GRM2 (glutamate metabotropic receptor 2)

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Gene: GRM2 (glutamate metabotropic receptor 2) Canis lupus familiaris

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Symbol:

GRM2

Name:

glutamate metabotropic receptor 2

RGD ID:

12157297

Description:

ENCODES a protein that exhibits group II metabotropic glutamate receptor activity (ortholog); scaffold protein binding (ortholog); INVOLVED IN behavioral response to nicotine (ortholog); cellular response to stress (ortholog); gene expression (ortholog); ASSOCIATED WITH amphetamine abuse (ortholog); Binge Drinking (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN astrocyte projection (ortholog); axon (ortholog); glutamatergic synapse (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

metabotropic glutamate receptor 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	37,915,178 - 37,926,276 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	37,915,665 - 37,924,296 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	37,895,193 - 37,906,256 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	38,264,331 - 38,275,394 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	38,264,304 - 38,275,372 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	37,627,888 - 37,638,953 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	38,036,604 - 38,047,669 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	38,321,755 - 38,332,818 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amphetamine abuse (ISO)

Binge Drinking (ISO)

Cocaine-Related Disorders (ISO)

heroin dependence (ISO)

schizophrenia (ISO)

substance-induced psychosis (ISO)

temporal lobe epilepsy (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway (IEA)

behavioral response to nicotine (ISO)

cell communication (IEA)

cellular response to stress (IEA,ISO)

G protein-coupled receptor signaling pathway (IEA)

gene expression (IEA,ISO)

glutamate receptor signaling pathway (ISO)

glutamate secretion (ISO)

intracellular glutamate homeostasis (IEA,ISO)

long-term synaptic depression (IEA,ISO)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ISO)

presynaptic modulation of chemical synaptic transmission (IEA)

regulation of dopamine secretion (ISO)

regulation of glutamate secretion (ISO)

regulation of response to drug (ISO)

response to cocaine (ISO)

signaling (IEA)

Cellular Component

astrocyte projection (ISO)

axon (ISO)

glutamatergic synapse (IEA,ISO)

membrane (IEA)

neuron projection (IEA)

plasma membrane (IEA)

postsynaptic membrane (IEA,ISO)

presynapse (IEA)

presynaptic membrane (ISO)

Molecular Function

calcium channel regulator activity (IEA)

G protein-coupled receptor activity (IEA)

group II metabotropic glutamate receptor activity (IEA,ISO)

protein binding (ISO)

scaffold protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

GRM2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	37,915,178 - 37,926,276 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	37,915,665 - 37,924,296 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	37,895,193 - 37,906,256 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	38,264,331 - 38,275,394 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	38,264,304 - 38,275,372 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	37,627,888 - 37,638,953 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	38,036,604 - 38,047,669 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	38,321,755 - 38,332,818 (-)	NCBI		UU_Cfam_GSD_1.0

GRM2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	51,707,068 - 51,718,613 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	51,707,068 - 51,718,613 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	51,741,084 - 51,752,629 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	51,718,004 - 51,727,669 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	51,718,037 - 51,727,168	NCBI
Celera	3	51,718,848 - 51,731,506 (+)	NCBI		Celera
Cytogenetic Map	3	p21.2	NCBI
HuRef	3	51,802,839 - 51,816,142 (+)	NCBI		HuRef
CHM1_1	3	51,693,893 - 51,705,447 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	51,738,578 - 51,751,605 (+)	NCBI		T2T-CHM13v2.0

Grm2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	106,521,733 - 106,533,308 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	106,520,294 - 106,533,281 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	106,644,534 - 106,656,109 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	106,643,095 - 106,656,082 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	106,546,865 - 106,558,440 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	106,546,755 - 106,558,434 (-)	NCBI		MGSCv36	mm8
Celera	9	106,265,562 - 106,277,130 (-)	NCBI		Celera
Cytogenetic Map	9	F1	NCBI
cM Map	9	57.98	NCBI

