ST6GAL2 (ST6 beta-galactoside alpha-2,6-sialyltransferase 2) - Rat Genome Database

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Gene: ST6GAL2 (ST6 beta-galactoside alpha-2,6-sialyltransferase 2) Canis lupus familiaris
Analyze
Symbol: ST6GAL2
Name: ST6 beta-galactoside alpha-2,6-sialyltransferase 2
RGD ID: 12176095
Description: ENCODES a protein that exhibits beta-galactoside alpha-2,6-sialyltransferase activity (inferred); glycosyltransferase activity (inferred); sialyltransferase activity (inferred); INVOLVED IN carbohydrate metabolic process (inferred); oligosaccharide metabolic process (inferred); protein glycosylation (inferred); ASSOCIATED WITH genetic disease (ortholog); schizophrenia (ortholog); FOUND IN Golgi apparatus (inferred); Golgi cisterna membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: beta-galactoside alpha-2,6-sialyltransferase 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11036,937,945 - 36,976,048 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1036,941,370 - 36,972,012 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1036,824,612 - 36,900,110 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01037,755,486 - 37,831,114 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1037,755,363 - 37,827,110 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11037,489,297 - 37,563,777 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01037,767,531 - 37,842,964 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01037,958,775 - 38,034,449 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
ST6GAL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11036,937,945 - 36,976,048 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1036,941,370 - 36,972,012 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1036,824,612 - 36,900,110 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01037,755,486 - 37,831,114 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1037,755,363 - 37,827,110 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11037,489,297 - 37,563,777 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01037,767,531 - 37,842,964 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01037,958,775 - 38,034,449 (+)NCBIUU_Cfam_GSD_1.0
ST6GAL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382106,801,600 - 106,887,277 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2106,801,600 - 106,887,108 (-)EnsemblGRCh38hg38GRCh38
GRCh372107,418,056 - 107,503,565 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362106,789,538 - 106,869,982 (-)NCBINCBI36Build 36hg18NCBI36
Build 342106,881,623 - 106,962,068NCBI
Celera2101,627,429 - 101,712,930 (-)NCBICelera
Cytogenetic Map2q12.3NCBI
HuRef2101,093,170 - 101,178,717 (-)NCBIHuRef
CHM1_12107,422,384 - 107,507,897 (-)NCBICHM1_1
T2T-CHM13v2.02107,263,027 - 107,350,150 (-)NCBIT2T-CHM13v2.0
St6gal2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391755,752,071 - 55,821,582 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1755,752,383 - 55,821,582 (+)EnsemblGRCm39 Ensembl
GRCm381755,445,118 - 55,514,581 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1755,445,382 - 55,514,581 (+)EnsemblGRCm38mm10GRCm38
MGSCv371755,585,015 - 55,638,524 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361754,921,736 - 54,975,245 (+)NCBIMGSCv36mm8
Celera1758,887,609 - 58,939,032 (+)NCBICelera
Cytogenetic Map17CNCBI
cM Map1728.82NCBI
St6gal2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr899,508,928 - 9,606,900 (+)NCBIGRCr8
mRatBN7.299,181,744 - 9,274,161 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl99,182,399 - 9,269,697 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx912,220,254 - 12,304,588 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0916,458,757 - 16,543,092 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0915,220,705 - 15,305,040 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.096,966,291 - 7,060,499 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl96,966,908 - 7,053,387 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.096,014,371 - 6,113,987 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera94,973,229 - 5,053,987 (+)NCBICelera
Cytogenetic Map9q11NCBI
St6gal2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495547010,936,073 - 10,993,672 (-)NCBIChiLan1.0ChiLan1.0
ST6GAL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21218,860,236 - 18,947,086 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A18,863,010 - 18,948,808 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A92,857,170 - 92,944,262 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A107,959,469 - 108,044,255 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A107,964,544 - 108,044,068 (-)Ensemblpanpan1.1panPan2
St6gal2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629292,892,968 - 92,946,271 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936729487,396 - 502,309 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936729485,835 - 541,671 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ST6GAL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl348,648,858 - 48,723,774 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1348,648,111 - 48,723,779 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2350,724,373 - 50,795,091 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ST6GAL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11410,240,533 - 10,325,019 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1410,243,126 - 10,280,658 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041178,022,670 - 178,109,878 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
St6gal2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474910,309,542 - 10,369,768 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474910,309,701 - 10,369,918 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ST6GAL2
545 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6
Low 1 12 6 6 8 6 2
Below cutoff 5 4 10 6 6 6 6 4 4

