MTERF2 (mitochondrial transcription termination factor 2) - Rat Genome Database

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Gene: MTERF2 (mitochondrial transcription termination factor 2) Canis lupus familiaris
Analyze
Symbol: MTERF2
Name: mitochondrial transcription termination factor 2
RGD ID: 12160645
Description: ENCODES a protein that exhibits DNA binding (inferred); double-stranded DNA binding (inferred); nucleic acid binding (inferred); INVOLVED IN regulation of DNA-templated transcription (inferred); termination of mitochondrial transcription (inferred); ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); FOUND IN mitochondrial matrix (inferred); mitochondrial nucleoid (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcription termination factor 2, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11031,792,889 - 31,794,304 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1031,792,917 - 31,794,074 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1031,765,709 - 31,780,579 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01032,621,587 - 32,636,444 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1032,627,245 - 32,635,702 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11032,357,826 - 32,372,680 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01032,648,303 - 32,663,103 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01032,834,267 - 32,849,133 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MTERF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11031,792,889 - 31,794,304 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1031,792,917 - 31,794,074 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1031,765,709 - 31,780,579 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01032,621,587 - 32,636,444 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1032,627,245 - 32,635,702 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11032,357,826 - 32,372,680 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01032,648,303 - 32,663,103 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01032,834,267 - 32,849,133 (+)NCBIUU_Cfam_GSD_1.0
MTERF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812106,977,277 - 106,987,146 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12106,973,120 - 106,987,163 (-)EnsemblGRCh38hg38GRCh38
GRCh3712107,371,055 - 107,380,924 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612105,895,199 - 105,905,059 (-)NCBINCBI36Build 36hg18NCBI36
Celera12107,036,630 - 107,046,488 (-)NCBICelera
Cytogenetic Map12q23.3NCBI
HuRef12104,431,573 - 104,441,448 (-)NCBIHuRef
CHM1_112107,336,699 - 107,346,574 (-)NCBICHM1_1
T2T-CHM13v2.012106,940,911 - 106,950,780 (-)NCBIT2T-CHM13v2.0
Mterf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391084,951,092 - 84,963,982 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1084,955,297 - 84,963,891 (-)EnsemblGRCm39 Ensembl
GRCm381085,119,433 - 85,128,027 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1085,119,433 - 85,128,027 (-)EnsemblGRCm38mm10GRCm38
MGSCv371084,582,178 - 84,590,772 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361084,549,235 - 84,557,800 (-)NCBIMGSCv36mm8
Celera1087,095,781 - 87,104,375 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1041.63NCBI
Mterf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8720,485,901 - 20,495,979 (+)NCBIGRCr8
mRatBN7.2718,598,202 - 18,608,278 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl718,598,103 - 18,620,684 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx720,559,071 - 20,569,113 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0722,721,769 - 22,731,811 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0722,498,731 - 22,508,773 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0724,638,208 - 24,649,599 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl724,638,208 - 24,648,255 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0724,788,242 - 24,798,742 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4720,713,326 - 20,723,489 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1720,733,596 - 20,743,756 (+)NCBI
Celera715,826,281 - 15,836,295 (+)NCBICelera
Cytogenetic Map7q13NCBI
Mterf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540540,870,215 - 40,871,384 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540540,870,002 - 40,871,433 (-)NCBIChiLan1.0ChiLan1.0
MTERF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210115,033,512 - 115,043,169 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112115,028,022 - 115,039,568 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012104,544,783 - 104,554,675 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112107,938,754 - 107,948,648 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12107,939,021 - 107,940,178 (-)Ensemblpanpan1.1panPan2
Mterf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494514,987,812 - 15,006,137 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364928,005,944 - 8,007,095 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364927,998,229 - 8,007,103 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTERF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl513,367,438 - 13,376,642 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1513,374,243 - 13,376,641 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2513,219,978 - 13,228,224 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MTERF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111102,191,842 - 102,200,719 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11102,190,413 - 102,191,567 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037142,851,536 - 142,865,784 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mterf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247502,539,131 - 2,540,312 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247502,535,015 - 2,555,789 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MTERF2
7 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 9 5 8 6