Grm2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	116,158,810 - 116,171,857 (-)	NCBI		GRCr8
mRatBN7.2	8	107,280,099 - 107,293,159 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	107,280,099 - 107,293,146 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	112,903,031 - 112,916,129 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	111,102,213 - 111,115,309 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	108,944,991 - 108,958,085 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	115,344,999 - 115,358,628 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	115,344,999 - 115,358,046 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	114,705,123 - 114,718,193 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	111,837,086 - 111,850,133 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	111,857,819 - 111,869,581 (-)	NCBI
Celera	8	106,592,051 - 106,605,096 (-)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

Grm2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955532	3,309,028 - 3,320,966 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955532	3,309,034 - 3,320,954 (+)	NCBI	ChiLan1.0	ChiLan1.0

GRM2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	51,694,559 - 51,707,434 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	51,699,333 - 51,712,208 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	51,639,792 - 51,652,779 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	52,873,144 - 52,884,401 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	52,873,144 - 52,884,395 (+)	Ensembl	panpan1.1		panPan2

Grm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	66,281,725 - 66,293,182 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936529	3,042,248 - 3,053,673 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936529	3,042,220 - 3,053,670 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GRM2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	33,926,804 - 33,938,269 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	33,924,303 - 33,938,279 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	37,130,553 - 37,141,351 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GRM2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	13,044,974 - 13,056,469 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	13,046,641 - 13,056,453 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	153,898,374 - 153,910,372 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Grm2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	5,419,896 - 5,431,361 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	5,419,892 - 5,431,268 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in GRM2
55 total Variants

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_022406662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038427610	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038427611	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038427612	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038455922	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038455923	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038503313	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038503314	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038503315	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038566296	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038566297	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038566298	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038630453	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038630454	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038630455	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_541867	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002616794	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005297930	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005312832	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005341117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005374909	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005408905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000236	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000058	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000016044 ⟹ ENSCAFP00000014839

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	20	37,915,665 - 37,924,296 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000086394 ⟹ ENSCAFP00000055767

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	20	37,915,665 - 37,924,296 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845033348 ⟹ ENSCAFP00845026102

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	20	38,264,304 - 38,275,372 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845033401 ⟹ ENSCAFP00845026146

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	20	38,264,304 - 38,275,372 (-)	Ensembl

RefSeq Acc Id:

XM_038427610 ⟹ XP_038283538

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	20	38,264,331 - 38,275,394 (-)	NCBI

RefSeq Acc Id:

XM_038427611 ⟹ XP_038283539

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	20	38,264,331 - 38,275,394 (-)	NCBI

RefSeq Acc Id:

XM_038427612 ⟹ XP_038283540

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	20	38,265,711 - 38,275,394 (-)	NCBI

RefSeq Acc Id:

XM_038455922 ⟹ XP_038311850

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	20	37,895,193 - 37,906,256 (-)	NCBI

RefSeq Acc Id:

XM_038455923 ⟹ XP_038311851

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	20	37,896,573 - 37,906,256 (-)	NCBI

RefSeq Acc Id:

XM_038503313 ⟹ XP_038359241

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	20	37,627,888 - 37,638,953 (-)	NCBI

RefSeq Acc Id:

XM_038503314 ⟹ XP_038359242

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	20	37,627,888 - 37,638,953 (-)	NCBI

RefSeq Acc Id:

XM_038503315 ⟹ XP_038359243

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	20	37,629,268 - 37,638,953 (-)	NCBI

RefSeq Acc Id:

XM_038566296 ⟹ XP_038422224

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	20	38,321,755 - 38,332,818 (-)	NCBI

RefSeq Acc Id:

XM_038566297 ⟹ XP_038422225

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	20	38,321,755 - 38,332,818 (-)	NCBI

RefSeq Acc Id:

XM_038566298 ⟹ XP_038422226

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	20	38,323,135 - 38,332,818 (-)	NCBI

