ADA2 (adenosine deaminase 2) - Rat Genome Database

Name: ADA2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: ADA2 (adenosine deaminase 2) Canis lupus familiaris

Analyze

Symbol:

ADA2

Name:

adenosine deaminase 2 (Ensembl:haloacid dehalogenase like hydrolase domain containing 5)

RGD ID:

12182104

Description:

ENCODES a protein that exhibits adenosine receptor binding (ortholog); protein homodimerization activity (ortholog); proteoglycan binding (ortholog); INVOLVED IN adenosine catabolic process (inferred); glycerophospholipid biosynthetic process (inferred); inosine biosynthetic process (inferred); ASSOCIATED WITH ataxia telangiectasia (ortholog); Behcet's disease (ortholog); Chediak-Higashi syndrome (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred); mitochondrion (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

adenosine deaminase CECR1; cat eye syndrome chromosome region, candidate 1; CECR1

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ADA2 (adenosine deaminase 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Chinchilla lanigera (long-tailed chinchilla):	Ada2 (adenosine deaminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ADA2 (adenosine deaminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ada2 (adenosine deaminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ADA2 (adenosine deaminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ada2 (adenosine deaminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	HDHD5 (haloacid dehalogenase like hydrolase domain containing 5)	HGNC	Ensembl

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	44,883,573 - 44,912,930 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	44,884,882 - 44,912,850 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	1,769,205 - 1,797,072 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	45,252,821 - 45,282,830 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	45,213,505 - 45,282,723 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	45,182,081 - 45,212,030 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	45,155,035 - 45,185,006 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	1,123,391 - 1,153,447 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

ataxia telangiectasia (ISO)

Behcet's disease (ISO)

Chediak-Higashi syndrome (ISO)

COVID-19 (ISO)

immunodeficiency 51 (ISO)

Neurodevelopmental Disorders (ISO)

pleural tuberculosis (ISO)

polyarteritis nodosa (ISO)

Polyarteritis Nodosa, Childhood-Onset (ISO)

primary immunodeficiency disease (ISO)

pulmonary tuberculosis (ISO)

Sneddon syndrome (ISO)

Splenomegaly (ISO)

Stroke (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenosine catabolic process (IEA)

glycerophospholipid biosynthetic process (IEA)

inosine biosynthetic process (IEA)

Cellular Component

extracellular region (IEA)

extracellular space (IEA)

mitochondrion (IEA)

Molecular Function

adenosine deaminase activity (IEA)

adenosine receptor binding (ISO)

deaminase activity (IEA)

hydrolase activity (IEA)

metal ion binding (IEA)

protein homodimerization activity (ISO)

proteoglycan binding (ISO)

zinc ion binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202	PMID:37756605

Genomics

Comparative Map Data

ADA2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	44,883,573 - 44,912,930 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	44,884,882 - 44,912,850 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	1,769,205 - 1,797,072 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	45,252,821 - 45,282,830 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	45,213,505 - 45,282,723 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	45,182,081 - 45,212,030 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	45,155,035 - 45,185,006 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	1,123,391 - 1,153,447 (+)	NCBI		UU_Cfam_GSD_1.0

ADA2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	17,178,790 - 17,221,848 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	17,178,790 - 17,258,235 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	22	17,659,680 - 17,702,738 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	16,040,192 - 16,070,779 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	22	16,034,745 - 16,055,099	NCBI
Celera	22	1,281,480 - 1,312,039 (-)	NCBI		Celera
Cytogenetic Map	22	q11.1	NCBI
HuRef	22	1,478,307 - 1,508,882 (-)	NCBI		HuRef
CHM1_1	22	17,664,680 - 17,695,177 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	22	17,855,301 - 17,898,324 (-)	NCBI		T2T-CHM13v2.0

Ada2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955454	5,341,822 - 5,355,383 (-)	NCBI	ChiLan1.0	ChiLan1.0

ADA2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	27,492,759 - 27,533,657 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	30,042,958 - 30,083,867 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	606,220 - 648,902 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	16,042,295 - 16,127,103 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	22	16,042,295 - 16,081,949 (-)	Ensembl	panpan1.1		panPan2

Ada2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	110,683,650 - 110,713,247 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936807	232,851 - 262,593 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ADA2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	69,526,435 - 69,554,661 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	69,526,413 - 69,554,640 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

Ada2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624735	10,023,330 - 10,052,600 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in ADA2
311 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium					6
Low	5	1	22	6		6	6		12	8	10	6
Below cutoff		4						6

