SYT2 (synaptotagmin 2) - Rat Genome Database

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Gene: SYT2 (synaptotagmin 2) Canis lupus familiaris
Analyze
Symbol: SYT2
Name: synaptotagmin 2
RGD ID: 12146581
Description: ENCODES a protein that exhibits inositol 1,3,4,5 tetrakisphosphate binding (ortholog); INVOLVED IN calcium-dependent activation of synaptic vesicle fusion (ortholog); ASSOCIATED WITH axonal neuropathy (ortholog); congenital myasthenic syndrome (ortholog); congenital myasthenic syndrome 7 (ortholog); FOUND IN neuromuscular junction (ortholog); synaptic vesicle membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: synaptotagmin II; synaptotagmin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.17497,387 - 509,338 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl7497,394 - 502,952 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha7478,659 - 557,321 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.07433,590 - 512,581 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl7433,409 - 512,622 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.17422,285 - 501,206 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.07531,125 - 609,898 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.07554,413 - 633,358 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SYT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.17497,387 - 509,338 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl7497,394 - 502,952 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha7478,659 - 557,321 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.07433,590 - 512,581 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl7433,409 - 512,622 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.17422,285 - 501,206 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.07531,125 - 609,898 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.07554,413 - 633,358 (+)NCBIUU_Cfam_GSD_1.0
SYT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381202,590,596 - 202,710,454 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1202,590,596 - 202,710,454 (-)EnsemblGRCh38hg38GRCh38
GRCh371202,559,724 - 202,679,582 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361200,831,511 - 200,946,168 (-)NCBINCBI36Build 36hg18NCBI36
Build 341199,296,544 - 199,411,202NCBI
Celera1175,686,865 - 175,807,438 (-)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1173,725,569 - 173,845,371 (-)NCBIHuRef
CHM1_11203,981,971 - 204,101,776 (-)NCBICHM1_1
T2T-CHM13v2.01201,852,402 - 201,972,645 (-)NCBIT2T-CHM13v2.0
Syt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391134,574,319 - 134,680,887 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1134,574,415 - 134,690,331 (+)EnsemblGRCm39 Ensembl
GRCm381134,646,534 - 134,753,149 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1134,646,677 - 134,762,593 (+)EnsemblGRCm38mm10GRCm38
MGSCv371136,543,258 - 136,645,994 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361136,463,092 - 136,565,828 (+)NCBIMGSCv36mm8
Celera1137,257,554 - 137,373,520 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.24NCBI
Syt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81348,639,634 - 48,749,814 (+)NCBIGRCr8
mRatBN7.21346,088,046 - 46,197,976 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1346,185,282 - 46,193,859 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1348,791,632 - 48,800,091 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01350,079,700 - 50,088,159 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01347,345,602 - 47,354,226 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01351,569,248 - 51,577,824 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1351,534,025 - 51,578,052 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01356,621,954 - 56,630,530 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41347,690,518 - 47,699,094 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11347,704,560 - 47,713,137 (+)NCBI
Celera1346,512,022 - 46,520,623 (+)NCBICelera
Cytogenetic Map13q13NCBI
Syt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540638,643,911 - 38,743,222 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540638,638,192 - 38,743,077 (-)NCBIChiLan1.0ChiLan1.0
SYT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2146,671,196 - 46,785,814 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1146,637,844 - 46,758,650 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01178,187,872 - 178,308,522 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11182,484,225 - 182,605,743 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1182,490,401 - 182,538,123 (-)Ensemblpanpan1.1panPan2
Syt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934472,642,164 - 72,749,746 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365671,941,639 - 1,984,428 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365671,941,651 - 1,984,422 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SYT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1024,638,704 - 24,669,846 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11024,638,645 - 24,727,198 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21029,086,244 - 29,094,379 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SYT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12526,702,627 - 26,821,108 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2526,808,007 - 26,817,314 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605527,480,660 - 27,602,721 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Syt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248078,160,431 - 8,196,916 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248078,103,665 - 8,201,567 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SYT2
