FREM2 (FRAS1 related extracellular matrix 2) - Rat Genome Database

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Gene: FREM2 (FRAS1 related extracellular matrix 2) Canis lupus familiaris
Analyze
Symbol: FREM2
Name: FRAS1 related extracellular matrix 2
RGD ID: 12169051
Description: INVOLVED IN cell adhesion (ortholog); embryonic digit morphogenesis (ortholog); eye development (ortholog); ASSOCIATED WITH CAKUT (ortholog); Childhood Schizophrenia (ortholog); congenital diaphragmatic hernia (ortholog); FOUND IN basement membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: FRAS1 related extracellular matrix protein 2; FRAS1-related extracellular matrix protein 2; LOW QUALITY PROTEIN: FRAS1-related extracellular matrix protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1252,097,264 - 2,264,049 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl252,102,849 - 2,264,456 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha252,193,436 - 2,359,496 (-)NCBI
ROS_Cfam_1.0252,194,254 - 2,360,131 (-)NCBI
UMICH_Zoey_3.1252,095,553 - 2,261,726 (-)NCBI
UNSW_CanFamBas_1.0252,089,594 - 2,255,805 (-)NCBI
UU_Cfam_GSD_1.0252,159,315 - 2,325,419 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
FREM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1252,097,264 - 2,264,049 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl252,102,849 - 2,264,456 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha252,193,436 - 2,359,496 (-)NCBI
ROS_Cfam_1.0252,194,254 - 2,360,131 (-)NCBI
UMICH_Zoey_3.1252,095,553 - 2,261,726 (-)NCBI
UNSW_CanFamBas_1.0252,089,594 - 2,255,805 (-)NCBI
UU_Cfam_GSD_1.0252,159,315 - 2,325,419 (-)NCBI
FREM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1338,687,077 - 38,887,131 (+)EnsemblGRCh38hg38GRCh38
GRCh381338,687,041 - 38,887,131 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371339,261,214 - 39,461,268 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361338,159,173 - 38,359,268 (+)NCBINCBI36hg18NCBI36
Build 341338,255,292 - 38,358,072NCBI
Celera1320,314,868 - 20,515,290 (+)NCBI
Cytogenetic Map13q13.3NCBI
HuRef1320,059,603 - 20,259,887 (+)NCBIHuRef
CHM1_11339,228,938 - 39,428,968 (+)NCBICHM1_1
Frem2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39353,421,359 - 53,566,014 (-)NCBIGRCm39mm39
GRCm39 Ensembl353,421,359 - 53,564,776 (-)Ensembl
GRCm38353,513,938 - 53,658,593 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl353,513,938 - 53,657,355 (-)EnsemblGRCm38mm10GRCm38
MGSCv37353,317,860 - 53,461,277 (-)NCBIGRCm37mm9NCBIm37
MGSCv36353,601,867 - 53,745,013 (-)NCBImm8
Celera353,238,829 - 53,381,524 (-)NCBICelera
Cytogenetic Map3CNCBI
cM Map325.24NCBI
Frem2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22137,602,784 - 137,740,785 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl2142,747,501 - 142,885,604 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02142,747,501 - 142,885,604 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02162,430,795 - 162,568,910 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42142,464,169 - 142,604,059 (-)NCBIRGSC3.4rn4RGSC3.4
Celera2132,100,362 - 132,238,927 (-)NCBICelera
Cytogenetic Map2q26NCBI
Frem2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554317,364,937 - 7,541,648 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554317,364,937 - 7,541,419 (-)NCBIChiLan1.0ChiLan1.0
FREM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11338,490,750 - 38,692,200 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1338,490,750 - 38,687,048 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01319,900,324 - 20,103,303 (+)NCBIMhudiblu_PPA_v0panPan3
Frem2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945163,183,741 - 163,353,464 (-)NCBI
SpeTri2.0NW_0049365656,671,578 - 6,837,514 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FREM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1113,959,865 - 14,154,246 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11113,775,267 - 14,116,377 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FREM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1317,121,063 - 17,310,149 (+)NCBI
ChlSab1.1 Ensembl317,129,126 - 17,300,363 (+)Ensembl
Vero_WHO_p1.0NW_02366605726,957,763 - 27,140,436 (-)NCBI
Frem2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249201,683,342 - 1,908,602 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 8 2 2 6
Low 5 5 14 6 6 6 4 6 10 8 4 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000009710   ⟹   ENSCAFP00000009013
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl252,102,849 - 2,263,932 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000083695   ⟹   ENSCAFP00000055318
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl252,102,849 - 2,264,456 (-)Ensembl
RefSeq Acc Id: XM_038434745   ⟹   XP_038290673
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0252,194,254 - 2,360,131 (-)NCBI
RefSeq Acc Id: XM_038458293   ⟹   XP_038314221
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha252,193,436 - 2,359,496 (-)NCBI
RefSeq Acc Id: XM_038509739   ⟹   XP_038365667
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1252,095,553 - 2,261,726 (-)NCBI
RefSeq Acc Id: XM_038573169   ⟹   XP_038429097
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0252,159,315 - 2,325,419 (-)NCBI
RefSeq Acc Id: XM_038637435   ⟹   XP_038493363
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0252,089,594 - 2,255,805 (-)NCBI
RefSeq Acc Id: XM_543127   ⟹   XP_543127
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1252,097,264 - 2,264,033 (-)NCBI
Sequence:
RefSeq Acc Id: XR_295539
RefSeq Status:
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1252,126,867 - 2,264,049 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_543127   ⟸   XM_543127
- Sequence:
RefSeq Acc Id: ENSCAFP00000009013   ⟸   ENSCAFT00000009710
RefSeq Acc Id: ENSCAFP00000055318   ⟸   ENSCAFT00000083695
RefSeq Acc Id: XP_038365667   ⟸   XM_038509739
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038493363   ⟸   XM_038637435
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038290673   ⟸   XM_038434745
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038314221   ⟸   XM_038458293
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038429097   ⟸   XM_038573169
- Peptide Label: isoform X2
Protein Domains
Calx-beta


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000006019 Ensembl, ENTREZGENE
NCBI Gene FREM2 ENTREZGENE
VGNC ID VGNC:40977 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-16 FREM2  FRAS1 related extracellular matrix 2    FRAS1 related extracellular matrix protein 2  Symbol and/or name change 5135510 APPROVED