RefSeq Acc Id:

XM_038630453 ⟹ XP_038486381

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	20	38,036,604 - 38,047,669 (-)	NCBI

RefSeq Acc Id:

XM_038630454 ⟹ XP_038486382

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	20	38,036,604 - 38,047,669 (-)	NCBI

RefSeq Acc Id:

XM_038630455 ⟹ XP_038486383

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	20	38,037,984 - 38,047,669 (-)	NCBI

RefSeq Acc Id:

XM_541867 ⟹ XP_541867

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	20	37,915,178 - 37,926,276 (-)	NCBI
Dog10K_Boxer_Tasha	20	37,895,193 - 37,906,256 (-)	NCBI

Sequence:

show sequence

GATTGAAAGCGGCCGGGCGAGCTGGCGGGCGGAGAGCGCAGAGCTGCTGAGCGAGGGAGCAAGC
CACTGAGCGAGAGCTGGAACCCTGCGCCCCCGGCTCCTCTCCGTTTCTCTCCGCGCCGGAGTCG
GGCGCGCCAGGAGCTGGGTCCCTTCTAAATTCTCTTCCTGCCTGTCCTTTCCTGGTTCCTGCTT
CCTCCTTTCTTTGCCTTTGCTGCTTCTATCCTCATCCCCCGGAGGCCCAGGTCTGCTGGACCCA
TCCATCCCCTTTGGGACTATGGGATCACTGCTTGGGCTCCTGGCACTGCTGCTGCTATGGGGTG
CTGTGGCTGAGGGCCCTGCCAAGAAGGTGCTGACCCTGGAGGGGGACCTGGTCCTGGGTGGGCT
GTTTCCAGTACACCAGAAGGGTGGCCCAGCAGAGGAGTGTGGGCCTGTCAATGAGCATCGTGGC
ATCCAGCGCCTGGAGGCCATGCTTTTTGCACTGGACCGCATCAACCGTGACCCACACCTGCTGC
CAGGCGTGCGCCTGGGCGCGCATATTCTCGACAGCTGCTCCAAGGACACACATGCCCTGGAGCA
GGCACTCGACTTCGTGCGTGCCTCGCTTAGCCGTGGTGCCGATGGCTCACGCCACATCTGCCCC
GATGGCTCGTATGCCACCCACGGTGATGCTCCCACTGCCATCACTGGTGTCATTGGCGGCTCCT
ACAGCGATGTCTCCATCCAGGTGGCCAACCTCCTGCGGCTATTTCAGATCCCACAGATTAGCTA
TGCCTCCACCAGCGCCAAGCTGAGTGACAAGTCCCGCTATGACTACTTTGCCCGCACAGTGCCC
CCCGACTTCTTCCAAGCCAAAGCCATGGCTGAGATTCTCCGCTTCTTCAACTGGACCTATGTGT
CCACTGTGGCATCTGAGGGTGACTATGGCGAGACAGGCATCGAAGCCTTTGAGCTAGAGGCCCG
TGCCCGCAACATCTGTGTGGCCACCTCGGAGAAAGTGGGCCGTGCCATGAGCCGCGCAGCTTTT
GAGGGTGTGGTGCGAGCCCTGCTGCAGAAGCCCAGTGCCCGTGTGGCTGTCCTGTTCACCCGTT
CTGAGGATGCCCGCGAGCTCCTCGCGGCTACCCAGCGCCTCAATGCCAGCTTCACCTGGGTGGC
CAGCGATGGCTGGGGGGCCCTGGAGAGTGTGGTGGCAGGCAGTGAGAGGGCTGCTGAGGGTGCC
ATCACTATTGAGCTGGCCTCCTATCCCATCAGTGACTTTGCCTCCTACTTCCGGAGCCTGGACC
CCTGGAACAACAGCCGGAACCCCTGGTTCCGTGAGTTCTGGGAGCAGAGGTTCCACTGTAGCTT
CCGGCGGCGAGATTGCGCAGCCCACTCACTACAGGCCGTGCCTTTTGAGCAAGAGTCCAAGATC