Low 5 5 13 6 6 6 6 6 7 4 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014117390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038488818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038488819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038488820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038550777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038550778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038550779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038614697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038614698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038614699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038642137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038642138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038642140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038680068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038680069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038680070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000002828   ⟹   ENSCAFP00000002622
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1031,792,917 - 31,794,074 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845021708   ⟹   ENSCAFP00845017070
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1032,627,245 - 32,635,702 (+)Ensembl
RefSeq Acc Id: XM_038488818   ⟹   XP_038344746
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11032,363,459 - 32,372,680 (+)NCBI
RefSeq Acc Id: XM_038488819   ⟹   XP_038344747
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11032,357,826 - 32,372,680 (+)NCBI
RefSeq Acc Id: XM_038488820   ⟹   XP_038344748
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11032,363,458 - 32,372,680 (+)NCBI
RefSeq Acc Id: XM_038550777   ⟹   XP_038406705
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01032,839,902 - 32,849,133 (+)NCBI
RefSeq Acc Id: XM_038550778   ⟹   XP_038406706
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01032,834,267 - 32,849,133 (+)NCBI
RefSeq Acc Id: XM_038550779   ⟹   XP_038406707
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01032,839,901 - 32,849,133 (+)NCBI
RefSeq Acc Id: XM_038614697   ⟹   XP_038470625
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01032,653,892 - 32,663,103 (+)NCBI
RefSeq Acc Id: XM_038614698   ⟹   XP_038470626
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01032,648,303 - 32,663,103 (+)NCBI
RefSeq Acc Id: XM_038614699   ⟹   XP_038470627
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01032,653,891 - 32,663,103 (+)NCBI
RefSeq Acc Id: XM_038642137   ⟹   XP_038498065
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1031,771,354 - 31,780,579 (+)NCBI
RefSeq Acc Id: XM_038642138   ⟹   XP_038498066
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1031,765,709 - 31,780,579 (+)NCBI
RefSeq Acc Id: XM_038642140   ⟹   XP_038498068
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1031,771,353 - 31,780,579 (+)NCBI
RefSeq Acc Id: XM_038680068   ⟹   XP_038535996
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01032,627,221 - 32,636,444 (+)NCBI
RefSeq Acc Id: XM_038680069   ⟹   XP_038535997
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01032,621,587 - 32,636,444 (+)NCBI
RefSeq Acc Id: XM_038680070   ⟹   XP_038535998
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01032,627,220 - 32,636,444 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000002622   ⟸   ENSCAFT00000002828
RefSeq Acc Id: XP_038344747   ⟸   XM_038488819
RefSeq Acc Id: XP_038344748   ⟸   XM_038488820
RefSeq Acc Id: XP_038344746   ⟸   XM_038488818
RefSeq Acc Id: XP_038470626   ⟸   XM_038614698
RefSeq Acc Id: XP_038470627   ⟸   XM_038614699
RefSeq Acc Id: XP_038470625   ⟸   XM_038614697
RefSeq Acc Id: XP_038535997   ⟸   XM_038680069
- UniProtKB: A0A8C0QJ86 (UniProtKB/TrEMBL),   A0A8I3NHY4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038535998   ⟸   XM_038680070
- UniProtKB: A0A8C0QJ86 (UniProtKB/TrEMBL),   A0A8I3NHY4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038535996   ⟸   XM_038680068
- UniProtKB: A0A8C0QJ86 (UniProtKB/TrEMBL),   A0A8I3NHY4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038498066   ⟸   XM_038642138
- UniProtKB: A0A8C0QJ86 (UniProtKB/TrEMBL),   A0A8I3NHY4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038498068   ⟸   XM_038642140
- UniProtKB: A0A8C0QJ86 (UniProtKB/TrEMBL),   A0A8I3NHY4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038498065   ⟸   XM_038642137
- UniProtKB: A0A8C0QJ86 (UniProtKB/TrEMBL),   A0A8I3NHY4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038406706   ⟸   XM_038550778
- UniProtKB: A0A8C0QJ86 (UniProtKB/TrEMBL),   A0A8I3NHY4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038406707   ⟸   XM_038550779
- UniProtKB: A0A8C0QJ86 (UniProtKB/TrEMBL),   A0A8I3NHY4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038406705   ⟸   XM_038550777
- UniProtKB: A0A8C0QJ86 (UniProtKB/TrEMBL),   A0A8I3NHY4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845017070   ⟸   ENSCAFT00845021708


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001799 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030004767 UniProtKB/TrEMBL
  ENSCAFG00040007270 UniProtKB/TrEMBL
  ENSCAFG00845012213 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000002828.2 UniProtKB/TrEMBL
  ENSCAFT00030008744.1 UniProtKB/TrEMBL
  ENSCAFT00040013520.1 UniProtKB/TrEMBL
  ENSCAFT00845021708 ENTREZGENE
  ENSCAFT00845021708.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.70.10 UniProtKB/TrEMBL
InterPro MTERF UniProtKB/TrEMBL
  MTERF_sf UniProtKB/TrEMBL
NCBI Gene MTERF2 ENTREZGENE
PANTHER PTHR15437 UniProtKB/TrEMBL
  TRANSCRIPTION TERMINATION FACTOR 2, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam mTERF UniProtKB/TrEMBL
SMART Mterf UniProtKB/TrEMBL
UniProt A0A8C0QJ86 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NHY4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:43464 ENTREZGENE