AUNIP (aurora kinase A and ninein interacting protein) - Rat Genome Database

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Gene: AUNIP (aurora kinase A and ninein interacting protein) Canis lupus familiaris
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Symbol: AUNIP
Name: aurora kinase A and ninein interacting protein
RGD ID: 12139285
Description: ENCODES a protein that exhibits damaged DNA binding (inferred); INVOLVED IN double-strand break repair via homologous recombination (inferred); negative regulation of double-strand break repair via nonhomologous end joining (inferred); spindle organization (inferred); ASSOCIATED WITH autosomal recessive hypercholesterolemia (ortholog); genetic disease (ortholog); retinitis pigmentosa 59 (ortholog); FOUND IN centrosome (inferred); site of DNA damage (inferred); spindle pole (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: aurora kinase A and ninein-interacting protein; C2H1orf135
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,097,435 - 74,116,824 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl274,097,508 - 74,118,085 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha270,672,437 - 70,691,825 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,659,379 - 74,678,769 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1271,482,989 - 71,502,360 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0272,489,873 - 72,509,251 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0273,493,750 - 73,513,141 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
AUNIP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,097,435 - 74,116,824 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl274,097,508 - 74,118,085 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha270,672,437 - 70,691,825 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,659,379 - 74,678,769 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1271,482,989 - 71,502,360 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0272,489,873 - 72,509,251 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0273,493,750 - 73,513,141 (+)NCBIUU_Cfam_GSD_1.0
AUNIP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38125,831,906 - 25,859,457 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl125,831,913 - 25,859,458 (-)EnsemblGRCh38hg38GRCh38
GRCh37126,158,397 - 26,185,948 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,033,084 - 26,058,435 (-)NCBINCBI36Build 36hg18NCBI36
Celera124,556,593 - 24,581,939 (-)NCBICelera
Cytogenetic Map1p36.11NCBI
HuRef124,416,431 - 24,441,778 (-)NCBIHuRef
CHM1_1126,273,766 - 26,299,115 (-)NCBICHM1_1
T2T-CHM13v2.0125,669,339 - 25,696,890 (-)NCBIT2T-CHM13v2.0
Aunip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394134,238,310 - 134,251,233 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4134,238,310 - 134,251,238 (+)EnsemblGRCm39 Ensembl
GRCm384134,510,999 - 134,523,922 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4134,510,999 - 134,523,927 (+)EnsemblGRCm38mm10GRCm38
MGSCv374134,066,914 - 134,079,837 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364133,783,075 - 133,795,998 (+)NCBIMGSCv36mm8
Celera4132,704,383 - 132,706,845 (+)NCBICelera
Cytogenetic Map4D2.3- D3NCBI
cM Map466.82NCBI
Aunip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85152,006,021 - 152,018,614 (+)NCBIGRCr8
mRatBN7.25146,722,329 - 146,734,924 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5146,722,337 - 146,736,501 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5149,424,297 - 149,436,863 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05151,194,467 - 151,207,061 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05151,180,540 - 151,193,107 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05152,721,799 - 152,734,577 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5152,721,940 - 152,734,572 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05156,507,397 - 156,520,175 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45153,267,331 - 153,280,190 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5145,137,245 - 145,149,834 (+)NCBICelera
Cytogenetic Map5q36NCBI
Aunip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554525,325,426 - 5,336,833 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554525,323,345 - 5,336,589 (-)NCBIChiLan1.0ChiLan1.0
AUNIP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21201,014,645 - 201,042,028 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11200,112,601 - 200,139,944 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0125,090,690 - 25,118,062 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1126,158,124 - 26,185,578 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,157,953 - 26,185,578 (-)Ensemblpanpan1.1panPan2
Aunip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505844,584,681 - 44,605,399 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647410,409,022 - 10,430,187 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647410,409,463 - 10,430,158 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AUNIP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl683,272,788 - 83,316,418 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1683,276,977 - 83,316,642 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2676,834,010 - 76,872,388 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AUNIP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120106,912,338 - 106,936,183 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20106,912,431 - 106,939,583 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660339,480,686 - 9,504,516 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aunip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247649,920,935 - 9,948,850 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247649,920,772 - 9,950,133 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in AUNIP
107 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 8
Low 2 4 4 4 6
Below cutoff 3 5 18 2 6 2 6 12 10 6