ATGTTTGTCGTTAATGCAGTGTATGCCATGGCCCATGCGCTGCACAACATGCACCGAGCCCTCT
GCCCCAACACCACCCAACTCTGTGATGCAATGCGGCCTGTCAACGGACGCCGGCTCTACAAGGA
CTTCGTACTCAACGTCAAATTTGATGCCCCCTTCCGCCCGGCTGACACGCACAGTGAGGTCCGC
TTTGACCGCTTTGGTGATGGCATTGGTCGCTACAACATCTTCACCTATTTGCGGGCAGGGAGTG
GGCGCTATCGCTACCAGAAGGTAGGCTACTGGGCAGAAGGCCTAACCCTGGATACCAGCCTCAT
CCCATGGGCCTCGCCCTCGGCCAGCTCCCTGCCCGCCTCTCGCTGCAGTGAGCCCTGTCTCCAG
AATGAAGTGAAGAGCGTGCAGCCAGGGGAGGTCTGCTGCTGGCTCTGCATCCCCTGCCAGCCCT
ACGAGTACCGGCTGGACGAATTCACTTGTGCTGACTGTGGCCTGGGTTACTGGCCCAATGCCAG
CCTGACCGGCTGCTTTGAGCTGCCCCAGGAGTACATCCGCTGGGGTGATGCCTGGGCTGTGGGA
CCTGTCACCATCGCCTGTCTAGGTGCCCTGGCGACCCTCTTTGTGCTGGGTGTCTTTGTGCGGC
ACAATGCCACACCAGTGGTCAAGGCCTCTGGACGGGAGCTCTGCTACATCCTGTTGGGCGGTGT
CTTCCTCTGCTACTGCATGACCTTCATCTTCATTGCCAAGCCATCCACGGTGGTGTGTACCTTA
CGGCGCCTTGGTCTGGGCACCGCCTTCTCTGTCTGCTACTCAGCTCTGCTCACCAAGACCAACC
GCATTGCACGCATCTTTGGTGGGGCCCGGGAGGGAGCCCAGCGACCACGCTTCATCAGTCCTGC
CTCGCAGGTGGCCATCTGCCTGGCACTTATCTCGGGCCAGCTGCTCATTGTAGCTGCCTGGCTG
GTGGTGGAAGCACCAGGCACGGGCAAGGAGACAGCCCCAGAGCGGCGGGAGGTGGTAACATTGC
GCTGCAACCATCGAGATGCAAGCATGCTGGGTTCACTGGCCTACAACGTGCTCCTCATCGCACT
CTGCACACTCTATGCCTTCAAGACCCGCAAGTGCCCTGAGAACTTCAATGAGGCCAAATTCATA
GGCTTTACCATGTACACCACTTGCATCATCTGGCTGGCCTTCCTGCCCATCTTCTATGTCACCT
CCAGTGACTACCGGGTACAGACCACCACCATGTGCGTATCAGTCAGCCTCAGTGGCTCTGTGGT
GCTCGGCTGTCTCTTTGCACCCAAGTTGCACATCATCCTTTTCCAGCCACAGAAGAATGTGGTC
AGCCACCGTGCGCCCACCAGCCGCTTCAGCAGCGCCGCCACCAGGGCCAGCTCCAGCCTCGGCC
AAGGATCTGGCTCCCAGTTTGTCCCCACCGTTTGCAACGGCCGTGAGGTGGTAGATTCAACAAC
ATCGTCACTTTGAGGACCCTGCTTTCCTCCCTGACACAGCTGCTCCCTGGAACCTGGTGCAGAC
CCGCATACAGGGCCAGGAAGAAGTCAGCTGGAGCACTGCAATAATGCCACTCCCATGCCCATCC
CCAAAACCCACTTACTCCAACCCTTCAGAGTCAGAAGTCAGGGTCCTTGGCCCAGCAGCCTCTG
CAACAGCCACCAACTGTCCTTGCAGCGTGTCCCCTCCTTGCTAGGCCCAGGACTCCGAAGGAAG
CAAGCCAGGGTCTACTCTGCCCTGGAACAGGATGGCTGAGGACTGTGGGCCCCAATCCCCAATC
AGCAAAGGTGCTTCCAGCCCCACCTCTCCTTCCTTCTAGGGCCTTTTTAATTTTTTACATAAGT
TCTTCTGGGATGGGGAGGGGGGTTTTGTGGGGGCCATCCCTTCCTTGCATAGTAGTTTGTCCTG
TGGTTTATTTTGTATTATCTGTAAATAAAGTGTCTTTATTTAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XR_005297930

