MFSD5 (major facilitator superfamily domain containing 5) - Rat Genome Database

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Gene: MFSD5 (major facilitator superfamily domain containing 5) Canis lupus familiaris
Analyze
Symbol: MFSD5
Name: major facilitator superfamily domain containing 5
RGD ID: 12182315
Description: ENCODES a protein that exhibits molybdate ion transmembrane transporter activity (inferred); INVOLVED IN molybdate ion transport (inferred); monoatomic ion transport (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: major facilitator superfamily domain-containing protein 5; molybdate-anion transporter
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,941,446 - 1,943,787 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,941,691 - 1,943,043 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2744,305,511 - 44,307,839 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0271,945,938 - 1,948,266 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl271,945,944 - 1,948,289 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1271,964,198 - 1,966,526 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0271,949,122 - 1,951,437 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02744,706,197 - 44,708,525 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MFSD5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,941,446 - 1,943,787 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,941,691 - 1,943,043 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2744,305,511 - 44,307,839 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0271,945,938 - 1,948,266 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl271,945,944 - 1,948,289 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1271,964,198 - 1,966,526 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0271,949,122 - 1,951,437 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02744,706,197 - 44,708,525 (+)NCBIUU_Cfam_GSD_1.0
MFSD5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381253,251,197 - 53,254,406 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1253,251,251 - 53,254,406 (+)EnsemblGRCh38hg38GRCh38
GRCh371253,645,370 - 53,648,190 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361251,932,147 - 51,934,455 (+)NCBINCBI36Build 36hg18NCBI36
Celera1253,294,460 - 53,297,280 (+)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1250,687,071 - 50,689,891 (+)NCBIHuRef
CHM1_11253,611,667 - 53,614,487 (+)NCBICHM1_1
T2T-CHM13v2.01253,216,787 - 53,219,996 (+)NCBIT2T-CHM13v2.0
Mfsd5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915102,187,891 - 102,190,179 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15102,187,889 - 102,190,189 (+)EnsemblGRCm39 Ensembl
GRCm3815102,279,456 - 102,281,744 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15102,279,454 - 102,281,754 (+)EnsemblGRCm38mm10GRCm38
MGSCv3715102,109,887 - 102,112,175 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615102,107,488 - 102,109,778 (+)NCBIMGSCv36mm8
Celera15104,436,913 - 104,439,201 (+)NCBICelera
Cytogenetic Map15F2NCBI
cM Map1557.44NCBI
Mfsd5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,287,683 - 135,289,964 (+)NCBIGRCr8
mRatBN7.27133,409,096 - 133,411,377 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,402,537 - 133,411,396 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7135,170,118 - 135,172,399 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,399,498 - 137,401,779 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,384,540 - 137,386,821 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07143,882,000 - 143,884,281 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7143,882,000 - 143,884,280 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,678,906 - 141,681,187 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47141,032,928 - 141,035,209 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17141,109,434 - 141,111,641 (+)NCBI
Celera7129,842,507 - 129,844,808 (+)NCBICelera
Cytogenetic Map7q36NCBI
Mfsd5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955458519,566 - 521,778 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955458519,566 - 521,778 (+)NCBIChiLan1.0ChiLan1.0
MFSD5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21040,931,577 - 40,935,260 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11240,928,342 - 40,932,028 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01235,499,848 - 35,502,163 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11236,280,077 - 36,282,391 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1236,280,077 - 36,283,227 (-)Ensemblpanpan1.1panPan2
Mfsd5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494562,616,748 - 62,619,070 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651210,545,758 - 10,548,067 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651210,545,758 - 10,548,067 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MFSD5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,476,366 - 18,478,737 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1518,476,366 - 18,478,745 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2518,912,089 - 18,914,471 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MFSD5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11149,359,286 - 49,362,027 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1149,360,455 - 49,361,807 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037196,697,445 - 196,700,570 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mfsd5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249041,296,292 - 1,298,379 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249041,296,224 - 1,298,419 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MFSD5
22 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 22 6 6 6 6 12 10 6
Low 5 6 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000011278   ⟹   ENSCAFP00000010448
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl271,941,691 - 1,943,043 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845037184   ⟹   ENSCAFP00845029119
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl271,945,944 - 1,948,289 (-)Ensembl
RefSeq Acc Id: XM_038438070   ⟹   XP_038293998
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0271,945,938 - 1,948,266 (-)NCBI
RefSeq Acc Id: XM_038512770   ⟹   XP_038368698
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1271,964,198 - 1,966,526 (-)NCBI
RefSeq Acc Id: XM_038576179   ⟹   XP_038432107
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02744,706,197 - 44,708,525 (+)NCBI
RefSeq Acc Id: XM_038640319   ⟹   XP_038496247
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0271,949,122 - 1,951,437 (-)NCBI
RefSeq Acc Id: XM_844743   ⟹   XP_849836
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1271,941,446 - 1,943,787 (-)NCBI
Dog10K_Boxer_Tasha2744,305,511 - 44,307,839 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_849836   ⟸   XM_844743
- UniProtKB: A0A8C0TH98 (UniProtKB/TrEMBL),   A0A8C0L540 (UniProtKB/TrEMBL),   A0A8I3S251 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000010448   ⟸   ENSCAFT00000011278
RefSeq Acc Id: XP_038368698   ⟸   XM_038512770
RefSeq Acc Id: XP_038496247   ⟸   XM_038640319
RefSeq Acc Id: XP_038293998   ⟸   XM_038438070
- UniProtKB: A0A8C0TH98 (UniProtKB/TrEMBL),   A0A8C0L540 (UniProtKB/TrEMBL),   A0A8I3S251 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038432107   ⟸   XM_038576179
- UniProtKB: A0A8C0L540 (UniProtKB/TrEMBL),   A0A8C0TH98 (UniProtKB/TrEMBL),   A0A8I3S251 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845029119   ⟸   ENSCAFT00845037184


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000007035 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030025159 UniProtKB/TrEMBL
  ENSCAFG00040022014 UniProtKB/TrEMBL
  ENSCAFG00845021076 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000011278.4 UniProtKB/TrEMBL
  ENSCAFT00030046425.1 UniProtKB/TrEMBL
  ENSCAFT00040040865.1 UniProtKB/TrEMBL
  ENSCAFT00845037184 ENTREZGENE
  ENSCAFT00845037184.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/TrEMBL
InterPro MFS_trans_sf UniProtKB/TrEMBL
  MOT2/MFSD5 UniProtKB/TrEMBL
KEGG Report cfa:607891 UniProtKB/TrEMBL
NCBI Gene MFSD5 ENTREZGENE
PANTHER MOLYBDATE-ANION TRANSPORTER UniProtKB/TrEMBL
  PTHR23516 UniProtKB/TrEMBL
Pfam MFS_5 UniProtKB/TrEMBL
Superfamily-SCOP SSF103473 UniProtKB/TrEMBL
UniProt A0A8C0L540 ENTREZGENE
  A0A8C0TH98 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S251 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:43204 ENTREZGENE