FAM171B (family with sequence similarity 171 member B) - Rat Genome Database

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Gene: FAM171B (family with sequence similarity 171 member B) Canis lupus familiaris
Analyze
Symbol: FAM171B
Name: family with sequence similarity 171 member B
RGD ID: 12167762
Description: ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein FAM171B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13628,934,725 - 28,961,613 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3628,905,006 - 28,961,832 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3628,801,621 - 28,860,554 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03629,128,551 - 29,188,402 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3629,128,551 - 29,188,377 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13629,185,301 - 29,245,138 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03629,120,471 - 29,180,586 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03629,288,267 - 29,348,107 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
synapse  (ISO)

References

Genomics

Comparative Map Data
FAM171B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13628,934,725 - 28,961,613 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3628,905,006 - 28,961,832 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3628,801,621 - 28,860,554 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03629,128,551 - 29,188,402 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3629,128,551 - 29,188,377 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13629,185,301 - 29,245,138 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03629,120,471 - 29,180,586 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03629,288,267 - 29,348,107 (+)NCBIUU_Cfam_GSD_1.0
FAM171B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382186,694,060 - 186,765,959 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2186,694,060 - 186,765,959 (+)EnsemblGRCh38hg38GRCh38
GRCh372187,558,787 - 187,630,686 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362187,267,034 - 187,336,759 (+)NCBINCBI36Build 36hg18NCBI36
Build 342187,384,294 - 187,454,016NCBI
Celera2181,154,411 - 181,224,139 (+)NCBICelera
Cytogenetic Map2q32.1NCBI
HuRef2179,418,653 - 179,488,386 (+)NCBIHuRef
CHM1_12187,564,785 - 187,634,506 (+)NCBICHM1_1
T2T-CHM13v2.02187,183,195 - 187,255,094 (+)NCBIT2T-CHM13v2.0
Fam171b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39283,642,889 - 83,713,878 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl283,642,980 - 83,713,830 (+)EnsemblGRCm39 Ensembl
GRCm38283,812,563 - 83,883,534 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl283,812,636 - 83,883,486 (+)EnsemblGRCm38mm10GRCm38
MGSCv37283,652,885 - 83,721,515 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36283,613,567 - 83,682,197 (+)NCBIMGSCv36mm8
MGSCv36284,723,794 - 84,798,606 (+)NCBIMGSCv36mm8
Celera285,461,824 - 85,536,326 (+)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.33NCBI
Fam171b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8389,337,566 - 89,392,973 (+)NCBIGRCr8
mRatBN7.2368,930,755 - 68,986,113 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl368,930,822 - 68,986,127 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0371,210,048 - 71,265,419 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl371,210,301 - 71,262,615 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0377,735,454 - 77,790,821 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4367,037,142 - 67,092,329 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera368,301,422 - 68,356,773 (+)NCBICelera
Cytogenetic Map3q24NCBI
Fam171b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540311,509,969 - 11,532,616 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540311,512,731 - 11,532,550 (-)NCBIChiLan1.0ChiLan1.0
FAM171B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21389,372,526 - 89,445,428 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B89,387,518 - 89,460,408 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B73,985,579 - 74,058,803 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B191,784,554 - 191,859,440 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B191,786,078 - 191,859,440 (+)Ensemblpanpan1.1panPan2
