Gene: MYH9 (myosin heavy chain 9) Canis lupus familiaris |
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 Analyze |
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Symbol: |
MYH9 |
Name: |
myosin heavy chain 9 |
Description: |
ENCODES a protein that exhibits actin filament binding (ortholog); ATPase activity (ortholog); integrin binding (ortholog); INVOLVED IN vesicle targeting; actin cytoskeleton reorganization (ortholog); actin filament-based movement (ortholog); PARTICIPATES IN myocarditis pathway; ASSOCIATED WITH AIDS-Associated Nephropathy (ortholog); Albuminuria (ortholog); Alport syndrome (ortholog); FOUND IN exocytic vesicle; actin cytoskeleton (ortholog); actomyosin contractile ring (ortholog) |
Type: |
protein-coding
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RefSeq Status: |
PROVISIONAL |
Also known as: |
myosin heavy chain, non-muscle IIa; myosin, heavy polypeptide 9, non-muscle; myosin-9; NMMHC II-a; NMMHC-IIA; non-muscle myosin heavy chain IIa |
Orthologs: |
Species |
Gene symbol and name |
Data Source |
Assertion derived from |
less info ...
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Orthologs 1 |
Homo sapiens (human): |
MYH9 (myosin heavy chain 9) |
HGNC |
Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Treefam |
Mus musculus (house mouse): |
Myh9 (myosin, heavy polypeptide 9, non-muscle) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
Rattus norvegicus (Norway rat): |
Myh9 (myosin, heavy chain 9) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
Chinchilla lanigera (long-tailed chinchilla): |
Myh9 (myosin heavy chain 9) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
Pan paniscus (bonobo/pygmy chimpanzee): |
MYH9 (myosin heavy chain 9) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
Ictidomys tridecemlineatus (thirteen-lined ground squirrel): |
Myh9 (myosin heavy chain 9) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
Sus scrofa (pig): |
MYH9 (myosin heavy chain 9) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
Other homologs 2 |
Homo sapiens (human): |
MYH13 (myosin heavy chain 13) |
HGNC |
OrthoMCL |
Homo sapiens (human): |
MYH14 (myosin heavy chain 14) |
HGNC |
OrthoMCL |
Homo sapiens (human): |
MYH7B (myosin heavy chain 7B) |
HGNC |
OrthoMCL |
Homo sapiens (human): |
MYH4 (myosin heavy chain 4) |
HGNC |
OrthoMCL |
Homo sapiens (human): |
MYH2 (myosin heavy chain 2) |
HGNC |
OrthoMCL |
Homo sapiens (human): |
MYH15 (myosin heavy chain 15) |
HGNC |
OrthoMCL |
Homo sapiens (human): |
MYH1 (myosin heavy chain 1) |
HGNC |
OrthoMCL |
Homo sapiens (human): |
MYH10 (myosin heavy chain 10) |
HGNC |
OrthoMCL |
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Latest Assembly: |
CanFam3.1 - Dog CanFam3.1 Assembly |
NCBI Annotation Information: |
Annotation category: partial on reference assembly |
Position: |
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JBrowse: |
View Region in Genome Browser (JBrowse)
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Model |
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 Disease Annotations
RGD Manual Annotations
AIDS-Associated Nephropathy | | ISS | RGD:8944101 | 9068941 | protein:decreased expression:glomerulus | RGD | PMID:22313957, REF_RGD_ID:6903274 | Albuminuria | | ISS | RGD:8944101 | 9068941 | associated with hypertension, DNA:SNPs: : | RGD | PMID:19153477, REF_RGD_ID:6903241 | autosomal dominant Alport syndrome | | ISS | RGD:8944101 | 9068941 | DNA:missense mutation:exon:4270G>C, D1424H (human) | RGD | PMID:12500226, REF_RGD_ID:6902925 | Carotid Artery Injuries | | ISS | RGD:8944101 | 9068941 | protein:increased expression:carotid artery: | RGD | PMID:11003588, REF_RGD_ID:11533926 | chronic kidney disease | no_association | ISS | RGD:8944101 | 9068941 | | RGD | PMID:22956460, REF_RGD_ID:12798515 | end stage renal failure | | ISS | RGD:8944101 | 9068941 | associated with hypertension, glomerulosclerosis, focal segmental, DNA:SNPs: :rs4821480, rs2032487, rs4821481(human) | RGD | PMID:18794854, REF_RGD_ID:6903237 | end stage renal failure | | ISS | RGD:8944101 | 9068941 | associated with diabetes mellitus more ... | RGD | PMID:19567477, REF_RGD_ID:6903238 | end stage renal failure | | ISS | RGD:8944101 | 9068941 | DNA:SNPs:multiple: | RGD | PMID:20144966, REF_RGD_ID:6903243 | end stage renal failure | | ISS | RGD:8944101 | 9068941 | associated with diabetes mellitus, type 2, DNA:SNPs: : | RGD | PMID:21968013, REF_RGD_ID:6903256 | end stage renal failure | | ISS | RGD:8944101 | 9068941 | associated with hypertension, DNA:polymorphisms:multiple: | RGD | PMID:19177153, REF_RGD_ID:6903239 | focal segmental glomerulosclerosis | | ISS | RGD:8944101 | 9068941 | | RGD | PMID:21402784, REF_RGD_ID:6903254 | human immunodeficiency virus infectious disease | | ISS | RGD:8944101 | 9068941 | protein:decreased expression:glomerulus | RGD | PMID:22313957, REF_RGD_ID:6903274 | metabolic acidosis | | ISS | RGD:8944101 | 9068941 | protein:increased expression:brush border membrane | RGD | PMID:22357915, REF_RGD_ID:7243154 | MYH-9 related disease | | IEA | | 12801476 | May-Hegglin anomaly | OMIA | PMID:21554370 | MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | DNA:mutation:cds:p.R702C(mouse) | RGD | PMID:23976996, REF_RGD_ID:11533924 | MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | DNA:missense mutations:exons:multiple | RGD | PMID:11752022, REF_RGD_ID:6903235 | MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | protein:increased expression:neutrophil: | RGD | PMID:16806139, REF_RGD_ID:11532766 | MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | DNA:missense mutation:exon:p.R702H(human) | RGD | PMID:11935325, REF_RGD_ID:6902926 | Nonsyndromic Sensorineural Hearing Loss | | ISS | RGD:8944101 | 9068941 | DNA:mutation:cds:p.R705H(human) | RGD | PMID:11023810, REF_RGD_ID:11533925 | orofacial cleft | | ISS | RGD:8944101 | 9068941 | DNA:SNPs: :rs3752462, rs2009930 (human) | RGD | PMID:17337617, REF_RGD_ID:12798514 | orofacial cleft | | ISS | RGD:8944101 | 9068941 | DNA:SNP, haplotype: :rs7078 (human) | RGD | PMID:19320731, REF_RGD_ID:12798512 | orofacial cleft | | ISS | RGD:8944101 | 9068941 | DNA:SNPs | RGD | PMID:18716610, REF_RGD_ID:12798509 | orofacial cleft | | ISS | RGD:8944101 | 9068941 | DNA:SNPs: :rs2269529, rs3752462, rs16996652 (human) | RGD | PMID:19891592, REF_RGD_ID:12798511 | proteinuria | disease_progression | ISS | RGD:8944101 | 9068941 | associated with Epstein syndrome, Fechtner syndrome, DNA:missense mutation:exon:p.R702H, R702C(human) | RGD | PMID:20200500, REF_RGD_ID:6903242 | proteinuria | | ISS | RGD:8944101 | 9068941 | associated with anemia, sickle cell:DNA:SNPs: : | RGD | PMID:21910715, REF_RGD_ID:6903258 | sensorineural hearing loss | disease_progression | ISS | RGD:8944101 | 9068941 | associated with MYH9-Related Disorders, DNA:mutations:cds: | RGD | PMID:26226608, REF_RGD_ID:11533922 | thrombocytopenia | | ISS | RGD:8944101 | 9068941 | May-Hegglin anomaly, OMIM:155100, DNA:point mutation:exon:R1933X | RGD | PMID:10973259, REF_RGD_ID:1600553 | |
Imported Annotations - ClinVar
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autosomal dominant nonsyndromic deafness 17 | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Deafness, autosomal dominant 17 | ClinVar | PMID:24033266, PMID:25741868 |
autosomal dominant nonsyndromic deafness 17 | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Deafness, autosomal dominant nonsyndromic sensorineural 17 | ClinVar | PMID:16818291 more ... |
autosomal dominant nonsyndromic deafness 17 | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Deafness, autosomal dominant 17 | ClinVar | PMID:11752022 more ... |
autosomal dominant nonsyndromic deafness 17 | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: DEAFNESS, AUTOSOMAL DOMINANT 17 | ClinVar | PMID:11023810 more ... |
autosomal dominant nonsyndromic deafness 17 | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Deafness, autosomal dominant 17 | ClinVar | PMID:24033266 more ... |
autosomal recessive nonsyndromic deafness | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Autosomal recessive non-syndromic sensorineural deafness type DFNB | ClinVar | |
Capillary Hemangioma, Infantile | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Hemangioma, capillary infantile | ClinVar | |
Epistaxis | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Epistaxis | ClinVar | PMID:25741868 |
Giant Platelet Syndrome with Thrombocytopenia | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Giant platelet syndrome with thrombocytopenia | ClinVar | PMID:10973259, PMID:25741868 |
Giant Platelet Syndrome with Thrombocytopenia | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Giant platelet syndrome with thrombocytopenia | ClinVar | PMID:11590545 more ... |
Giant Platelet Syndrome with Thrombocytopenia | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Giant platelet syndrome with thrombocytopenia | ClinVar | PMID:24033266 more ... |
Giant Platelet Syndrome with Thrombocytopenia | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Giant platelet syndrome with thrombocytopenia | ClinVar | PMID:12792306, PMID:19450438 |
Giant Platelet Syndrome with Thrombocytopenia | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Giant platelet syndrome with thrombocytopenia | ClinVar | PMID:15613099 |
Giant Platelet Syndrome with Thrombocytopenia | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Giant platelet syndrome with thrombocytopenia | ClinVar | PMID:10973259, PMID:11093280 |
Giant Platelet Syndrome with Thrombocytopenia | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Giant platelet syndrome with thrombocytopenia | ClinVar | PMID:10973260, PMID:12792306 |
Giant Platelet Syndrome with Thrombocytopenia | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Giant platelet syndrome with thrombocytopenia | ClinVar | PMID:10973259 more ... |
Giant Platelet Syndrome with Thrombocytopenia | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Giant platelet syndrome with thrombocytopenia | ClinVar | |
Giant Platelet Syndrome with Thrombocytopenia | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Giant platelet syndrome with thrombocytopenia | ClinVar | PMID:10739770 more ... |
Giant Platelet Syndrome with Thrombocytopenia | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Giant platelet syndrome with thrombocytopenia | ClinVar | PMID:11159552 more ... |
