SPATA18 (spermatogenesis associated 18) - Rat Genome Database

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Gene: SPATA18 (spermatogenesis associated 18) Canis lupus familiaris
Analyze
Symbol: SPATA18
Name: spermatogenesis associated 18
RGD ID: 12171727
Description: ENCODES a protein that exhibits cardiolipin binding (inferred); identical protein binding (inferred); molecular condensate scaffold activity (inferred); INVOLVED IN mitochondrial protein catabolic process (inferred); mitophagy by internal vacuole formation (inferred); positive regulation of cardiolipin metabolic process (inferred); ASSOCIATED WITH Breast Neoplasms (ortholog); prostate cancer (ortholog); Prostatic Neoplasms (ortholog); FOUND IN intracellular membraneless organelle (ortholog); mitochondrion (ortholog); sperm flagellum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mitochondria-eating protein; spermatogenesis associated 18 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11344,996,770 - 45,034,327 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1344,996,517 - 45,033,626 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1344,949,296 - 44,987,923 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01345,605,228 - 45,643,831 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1345,605,172 - 45,641,744 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11345,273,144 - 45,311,866 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01344,808,672 - 44,847,257 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01345,685,392 - 45,723,991 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SPATA18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11344,996,770 - 45,034,327 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1344,996,517 - 45,033,626 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1344,949,296 - 44,987,923 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01345,605,228 - 45,643,831 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1345,605,172 - 45,641,744 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11345,273,144 - 45,311,866 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01344,808,672 - 44,847,257 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01345,685,392 - 45,723,991 (+)NCBIUU_Cfam_GSD_1.0
SPATA18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38452,051,304 - 52,097,299 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl452,051,304 - 52,097,299 (+)EnsemblGRCh38hg38GRCh38
GRCh37452,917,470 - 52,963,465 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36452,612,350 - 52,658,215 (+)NCBINCBI36Build 36hg18NCBI36
Celera450,412,632 - 50,458,652 (+)NCBICelera
Cytogenetic Map4q12NCBI
HuRef448,859,053 - 48,905,062 (+)NCBIHuRef
CHM1_1452,953,151 - 52,999,007 (+)NCBICHM1_1
T2T-CHM13v2.0455,537,244 - 55,583,378 (+)NCBIT2T-CHM13v2.0
Spata18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39573,808,723 - 73,836,927 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl573,808,722 - 73,836,855 (+)EnsemblGRCm39 Ensembl
GRCm38573,651,380 - 73,679,584 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl573,651,379 - 73,679,512 (+)EnsemblGRCm38mm10GRCm38
MGSCv37574,042,619 - 74,070,723 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36573,936,670 - 73,958,617 (+)NCBIMGSCv36mm8
Celera570,907,784 - 70,935,895 (+)NCBICelera
Cytogenetic Map5C3.3NCBI
cM Map539.03NCBI
Spata18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81434,885,995 - 34,912,704 (-)NCBIGRCr8
mRatBN7.21434,531,931 - 34,558,671 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1434,531,061 - 34,558,687 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1434,886,631 - 34,918,702 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01436,194,244 - 36,226,317 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01434,679,703 - 34,711,774 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01437,081,529 - 37,108,245 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1437,081,427 - 37,108,341 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01436,904,424 - 36,931,151 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41436,928,255 - 36,954,960 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11436,930,691 - 36,957,395 (-)NCBI
Celera1433,794,494 - 33,821,211 (-)NCBICelera
Cytogenetic Map14p11NCBI
Spata18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544718,401,881 - 18,437,878 (-)NCBIChiLan1.0ChiLan1.0
SPATA18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2377,717,291 - 77,764,860 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1477,921,374 - 77,968,972 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0471,863,549 - 71,911,079 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1478,416,684 - 78,464,191 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl478,416,684 - 78,464,191 (-)Ensemblpanpan1.1panPan2
Spata18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528531,085,300 - 31,119,835 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493648215,178,667 - 15,262,897 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPATA18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl839,163,088 - 39,203,956 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1839,163,001 - 39,206,217 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2841,338,816 - 41,380,595 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SPATA18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1716,342,176 - 16,388,458 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl716,340,607 - 16,387,995 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606617,397,537 - 17,452,952 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spata18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476117,578,125 - 17,642,356 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SPATA18
