasdermin C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gsdmc (gasdermin C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	26,906,167 - 26,919,599 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	26,907,120 - 26,919,353 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	26,874,947 - 26,893,488 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	27,251,396 - 27,270,024 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	13	26,968,131 - 26,986,664 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	27,088,481 - 27,107,014 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	27,388,369 - 27,406,918 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

defense response to bacterium (IEA)

intestinal epithelial cell development (ISO)

programmed cell death (IEA)

pyroptosis (IEA)

type 2 immune response (ISO)

Cellular Component

cytoplasm (ISO)

membrane (IEA)

plasma membrane (ISO)

Molecular Function

phosphatidylinositol-4,5-bisphosphate binding (IEA)

phosphatidylinositol-4-phosphate binding (IEA)

phosphatidylserine binding (IEA)

wide pore channel activity (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

GSDMC
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	26,906,167 - 26,919,599 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	26,907,120 - 26,919,353 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	26,874,947 - 26,893,488 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	27,251,396 - 27,270,024 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	13	26,968,131 - 26,986,664 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	27,088,481 - 27,107,014 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	27,388,369 - 27,406,918 (+)	NCBI		UU_Cfam_GSD_1.0

GSDMC
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	129,705,435 - 129,786,624 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	129,748,196 - 129,786,624 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	130,760,442 - 130,798,870 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	130,829,624 - 130,868,316 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	130,829,624 - 130,868,316	NCBI
Celera	8	126,938,559 - 126,977,251 (-)	NCBI		Celera
Cytogenetic Map	8	q24.21	NCBI
HuRef	8	126,079,087 - 126,117,763 (-)	NCBI		HuRef
CHM1_1	8	130,800,680 - 130,839,374 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	130,831,881 - 130,912,619 (-)	NCBI		T2T-CHM13v2.0

Gsdmc2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	63,696,177 - 63,717,042 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	63,696,195 - 63,717,026 (-)	Ensembl		GRCm39 Ensembl
GRCm38	15	63,824,328 - 63,845,193 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	63,824,346 - 63,845,177 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	63,655,901 - 63,676,731 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	63,654,012 - 63,674,842 (-)	NCBI		MGSCv36	mm8
Celera	15	65,329,697 - 65,340,197 (-)	NCBI		Celera
Cytogenetic Map	15	D1	NCBI
cM Map	15	27.91	NCBI

Gsdmc
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	97,482,713 - 97,509,985 (-)	NCBI		GRCr8
mRatBN7.2	7	95,594,015 - 95,606,106 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	95,594,015 - 95,611,344 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	97,365,121 - 97,377,211 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	99,566,785 - 99,578,877 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	99,488,732 - 99,500,834 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	104,474,418 - 104,492,373 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	104,474,418 - 104,486,710 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	91,477,763 - 91,495,324 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	101,108,796 - 101,120,887 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	101,143,025 - 101,155,117 (-)	NCBI
Celera	7	92,191,820 - 92,203,910 (-)	NCBI		Celera
Cytogenetic Map	7	q33	NCBI

Gsdmc
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955461	4,594,967 - 4,610,037 (+)	NCBI	ChiLan1.0	ChiLan1.0

GSDMC
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	147,116,760 - 147,155,267 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	122,633,411 - 122,672,081 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	126,384,575 - 126,423,505 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	129,118,142 - 129,157,082 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	129,118,445 - 129,147,808 (-)	Ensembl	panpan1.1		panPan2

Gsdmc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	11,407,434 - 11,430,055 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	18,843,579 - 18,855,639 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	18,840,455 - 18,856,022 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LOC100151870
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	4	10,724,754 - 10,744,226 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	11,095,423 - 11,113,844 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GSDMC
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	124,247,934 - 124,291,282 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666039	15,833,792 - 15,867,380 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gsdmc
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624735	25,913,246 - 25,955,621 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in GSDMC
166 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium
Low							4				3
Below cutoff	5	5	22	6	6	6	2	6	12	8	7	6

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_022427118	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038494052	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038556341	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038619015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038684635	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000137	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000361	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000001658 ⟹ ENSCAFP00000001525

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	13	26,907,120 - 26,919,353 (+)	Ensembl

RefSeq Acc Id:

XM_022427118 ⟹ XP_022282826

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	13	26,906,167 - 26,919,599 (+)	NCBI
Dog10K_Boxer_Tasha	13	26,874,947 - 26,893,488 (+)	NCBI

