TERF1 (telomeric repeat binding factor 1) - Rat Genome Database

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Gene: TERF1 (telomeric repeat binding factor 1) Canis lupus familiaris
Analyze
Symbol: TERF1
Name: telomeric repeat binding factor 1
RGD ID: 12177641
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein C-terminus binding (ortholog); telomeric DNA binding (ortholog); INVOLVED IN meiotic telomere clustering (ortholog); response to drug (ortholog); telomeric loop formation (ortholog); ASSOCIATED WITH breast cancer (ortholog); squamous cell carcinoma (ortholog); stomach cancer (ortholog); FOUND IN chromosome, telomeric region (ortholog); nucleolus (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: telomeric repeat-binding factor 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12921,664,378 - 21,701,491 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2921,664,186 - 21,700,495 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2921,929,296 - 21,966,341 (+)NCBI
ROS_Cfam_1.02921,773,860 - 21,811,415 (+)NCBI
UMICH_Zoey_3.12921,832,463 - 21,869,553 (+)NCBI
UNSW_CanFamBas_1.02921,868,610 - 21,906,117 (+)NCBI
UU_Cfam_GSD_1.02922,149,876 - 22,187,001 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

Genomics

Comparative Map Data
TERF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12921,664,378 - 21,701,491 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2921,664,186 - 21,700,495 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2921,929,296 - 21,966,341 (+)NCBI
ROS_Cfam_1.02921,773,860 - 21,811,415 (+)NCBI
UMICH_Zoey_3.12921,832,463 - 21,869,553 (+)NCBI
UNSW_CanFamBas_1.02921,868,610 - 21,906,117 (+)NCBI
UU_Cfam_GSD_1.02922,149,876 - 22,187,001 (+)NCBI
TERF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl873,008,856 - 73,048,123 (+)EnsemblGRCh38hg38GRCh38
GRCh38873,008,856 - 73,048,123 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37873,921,099 - 73,960,358 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36874,083,661 - 74,122,281 (+)NCBINCBI36hg18NCBI36
Build 34874,083,662 - 74,122,281NCBI
Celera869,918,262 - 69,957,163 (+)NCBI
Cytogenetic Map8q21.11NCBI
HuRef869,411,980 - 69,450,876 (+)NCBIHuRef
CHM1_1873,973,943 - 74,012,842 (+)NCBICHM1_1
Terf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,875,634 - 15,914,276 (+)NCBIGRCm39mm39
GRCm39 Ensembl115,875,870 - 15,914,276 (+)Ensembl
GRCm38115,805,546 - 15,844,052 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,805,646 - 15,844,052 (+)EnsemblGRCm38mm10GRCm38
MGSCv37115,795,739 - 15,833,510 (+)NCBIGRCm37mm9NCBIm37
MGSCv36115,790,872 - 15,828,643 (+)NCBImm8
Celera115,750,793 - 15,788,563 (+)NCBICelera
Cytogenetic Map1A3NCBI
cM Map14.88NCBI
Terf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.253,443,103 - 3,472,377 (-)NCBI
Rnor_6.0 Ensembl52,853,459 - 2,882,668 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.052,853,455 - 2,882,731 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.052,843,150 - 2,872,418 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.452,556,918 - 2,586,086 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.152,556,917 - 2,586,086 (-)NCBI
Celera53,039,138 - 3,068,345 (-)NCBICelera
Cytogenetic Map5q11NCBI
Terf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554447,103,552 - 7,150,323 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554447,103,282 - 7,149,450 (-)NCBIChiLan1.0ChiLan1.0
TERF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1871,192,716 - 71,231,648 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0869,545,115 - 69,583,997 (+)NCBIMhudiblu_PPA_v0panPan3
Terf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530357,612,694 - 57,639,199 (-)NCBI
SpeTri2.0NW_0049366481,809,395 - 1,835,890 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TERF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl462,796,999 - 62,831,422 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1462,797,244 - 62,831,459 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2468,341,702 - 68,375,863 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TERF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1868,608,830 - 68,647,220 (+)NCBI
ChlSab1.1 Ensembl868,608,844 - 68,648,171 (+)Ensembl
Vero_WHO_p1.0NW_02366603972,734,995 - 72,774,562 (-)NCBI
Terf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474418,120,677 - 18,156,920 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 12 5 12 8 10
Low 5 5 10 6 6 6 1 6 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005638041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005638042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022412325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038441382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038441383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038515960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038515961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038579519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038579520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038643771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038643772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000012746   ⟹   ENSCAFP00000011804
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2921,664,186 - 21,700,495 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000046114   ⟹   ENSCAFP00000040715
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2921,664,186 - 21,700,495 (+)Ensembl
RefSeq Acc Id: XM_005638041   ⟹   XP_005638098
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12921,664,379 - 21,700,880 (+)NCBI
Dog10K_Boxer_Tasha2921,929,298 - 21,966,341 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005638042   ⟹   XP_005638099
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12921,664,378 - 21,701,491 (+)NCBI
Dog10K_Boxer_Tasha2921,929,296 - 21,966,341 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022412325   ⟹   XP_022268033
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12921,664,378 - 21,701,488 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038441382   ⟹   XP_038297310
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02921,773,862 - 21,811,415 (+)NCBI
RefSeq Acc Id: XM_038441383   ⟹   XP_038297311
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02921,773,860 - 21,811,415 (+)NCBI
RefSeq Acc Id: XM_038515960   ⟹   XP_038371888
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12921,832,465 - 21,869,553 (+)NCBI
RefSeq Acc Id: XM_038515961   ⟹   XP_038371889
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12921,832,463 - 21,869,553 (+)NCBI
RefSeq Acc Id: XM_038579519   ⟹   XP_038435447
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02922,149,878 - 22,187,001 (+)NCBI
RefSeq Acc Id: XM_038579520   ⟹   XP_038435448
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02922,149,876 - 22,187,001 (+)NCBI
RefSeq Acc Id: XM_038643771   ⟹   XP_038499699
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02921,868,612 - 21,906,117 (+)NCBI
RefSeq Acc Id: XM_038643772   ⟹   XP_038499700
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02921,868,610 - 21,906,117 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_005638099   ⟸   XM_005638042
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005638098   ⟸   XM_005638041
- Peptide Label: isoform X1
- UniProtKB: J9P539 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022268033   ⟸   XM_022412325
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCAFP00000011804   ⟸   ENSCAFT00000012746
RefSeq Acc Id: ENSCAFP00000040715   ⟸   ENSCAFT00000046114
RefSeq Acc Id: XP_038371889   ⟸   XM_038515961
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038371888   ⟸   XM_038515960
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038499700   ⟸   XM_038643772
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038499699   ⟸   XM_038643771
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038297311   ⟸   XM_038441383
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038297310   ⟸   XM_038441382
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038435448   ⟸   XM_038579520
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038435447   ⟸   XM_038579519
- Peptide Label: isoform X1
Protein Domains
HTH myb-type

