FABP4 (fatty acid binding protein 4) - Rat Genome Database

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Gene: FABP4 (fatty acid binding protein 4) Canis lupus familiaris
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Symbol: FABP4
Name: fatty acid binding protein 4
RGD ID: 12137219
Description: ENCODES a protein that exhibits hormone receptor binding (ortholog); long-chain fatty acid binding (ortholog); long-chain fatty acid transmembrane transporter activity (ortholog); INVOLVED IN brown fat cell differentiation (ortholog); cellular response to lithium ion (ortholog); cellular response to tumor necrosis factor (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); contact dermatitis (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fatty acid-binding protein, adipocyte
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12928,651,550 - 28,656,255 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2928,652,146 - 28,656,228 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2928,930,953 - 28,935,672 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02928,782,981 - 28,787,700 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2928,782,960 - 28,787,677 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12928,853,143 - 28,857,859 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02928,866,783 - 28,871,503 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02929,223,638 - 29,228,357 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
FABP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12928,651,550 - 28,656,255 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2928,652,146 - 28,656,228 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2928,930,953 - 28,935,672 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02928,782,981 - 28,787,700 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2928,782,960 - 28,787,677 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12928,853,143 - 28,857,859 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02928,866,783 - 28,871,503 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02929,223,638 - 29,228,357 (-)NCBIUU_Cfam_GSD_1.0
FABP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38881,478,419 - 81,483,233 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl881,478,419 - 81,483,236 (-)EnsemblGRCh38hg38GRCh38
GRCh37882,390,654 - 82,395,468 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36882,553,481 - 82,558,004 (-)NCBINCBI36Build 36hg18NCBI36
Build 34882,553,480 - 82,558,004NCBI
Celera878,395,692 - 78,400,433 (-)NCBICelera
Cytogenetic Map8q21.13NCBI
HuRef877,880,663 - 77,885,404 (-)NCBIHuRef
CHM1_1882,442,333 - 82,447,074 (-)NCBICHM1_1
T2T-CHM13v2.0881,910,018 - 81,914,832 (-)NCBIT2T-CHM13v2.0
Fabp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39310,269,406 - 10,273,653 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl310,269,148 - 10,273,636 (-)EnsemblGRCm39 Ensembl
GRCm38310,204,342 - 10,208,616 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl310,204,088 - 10,208,576 (-)EnsemblGRCm38mm10GRCm38
MGSCv37310,204,342 - 10,208,576 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36310,186,879 - 10,191,086 (-)NCBIMGSCv36mm8
Celera310,234,558 - 10,238,773 (-)NCBICelera
Cytogenetic Map3A1NCBI
cM Map32.56NCBI
Fabp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8293,488,251 - 93,492,961 (+)NCBIGRCr8
mRatBN7.2291,580,879 - 91,585,567 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl291,580,885 - 91,585,578 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx298,071,495 - 98,075,852 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0296,192,481 - 96,196,839 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0291,249,333 - 91,253,689 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0293,792,666 - 93,797,267 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl293,792,601 - 93,797,305 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02113,547,703 - 113,552,304 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4293,536,133 - 93,540,734 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1293,481,094 - 93,485,696 (+)NCBI
Celera287,183,534 - 87,187,814 (+)NCBICelera
Cytogenetic Map2q23NCBI
Fabp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955444141,840 - 148,467 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955444141,955 - 146,279 (+)NCBIChiLan1.0ChiLan1.0
FABP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2797,216,084 - 97,221,109 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1872,843,910 - 72,848,935 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0878,001,476 - 78,006,006 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1879,624,899 - 79,629,442 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl879,624,899 - 79,630,168 (-)Ensemblpanpan1.1panPan2
Fabp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530350,532,455 - 50,536,868 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366562,722,713 - 2,729,046 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366562,722,970 - 2,727,383 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FABP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl455,096,404 - 55,101,896 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1455,096,400 - 55,101,209 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FABP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1876,895,516 - 76,900,153 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl876,894,512 - 76,900,212 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603964,295,119 - 64,299,651 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in FABP4
49 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High 1 6
Medium 3 5 8 1 5 6 1 5
Low 2 8 1 2 1 6 8 4
Below cutoff 6 5 3 5 5 1