Fam171b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303146,106,419 - 146,177,805 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650610,660,196 - 10,731,659 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650610,662,513 - 10,731,653 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAM171B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1591,719,511 - 91,798,010 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11591,724,228 - 91,798,012 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215101,733,215 - 101,806,942 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FAM171B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11072,229,785 - 72,301,767 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1072,229,841 - 72,301,902 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040127,204,559 - 127,276,880 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fam171b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248993,157,724 - 3,189,847 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FAM171B
560 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6 12
Low 5 2 15 5 6 5 6 8 10 6
Below cutoff 3 1 1 1 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000046981   ⟹   ENSCAFP00000042521
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3628,905,006 - 28,961,832 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845032638   ⟹   ENSCAFP00845025524
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3629,128,551 - 29,188,377 (+)Ensembl
RefSeq Acc Id: XM_038447272   ⟹   XP_038303200
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03629,128,551 - 29,188,402 (+)NCBI
RefSeq Acc Id: XM_038447273   ⟹   XP_038303201
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03629,131,102 - 29,188,402 (+)NCBI
RefSeq Acc Id: XM_038463400   ⟹   XP_038319328
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3628,801,621 - 28,860,554 (+)NCBI
RefSeq Acc Id: XM_038463401   ⟹   XP_038319329
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3628,803,964 - 28,860,554 (+)NCBI
RefSeq Acc Id: XM_038521349   ⟹   XP_038377277
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13629,185,301 - 29,245,138 (+)NCBI
RefSeq Acc Id: XM_038585062   ⟹   XP_038440990
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03629,288,267 - 29,348,107 (+)NCBI
RefSeq Acc Id: XM_038585063   ⟹   XP_038440991
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03629,290,793 - 29,348,107 (+)NCBI
RefSeq Acc Id: XM_038649475   ⟹   XP_038505403
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03629,120,471 - 29,180,586 (+)NCBI
RefSeq Acc Id: XM_038649476   ⟹   XP_038505404
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03629,123,187 - 29,180,586 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000042521   ⟸   ENSCAFT00000046981
RefSeq Acc Id: XP_038377277   ⟸   XM_038521349
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038505403   ⟸   XM_038649475
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038505404   ⟸   XM_038649476
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038303200   ⟸   XM_038447272
- Peptide Label: isoform X1
- UniProtKB: A0A8C0YSI4 (UniProtKB/TrEMBL),   A0A8I3P3Z4 (UniProtKB/TrEMBL),   A0A8C0K836 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038303201   ⟸   XM_038447273
- Peptide Label: isoform X2
- UniProtKB: A0A8C0MV83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038319328   ⟸   XM_038463400
- Peptide Label: isoform X1
- UniProtKB: A0A8C0YSI4 (UniProtKB/TrEMBL),   A0A8I3P3Z4 (UniProtKB/TrEMBL),   A0A8C0K836 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038319329   ⟸   XM_038463401
- Peptide Label: isoform X2
- UniProtKB: A0A8C0MV83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038440990   ⟸   XM_038585062
- Peptide Label: isoform X1
- UniProtKB: A0A8C0K836 (UniProtKB/TrEMBL),   A0A8C0YSI4 (UniProtKB/TrEMBL),   A0A8I3P3Z4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038440991   ⟸   XM_038585063
- Peptide Label: isoform X2
- UniProtKB: A0A8C0MV83 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845025524   ⟸   ENSCAFT00845032638
Protein Domains
FAM171 C-terminal   FAM171 N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000028669 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030010824 UniProtKB/TrEMBL
  ENSCAFG00040009355 UniProtKB/TrEMBL
  ENSCAFG00845018443 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000046981.3 UniProtKB/TrEMBL
  ENSCAFT00030020008.1 UniProtKB/TrEMBL
  ENSCAFT00040017334.1 UniProtKB/TrEMBL
  ENSCAFT00845032638 ENTREZGENE
  ENSCAFT00845032638.1 UniProtKB/TrEMBL
InterPro FAM171 UniProtKB/TrEMBL
  FAM171_C UniProtKB/TrEMBL
  FAM171_N UniProtKB/TrEMBL
NCBI Gene FAM171B ENTREZGENE
PANTHER PROTEIN FAM171B UniProtKB/TrEMBL
  PTHR31626 UniProtKB/TrEMBL
Pfam FAM171A1-2-B_C UniProtKB/TrEMBL
  UPF0560 UniProtKB/TrEMBL
UniProt A0A8C0K836 ENTREZGENE
  A0A8C0MV83 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0YSI4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P3Z4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:40624 ENTREZGENE