Promoters
RGD ID:13688424
Promoter ID:EPDNEW_C6492
Type:multiple initiation site
Name:TERF1_1
Description:telomeric repeat binding factor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12921,664,397 - 21,664,457EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000007975 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000011804 ENTREZGENE, UniProtKB/TrEMBL
  ENSCAFP00000040715 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000012746 UniProtKB/TrEMBL
  ENSCAFT00000046114 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.210 UniProtKB/TrEMBL
InterPro Homeobox-like UniProtKB/TrEMBL
  Myb_dom UniProtKB/TrEMBL
  SANT/Myb UniProtKB/TrEMBL
  Telomere_rpt-bd_fac_dimer_dom UniProtKB/TrEMBL
  Telomere_rpt-bd_fac_dimer_sf UniProtKB/TrEMBL
  TERF1/2 UniProtKB/TrEMBL
KEGG Report cfa:100684790 UniProtKB/TrEMBL
NCBI Gene TERF1 ENTREZGENE
Pfam Myb_DNA-binding UniProtKB/TrEMBL
  TRF UniProtKB/TrEMBL
PIRSF Telomere_bd-1_Pin2 UniProtKB/TrEMBL
PROSITE HTH_MYB UniProtKB/TrEMBL
SMART SANT UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
  SSF63600 UniProtKB/TrEMBL
UniProt E2R1W7_CANLF UniProtKB/TrEMBL
  J9P539 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:47254 ENTREZGENE