Sequence:

show sequence

ACTCCTTCACATTCCTTATTCATCTCCCTCTCTAGCAAACAACTCATTTCAGAATTATTATTGC
TGATGTCTACATGGCACTTTCCTGACTCAAAGTGTCAGAGCTTTGAGTAGCCACTGGGACCACC
TCACCACACCACTCCTTTTGTAGATGCTGGCTCTGCCTTCAACACAGACCAGGACCCAATCACT
TCCCATCTCACTGTCTGTGCCAGCACCCTGGCCTCATCCCCCATCAGCTCTCACTAGGGTCACC
GCAGTCCCTCCTAACCAGACTCCCTACTTCTGCTCCTACTGCCTTACTATGTCTGTCTGTGGAC
AACACAACAAAGACTGGCATCTTTTCCAAAGACGTGTCCCACTTGTCACTCTTGAGCTCACTCC
CCTCCGACAGCTGCCAGTCCCACTTCAAGTAAAAACCAAGTCCTAACCATGTGCAACAAGGGCC
TGCCCCCACCTGCCCTCCCTGCCTGATGAATTCGCTCAGGCACTGCGCCTGGGCTGGCGCCAGG
TACTTCTTCCTGTAGGATCTCTGCTCTTCCTCATTCCTCCTTTCCCCAGACAGCCACATAGTTC
ATGTCCTCCCCACATTCTTCCAGTTCCAGTCTTTGTTCAAATGTCACGTTCCAGTGAGGCCTTC
ACTTTCTCCTTGCAAACACTGCCCCCACTTCCACCACCACCACCATGAATTTTTAACATGTACC
TAACTTCCTTTCAGGCCCTTCTGCTGATGACAGTATAGGGTACTTCCTGGTCCTTTAGAGTGCC
GTTGGGCTGGGGCTGGGGGCACACACAGGCTTTTCTATTCTAGCCCAAAGAGCAATGAATTTCA
CAACACTGCTTTCCTCCAAAGCCTAGGCTGTGTTTAGAATACCAAAGTTGAGAAAATTATGATC
TAGTCACCATTCTAAGTTAAGACCAAAGTTAATCTCATAAATTTGCTCTTTCTTTAGGAAAAAT
ATCAAGCTCCGTGGGAGCTTCCCCTCTCAACTGAATTTTGGACTCCCCTTCTACCTGTTCCTAG
AAACATGCCCTCCCTCTTTGAGCATATTAGCAAGAACTTGGTCAGAGAGCTTGGAGACAAAGAC
CTGAGGCCCATGAGATGCCTGTCAAATGCCAACCAATTCCGTCAGCTGGCAATATTACAGAAGA
GGAAGAAGCGCTCACCCTTCTGGGAACAACCTGACATTCCAGCCGAATACACCCTCATGGACCT
CCTGGAGCCAAGTTCTTCAGTTCCCGAAACTGCTGTCATGGGACCGTTTCTCTTCAGTGACACT
GTGGTCCAGCAGGGACAGGTTTCTGCCAACGTGACCACTGGGCTAGAAATGAATGTGTCAGGGA
AAGCTACTGTGTTCCATGGATCCTCCCTTCAGTTTCAGGCTGTTACCATCCCACCCCATAACTG
GAAAGACCTTCAAAAGAGGAAAGTGCAAGATCCAGAGCTGCTATTTCTGGTGAAGTGCCGGGAC
AGACAGGATAATCTCTATGTGGTGACAGACACCGTGGAACTGACCGACACTACTGTGCTTTGTG
ACAACAGAAGTGTGAATGTTTGGGGAAGCTGCTTTCTCCCTTTTGATACTTTCTTCAAGGGTCG
AGGCCAGGGAGAGGGTCTAAAAGTGAGAGAGAAGACACTGATTCTGCCACAGGGCACAGTGATG
GCCTACAAGAGGAAGCAGCTGGTTTTTAAGGAGAATGGCTGGGATATTCTCATCTCAGATGACG
ACAAGGAGAAGACCTTTCCAGAAGAGAAACTGCGCATGCAGTCGAAATCACTTCCAAGCACCAT
CAACAGTGGTTTCATCCCTCCAAGAGGTGAATATGTGTTTGCTGGAGGAAGAACACAGGAACCT
TTTAGGCAAGATTTCAAGCAACTACATGAAGAGATTTTCCAGGAAGTGGAGGCCCTGGACGAGC
TCTCAAAGGACACTCAGGATGCCATATTCCATAATATCCTGAACACGCTTGGGAACCGAAAGGC
TTTGCTGGAACTTATGGACAGGCTGGATGGGGACCCCTTTGATCCTTTGGATGGCTTTGGTGGC
GAAATCCTAAATGAGACACAAGAAGACACAAGAAATCTATGGATCCAGGGAAGATCCTCCATCA
TTTACCTCCTCGAAGCCATAATAGTGCTGAGTGATACCCAACACAATCTGCTGGCCCAGTCCAT
GAAGAAGAGGATCCTCCTCCAGCAGCAGGAGCTGGTAAGGAGCATCCTGGAGCCCAACTTCAAA
TACCCTTGGAACATCCCCTTCACCCTCAAACCTGAGCTCCTTGCCCCACTCCAGGGTGAAGGTC
TGGCCATCACCTATGGCCTGCTGCAGGAGTGTGGCCTGAATATAGAGCTGAATAGTCCCAGGTC
AACCTGGGATCTGGAAGTCAAGCAGCCCCTGTCTGCCCTGTATGCGACCCTTTCCATGCTGCAG
CAGCTAGCAGGCAGTCAGAGAGGCCAGGCCCTACCAGTCTATACTGGAAGTGTCCCTGGTGAGC
TCAGAGGACTTAGGACCACAACTTCTGCCACTCTAGGTCAGACACAGCCAGGAGTCAGTAGACT
TGAGGGAATGTTCTGAAATCACAGAAAGATCTGTACCTTGATGAAGATTCATGCAATTGTCAAA
ACTCATCAAATAGTATCTAAAGATGTGAGCATTTCGCTGTATAGCAATGTTACTCCAAAACAAT
GTAAACCAATATTAAACTCCAGTAACAATATGAATTGTTTGGGGTGAGGTGTACTGGTATCAGC
AACTTACTTTGAAATACATCATAAGGGACGCCTGGCTGGCTCAGTGGTTGAGCATCTGCCTTTA
GCTCAG