Type:

NON-CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	20	38,265,170 - 38,275,394 (-)	NCBI

RefSeq Acc Id:

XR_005312832

Type:

NON-CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	20	37,896,032 - 37,906,256 (-)	NCBI

RefSeq Acc Id:

XR_005341117

Type:

NON-CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	20	37,628,727 - 37,638,953 (-)	NCBI

RefSeq Acc Id:

XR_005374909

Type:

NON-CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	20	38,322,594 - 38,332,818 (-)	NCBI

RefSeq Acc Id:

XR_005408905

Type:

NON-CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	20	38,037,443 - 38,047,669 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_038283538	(Get FASTA)	NCBI Sequence Viewer
	XP_038283539	(Get FASTA)	NCBI Sequence Viewer
	XP_038283540	(Get FASTA)	NCBI Sequence Viewer
	XP_038311850	(Get FASTA)	NCBI Sequence Viewer
	XP_038311851	(Get FASTA)	NCBI Sequence Viewer
	XP_038359241	(Get FASTA)	NCBI Sequence Viewer
	XP_038359242	(Get FASTA)	NCBI Sequence Viewer
	XP_038359243	(Get FASTA)	NCBI Sequence Viewer
	XP_038422224	(Get FASTA)	NCBI Sequence Viewer
	XP_038422225	(Get FASTA)	NCBI Sequence Viewer
	XP_038422226	(Get FASTA)	NCBI Sequence Viewer
	XP_038486381	(Get FASTA)	NCBI Sequence Viewer
	XP_038486382	(Get FASTA)	NCBI Sequence Viewer
	XP_038486383	(Get FASTA)	NCBI Sequence Viewer
	XP_541867	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000014839.3
	ENSCAFP00000055767.1
	ENSCAFP00030015638.1
	ENSCAFP00030015684.1
	ENSCAFP00040037437.1
	ENSCAFP00040037456.1
	ENSCAFP00845026102
	ENSCAFP00845026102.1
	ENSCAFP00845026146.1

RefSeq Acc Id:	XP_541867 ⟸ XM_541867
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0MRA0 (UniProtKB/TrEMBL), A0A8C0LE78 (UniProtKB/TrEMBL), A0A8I3P4V6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGSLLGLLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEECGPVNEHRGIQRLEA MLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYAT HGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQA KAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRA LLQKPSARVAVLFTRSEDARELLAATQRLNASFTWVASDGWGALESVVAGSERAAEGAITIELA SYPISDFASYFRSLDPWNNSRNPWFREFWEQRFHCSFRRRDCAAHSLQAVPFEQESKIMFVVNA VYAMAHALHNMHRALCPNTTQLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHSEVRFDRFGD GIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWASPSASSLPASRCSEPCLQNEVKSV QPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIAC LGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTVVCTLRRLGLG TAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVAAWLVVEAPG TGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYT TCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRAPT SRFSSAATRASSSLGQGSGSQFVPTVCNGREVVDSTTSSL hide sequence

