POLDIP2 (DNA polymerase delta interacting protein 2) - Rat Genome Database

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Gene: POLDIP2 (DNA polymerase delta interacting protein 2) Canis lupus familiaris
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Symbol: POLDIP2
Name: DNA polymerase delta interacting protein 2
RGD ID: 12179968
Description: ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN mitochondrion morphogenesis (ortholog); mitotic spindle assembly (ortholog); negative regulation of macroautophagy (ortholog); ASSOCIATED WITH Neointima (ortholog); streptococcal meningitis (ortholog); FOUND IN cell-cell junction (ortholog); cytoplasm (ortholog); midbody (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: polymerase (DNA-directed), delta interacting protein 2; polymerase delta-interacting protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: LOC491878  
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1942,597,792 - 42,607,576 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl942,597,792 - 42,607,576 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha941,754,715 - 41,764,504 (-)NCBI
ROS_Cfam_1.0943,416,944 - 43,426,747 (-)NCBI
ROS_Cfam_1.0 Ensembl943,416,944 - 43,426,773 (-)Ensembl
UMICH_Zoey_3.1942,201,185 - 42,210,981 (-)NCBI
UNSW_CanFamBas_1.0942,492,418 - 42,502,205 (-)NCBI
UU_Cfam_GSD_1.0942,569,460 - 42,579,263 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
POLDIP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1942,597,792 - 42,607,576 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl942,597,792 - 42,607,576 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha941,754,715 - 41,764,504 (-)NCBI
ROS_Cfam_1.0943,416,944 - 43,426,747 (-)NCBI
ROS_Cfam_1.0 Ensembl943,416,944 - 43,426,773 (-)Ensembl
UMICH_Zoey_3.1942,201,185 - 42,210,981 (-)NCBI
UNSW_CanFamBas_1.0942,492,418 - 42,502,205 (-)NCBI
UU_Cfam_GSD_1.0942,569,460 - 42,579,263 (-)NCBI
POLDIP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1728,346,633 - 28,357,527 (-)EnsemblGRCh38hg38GRCh38
GRCh381728,346,633 - 28,357,527 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371726,673,659 - 26,684,550 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361723,697,786 - 23,708,730 (-)NCBINCBI36hg18NCBI36
Build 341723,697,786 - 23,708,693NCBI
Celera1723,535,404 - 23,546,357 (-)NCBI
Cytogenetic Map17q11.2NCBI
HuRef1722,882,056 - 22,893,008 (-)NCBIHuRef
CHM1_11726,736,554 - 26,747,532 (-)NCBICHM1_1
Poldip2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391178,403,007 - 78,413,566 (+)NCBIGRCm39mm39
GRCm39 Ensembl1178,403,019 - 78,413,562 (+)Ensembl
GRCm381178,512,296 - 78,522,736 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,512,193 - 78,522,736 (+)EnsemblGRCm38mm10GRCm38
MGSCv371178,325,798 - 78,336,238 (+)NCBIGRCm37mm9NCBIm37
MGSCv361178,328,491 - 78,338,931 (+)NCBImm8
Celera1188,144,369 - 88,154,809 (+)NCBICelera
Cytogenetic Map11B5NCBI
Poldip2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21063,408,766 - 63,417,605 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1063,407,213 - 63,417,605 (+)Ensembl
Rnor_6.01065,781,994 - 65,790,833 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1065,780,494 - 65,790,272 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01065,852,787 - 65,861,626 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41064,623,181 - 64,632,020 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11064,635,612 - 64,645,643 (+)NCBI
Celera1062,385,321 - 62,394,160 (+)NCBICelera
Cytogenetic Map10q25NCBI
Poldip2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554814,776,721 - 4,785,817 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554814,776,721 - 4,785,817 (+)NCBIChiLan1.0ChiLan1.0
POLDIP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11728,919,291 - 28,929,613 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1728,919,371 - 28,928,682 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01728,416,912 - 28,427,280 (+)NCBIMhudiblu_PPA_v0panPan3
Poldip2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560241,626,091 - 41,634,827 (-)NCBI
SpeTri2.0NW_0049365384,504,039 - 4,512,785 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POLDIP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1244,625,603 - 44,636,289 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11244,626,447 - 44,636,302 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21246,538,915 - 46,548,765 (-)NCBISscrofa10.2Sscrofa10.2susScr3
POLDIP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11622,113,928 - 22,124,637 (-)NCBIChlSab1.1chlSab2
ChlSab1.11622,113,928 - 22,124,637 (-)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660758,004,364 - 8,014,832 (+)NCBIVero_WHO_p1.0
Poldip2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624786943,015 - 961,828 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000029631   ⟹   ENSCAFP00000027538
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl942,597,792 - 42,607,576 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845012515   ⟹   ENSCAFP00845009777
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl943,416,944 - 43,426,747 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845012544   ⟹   ENSCAFP00845009798
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl943,417,310 - 43,426,773 (-)Ensembl
RefSeq Acc Id: NM_001253903   ⟹   NP_001240832
RefSeq Status: VALIDATED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1942,597,792 - 42,607,576 (-)NCBI
Dog10K_Boxer_Tasha941,754,715 - 41,764,504 (-)NCBI
ROS_Cfam_1.0943,416,944 - 43,426,747 (-)NCBI
UMICH_Zoey_3.1942,201,185 - 42,210,981 (-)NCBI
UNSW_CanFamBas_1.0942,492,418 - 42,502,205 (-)NCBI
UU_Cfam_GSD_1.0942,569,460 - 42,579,263 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001240832 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001240832   ⟸   NM_001253903
- UniProtKB: E2QVV7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000027538   ⟸   ENSCAFT00000029631
RefSeq Acc Id: ENSCAFP00845009798   ⟸   ENSCAFT00845012544
RefSeq Acc Id: ENSCAFP00845009777   ⟸   ENSCAFT00845012515
Protein Domains
ApaG

Promoters
RGD ID:13684668
Promoter ID:EPDNEW_C2738
Type:initiation region
Name:POLDIP2_1
Description:DNA polymerase delta interacting protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1942,607,586 - 42,607,646EPDNEW
Damaging Variants


Assembly: CanFam3.1

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
9 42602852 42602853 C T snv Wolf (WO001_895)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000018665 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00845007044 Ensembl, ENTREZGENE
Ensembl Protein ENSCAFP00000027538 UniProtKB/TrEMBL
  ENSCAFP00845009777 ENTREZGENE
Ensembl Transcript ENSCAFT00000029631 UniProtKB/TrEMBL
  ENSCAFT00845012515 ENTREZGENE
Gene3D-CATH 2.60.40.1470 UniProtKB/TrEMBL
InterPro ApaG_domain UniProtKB/TrEMBL
  ApaG_sf UniProtKB/TrEMBL
  Hemimethylated_DNA-bd_dom UniProtKB/TrEMBL
  Hemimethylated_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report cfa:491162 UniProtKB/TrEMBL
NCBI Gene POLDIP2 ENTREZGENE
Pfam DUF525 UniProtKB/TrEMBL
  YccV-like UniProtKB/TrEMBL
PROSITE APAG UniProtKB/TrEMBL
SMART YccV-like UniProtKB/TrEMBL
Superfamily-SCOP SSF110069 UniProtKB/TrEMBL
  SSF141255 UniProtKB/TrEMBL
UniProt E2QVV7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:44777 ENTREZGENE