CA5A (carbonic anhydrase 5A) - Rat Genome Database

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Gene: CA5A (carbonic anhydrase 5A) Canis lupus familiaris
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Symbol: CA5A
Name: carbonic anhydrase 5A
RGD ID: 12137251
Description: ENCODES a protein that exhibits carbonate dehydratase activity (ortholog); ASSOCIATED WITH 16Q24.3 Microdeletion Syndrome (ortholog); CARBONIC ANHYDRASE VA DEFICIENCY, HYPERAMMONEMIA DUE TO (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: carbonic anhydrase 5A, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1565,269,855 - 65,297,593 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl565,269,635 - 65,296,777 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha565,280,118 - 65,307,768 (+)NCBI
ROS_Cfam_1.0565,489,652 - 65,517,389 (+)NCBI
UMICH_Zoey_3.1565,515,185 - 65,542,854 (+)NCBI
UNSW_CanFamBas_1.0565,346,901 - 65,374,559 (+)NCBI
UU_Cfam_GSD_1.0565,753,935 - 65,781,642 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
mitochondrion  (IBA,ISO)

Molecular Function

References

Genomics

Comparative Map Data
CA5A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1565,269,855 - 65,297,593 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl565,269,635 - 65,296,777 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha565,280,118 - 65,307,768 (+)NCBI
ROS_Cfam_1.0565,489,652 - 65,517,389 (+)NCBI
UMICH_Zoey_3.1565,515,185 - 65,542,854 (+)NCBI
UNSW_CanFamBas_1.0565,346,901 - 65,374,559 (+)NCBI
UU_Cfam_GSD_1.0565,753,935 - 65,781,642 (+)NCBI
CA5A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1687,881,546 - 87,936,580 (-)EnsemblGRCh38hg38GRCh38
GRCh381687,881,549 - 87,936,575 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371687,915,155 - 87,970,135 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361686,479,126 - 86,527,613 (-)NCBINCBI36hg18NCBI36
Build 341686,479,125 - 86,527,613NCBI
Celera1672,219,173 - 72,267,375 (-)NCBI
Cytogenetic Map16q24.2NCBI
HuRef1673,662,132 - 73,710,650 (-)NCBIHuRef
CHM1_11689,333,043 - 89,381,480 (-)NCBICHM1_1
Car5a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398122,642,874 - 122,671,651 (-)NCBIGRCm39mm39
GRCm39 Ensembl8122,642,865 - 122,671,643 (-)Ensembl
GRCm388121,916,135 - 121,944,912 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8121,916,126 - 121,944,904 (-)EnsemblGRCm38mm10GRCm38
MGSCv378124,440,035 - 124,468,812 (-)NCBIGRCm37mm9NCBIm37
MGSCv368121,987,915 - 122,017,051 (-)NCBImm8
MGSCv368124,802,236 - 124,830,994 (-)NCBImm8
Celera8126,138,230 - 126,172,629 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map870.81NCBI
Ca5a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21949,973,092 - 50,002,948 (-)NCBI
Rnor_6.0 Ensembl1954,731,859 - 54,761,670 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01954,731,829 - 54,761,697 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01965,451,126 - 65,480,815 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41952,158,607 - 52,188,664 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11952,163,493 - 52,193,545 (-)NCBI
Celera1949,218,046 - 49,247,995 (-)NCBICelera
Cytogenetic Map19q12NCBI
Ca5a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555412,139,920 - 2,160,597 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555412,141,450 - 2,159,955 (-)NCBIChiLan1.0ChiLan1.0
CA5A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11687,887,288 - 87,903,159 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01668,564,400 - 68,618,614 (-)NCBIMhudiblu_PPA_v0panPan3
Ca5a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934925,719,672 - 25,742,042 (+)NCBI
SpeTri2.0NW_0049366411,478,285 - 1,495,490 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA5A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl61,505,566 - 1,538,494 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.161,495,615 - 1,539,390 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CA5A
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1573,284,536 - 73,333,629 (-)NCBI
Ca5a
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247461,293,619 - 1,323,067 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6 6 6
Low 6
Below cutoff 4 5 14 6 5 4 6 8 8 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000031659   ⟹   ENSCAFP00000029473
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl565,269,635 - 65,296,777 (+)Ensembl
RefSeq Acc Id: XM_005620581   ⟹   XP_005620638
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1565,269,855 - 65,297,593 (+)NCBI
Dog10K_Boxer_Tasha565,280,118 - 65,307,768 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038476916   ⟹   XP_038332844
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1565,515,185 - 65,542,854 (+)NCBI
RefSeq Acc Id: XM_038538088   ⟹   XP_038394016
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0565,753,935 - 65,781,642 (+)NCBI
RefSeq Acc Id: XM_038602210   ⟹   XP_038458138
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0565,346,901 - 65,374,559 (+)NCBI
RefSeq Acc Id: XM_038666827   ⟹   XP_038522755
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0565,489,652 - 65,517,389 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_005620638   ⟸   XM_005620581
- Sequence:
RefSeq Acc Id: ENSCAFP00000029473   ⟸   ENSCAFT00000031659
RefSeq Acc Id: XP_038332844   ⟸   XM_038476916
RefSeq Acc Id: XP_038458138   ⟸   XM_038602210
RefSeq Acc Id: XP_038522755   ⟸   XM_038666827
RefSeq Acc Id: XP_038394016   ⟸   XM_038538088
Protein Domains
Alpha-carbonic anhydrase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000019899 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000029473 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000031659 UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/TrEMBL
InterPro CA_dom UniProtKB/TrEMBL
  CA_dom_sf UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class_CS UniProtKB/TrEMBL
NCBI Gene CA5A ENTREZGENE
PANTHER PTHR18952 UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
PROSITE ALPHA_CA_1 UniProtKB/TrEMBL
  ALPHA_CA_2 UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/TrEMBL
UniProt F1PHA0_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:53312 ENTREZGENE