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_022411277	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022411278	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038439511	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038439512	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038439513	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038439514	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038459575	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038459576	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038459577	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038514153	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038514154	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038514156	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038514157	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038576261	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038576262	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038576263	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038576264	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038642015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038642016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038642017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038642018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_849704	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000027	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000289	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000069	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000027	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000025571 ⟹ ENSCAFP00000023745

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	27	44,884,882 - 44,912,850 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845054386 ⟹ ENSCAFP00845042734

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	27	45,213,505 - 45,271,469 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845054390 ⟹ ENSCAFP00845042738

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	27	45,213,505 - 45,234,002 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845054400 ⟹ ENSCAFP00845042746

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	27	45,253,965 - 45,282,554 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845054408 ⟹ ENSCAFP00845042755

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	27	45,253,980 - 45,282,723 (-)	Ensembl

RefSeq Acc Id:

XM_038439511 ⟹ XP_038295439

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	27	45,253,161 - 45,282,827 (-)	NCBI

RefSeq Acc Id:

XM_038439512 ⟹ XP_038295440

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	27	45,253,958 - 45,282,827 (-)	NCBI

RefSeq Acc Id:

XM_038439513 ⟹ XP_038295441

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	27	45,253,049 - 45,282,827 (-)	NCBI

RefSeq Acc Id:

XM_038439514 ⟹ XP_038295442

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	27	45,252,821 - 45,282,830 (-)	NCBI

RefSeq Acc Id:

XM_038459575 ⟹ XP_038315503

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	27	1,769,205 - 1,797,072 (+)	NCBI

RefSeq Acc Id:

XM_038459576 ⟹ XP_038315504

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	27	1,769,226 - 1,797,072 (+)	NCBI

RefSeq Acc Id:

XM_038459577 ⟹ XP_038315505

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	27	1,780,349 - 1,797,072 (+)	NCBI

RefSeq Acc Id:

XM_038514153 ⟹ XP_038370081

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	27	45,182,383 - 45,212,027 (-)	NCBI

RefSeq Acc Id:

XM_038514154 ⟹ XP_038370082

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	27	45,183,180 - 45,212,027 (-)	NCBI

RefSeq Acc Id:

XM_038514156 ⟹ XP_038370084

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	27	45,182,271 - 45,212,027 (-)	NCBI

RefSeq Acc Id:

XM_038514157 ⟹ XP_038370085

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	27	45,182,081 - 45,212,030 (-)	NCBI

RefSeq Acc Id:

XM_038576261 ⟹ XP_038432189

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	27	1,123,394 - 1,153,110 (+)	NCBI

RefSeq Acc Id:

XM_038576262 ⟹ XP_038432190

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	27	1,123,394 - 1,152,309 (+)	NCBI

RefSeq Acc Id:

XM_038576263 ⟹ XP_038432191

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	27	1,123,394 - 1,153,213 (+)	NCBI

RefSeq Acc Id:

XM_038576264 ⟹ XP_038432192

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	27	1,123,391 - 1,153,447 (+)	NCBI

RefSeq Acc Id:

XM_038642015 ⟹ XP_038497943

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	27	45,155,352 - 45,185,003 (-)	NCBI

RefSeq Acc Id:

XM_038642016 ⟹ XP_038497944

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	27	45,156,152 - 45,185,003 (-)	NCBI

RefSeq Acc Id:

XM_038642017 ⟹ XP_038497945

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	27	45,155,236 - 45,185,003 (-)	NCBI

RefSeq Acc Id:

XM_038642018 ⟹ XP_038497946

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	27	45,155,035 - 45,185,006 (-)	NCBI

RefSeq Acc Id:

XM_849704 ⟹ XP_854797

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	27	44,884,056 - 44,912,930 (-)	NCBI
Dog10K_Boxer_Tasha	27	1,769,205 - 1,797,072 (+)	NCBI

Sequence:

