MIR200A (microRNA mir-200a) - Rat Genome Database

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Gene: MIR200A (microRNA mir-200a) Canis lupus familiaris
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Symbol: MIR200A
Name: microRNA mir-200a
RGD ID: 12167795
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: cfa-mir-200a; microRNA 200a
RGD Orthologs
Human
Mouse
Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1556,369,063 - 56,369,152 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl556,369,061 - 56,369,151 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha556,446,057 - 56,446,146 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0556,571,960 - 56,572,049 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl556,571,958 - 56,572,048 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1556,562,727 - 56,562,816 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0556,454,985 - 56,455,074 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0556,844,978 - 56,845,067 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
RISC complex  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:16381832   PMID:18215311  


Genomics

Comparative Map Data
MIR200A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1556,369,063 - 56,369,152 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl556,369,061 - 56,369,151 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha556,446,057 - 56,446,146 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0556,571,960 - 56,572,049 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl556,571,958 - 56,572,048 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1556,562,727 - 56,562,816 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0556,454,985 - 56,455,074 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0556,844,978 - 56,845,067 (+)NCBIUU_Cfam_GSD_1.0
MIR200A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811,167,863 - 1,167,952 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11,167,863 - 1,167,952 (+)EnsemblGRCh38hg38GRCh38
GRCh3711,103,243 - 1,103,332 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611,093,105 - 1,093,194 (+)NCBINCBI36Build 36hg18NCBI36
Celera11,479,492 - 1,479,581 (-)NCBICelera
Cytogenetic Map1p36.33NCBI
HuRef1374,624 - 374,713 (+)NCBIHuRef
CHM1_111,090,213 - 1,090,302 (+)NCBICHM1_1
T2T-CHM13v2.01596,460 - 596,549 (+)NCBIT2T-CHM13v2.0
Mir200a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394156,139,353 - 156,139,442 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4156,139,353 - 156,139,442 (-)EnsemblGRCm39 Ensembl
GRCm384156,054,896 - 156,054,985 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4156,054,896 - 156,054,985 (-)EnsemblGRCm38mm10GRCm38
MGSCv374155,429,005 - 155,429,094 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera4158,317,292 - 158,317,381 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map487.96NCBI
Mir200a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85171,930,717 - 171,930,805 (-)NCBIGRCr8
mRatBN7.25166,648,494 - 166,648,582 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx5169,352,034 - 169,352,122 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05171,173,456 - 171,173,544 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05171,135,990 - 171,136,078 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05173,489,366 - 173,489,454 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05176,963,388 - 176,963,476 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5164,849,297 - 164,849,385 (-)NCBICelera
Cytogenetic Map5q36NCBI

Variants

.
Variants in MIR200A
1 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system integumental system nervous system reproductive system respiratory system
High
Medium
Low 9 6 11 5
Below cutoff 2 1 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000032750
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl556,369,061 - 56,369,151 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845040339
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl556,571,958 - 56,572,048 (-)Ensembl
RefSeq Acc Id: NR_049455
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1556,369,063 - 56,369,152 (+)NCBI
Dog10K_Boxer_Tasha556,446,057 - 56,446,146 (+)NCBI
ROS_Cfam_1.0556,571,960 - 56,572,049 (+)NCBI
UMICH_Zoey_3.1556,562,727 - 56,562,816 (+)NCBI
UNSW_CanFamBas_1.0556,454,985 - 56,455,074 (+)NCBI
UU_Cfam_GSD_1.0556,844,978 - 56,845,067 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000020643 Ensembl
  ENSCAFG00845022859 Ensembl
miRBase MI0010362 ENTREZGENE
NCBI Gene MIR200A ENTREZGENE
RNAcentral URS000023B77E RNACentral
  URS000075B1D6 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR200A  microRNA mir-200a    microRNA 200a  Symbol and/or name change 5135510 APPROVED