Sequence


RefSeq Acc Id: ENSCAFT00000013432   ⟹   ENSCAFP00000012427
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2928,652,146 - 28,656,228 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000059992   ⟹   ENSCAFP00000063003
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2928,652,146 - 28,653,849 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845026752   ⟹   ENSCAFP00845021076
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2928,782,960 - 28,787,677 (-)Ensembl
RefSeq Acc Id: XM_038441472   ⟹   XP_038297400
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02928,782,981 - 28,787,700 (-)NCBI
RefSeq Acc Id: XM_038516042   ⟹   XP_038371970
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12928,853,143 - 28,857,859 (-)NCBI
RefSeq Acc Id: XM_038579607   ⟹   XP_038435535
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02929,223,638 - 29,228,357 (-)NCBI
RefSeq Acc Id: XM_038643854   ⟹   XP_038499782
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02928,866,783 - 28,871,503 (-)NCBI
RefSeq Acc Id: XM_845069   ⟹   XP_850162
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12928,651,550 - 28,656,255 (-)NCBI
Dog10K_Boxer_Tasha2928,930,953 - 28,935,672 (-)NCBI
Sequence:
RefSeq Acc Id: XP_850162   ⟸   XM_845069
- UniProtKB: A0A8C0T7B6 (UniProtKB/TrEMBL),   A0A8I3NQN1 (UniProtKB/TrEMBL),   A0A8C0P568 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000063003   ⟸   ENSCAFT00000059992
RefSeq Acc Id: ENSCAFP00000012427   ⟸   ENSCAFT00000013432
RefSeq Acc Id: XP_038371970   ⟸   XM_038516042
RefSeq Acc Id: XP_038499782   ⟸   XM_038643854
RefSeq Acc Id: XP_038297400   ⟸   XM_038441472
- UniProtKB: A0A8C0T7B6 (UniProtKB/TrEMBL),   A0A8I3NQN1 (UniProtKB/TrEMBL),   A0A8C0P568 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038435535   ⟸   XM_038579607
- UniProtKB: A0A8C0P568 (UniProtKB/TrEMBL),   A0A8C0T7B6 (UniProtKB/TrEMBL),   A0A8I3NQN1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845021076   ⟸   ENSCAFT00845026752

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000025410 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030019843 UniProtKB/TrEMBL
  ENSCAFG00040019793 UniProtKB/TrEMBL
  ENSCAFG00845014963 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000013432.5 UniProtKB/TrEMBL
  ENSCAFT00030036441.1 UniProtKB/TrEMBL
  ENSCAFT00040036578.1 UniProtKB/TrEMBL
  ENSCAFT00845026752 ENTREZGENE
  ENSCAFT00845026752.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.128.20 UniProtKB/TrEMBL
InterPro Calycin UniProtKB/TrEMBL
  Fatty_acid-bd UniProtKB/TrEMBL
  ILBP UniProtKB/TrEMBL
  Lipocln_cytosolic_FA-bd_dom UniProtKB/TrEMBL
KEGG Report cfa:608476 UniProtKB/TrEMBL
NCBI Gene FABP4 ENTREZGENE
PANTHER PTHR11955 UniProtKB/TrEMBL
  PTHR11955:SF83 UniProtKB/TrEMBL
Pfam Lipocalin UniProtKB/TrEMBL
PRINTS FATTYACIDBP UniProtKB/TrEMBL
PROSITE FABP UniProtKB/TrEMBL
Superfamily-SCOP SSF50814 UniProtKB/TrEMBL
UniProt A0A8C0P568 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0T7B6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NQN1 ENTREZGENE, UniProtKB/TrEMBL