show sequence

AGAGGAAGTGAAACCTGCCCCGACAGGAAGTGAAAACAGGATGGTGAGCTTTTCTGGTGCCTCT
GACACAGCTGTTGGGGGCACTCAGCAAACAGTGCGCAGTTTTTGGAGCTGCTCTGAGGCATCCC
AATGTCTGTGGGTGGCCCATCAGGGCGGCCAGCCCTGCTCTCTCTGCTTCTGATGGTGGCAACA
TCTGTTTTCTGCTCAACCATGTCCATAGATGAAGCACGAACCCAGCTATTGATGCGAGAGAGGA
TGATGCAGCTGGGGGGGCAGTTGGTGCTGACCCAACAGGAAGAGCTGGCCAACGAGAGGCTCAT
GGCCCTCAAGAAGGCTGAGGTGGCACAGGCCATGAAGACCCACCAGTTCCCCCCAAGCATGCAC
TTTTTCCAGGCCAAGAATCTCATTGAGAAAAGTGAGGTGTTTAACATCCTGAAGAAGATGCCAA
AAGGGGCTGCCTTACACATCCATGACTTCAGTATCCTGAGCATGAACTGGCTGGTGAAAAATGT
CACTTACAGGCCCCACTGCCATTTCTGTATCACCCCAAGGGGGGCGCTGAAGTTCAAATTTGCT
TATCCAGCACCCCCAACCCCTATGCCAGCAGAGTGCTCAGAGTGGGTTTTGCTGGAGAAATATC
GAAAGGAGCTGCAGAATGTCACTGAGTTTGACAACAGACTGCTGAAGAATTTCACTCTGATGAC
TGAGAACCCTGAGGTGGCTTACGCAAACCAAGCTATTGTCTGGTCCAAGTTTCAAAGCATCTTC
TTCACAATTTCTGGCCTTGTCTACTATGCGCCAGTGTTTAGAGACTATGTCTTCCAGGCCCTGG
AGGAGTTCTACCAGGACAATGTGCTCTACCTGGAGCTCAGAGCCATGCTGTTCCCGGTGTATGA
ACTGAATGGGACCGTCCATAGCCGAGAGTGGTCAGTGAGGACTTATAGAGAAGTGGCTTATATG
TTTGCGAAAAAGCATCCTGGGTTCATTGGAATCAAACTCATTTATACGGATCACAGATTTAAAA
ATGTGTCCTTCATCATGAAATCCGTGCAAACAGCCATGGCGCTTCGAACCATGTTCCCCAGGAT
GGTGGCAGGGTTTGACCTGGTGGGGCATGAAGACACTGGCTACTCCTTGTTTGACTACAAGGAG
GCTTTGATGATTCCCACCTTGCATGGTGTTAAACTGCCTTACTTTTTCCATGCTGGAGAGACAG
ATTGGCTGGGTACTTCCATAGATAGAAACCTTCTGGATGCTCTAATACTGAACTCTACCAGGAT
TGGCCATGGATTTGCTTTGACCAAACACCCAGCAGTCTGGGCTGACTCCCGGAAGAAGAACATT
CCCATAGAAGTCTGTCCCATCTCCAATCAGGTTCTGAAACTGGTGTCGGACTTGCGAAACCACC
CTGCTGCTGTCCTGATGGCCACTGGGTATCCCATGGTGATCAGCTCTGATGACCCAGCTATCTT
TGGTGCCAAAGGCTTATCCTATGATTTCTATGAGGCCTTCATGGGCATTGGGGGAATGGAGGCT
GATCTGAGGACACTCAAACAGCTGGCCATGAACTCCATCAAGTTCAGCACCTTGTTGGATATTG
ATAAAAAGGCTGCCATGAAAACCTGGGAGGAGAGATGGGATAAGTTTGTGGCCGACCTGGCCAG
GTGGCCAAAGTGAGAAGATAGCCATTTATTACCATATTCCTCTGCTTTCCTCTGCAAGCTGTTT
TCACCTTTGGTCAGTCAGTCTTGAACCCACTCCAGTATGGTTTCTATCTCCATTTCTTTATCAA
AACTGCCTCATGAAGGTCATCAATGGCCTCCACATTGCTTGACTCTCAGAAACACTTAAACAGT
CTACCAAACTCATCTTTTTGAAATATTATTTTCTCTCAACCTCAGGCCATCAATTTTCTTGGTT
TCCTCCTTTCTCTCTGGCCATTCCTTCCAGGGTCCCTTTTCCAGAGGGTCTTCTCTATCAGATC
TCTGTGTTGAAATTCTTCAGGGCTCAGTTTTGCTGCTTTTTGCTTTTCTGTTCACATCTCTGCT
TCTCTCCTCTACTTTTCTCTCTACTCAATAGTCTTTTTCTAGGTAGTCTCATCCATTCCTTTGC
TTTTAAATATCATTTATTTGCTGATGATCCCCAGTTTATTCACTTGGATGGTTCACAGGAATCT
CAGAAACCTATGTGCAATTCTGAACTTTCAATCTCTTTCCTTTCAATCCTTTCCTGGTCTTTCT
CATCTTGGTAAATGGCACCTCCATCCCATCCCACTGAGTTGCTCTAAGTATAATTTCTCAGCAA
AATTCTTGATACTGCTTTCTTCCCTGTTCCCTACATCAAAATGTACCTTGAATTCTGCACACCT
CTCTATCTGTATTGCTGTTGGCTGAGTTCAAGCCGCTATCACTTCTTGTCTAAGTTATAATAGC
CTCTTAGTTGATCTCTCCTTTCTTCTCTTTGCCTACTTCATTACATTTTTCACAGAGCAATGAC
TTTTTAAAAATTAATTCAGATTACTCCATTGTTTACTACTCAGTGCACTTAGAAAAACTCAAAT
GTTTCAACAGGGCATATAGCATCCTCTGTAACCTGGATTCCTTCCAGCAGCATCCCACCCTAGG
CTCCCCTAGAGCACCAGATTCTGGCCACATTGGTCCTTTGTTCCTCAAATATCTCAAACTCTAT
GCTGCATCAGGGTCTTTTCTCATTCTCATTGCCTGGGAGAGTCTTTCTTTCCACTTTTGTCTAA
CTGACTCCTGTTCACCCTTCAAGCTTCACTTTTAATGTCCCTGTGTCAGAAAAGTTTCCTAGAC
CCCTAACCTGTTAATATCTCTCATGGCACCTTGCTTTTTTTCTTCAAGGAAGGAAATACCATAA
TAATATGGTATTATCTTACCATAATTTGTAATTACGTATTTATTTCTGTGTTTATAGTCTTCAC
TTCCACCAGACTGTAAGCTCCCTGTGGGCAAGTACTGATGATTGTGAATCCAGAGCCTTGCTCC
ATGCCCCAAACCTAGTCAGTACTCAATAAAGGATATGTTGAACGAATGGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_038295439	(Get FASTA)	NCBI Sequence Viewer
	XP_038295440	(Get FASTA)	NCBI Sequence Viewer
	XP_038295441	(Get FASTA)	NCBI Sequence Viewer
	XP_038295442	(Get FASTA)	NCBI Sequence Viewer
	XP_038315503	(Get FASTA)	NCBI Sequence Viewer
	XP_038315504	(Get FASTA)	NCBI Sequence Viewer
	XP_038315505	(Get FASTA)	NCBI Sequence Viewer
	XP_038370081	(Get FASTA)	NCBI Sequence Viewer
	XP_038370082	(Get FASTA)	NCBI Sequence Viewer
	XP_038370084	(Get FASTA)	NCBI Sequence Viewer
	XP_038370085	(Get FASTA)	NCBI Sequence Viewer
	XP_038432189	(Get FASTA)	NCBI Sequence Viewer
	XP_038432190	(Get FASTA)	NCBI Sequence Viewer
	XP_038432191	(Get FASTA)	NCBI Sequence Viewer
	XP_038432192	(Get FASTA)	NCBI Sequence Viewer
	XP_038497943	(Get FASTA)	NCBI Sequence Viewer
	XP_038497944	(Get FASTA)	NCBI Sequence Viewer
	XP_038497945	(Get FASTA)	NCBI Sequence Viewer
	XP_038497946	(Get FASTA)	NCBI Sequence Viewer
	XP_854797	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000023745.4
	ENSCAFP00030042449.1
	ENSCAFP00040029663.1
	ENSCAFP00845042734.1
	ENSCAFP00845042746
	ENSCAFP00845042746.1
	ENSCAFP00845042755.1

