PEX19 (peroxisomal biogenesis factor 19) - Rat Genome Database

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Gene: PEX19 (peroxisomal biogenesis factor 19) Canis lupus familiaris
Analyze
Symbol: PEX19
Name: peroxisomal biogenesis factor 19
RGD ID: 12154022
Description: ENCODES a protein that exhibits ATPase binding (inferred); peroxisome membrane class-1 targeting sequence binding (inferred); protein carrier chaperone (inferred); INVOLVED IN peroxisome membrane biogenesis (ortholog); ASSOCIATED WITH autoimmune interstitial lung, joint, and kidney disease (ortholog); familial hemiplegic migraine (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN brush border membrane (ortholog); membrane (ortholog); nucleus (ortholog); INTERACTS WITH mocetinostat
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13821,939,054 - 21,945,281 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3821,939,018 - 21,944,602 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3822,012,447 - 22,018,702 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03822,055,478 - 22,061,737 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3822,055,526 - 22,067,139 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13821,960,482 - 21,966,737 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03822,356,710 - 22,362,956 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,766,324 - 22,772,586 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
mocetinostat  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PEX19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13821,939,054 - 21,945,281 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3821,939,018 - 21,944,602 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3822,012,447 - 22,018,702 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03822,055,478 - 22,061,737 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3822,055,526 - 22,067,139 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13821,960,482 - 21,966,737 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03822,356,710 - 22,362,956 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,766,324 - 22,772,586 (+)NCBIUU_Cfam_GSD_1.0
PEX19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381160,276,807 - 160,285,151 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1160,276,807 - 160,286,348 (-)EnsemblGRCh38hg38GRCh38
GRCh371160,246,597 - 160,254,941 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361158,513,226 - 158,521,555 (-)NCBINCBI36Build 36hg18NCBI36
Build 341157,059,674 - 157,068,004NCBI
Celera1133,315,362 - 133,323,704 (-)NCBICelera
Cytogenetic Map1q23.2NCBI
HuRef1131,603,239 - 131,611,581 (-)NCBIHuRef
CHM1_11161,641,944 - 161,650,286 (-)NCBICHM1_1
T2T-CHM13v2.01159,413,883 - 159,422,227 (-)NCBIT2T-CHM13v2.0
Pex19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391171,954,322 - 171,964,064 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1171,954,322 - 171,964,060 (+)EnsemblGRCm39 Ensembl
GRCm381172,126,755 - 172,136,497 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1172,126,755 - 172,136,493 (+)EnsemblGRCm38mm10GRCm38
MGSCv371174,056,886 - 174,066,628 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361173,963,447 - 173,972,455 (+)NCBIMGSCv36mm8
Celera1174,981,963 - 174,991,751 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.54NCBI
Pex19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81387,124,654 - 87,141,170 (+)NCBIGRCr8
mRatBN7.21384,592,277 - 84,608,793 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1384,592,312 - 84,608,608 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1387,095,642 - 87,112,114 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01388,495,900 - 88,512,372 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01385,680,449 - 85,697,145 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01390,514,324 - 90,530,825 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1871,607,340 - 71,614,980 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1390,514,336 - 90,530,349 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01395,035,461 - 95,051,834 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41388,122,462 - 88,139,003 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1384,203,953 - 84,220,188 (+)NCBICelera
Cytogenetic Map13q24NCBI
Pex19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546812,049,043 - 12,057,364 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546812,049,043 - 12,057,751 (-)NCBIChiLan1.0ChiLan1.0
PEX19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2189,566,863 - 89,573,569 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1189,306,840 - 89,315,224 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01135,630,788 - 135,639,126 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11139,551,681 - 139,559,957 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1139,551,681 - 139,559,954 (-)Ensemblpanpan1.1panPan2
Pex19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050586,395,854 - 6,403,436 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936740351,045 - 359,033 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936740351,089 - 357,657 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PEX19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl490,195,852 - 90,205,215 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1490,196,986 - 90,213,308 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2498,087,493 - 98,095,580 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PEX19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1203,663,375 - 3,672,113 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl203,663,001 - 3,669,404 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660382,721,016 - 2,729,663 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pex19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624794975,889 - 982,721 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624794976,885 - 982,723 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PEX19