hide sequence

RefSeq Acc Id:

XM_038494052 ⟹ XP_038349980

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	13	26,968,131 - 26,986,664 (+)	NCBI

RefSeq Acc Id:

XM_038556341 ⟹ XP_038412269

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	13	27,388,369 - 27,406,918 (+)	NCBI

RefSeq Acc Id:

XM_038619015 ⟹ XP_038474943

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	13	27,088,481 - 27,107,014 (+)	NCBI

RefSeq Acc Id:

XM_038684635 ⟹ XP_038540563

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	13	27,251,396 - 27,270,024 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_022282826	(Get FASTA)	NCBI Sequence Viewer
	XP_038349980	(Get FASTA)	NCBI Sequence Viewer
	XP_038412269	(Get FASTA)	NCBI Sequence Viewer
	XP_038474943	(Get FASTA)	NCBI Sequence Viewer
	XP_038540563	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000001525.5
	ENSCAFP00845017725.1

RefSeq Acc Id:

XP_022282826 ⟸ XM_022427118

- Peptide Label:

isoform X1

- Sequence:

show sequence

MPSLFEHISKNLVRELGDKDLRPMRCLSNANQFRQLAILQKRKKRSPFWEQPDIPAEYTLMDLL
EPSSSVPETAVMGPFLFSDTVVQQGQVSANVTTGLEMNVSGKATVFHGSSLQFQAVTIPPHNWK
DLQKRKVQDPELLFLVKCRDRQDNLYVVTDTVELTDTTVLCDNRSVNVWGSCFLPFDTFFKGRG
QGEGLKVREKTLILPQGTVMAYKRKQLVFKENGWDILISDDDKEKTFPEEKLRMQSKSLPSTIN
SGFIPPRGEYVFAGGRTQEPFRQDFKQLHEEIFQEVEALDELSKDTQDAIFHNILNTLGNRKAL
LELMDRLDGDPFDPLDGFGGEILNETQEDTRNLWIQGRSSIIYLLEAIIVLSDTQHNLLAQSMK
KRILLQQQELVRSILEPNFKYPWNIPFTLKPELLAPLQGEGLAITYGLLQECGLNIELNSPRST
WDLEVKQPLSALYATLSMLQQLAGSQRGQALPVYTGSVPGELRGLRTTTSATLGQTQPGVSRLE
GMF

hide sequence

RefSeq Acc Id:

ENSCAFP00000001525 ⟸ ENSCAFT00000001658

RefSeq Acc Id:	XP_038349980 ⟸ XM_038494052
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038474943 ⟸ XM_038619015
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038540563 ⟸ XM_038684635
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038412269 ⟸ XM_038556341
- Peptide Label:	isoform X3

Protein Domains

Gasdermin pore forming Gasdermin PUB

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000001087	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00845012688	UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000001658.5	UniProtKB/TrEMBL
	ENSCAFT00845022589.1	UniProtKB/TrEMBL
InterPro	Gasdermin_pore	UniProtKB/TrEMBL
	Gasdermin_PUB	UniProtKB/TrEMBL
NCBI Gene	GSDMC	ENTREZGENE
PANTHER	GASDERMIN-C	UniProtKB/TrEMBL
	PTHR16399	UniProtKB/TrEMBL
Pfam	Gasdermin	UniProtKB/TrEMBL
	Gasdermin_C	UniProtKB/TrEMBL
UniProt	A0A8I3NHJ1_CANLF	UniProtKB/TrEMBL
	A0A8P0S705_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:49925	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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