RefSeq Acc Id:	XP_854797 ⟸ XM_849704
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0T1G5 (UniProtKB/TrEMBL), A0A8I3QB41 (UniProtKB/TrEMBL), A0A8I3S7Q3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSVGGPSGRPALLSLLLMVATSVFCSTMSIDEARTQLLMRERMMQLGGQLVLTQQEELANERLM ALKKAEVAQAMKTHQFPPSMHFFQAKNLIEKSEVFNILKKMPKGAALHIHDFSILSMNWLVKNV TYRPHCHFCITPRGALKFKFAYPAPPTPMPAECSEWVLLEKYRKELQNVTEFDNRLLKNFTLMT ENPEVAYANQAIVWSKFQSIFFTISGLVYYAPVFRDYVFQALEEFYQDNVLYLELRAMLFPVYE LNGTVHSREWSVRTYREVAYMFAKKHPGFIGIKLIYTDHRFKNVSFIMKSVQTAMALRTMFPRM VAGFDLVGHEDTGYSLFDYKEALMIPTLHGVKLPYFFHAGETDWLGTSIDRNLLDALILNSTRI GHGFALTKHPAVWADSRKKNIPIEVCPISNQVLKLVSDLRNHPAAVLMATGYPMVISSDDPAIF GAKGLSYDFYEAFMGIGGMEADLRTLKQLAMNSIKFSTLLDIDKKAAMKTWEERWDKFVADLAR WPK hide sequence