Sequence


RefSeq Acc Id: ENSCAFT00000020219   ⟹   ENSCAFP00000018756
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl274,097,508 - 74,118,085 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000083033   ⟹   ENSCAFP00000045068
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl274,097,508 - 74,116,170 (+)Ensembl
RefSeq Acc Id: XM_003433735   ⟹   XP_003433783
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1274,097,435 - 74,116,824 (+)NCBI
Dog10K_Boxer_Tasha270,672,437 - 70,691,825 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038462867   ⟹   XP_038318795
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha270,687,359 - 70,691,825 (+)NCBI
RefSeq Acc Id: XM_038470672   ⟹   XP_038326600
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1271,482,989 - 71,502,360 (+)NCBI
RefSeq Acc Id: XM_038470673   ⟹   XP_038326601
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1271,497,897 - 71,502,360 (+)NCBI
RefSeq Acc Id: XM_038531533   ⟹   XP_038387461
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0273,493,750 - 73,513,141 (+)NCBI
RefSeq Acc Id: XM_038531534   ⟹   XP_038387462
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0273,508,679 - 73,513,141 (+)NCBI
RefSeq Acc Id: XM_038595762   ⟹   XP_038451690
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0272,489,873 - 72,509,251 (+)NCBI
RefSeq Acc Id: XM_038595763   ⟹   XP_038451691
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0272,504,786 - 72,509,251 (+)NCBI
RefSeq Acc Id: XM_038659837   ⟹   XP_038515765
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0274,659,379 - 74,678,769 (+)NCBI
RefSeq Acc Id: XM_038659838   ⟹   XP_038515766
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0274,674,298 - 74,678,769 (+)NCBI
RefSeq Acc Id: XP_003433783   ⟸   XM_003433735
- Peptide Label: isoform X1
- UniProtKB: A0A8P0NVD5 (UniProtKB/TrEMBL),   A0A8C0NW66 (UniProtKB/TrEMBL),   A0A8I3S073 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000045068   ⟸   ENSCAFT00000083033
RefSeq Acc Id: ENSCAFP00000018756   ⟸   ENSCAFT00000020219
RefSeq Acc Id: XP_038326600   ⟸   XM_038470672
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038326601   ⟸   XM_038470673
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038451690   ⟸   XM_038595762
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038451691   ⟸   XM_038595763
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038515765   ⟸   XM_038659837
- Peptide Label: isoform X1
- UniProtKB: A0A8P0NVD5 (UniProtKB/TrEMBL),   A0A8C0NW66 (UniProtKB/TrEMBL),   A0A8I3S073 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038515766   ⟸   XM_038659838
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LAN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038318795   ⟸   XM_038462867
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LAN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038387461   ⟸   XM_038531533
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NW66 (UniProtKB/TrEMBL),   A0A8I3S073 (UniProtKB/TrEMBL),   A0A8P0NVD5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038387462   ⟸   XM_038531534
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LAN3 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000012751 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030016306 UniProtKB/TrEMBL
  ENSCAFG00040006067 UniProtKB/TrEMBL
  ENSCAFG00845013577 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000020219.4 UniProtKB/TrEMBL
  ENSCAFT00000083033.2 UniProtKB/TrEMBL
  ENSCAFT00030030131.1 UniProtKB/TrEMBL
  ENSCAFT00040011356.1 UniProtKB/TrEMBL
  ENSCAFT00845024201.1 UniProtKB/TrEMBL
InterPro AUNIP UniProtKB/TrEMBL
KEGG Report cfa:100688925 UniProtKB/TrEMBL
NCBI Gene AUNIP ENTREZGENE
PANTHER AURORA KINASE A AND NINEIN-INTERACTING PROTEIN UniProtKB/TrEMBL
  PTHR14526 UniProtKB/TrEMBL
Pfam AIB UniProtKB/TrEMBL
UniProt A0A8C0LAN3 ENTREZGENE
  A0A8C0NW66 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S073 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NVD5 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:38309 ENTREZGENE