MAFB (MAF bZIP transcription factor B) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: MAFB (MAF bZIP transcription factor B) Canis lupus familiaris
Analyze
Symbol: MAFB
Name: MAF bZIP transcription factor B
RGD ID: 12147171
Description: ENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN brain segmentation (ortholog); inner ear morphogenesis (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH BROWN SYNDROME (ortholog); cleft lip (ortholog); COVID-19 (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcription factor MafB
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12428,769,904 - 28,772,519 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2428,770,944 - 28,774,948 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2428,416,065 - 28,419,157 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02429,474,707 - 29,477,799 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12428,744,730 - 28,747,822 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02428,848,428 - 28,851,520 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02429,343,869 - 29,346,962 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MAFB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12428,769,904 - 28,772,519 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2428,770,944 - 28,774,948 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2428,416,065 - 28,419,157 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02429,474,707 - 29,477,799 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12428,744,730 - 28,747,822 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02428,848,428 - 28,851,520 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02429,343,869 - 29,346,962 (-)NCBIUU_Cfam_GSD_1.0
MAFB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382040,685,848 - 40,689,236 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2040,685,848 - 40,689,236 (-)EnsemblGRCh38hg38GRCh38
GRCh372039,314,488 - 39,317,876 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362038,747,929 - 38,751,290 (-)NCBINCBI36Build 36hg18NCBI36
Build 342038,747,928 - 38,751,290NCBI
Celera2036,024,991 - 36,028,352 (-)NCBICelera
Cytogenetic Map20q12NCBI
HuRef2036,052,429 - 36,055,822 (-)NCBIHuRef
CHM1_12039,218,912 - 39,222,304 (-)NCBICHM1_1
T2T-CHM13v2.02042,417,334 - 42,420,722 (-)NCBIT2T-CHM13v2.0
Mafb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392160,205,597 - 160,208,985 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2160,205,623 - 160,208,985 (-)EnsemblGRCm39 Ensembl
GRCm382160,363,677 - 160,367,065 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2160,363,703 - 160,367,065 (-)EnsemblGRCm38mm10GRCm38
MGSCv372160,189,413 - 160,192,801 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362160,055,202 - 160,058,455 (-)NCBIMGSCv36mm8
Celera2166,294,850 - 166,298,242 (-)NCBICelera
Cytogenetic Map2H2NCBI
cM Map280.92NCBI
Mafb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83169,417,890 - 169,419,810 (-)NCBIGRCr8
mRatBN7.23148,998,111 - 149,000,031 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3148,998,122 - 149,000,031 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3152,813,737 - 152,815,657 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03161,313,129 - 161,315,049 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03159,051,829 - 159,053,749 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03156,338,993 - 156,340,913 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3156,339,004 - 156,340,913 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03162,572,668 - 162,574,588 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43151,116,831 - 151,118,751 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13151,022,739 - 151,024,660 (-)NCBI
Celera3147,675,895 - 147,677,815 (-)NCBICelera
RH 3.4 Map31369.7RGD
Cytogenetic Map3q42NCBI
Mafb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544516,219,675 - 16,222,913 (+)NCBIChiLan1.0ChiLan1.0
MAFB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22146,425,575 - 46,429,119 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12046,418,674 - 46,422,133 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02037,023,988 - 37,027,446 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12038,125,705 - 38,128,724 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2038,127,722 - 38,128,693 (-)Ensemblpanpan1.1panPan2
Mafb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640177,738,940 - 177,742,271 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365611,007,647 - 1,008,618 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365611,007,273 - 1,010,548 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAFB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1743,404,927 - 43,411,739 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11743,408,390 - 43,411,782 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21748,698,403 - 48,701,189 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAFB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1223,092,547 - 23,097,721 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl223,094,713 - 23,095,684 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605071,901,067 - 71,904,494 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mafb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249191,339,228 - 1,340,208 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249191,337,269 - 1,340,607 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MAFB
22 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000038508   ⟹   ENSCAFP00000034242
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2428,770,944 - 28,774,948 (-)Ensembl
RefSeq Acc Id: XM_005635059   ⟹   XP_005635116
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12428,769,904 - 28,772,519 (-)NCBI
Dog10K_Boxer_Tasha2428,416,065 - 28,419,157 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038432869   ⟹   XP_038288797
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02429,474,707 - 29,477,799 (-)NCBI
RefSeq Acc Id: XM_038509635   ⟹   XP_038365563
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12428,744,730 - 28,747,822 (-)NCBI
RefSeq Acc Id: XM_038571375   ⟹   XP_038427303
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02429,343,869 - 29,346,962 (-)NCBI
RefSeq Acc Id: XM_038635573   ⟹   XP_038491501
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02428,848,428 - 28,851,520 (-)NCBI
RefSeq Acc Id: XP_005635116   ⟸   XM_005635059
- UniProtKB: A0A8C0KI15 (UniProtKB/TrEMBL),   A0A8C0T5Z4 (UniProtKB/TrEMBL),   A0A8I3Q7X9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000034242   ⟸   ENSCAFT00000038508
RefSeq Acc Id: XP_038365563   ⟸   XM_038509635
RefSeq Acc Id: XP_038491501   ⟸   XM_038635573
RefSeq Acc Id: XP_038288797   ⟸   XM_038432869
- UniProtKB: A0A8C0KI15 (UniProtKB/TrEMBL),   A0A8C0T5Z4 (UniProtKB/TrEMBL),   A0A8I3Q7X9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038427303   ⟸   XM_038571375
- UniProtKB: A0A8C0T5Z4 (UniProtKB/TrEMBL),   A0A8I3Q7X9 (UniProtKB/TrEMBL),   A0A8C0KI15 (UniProtKB/TrEMBL)
Protein Domains
bZIP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000024903 Ensembl
  ENSCAFG00000055493 UniProtKB/TrEMBL
  ENSCAFG00040020038 UniProtKB/TrEMBL
  ENSCAFG00845029935 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000108221.1 UniProtKB/TrEMBL
  ENSCAFT00040037031.1 UniProtKB/TrEMBL
  ENSCAFT00845053021.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
InterPro bZIP UniProtKB/TrEMBL
  bZIP_Maf UniProtKB/TrEMBL
  bZIP_sf UniProtKB/TrEMBL
  Maf_TF_N UniProtKB/TrEMBL
  TF_DNA-bd_sf UniProtKB/TrEMBL
  Transcription_factor_Maf_fam UniProtKB/TrEMBL
NCBI Gene MAFB ENTREZGENE
PANTHER TRANSCRIPTION FACTOR MAF UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR MAFB UniProtKB/TrEMBL
Pfam bZIP_Maf UniProtKB/TrEMBL
  Maf_N UniProtKB/TrEMBL
PROSITE BZIP UniProtKB/TrEMBL
SMART BRLZ UniProtKB/TrEMBL
Superfamily-SCOP A DNA-binding domain in eukaryotic transcription factors UniProtKB/TrEMBL
  Leucine zipper domain UniProtKB/TrEMBL
UniProt A0A8C0KI15 ENTREZGENE
  A0A8C0T5Z4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q7X9 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:54653 ENTREZGENE