RefSeq Acc Id:

ENSCAFP00000023745 ⟸ ENSCAFT00000025571

RefSeq Acc Id:	XP_038370085 ⟸ XM_038514157
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038370084 ⟸ XM_038514156
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038370081 ⟸ XM_038514153
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038370082 ⟸ XM_038514154
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038497946 ⟸ XM_038642018
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038497945 ⟸ XM_038642017
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038497943 ⟸ XM_038642015
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038497944 ⟸ XM_038642016
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038295442 ⟸ XM_038439514
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038295441 ⟸ XM_038439513
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038295439 ⟸ XM_038439511
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I3S7Q3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038295440 ⟸ XM_038439512
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0T1G5 (UniProtKB/TrEMBL), A0A8I3QB41 (UniProtKB/TrEMBL), A0A8I3S7Q3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038315503 ⟸ XM_038459575
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I3S7Q3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038315504 ⟸ XM_038459576
- Peptide Label:	isoform X6
- UniProtKB:	A0A8C0K2X1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038315505 ⟸ XM_038459577
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_038432192 ⟸ XM_038576264
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038432191 ⟸ XM_038576263
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038432189 ⟸ XM_038576261
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I3S7Q3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038432190 ⟸ XM_038576262
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0T1G5 (UniProtKB/TrEMBL), A0A8I3QB41 (UniProtKB/TrEMBL), A0A8I3S7Q3 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845042734 ⟸ ENSCAFT00845054386

RefSeq Acc Id:

ENSCAFP00845042755 ⟸ ENSCAFT00845054408

RefSeq Acc Id:

ENSCAFP00845042746 ⟸ ENSCAFT00845054400

RefSeq Acc Id:

ENSCAFP00845042738 ⟸ ENSCAFT00845054390

Protein Domains

Adenosine deaminase Adenosine/AMP deaminase N-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000016081	UniProtKB/TrEMBL
	ENSCAFG00000016114	Ensembl
	ENSCAFG00030026208	UniProtKB/TrEMBL
	ENSCAFG00040018445	UniProtKB/TrEMBL
	ENSCAFG00845030648	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000025571.5	UniProtKB/TrEMBL
	ENSCAFT00030048499.1	UniProtKB/TrEMBL
	ENSCAFT00040034080.1	UniProtKB/TrEMBL
	ENSCAFT00845054386.1	UniProtKB/TrEMBL
	ENSCAFT00845054400	ENTREZGENE
	ENSCAFT00845054400.1	UniProtKB/TrEMBL
	ENSCAFT00845054408.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.1000	UniProtKB/TrEMBL
	Metal-dependent hydrolases	UniProtKB/TrEMBL
InterPro	A/AMP_deaminase_dom	UniProtKB/TrEMBL
	A_deaminase_N	UniProtKB/TrEMBL
	ADGF	UniProtKB/TrEMBL
	Ado/ade_deaminase	UniProtKB/TrEMBL
	HAD-like_sf	UniProtKB/TrEMBL
	HAD-SF_hydro_IIA	UniProtKB/TrEMBL
	HAD-SF_hydro_IIA_CECR5	UniProtKB/TrEMBL
	HAD_sf	UniProtKB/TrEMBL
	Metal_Hydrolase	UniProtKB/TrEMBL
NCBI Gene	CECR1	ENTREZGENE
PANTHER	ADENOSINE DEAMINASE 2	UniProtKB/TrEMBL
	CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED	UniProtKB/TrEMBL
	HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING 5	UniProtKB/TrEMBL
	PTHR11409	UniProtKB/TrEMBL
Pfam	A_deaminase	UniProtKB/TrEMBL
	A_deaminase_N	UniProtKB/TrEMBL
	Hydrolase_6	UniProtKB/TrEMBL
Superfamily-SCOP	SSF51556	UniProtKB/TrEMBL
	SSF56784	UniProtKB/TrEMBL
UniProt	A0A8C0K2X1	ENTREZGENE
	A0A8C0T1G5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3QB28_CANLF	UniProtKB/TrEMBL
	A0A8I3QB41	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3S7Q3	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:37569	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-02-21	ADA2	adenosine deaminase 2	CECR1	cat eye syndrome chromosome region, candidate 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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