RNGTT (RNA guanylyltransferase and 5'-phosphatase) - Rat Genome Database
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Gene: RNGTT (RNA guanylyltransferase and 5'-phosphatase) Canis lupus familiaris
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Symbol: RNGTT
Name: RNA guanylyltransferase and 5'-phosphatase
RGD ID: 12156793
Description: ENCODES a protein that exhibits RNA guanylyltransferase activity (ortholog); INVOLVED IN RNA processing (ortholog); PARTICIPATES IN 5'-end pre-mRNA capping pathway; RNA polymerase II transcription elongation pathway; FOUND IN integral component of membrane (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: mRNA-capping enzyme
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1247,946,561 - 48,275,969 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11247,944,600 - 48,306,789 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
RNGTT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1247,946,561 - 48,275,969 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11247,944,600 - 48,306,789 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
RNGTT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl688,609,897 - 88,963,618 (-)EnsemblGRCh38hg38GRCh38
GRCh38688,609,897 - 88,963,618 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37689,319,988 - 89,673,440 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36689,376,708 - 89,730,067 (-)NCBINCBI36hg18NCBI36
Build 34689,376,717 - 89,730,023NCBI
Celera689,737,906 - 90,091,236 (-)NCBI
Cytogenetic Map6q15NCBI
HuRef686,535,387 - 86,889,057 (-)NCBIHuRef
CHM1_1689,417,380 - 89,771,218 (-)NCBICHM1_1
Rngtt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39433,310,300 - 33,502,614 (+)NCBIGRCm39mm39
GRCm38433,310,300 - 33,502,614 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl433,310,311 - 33,502,614 (+)EnsemblGRCm38mm10GRCm38
MGSCv37433,397,286 - 33,589,585 (+)NCBIGRCm37mm9NCBIm37
MGSCv36433,639,043 - 33,831,223 (+)NCBImm8
Celera433,062,022 - 33,255,229 (+)NCBICelera
Cytogenetic Map4A5NCBI
Rngtt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0548,561,325 - 48,779,214 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl548,561,339 - 48,779,207 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0553,143,335 - 53,362,344 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4549,605,150 - 49,811,502 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1549,605,435 - 49,809,750 (+)NCBI
Celera546,464,963 - 46,671,822 (+)NCBICelera
Cytogenetic Map5q21NCBI
Rngtt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541115,486,303 - 15,766,864 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541115,486,532 - 15,766,880 (-)NCBIChiLan1.0ChiLan1.0
RNGTT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1689,761,712 - 90,118,184 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl689,761,712 - 90,118,184 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0686,490,725 - 86,841,421 (-)NCBIMhudiblu_PPA_v0panPan3
Rngtt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365103,186,552 - 3,405,862 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNGTT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl156,852,863 - 57,061,972 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1156,852,864 - 57,061,985 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2163,571,851 - 63,750,208 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RNGTT
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11313,053,741 - 13,386,479 (-)NCBI
ChlSab1.1 Ensembl1313,053,405 - 13,386,481 (-)Ensembl
Rngtt
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247995,225,293 - 5,553,957 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 11 7 8 8 1
Low 5 5 11 6 6 6 6 6 5 2 5
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022426344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022426346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038492414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038554708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038554709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038554710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038618579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038618580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038618581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038684137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038684138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038684139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_539035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005368010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005402357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005430738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005435779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000004955   ⟹   ENSCAFP00000004594
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1247,946,561 - 48,275,463 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000045102   ⟹   ENSCAFP00000036583
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1247,946,561 - 48,275,463 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000060387   ⟹   ENSCAFP00000057692
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1247,946,561 - 48,275,969 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000075552   ⟹   ENSCAFP00000044016
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1247,946,561 - 48,275,463 (-)Ensembl
RefSeq Acc Id: XM_014118140   ⟹   XP_013973615
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11247,993,114 - 48,275,513 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022426343   ⟹   XP_022282051
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11247,944,600 - 48,275,512 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022426344   ⟹   XP_022282052
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11247,944,600 - 48,306,789 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022426346   ⟹   XP_022282054
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11247,948,767 - 48,275,513 (-)NCBI
Sequence:
RefSeq Acc Id: XM_539035   ⟹   XP_539035
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11247,944,600 - 48,275,511 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_539035   ⟸   XM_539035
- Peptide Label: isoform X1
- UniProtKB: E2R9G2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013973615   ⟸   XM_014118140
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_022282052   ⟸   XM_022426344
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_022282051   ⟸   XM_022426343
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_022282054   ⟸   XM_022426346
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSCAFP00000057692   ⟸   ENSCAFT00000060387
RefSeq Acc Id: ENSCAFP00000036583   ⟸   ENSCAFT00000045102
RefSeq Acc Id: ENSCAFP00000004594   ⟸   ENSCAFT00000004955
RefSeq Acc Id: ENSCAFP00000044016   ⟸   ENSCAFT00000075552
Protein Domains
TYR_PHOSPHATASE_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000003089 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000004594 ENTREZGENE, UniProtKB/TrEMBL
  ENSCAFP00000036583 UniProtKB/TrEMBL
  ENSCAFP00000044016 UniProtKB/TrEMBL
  ENSCAFP00000057692 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000004955 UniProtKB/TrEMBL
  ENSCAFT00000045102 UniProtKB/TrEMBL
  ENSCAFT00000060387 UniProtKB/TrEMBL
  ENSCAFT00000075552 UniProtKB/TrEMBL
Gene3D-CATH 3.90.190.10 UniProtKB/TrEMBL
InterPro Dual-sp_phosphatase_cat-dom UniProtKB/TrEMBL
  mRNA_cap_enz_bifunc UniProtKB/TrEMBL
  mRNA_cap_enzyme UniProtKB/TrEMBL
  mRNA_cap_enzyme_C UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/TrEMBL
NCBI Gene RNGTT ENTREZGENE
Pfam DSPc UniProtKB/TrEMBL
  mRNA_cap_C UniProtKB/TrEMBL
  mRNA_cap_enzyme UniProtKB/TrEMBL
PIRSF mRNA_capping_HCE UniProtKB/TrEMBL
PROSITE TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF50249 UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt A0A5F4BSV3_CANLF UniProtKB/TrEMBL
  A0A5F4CW60_CANLF UniProtKB/TrEMBL
  E2R9G2 ENTREZGENE, UniProtKB/TrEMBL
  J9NTU7_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:45679 ENTREZGENE