593 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 19 13 3 5 3 6 29 21 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005628185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038493750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038493751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038556073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038556074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038620005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038620006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038685614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038685615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_532371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_293917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000003181   ⟹   ENSCAFP00000002955
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1344,996,517 - 45,033,626 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000072196   ⟹   ENSCAFP00000048532
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1344,996,517 - 45,033,626 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845019220   ⟹   ENSCAFP00845015016
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1345,605,172 - 45,641,744 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845019265   ⟹   ENSCAFP00845015054
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1345,605,172 - 45,641,744 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845019311   ⟹   ENSCAFP00845015095
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1345,605,172 - 45,637,591 (+)Ensembl
RefSeq Acc Id: XM_005628185   ⟹   XP_005628242
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11344,996,770 - 45,034,327 (+)NCBI
Dog10K_Boxer_Tasha1344,949,296 - 44,987,923 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038493750   ⟹   XP_038349678
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11345,273,153 - 45,311,866 (+)NCBI
RefSeq Acc Id: XM_038493751   ⟹   XP_038349679
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11345,273,144 - 45,311,866 (+)NCBI
RefSeq Acc Id: XM_038556073   ⟹   XP_038412001
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01345,685,402 - 45,723,991 (+)NCBI
RefSeq Acc Id: XM_038556074   ⟹   XP_038412002
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01345,685,392 - 45,723,991 (+)NCBI
RefSeq Acc Id: XM_038620005   ⟹   XP_038475933
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01344,808,681 - 44,847,257 (+)NCBI
RefSeq Acc Id: XM_038620006   ⟹   XP_038475934
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01344,808,672 - 44,847,257 (+)NCBI
RefSeq Acc Id: XM_038685614   ⟹   XP_038541542
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01345,605,238 - 45,643,831 (+)NCBI
RefSeq Acc Id: XM_038685615   ⟹   XP_038541543
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01345,605,228 - 45,643,831 (+)NCBI
RefSeq Acc Id: XM_532371   ⟹   XP_532371
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11344,996,775 - 45,034,327 (+)NCBI
Dog10K_Boxer_Tasha1344,949,305 - 44,987,923 (+)NCBI
Sequence:
RefSeq Acc Id: XP_532371   ⟸   XM_532371
- Peptide Label: isoform X1
- UniProtKB: A0A8C0YXV2 (UniProtKB/TrEMBL),   A0A8I3RY91 (UniProtKB/TrEMBL),   A0A8C0RL76 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005628242   ⟸   XM_005628185
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SK96 (UniProtKB/TrEMBL),   A0A8I3NHI2 (UniProtKB/TrEMBL),   A0A8C0NEG4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000002955   ⟸   ENSCAFT00000003181
Ensembl Acc Id: ENSCAFP00000048532   ⟸   ENSCAFT00000072196
RefSeq Acc Id: XP_038349679   ⟸   XM_038493751
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038349678   ⟸   XM_038493750
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038475934   ⟸   XM_038620006
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038475933   ⟸   XM_038620005
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038541543   ⟸   XM_038685615
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SK96 (UniProtKB/TrEMBL),   A0A8I3NHI2 (UniProtKB/TrEMBL),   A0A8C0NEG4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038541542   ⟸   XM_038685614
- Peptide Label: isoform X1
- UniProtKB: A0A8C0YXV2 (UniProtKB/TrEMBL),   A0A8I3RY91 (UniProtKB/TrEMBL),   A0A8C0RL76 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038412002   ⟸   XM_038556074
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NEG4 (UniProtKB/TrEMBL),   A0A8C0SK96 (UniProtKB/TrEMBL),   A0A8I3NHI2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038412001   ⟸   XM_038556073
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RL76 (UniProtKB/TrEMBL),   A0A8C0YXV2 (UniProtKB/TrEMBL),   A0A8I3RY91 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845015054   ⟸   ENSCAFT00845019265
Ensembl Acc Id: ENSCAFP00845015095   ⟸   ENSCAFT00845019311
Ensembl Acc Id: ENSCAFP00845015016   ⟸   ENSCAFT00845019220
Promoters
RGD ID:13685651
Promoter ID:EPDNEW_C3719
Type:single initiation site
Name:SPATA18_1
Description:spermatogenesis associated 18
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11344,996,876 - 44,996,936EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000002006 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030015718 UniProtKB/TrEMBL
  ENSCAFG00040013750 UniProtKB/TrEMBL
  ENSCAFG00845010886 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000003181.5 UniProtKB/TrEMBL
  ENSCAFT00000072196.2 UniProtKB/TrEMBL
  ENSCAFT00000107179.1 UniProtKB/TrEMBL
  ENSCAFT00030029281.1 UniProtKB/TrEMBL
  ENSCAFT00030029338.1 UniProtKB/TrEMBL
  ENSCAFT00040025543.1 UniProtKB/TrEMBL
  ENSCAFT00040025627.1 UniProtKB/TrEMBL
  ENSCAFT00845019220 ENTREZGENE
  ENSCAFT00845019220.1 UniProtKB/TrEMBL
  ENSCAFT00845019265 ENTREZGENE
  ENSCAFT00845019265.1 UniProtKB/TrEMBL
  ENSCAFT00845019311.1 UniProtKB/TrEMBL
InterPro MIEAP UniProtKB/TrEMBL
  MIEAP_C UniProtKB/TrEMBL
KEGG Report cfa:475141 UniProtKB/TrEMBL
NCBI Gene SPATA18 ENTREZGENE
PANTHER MITOCHONDRIA-EATING PROTEIN UniProtKB/TrEMBL
  PTHR21771 UniProtKB/TrEMBL
Pfam MIEAP UniProtKB/TrEMBL
UniProt A0A8C0NEG4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RL76 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SK96 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0YXV2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NGW5_CANLF UniProtKB/TrEMBL
  A0A8I3NHI2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RY91 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0TQS2_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:46706 ENTREZGENE