106 total Variants

Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014114942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038480531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038480532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038541858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038541859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038560579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038560580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038605989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038605990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038670697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038670698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000093001   ⟹   ENSCAFP00000056726
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl7497,394 - 502,952 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845026951   ⟹   ENSCAFP00845021216
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl7433,409 - 512,622 (+)Ensembl
RefSeq Acc Id: XM_038480531   ⟹   XP_038336459
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.17474,634 - 501,206 (+)NCBI
RefSeq Acc Id: XM_038480532   ⟹   XP_038336460
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.17422,285 - 501,206 (+)NCBI
RefSeq Acc Id: XM_038541858   ⟹   XP_038397786
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.07606,776 - 633,358 (+)NCBI
RefSeq Acc Id: XM_038541859   ⟹   XP_038397787
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.07554,413 - 633,358 (+)NCBI
RefSeq Acc Id: XM_038560579   ⟹   XP_038416507
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha7530,769 - 557,321 (+)NCBI
RefSeq Acc Id: XM_038560580   ⟹   XP_038416508
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha7478,659 - 557,321 (+)NCBI
RefSeq Acc Id: XM_038605989   ⟹   XP_038461917
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.07583,360 - 609,898 (+)NCBI
RefSeq Acc Id: XM_038605990   ⟹   XP_038461918
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.07531,125 - 609,898 (+)NCBI
RefSeq Acc Id: XM_038670697   ⟹   XP_038526625
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.07485,976 - 512,581 (+)NCBI
RefSeq Acc Id: XM_038670698   ⟹   XP_038526626
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.07433,590 - 512,581 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000056726   ⟸   ENSCAFT00000093001
RefSeq Acc Id: XP_038336460   ⟸   XM_038480532
RefSeq Acc Id: XP_038336459   ⟸   XM_038480531
RefSeq Acc Id: XP_038461918   ⟸   XM_038605990
RefSeq Acc Id: XP_038461917   ⟸   XM_038605989
RefSeq Acc Id: XP_038526626   ⟸   XM_038670698
- UniProtKB: A0A8C0Q4X4 (UniProtKB/TrEMBL),   A0A8C0R291 (UniProtKB/TrEMBL),   A0A8I3P087 (UniProtKB/TrEMBL),   A0A8P0PKG1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038526625   ⟸   XM_038670697
- UniProtKB: A0A8C0Q4X4 (UniProtKB/TrEMBL),   A0A8C0R291 (UniProtKB/TrEMBL),   A0A8I3P087 (UniProtKB/TrEMBL),   A0A8P0PKG1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038416508   ⟸   XM_038560580
- UniProtKB: A0A8C0Q4X4 (UniProtKB/TrEMBL),   A0A8C0R291 (UniProtKB/TrEMBL),   A0A8I3P087 (UniProtKB/TrEMBL),   A0A8P0PKG1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038416507   ⟸   XM_038560579
- UniProtKB: A0A8C0Q4X4 (UniProtKB/TrEMBL),   A0A8C0R291 (UniProtKB/TrEMBL),   A0A8I3P087 (UniProtKB/TrEMBL),   A0A8P0PKG1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038397787   ⟸   XM_038541859
- UniProtKB: A0A8C0Q4X4 (UniProtKB/TrEMBL),   A0A8C0R291 (UniProtKB/TrEMBL),   A0A8I3P087 (UniProtKB/TrEMBL),   A0A8P0PKG1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038397786   ⟸   XM_038541858
- UniProtKB: A0A8C0Q4X4 (UniProtKB/TrEMBL),   A0A8C0R291 (UniProtKB/TrEMBL),   A0A8I3P087 (UniProtKB/TrEMBL),   A0A8P0PKG1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845021216   ⟸   ENSCAFT00845026951
Protein Domains
C2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000044241 Ensembl
  ENSCAFG00000058609 UniProtKB/TrEMBL
  ENSCAFG00040003115 UniProtKB/TrEMBL
  ENSCAFG00845015072 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000105119.1 UniProtKB/TrEMBL
  ENSCAFT00040005918.1 UniProtKB/TrEMBL
  ENSCAFT00040005938.1 UniProtKB/TrEMBL
  ENSCAFT00845026951 ENTREZGENE
  ENSCAFT00845026951.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  Synaptotagmin UniProtKB/TrEMBL
NCBI Gene SYT2 ENTREZGENE
PANTHER PTHR10024:SF223 UniProtKB/TrEMBL
  SYNAPTOTAGMIN UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/TrEMBL
PRINTS C2DOMAIN UniProtKB/TrEMBL
  SYNAPTOTAGMN UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/TrEMBL
SMART SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
UniProt A0A8C0Q323_CANLF UniProtKB/TrEMBL
  A0A8C0Q4X4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0R291 ENTREZGENE
  A0A8I3P087 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PKG1 ENTREZGENE, UniProtKB/TrEMBL