Ensembl Acc Id:

ENSCAFP00000055767 ⟸ ENSCAFT00000086394

Ensembl Acc Id:

ENSCAFP00000014839 ⟸ ENSCAFT00000016044

RefSeq Acc Id:	XP_038359242 ⟸ XM_038503314
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038359241 ⟸ XM_038503313
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038359243 ⟸ XM_038503315
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038486382 ⟸ XM_038630454
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038486381 ⟸ XM_038630453
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038486383 ⟸ XM_038630455
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038283539 ⟸ XM_038427611
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0MRA0 (UniProtKB/TrEMBL), A0A8C0LE78 (UniProtKB/TrEMBL), A0A8I3P4V6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038283538 ⟸ XM_038427610
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038283540 ⟸ XM_038427612
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038311850 ⟸ XM_038455922
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038311851 ⟸ XM_038455923
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038422225 ⟸ XM_038566297
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0LE78 (UniProtKB/TrEMBL), A0A8C0MRA0 (UniProtKB/TrEMBL), A0A8I3P4V6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038422224 ⟸ XM_038566296
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038422226 ⟸ XM_038566298
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSCAFP00845026146 ⟸ ENSCAFT00845033401

Ensembl Acc Id:

ENSCAFP00845026102 ⟸ ENSCAFT00845033348

Protein Domains

G-protein coupled receptors family 3 profile

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000010091	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030009676	UniProtKB/TrEMBL
	ENSCAFG00040023095	UniProtKB/TrEMBL
	ENSCAFG00845018876	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000016044.5	UniProtKB/TrEMBL
	ENSCAFT00000086394.2	UniProtKB/TrEMBL
	ENSCAFT00030017907.1	UniProtKB/TrEMBL
	ENSCAFT00030017956.1	UniProtKB/TrEMBL
	ENSCAFT00040042909.1	UniProtKB/TrEMBL
	ENSCAFT00040042934.1	UniProtKB/TrEMBL
	ENSCAFT00845033348	ENTREZGENE
	ENSCAFT00845033348.1	UniProtKB/TrEMBL
	ENSCAFT00845033401.1	UniProtKB/TrEMBL
Gene3D-CATH	2.10.50.30	UniProtKB/TrEMBL
	3.40.50.2300	UniProtKB/TrEMBL
InterPro	ANF_lig-bd_rcpt	UniProtKB/TrEMBL
	GPCR_3	UniProtKB/TrEMBL
	GPCR_3_9-Cys_dom	UniProtKB/TrEMBL
	GPCR_3_9-Cys_sf	UniProtKB/TrEMBL
	GPCR_3_C	UniProtKB/TrEMBL
	GPCR_3_CS	UniProtKB/TrEMBL
	GPCR_3_mtglu_rcpt	UniProtKB/TrEMBL
	GPCR_3_mtglu_rcpt_2	UniProtKB/TrEMBL
	mGluR	UniProtKB/TrEMBL
	Peripla_BP_I	UniProtKB/TrEMBL
NCBI Gene	GRM2	ENTREZGENE
PANTHER	METABOTROPIC GLUTAMATE RECEPTOR	UniProtKB/TrEMBL
	METABOTROPIC GLUTAMATE RECEPTOR 2	UniProtKB/TrEMBL
Pfam	7tm_3	UniProtKB/TrEMBL
	ANF_receptor	UniProtKB/TrEMBL
	NCD3G	UniProtKB/TrEMBL
PRINTS	GPCRMGR	UniProtKB/TrEMBL
	MTABOTROPC2R	UniProtKB/TrEMBL
	MTABOTROPICR	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F3_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F3_2	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F3_3	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F3_4	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53822	UniProtKB/TrEMBL
UniProt	A0A8C0LE78	ENTREZGENE
	A0A8C0MRA0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0MY68_CANLF	UniProtKB/TrEMBL
	A0A8I3P4V6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3P824_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:41509	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD