SHISA6 (shisa family member 6) - Rat Genome Database

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Gene: SHISA6 (shisa family member 6) Canis lupus familiaris
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Symbol: SHISA6
Name: shisa family member 6
RGD ID: 12174739
Description: ENCODES a protein that exhibits ionotropic glutamate receptor binding (inferred); PDZ domain binding (inferred); INVOLVED IN excitatory chemical synaptic transmission (inferred); negative regulation of canonical Wnt signaling pathway (inferred); postsynaptic neurotransmitter receptor diffusion trapping (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: shisa homolog 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1535,420,981 - 35,701,654 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl535,424,242 - 35,707,012 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha535,562,452 - 35,839,708 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0535,530,964 - 35,808,773 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl535,530,964 - 35,809,747 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1535,496,683 - 35,775,486 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0535,452,119 - 35,729,778 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0535,635,323 - 35,913,764 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SHISA6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1535,420,981 - 35,701,654 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl535,424,242 - 35,707,012 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha535,562,452 - 35,839,708 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0535,530,964 - 35,808,773 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl535,530,964 - 35,809,747 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1535,496,683 - 35,775,486 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0535,452,119 - 35,729,778 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0535,635,323 - 35,913,764 (+)NCBIUU_Cfam_GSD_1.0
SHISA6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381711,241,213 - 11,564,063 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1711,241,213 - 11,564,063 (+)EnsemblGRCh38hg38GRCh38
GRCh371711,144,530 - 11,467,380 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361711,085,465 - 11,402,921 (+)NCBINCBI36Build 36hg18NCBI36
Celera1711,175,533 - 11,498,055 (+)NCBICelera
Cytogenetic Map17p12NCBI
HuRef1711,046,153 - 11,369,076 (+)NCBIHuRef
CHM1_11711,154,593 - 11,476,588 (+)NCBICHM1_1
T2T-CHM13v2.01711,149,418 - 11,472,179 (+)NCBIT2T-CHM13v2.0
Shisa6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391166,102,551 - 66,418,715 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1166,102,551 - 66,416,790 (-)EnsemblGRCm39 Ensembl
GRCm381166,211,725 - 66,527,984 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1166,211,725 - 66,525,964 (-)EnsemblGRCm38mm10GRCm38
MGSCv371166,025,227 - 66,339,628 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361166,027,924 - 66,342,321 (-)NCBIMGSCv36mm8
Celera1173,147,659 - 73,459,932 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1140.55NCBI
Shisa6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81051,396,806 - 51,691,156 (-)NCBIGRCr8
mRatBN7.21050,897,740 - 51,192,111 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1050,903,333 - 51,192,063 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1055,557,614 - 55,846,501 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01055,047,602 - 55,336,481 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01050,556,088 - 50,843,468 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01052,744,069 - 53,037,853 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1052,749,846 - 53,037,816 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01052,498,328 - 52,791,670 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41052,896,362 - 53,190,809 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1050,092,476 - 50,378,235 (-)NCBICelera
Cytogenetic Map10q24NCBI
Shisa6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554675,707,561 - 5,998,910 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554675,701,521 - 5,998,910 (-)NCBIChiLan1.0ChiLan1.0
SHISA6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21962,180,636 - 62,505,459 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11766,987,394 - 67,312,139 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01740,081,234 - 40,405,916 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11744,831,076 - 45,154,237 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1744,836,825 - 45,154,241 (-)Ensemblpanpan1.1panPan2
Shisa6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560250,498,911 - 50,836,666 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365954,026,604 - 4,304,857 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365953,973,099 - 4,152,706 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SHISA6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11255,757,837 - 56,024,760 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21258,849,892 - 58,898,751 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SHISA6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11610,584,375 - 10,913,012 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605910,348,109 - 10,676,091 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Shisa6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478613,697,330 - 14,001,891 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478613,697,178 - 14,007,891 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SHISA6
3599 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 1 1 1 6 8
Below cutoff 5 5 21 5 6 5 6 6 6 10 6

Sequence


RefSeq Acc Id: ENSCAFT00000027894   ⟹   ENSCAFP00000025941
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl535,673,678 - 35,701,623 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000080191   ⟹   ENSCAFP00000066442
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl535,424,242 - 35,707,012 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845005310   ⟹   ENSCAFP00845004225
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl535,530,964 - 35,809,747 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845005316   ⟹   ENSCAFP00845004231
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl535,530,964 - 35,809,747 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845005322   ⟹   ENSCAFP00845004237
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl535,530,964 - 35,809,747 (+)Ensembl
RefSeq Acc Id: XM_014113231   ⟹   XP_013968706
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1535,420,981 - 35,701,654 (+)NCBI
Dog10K_Boxer_Tasha535,562,452 - 35,839,708 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038475706   ⟹   XP_038331634
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1535,496,683 - 35,775,486 (+)NCBI
RefSeq Acc Id: XM_038536891   ⟹   XP_038392819
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0535,635,323 - 35,913,764 (+)NCBI
RefSeq Acc Id: XM_038601040   ⟹   XP_038456968
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0535,452,119 - 35,729,778 (+)NCBI
RefSeq Acc Id: XM_038665609   ⟹   XP_038521537
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0535,530,964 - 35,808,773 (+)NCBI
RefSeq Acc Id: XP_013968706   ⟸   XM_014113231
- UniProtKB: A0A8C0M1V3 (UniProtKB/TrEMBL),   A0A8I3MNV2 (UniProtKB/TrEMBL),   A0A8P0NIQ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000066442   ⟸   ENSCAFT00000080191
RefSeq Acc Id: ENSCAFP00000025941   ⟸   ENSCAFT00000027894
RefSeq Acc Id: XP_038331634   ⟸   XM_038475706
RefSeq Acc Id: XP_038456968   ⟸   XM_038601040
RefSeq Acc Id: XP_038521537   ⟸   XM_038665609
- UniProtKB: A0A8C0M1V3 (UniProtKB/TrEMBL),   A0A8I3MNV2 (UniProtKB/TrEMBL),   A0A8P0NIQ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038392819   ⟸   XM_038536891
- UniProtKB: A0A8I3MNV2 (UniProtKB/TrEMBL),   A0A8P0NIQ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845004237   ⟸   ENSCAFT00845005322
RefSeq Acc Id: ENSCAFP00845004225   ⟸   ENSCAFT00845005310
RefSeq Acc Id: ENSCAFP00845004231   ⟸   ENSCAFT00845005316


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017598 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030002221 UniProtKB/TrEMBL
  ENSCAFG00040018595 UniProtKB/TrEMBL
  ENSCAFG00845002978 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000027894.5 UniProtKB/TrEMBL
  ENSCAFT00000080191.2 UniProtKB/TrEMBL
  ENSCAFT00000098245.1 UniProtKB/TrEMBL
  ENSCAFT00030004104.1 UniProtKB/TrEMBL
  ENSCAFT00030004126.1 UniProtKB/TrEMBL
  ENSCAFT00040034520.1 UniProtKB/TrEMBL
  ENSCAFT00040034637.1 UniProtKB/TrEMBL
  ENSCAFT00845005310 ENTREZGENE
  ENSCAFT00845005310.1 UniProtKB/TrEMBL
  ENSCAFT00845005316.1 UniProtKB/TrEMBL
  ENSCAFT00845005322.1 UniProtKB/TrEMBL
InterPro Shisa UniProtKB/TrEMBL
NCBI Gene SHISA6 ENTREZGENE
PANTHER PROTEIN SHISA-6 UniProtKB/TrEMBL
  PTHR31774 UniProtKB/TrEMBL
Pfam Shisa UniProtKB/TrEMBL
UniProt A0A8C0M1V3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0Z1L8_CANLF UniProtKB/TrEMBL
  A0A8I3MNV2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MNW3_CANLF UniProtKB/TrEMBL
  A0A8I3N3X4_CANLF UniProtKB/TrEMBL
  A0A8P0NIQ5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PEX7_CANLF UniProtKB/TrEMBL
  A0A8P0TJ87_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:46148 ENTREZGENE