Giant Platelet Syndrome with Thrombocytopenia | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Giant platelet syndrome with thrombocytopenia | ClinVar | PMID:11023810 more ... |
Giant Platelet Syndrome with Thrombocytopenia | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Giant platelet syndrome with thrombocytopenia | ClinVar | PMID:11752022 more ... |
Giant Platelet Syndrome with Thrombocytopenia | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Giant platelet syndrome with thrombocytopenia | ClinVar | PMID:15667538 |
Giant Platelet Syndrome with Thrombocytopenia | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Giant platelet syndrome with thrombocytopenia | ClinVar | PMID:25741868 |
Giant Platelet Syndrome with Thrombocytopenia | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Giant platelet syndrome with thrombocytopenia | ClinVar | PMID:24033266, PMID:25741868 |
Giant Platelet Syndrome with Thrombocytopenia | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Giant platelet syndrome with thrombocytopenia | ClinVar | PMID:10603121 more ... |
Hearing Loss | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Hearing impairment | ClinVar | |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: MYH9-related disorder | ClinVar | PMID:19557653 more ... |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Epstein syndrome | ClinVar | PMID:11590545 more ... |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Epstein syndrome | ClinVar | PMID:24033266 more ... |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: MYH9 related disorders | ClinVar | PMID:11159552 more ... |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: May-Hegglin anomaly | ClinVar | PMID:15667538 |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: MYH9 related disorders | ClinVar | PMID:10973259, PMID:11093280 |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: MYH9-related disorder | ClinVar | PMID:24033266, PMID:25741868 |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Fechtner syndrome | ClinVar | PMID:10973260, PMID:12792306 |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: May-Hegglin anomaly | ClinVar | PMID:12792306, PMID:19450438 |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: May-Hegglin anomaly | ClinVar | PMID:10973259, PMID:25741868 |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Epstein syndrome | ClinVar | PMID:11752022 more ... |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Sebastian syndrome | ClinVar | PMID:15613099 |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Sebastian syndrome | ClinVar | PMID:10603121 more ... |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: MYH9-related disorder | ClinVar | PMID:24033266 |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: May-Hegglin anomaly | ClinVar | PMID:10973259 more ... |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: MYH9-related disorder | ClinVar | PMID:11752022 more ... |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: MYH9-related disorder | ClinVar | PMID:11590545 more ... |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Sebastian syndrome | ClinVar | PMID:10739770 more ... |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Sebastian syndrome | ClinVar | PMID:11023810 more ... |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: MYH9-related disorder | ClinVar | |
MYH-9 related disease | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: MYH9-related disorder | ClinVar | PMID:25741868 |
nonsyndromic deafness | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Non-syndromic genetic deafness | ClinVar | PMID:16818291 more ... |
Nonsyndromic Sensorineural Hearing Loss | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Nonsyndromic Hearing Loss, Dominant | ClinVar | PMID:24033266, PMID:25741868 |
Nonsyndromic Sensorineural Hearing Loss | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Nonsyndromic Hearing Loss, Dominant | ClinVar | PMID:11590545 more ... |
Nonsyndromic Sensorineural Hearing Loss | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Nonsyndromic Hearing Loss, Dominant | ClinVar | |
Nonsyndromic Sensorineural Hearing Loss | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Nonsyndromic Hearing Loss, Dominant | ClinVar | PMID:24033266 |
Nonsyndromic Sensorineural Hearing Loss | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Nonsyndromic Hearing Loss, Dominant | ClinVar | PMID:25741868 |
Nonsyndromic Sensorineural Hearing Loss | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Nonsyndromic Hearing Loss, Dominant | ClinVar | PMID:19557653 more ... |
Nonsyndromic Sensorineural Hearing Loss | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Nonsyndromic Hearing Loss, Dominant | ClinVar | PMID:11752022 more ... |
obesity | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Obesity | ClinVar | PMID:25741868 |
thrombocytopenia | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Thrombocytopenia | ClinVar | PMID:25741868 |
Vitelliform Macular Dystrophy 1 | | ISS | RGD:8944101 | 9068941 | ClinVar Annotator: match by term: Macular dystrophy, atypical vitelliform | ClinVar | PMID:24033266 |