SERTAD4 (SERTA domain containing 4) - Rat Genome Database

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Gene: SERTAD4 (SERTA domain containing 4) Canis lupus familiaris
Analyze
Symbol: SERTAD4
Name: SERTA domain containing 4
RGD ID: 12141081
Description: ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); parathyroid carcinoma (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SERTA domain-containing protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.178,856,298 - 8,862,280 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl78,856,330 - 8,860,526 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha78,434,005 - 8,445,065 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.078,552,165 - 8,563,192 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl78,551,640 - 8,562,943 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.178,481,124 - 8,492,152 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.078,577,879 - 8,588,924 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.078,714,991 - 8,726,067 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SERTAD4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.178,856,298 - 8,862,280 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl78,856,330 - 8,860,526 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha78,434,005 - 8,445,065 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.078,552,165 - 8,563,192 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl78,551,640 - 8,562,943 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.178,481,124 - 8,492,152 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.078,577,879 - 8,588,924 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.078,714,991 - 8,726,067 (+)NCBIUU_Cfam_GSD_1.0
SERTAD4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381210,232,796 - 210,246,631 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1210,232,796 - 210,246,631 (+)EnsemblGRCh38hg38GRCh38
GRCh371210,406,141 - 210,419,976 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361208,472,818 - 208,483,083 (+)NCBINCBI36Build 36hg18NCBI36
Build 341206,794,589 - 206,804,833NCBI
Celera1183,629,578 - 183,639,844 (+)NCBICelera
Cytogenetic Map1q32.2NCBI
HuRef1181,079,983 - 181,090,160 (+)NCBIHuRef
CHM1_11211,678,522 - 211,688,788 (+)NCBICHM1_1
T2T-CHM13v2.01209,471,480 - 209,485,315 (+)NCBIT2T-CHM13v2.0
Sertad4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391192,526,796 - 192,538,060 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1192,526,796 - 192,538,064 (-)EnsemblGRCm39 Ensembl
GRCm381192,844,469 - 192,855,752 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1192,844,488 - 192,855,756 (-)EnsemblGRCm38mm10GRCm38
MGSCv371194,670,682 - 194,681,946 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361194,545,212 - 194,556,445 (-)NCBIMGSCv36mm8
Celera1199,726,389 - 199,737,652 (-)NCBICelera
Cytogenetic Map1H6NCBI
cM Map197.55NCBI
Sertad4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813106,889,019 - 106,899,777 (-)NCBIGRCr8
mRatBN7.213104,360,307 - 104,371,064 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13104,360,307 - 104,370,546 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13106,877,959 - 106,888,198 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013108,261,816 - 108,272,055 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013105,479,767 - 105,490,006 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013111,574,545 - 111,585,113 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13111,574,609 - 111,581,019 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013116,126,511 - 116,136,873 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413108,739,942 - 108,750,295 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera13103,790,786 - 103,801,020 (-)NCBICelera
Cytogenetic Map13q27NCBI
Sertad4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554891,947,045 - 1,953,970 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554891,947,819 - 1,958,434 (-)NCBIChiLan1.0ChiLan1.0
SERTAD4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2139,168,286 - 39,181,958 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1139,134,527 - 39,148,088 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01185,789,513 - 185,803,679 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11190,663,690 - 190,672,669 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1190,663,690 - 190,672,666 (+)Ensemblpanpan1.1panPan2
Sertad4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934465,648,427 - 65,655,846 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365572,888,473 - 2,895,492 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365572,888,574 - 2,895,867 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SERTAD4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9132,737,299 - 132,748,448 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19132,737,291 - 132,748,443 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29145,772,676 - 145,783,649 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SERTAD4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12519,224,996 - 19,238,427 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2519,224,806 - 19,233,425 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605519,787,524 - 19,800,998 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sertad4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248071,751,506 - 1,760,634 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SERTAD4
51 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4
Low 5 16 4 2 12 8 10 4
Below cutoff 5 6 6 2 6 6 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000048585   ⟹   ENSCAFP00000036610
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl78,856,330 - 8,860,526 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845005432   ⟹   ENSCAFP00845004319
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl78,551,640 - 8,562,943 (+)Ensembl
RefSeq Acc Id: XM_038480736   ⟹   XP_038336664
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.178,481,124 - 8,492,152 (+)NCBI
RefSeq Acc Id: XM_038542055   ⟹   XP_038397983
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.078,714,991 - 8,726,067 (+)NCBI
RefSeq Acc Id: XM_038562430   ⟹   XP_038418358
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha78,434,005 - 8,445,065 (+)NCBI
RefSeq Acc Id: XM_038606214   ⟹   XP_038462142
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.078,577,879 - 8,588,924 (+)NCBI
RefSeq Acc Id: XM_038670910   ⟹   XP_038526838
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.078,552,165 - 8,563,192 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000036610   ⟸   ENSCAFT00000048585
RefSeq Acc Id: XP_038336664   ⟸   XM_038480736
RefSeq Acc Id: XP_038462142   ⟸   XM_038606214
RefSeq Acc Id: XP_038526838   ⟸   XM_038670910
- UniProtKB: A0A8P0NP16 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038418358   ⟸   XM_038562430
- UniProtKB: A0A8P0NP16 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038397983   ⟸   XM_038542055
- UniProtKB: A0A8P0NP16 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845004319   ⟸   ENSCAFT00845005432
Protein Domains
SERTA

Promoters
RGD ID:13683897
Promoter ID:EPDNEW_C1965
Type:initiation region
Name:SERTAD4_1
Description:SERTA domain containing 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.178,856,312 - 8,856,372EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000031193 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00845003084 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000048585.3 UniProtKB/TrEMBL
  ENSCAFT00845005432.1 UniProtKB/TrEMBL
InterPro SERTA_dom UniProtKB/TrEMBL
  SERTAD4 UniProtKB/TrEMBL
NCBI Gene SERTAD4 ENTREZGENE
PANTHER PTHR14272 UniProtKB/TrEMBL
  SERTA DOMAIN-CONTAINING PROTEIN 4 UniProtKB/TrEMBL
Pfam SERTA UniProtKB/TrEMBL
PROSITE SERTA UniProtKB/TrEMBL
UniProt A0A8I3RR50_CANLF UniProtKB/TrEMBL
  A0A8P0NP16 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:46045 ENTREZGENE