83 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000019883   ⟹   ENSCAFP00000018441
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3821,939,018 - 21,944,602 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000083182   ⟹   ENSCAFP00000060838
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3821,939,018 - 21,944,602 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845054333   ⟹   ENSCAFP00845042692
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3822,055,526 - 22,067,139 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845054337   ⟹   ENSCAFP00845042695
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3822,055,526 - 22,062,761 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845054348   ⟹   ENSCAFP00845042702
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3822,055,526 - 22,061,729 (+)Ensembl
RefSeq Acc Id: XM_022415349   ⟹   XP_022271057
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13821,939,097 - 21,945,281 (+)NCBI
Dog10K_Boxer_Tasha3822,012,472 - 22,018,702 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038448682   ⟹   XP_038304610
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03822,055,478 - 22,061,737 (+)NCBI
RefSeq Acc Id: XM_038448683   ⟹   XP_038304611
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03822,055,504 - 22,061,737 (+)NCBI
RefSeq Acc Id: XM_038522571   ⟹   XP_038378499
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13821,960,482 - 21,966,737 (+)NCBI
RefSeq Acc Id: XM_038522572   ⟹   XP_038378500
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13821,960,507 - 21,966,737 (+)NCBI
RefSeq Acc Id: XM_038586351   ⟹   XP_038442279
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03822,766,324 - 22,772,586 (+)NCBI
RefSeq Acc Id: XM_038586352   ⟹   XP_038442280
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03822,766,349 - 22,772,586 (+)NCBI
RefSeq Acc Id: XM_038650771   ⟹   XP_038506699
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03822,356,710 - 22,362,956 (+)NCBI
RefSeq Acc Id: XM_038650772   ⟹   XP_038506700
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03822,356,735 - 22,362,956 (+)NCBI
RefSeq Acc Id: XM_536130   ⟹   XP_536130
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13821,939,054 - 21,945,281 (+)NCBI
Dog10K_Boxer_Tasha3822,012,447 - 22,018,702 (+)NCBI
Sequence:
RefSeq Acc Id: XP_536130   ⟸   XM_536130
- Peptide Label: isoform X1
- UniProtKB: A0A8C0SWZ8 (UniProtKB/TrEMBL),   A0A8C0L6M6 (UniProtKB/TrEMBL),   A0A8I3S7P7 (UniProtKB/TrEMBL),   A0A8I3QNW4 (UniProtKB/TrEMBL),   A0A8P0PK49 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022271057   ⟸   XM_022415349
- Peptide Label: isoform X2
- UniProtKB: A0A8C0L1D2 (UniProtKB/TrEMBL),   A0A8I3Q4P4 (UniProtKB/TrEMBL),   A0A8I3QNW4 (UniProtKB/TrEMBL),   A0A8P0PK49 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000018441   ⟸   ENSCAFT00000019883
Ensembl Acc Id: ENSCAFP00000060838   ⟸   ENSCAFT00000083182
RefSeq Acc Id: XP_038378499   ⟸   XM_038522571
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038378500   ⟸   XM_038522572
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038506699   ⟸   XM_038650771
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038506700   ⟸   XM_038650772
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038304610   ⟸   XM_038448682
- Peptide Label: isoform X1
- UniProtKB: A0A8C0SWZ8 (UniProtKB/TrEMBL),   A0A8C0L6M6 (UniProtKB/TrEMBL),   A0A8I3S7P7 (UniProtKB/TrEMBL),   A0A8I3QNW4 (UniProtKB/TrEMBL),   A0A8P0PK49 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038304611   ⟸   XM_038448683
- Peptide Label: isoform X2
- UniProtKB: A0A8C0L1D2 (UniProtKB/TrEMBL),   A0A8I3Q4P4 (UniProtKB/TrEMBL),   A0A8I3QNW4 (UniProtKB/TrEMBL),   A0A8P0PK49 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038442279   ⟸   XM_038586351
- Peptide Label: isoform X1
- UniProtKB: A0A8C0L6M6 (UniProtKB/TrEMBL),   A0A8C0SWZ8 (UniProtKB/TrEMBL),   A0A8I3QNW4 (UniProtKB/TrEMBL),   A0A8I3S7P7 (UniProtKB/TrEMBL),   A0A8P0PK49 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038442280   ⟸   XM_038586352
- Peptide Label: isoform X2
- UniProtKB: A0A8C0L1D2 (UniProtKB/TrEMBL),   A0A8I3Q4P4 (UniProtKB/TrEMBL),   A0A8I3QNW4 (UniProtKB/TrEMBL),   A0A8P0PK49 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845042702   ⟸   ENSCAFT00845054348
Ensembl Acc Id: ENSCAFP00845042695   ⟸   ENSCAFT00845054337
Ensembl Acc Id: ENSCAFP00845042692   ⟸   ENSCAFT00845054333

Promoters
RGD ID:13689229
Promoter ID:EPDNEW_C7296
Type:single initiation site
Name:PEX19_1
Description:peroxisomal biogenesis factor 19
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13821,939,073 - 21,939,133EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000012510 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030016645 UniProtKB/TrEMBL
  ENSCAFG00040016530 UniProtKB/TrEMBL
  ENSCAFG00845030621 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000019883.6 UniProtKB/TrEMBL
  ENSCAFT00000083182.2 UniProtKB/TrEMBL
  ENSCAFT00000095594.1 UniProtKB/TrEMBL
  ENSCAFT00030030688.1 UniProtKB/TrEMBL
  ENSCAFT00040030583.1 UniProtKB/TrEMBL
  ENSCAFT00845054333.1 UniProtKB/TrEMBL
  ENSCAFT00845054337 ENTREZGENE
  ENSCAFT00845054337.1 UniProtKB/TrEMBL
  ENSCAFT00845054348 ENTREZGENE
  ENSCAFT00845054348.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.900 UniProtKB/TrEMBL
InterPro Pex19 UniProtKB/TrEMBL
  Pex19_C_sf UniProtKB/TrEMBL
NCBI Gene PEX19 ENTREZGENE
PANTHER PEROXISOMAL BIOGENESIS FACTOR 19 UniProtKB/TrEMBL
  PTHR12774 UniProtKB/TrEMBL
Pfam Pex19 UniProtKB/TrEMBL
UniProt A0A8C0L1D2 ENTREZGENE
  A0A8C0L6M6 ENTREZGENE
  A0A8C0SWZ8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q4P4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3QNW4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S7P7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NEG0_CANLF UniProtKB/TrEMBL
  A0A8P0P9V4_CANLF UniProtKB/TrEMBL
  A0A8P0PK49 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:44432 ENTREZGENE