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022424542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038488907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038550872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038550873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038550875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038550876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038614788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038643476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038643477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038643479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038643480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038680157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038680158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038680159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038680160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000003291   ⟹   ENSCAFP00000003057
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1036,941,370 - 36,972,012 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845016167   ⟹   ENSCAFP00845012575
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1037,755,363 - 37,827,110 (+)Ensembl
RefSeq Acc Id: XM_038488907   ⟹   XP_038344835
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11037,489,297 - 37,563,777 (+)NCBI
RefSeq Acc Id: XM_038550872   ⟹   XP_038406800
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01037,959,933 - 38,034,436 (+)NCBI
RefSeq Acc Id: XM_038550873   ⟹   XP_038406801
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01037,958,775 - 38,034,436 (+)NCBI
RefSeq Acc Id: XM_038550875   ⟹   XP_038406803
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01037,959,933 - 38,034,449 (+)NCBI
RefSeq Acc Id: XM_038550876   ⟹   XP_038406804
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01037,959,933 - 38,022,431 (+)NCBI
RefSeq Acc Id: XM_038614788   ⟹   XP_038470716
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01037,767,531 - 37,842,964 (+)NCBI
RefSeq Acc Id: XM_038643476   ⟹   XP_038499404
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1036,825,768 - 36,900,097 (+)NCBI
RefSeq Acc Id: XM_038643477   ⟹   XP_038499405
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1036,824,612 - 36,900,097 (+)NCBI
RefSeq Acc Id: XM_038643479   ⟹   XP_038499407
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1036,825,768 - 36,900,110 (+)NCBI
RefSeq Acc Id: XM_038643480   ⟹   XP_038499408
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1036,825,768 - 36,888,093 (+)NCBI
RefSeq Acc Id: XM_038680157   ⟹   XP_038536085
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01037,756,644 - 37,831,114 (+)NCBI
RefSeq Acc Id: XM_038680158   ⟹   XP_038536086
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01037,755,486 - 37,831,114 (+)NCBI
RefSeq Acc Id: XM_038680159   ⟹   XP_038536087
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01037,756,644 - 37,827,094 (+)NCBI
RefSeq Acc Id: XM_038680160   ⟹   XP_038536088
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01037,756,644 - 37,819,123 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000003057   ⟸   ENSCAFT00000003291
RefSeq Acc Id: XP_038344835   ⟸   XM_038488907
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038470716   ⟸   XM_038614788
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038536086   ⟸   XM_038680158
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KBE9 (UniProtKB/TrEMBL),   A0A8I3RV22 (UniProtKB/TrEMBL),   A0A8C0QG22 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038536085   ⟸   XM_038680157
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KBE9 (UniProtKB/TrEMBL),   A0A8I3RV22 (UniProtKB/TrEMBL),   A0A8C0QG22 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038536087   ⟸   XM_038680159
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KBE9 (UniProtKB/TrEMBL),   A0A8I3RV22 (UniProtKB/TrEMBL),   A0A8C0QG22 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038536088   ⟸   XM_038680160
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QG22 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038499405   ⟸   XM_038643477
- Peptide Label: isoform X2
- UniProtKB: A0A8C0P466 (UniProtKB/TrEMBL),   A0A8P0S899 (UniProtKB/TrEMBL),   A0A8C0QG22 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038499407   ⟸   XM_038643479
- Peptide Label: isoform X2
- UniProtKB: A0A8C0P466 (UniProtKB/TrEMBL),   A0A8P0S899 (UniProtKB/TrEMBL),   A0A8C0QG22 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038499404   ⟸   XM_038643476
- Peptide Label: isoform X2
- UniProtKB: A0A8C0P466 (UniProtKB/TrEMBL),   A0A8P0S899 (UniProtKB/TrEMBL),   A0A8C0QG22 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038499408   ⟸   XM_038643480
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QG22 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038406801   ⟸   XM_038550873
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KBE9 (UniProtKB/TrEMBL),   A0A8C0QG22 (UniProtKB/TrEMBL),   A0A8I3RV22 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038406803   ⟸   XM_038550875
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KBE9 (UniProtKB/TrEMBL),   A0A8C0QG22 (UniProtKB/TrEMBL),   A0A8I3RV22 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038406800   ⟸   XM_038550872
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KBE9 (UniProtKB/TrEMBL),   A0A8C0QG22 (UniProtKB/TrEMBL),   A0A8I3RV22 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038406804   ⟸   XM_038550876
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QG22 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845012575   ⟸   ENSCAFT00845016167


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000002080 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030022293 UniProtKB/TrEMBL
  ENSCAFG00040007238 UniProtKB/TrEMBL
  ENSCAFG00845009185 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000003291.5 UniProtKB/TrEMBL
  ENSCAFT00030040948.1 UniProtKB/TrEMBL
  ENSCAFT00040013464.1 UniProtKB/TrEMBL
  ENSCAFT00845016167 ENTREZGENE
  ENSCAFT00845016167.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.1480.20 UniProtKB/TrEMBL
InterPro Glyco_hydro/deAcase_b/a-brl UniProtKB/TrEMBL
  Glyco_trans_29 UniProtKB/TrEMBL
  GT29-like_sf UniProtKB/TrEMBL
NCBI Gene ST6GAL2 ENTREZGENE
PANTHER BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE UniProtKB/TrEMBL
  BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 2 UniProtKB/TrEMBL
Pfam Glyco_transf_29 UniProtKB/TrEMBL
Superfamily-SCOP SSF88713 UniProtKB/TrEMBL
UniProt A0A8C0KBE9 ENTREZGENE
  A0A8C0P466 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0QG22 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RV22 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0S899 ENTREZGENE
UniProt Secondary A0A8P0S899 UniProtKB/TrEMBL
VGNC ID VGNC:46857 ENTREZGENE