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Gene: RUBCNL (rubicon like autophagy enhancer) Canis lupus familiaris

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Symbol:

RUBCNL

Name:

rubicon like autophagy enhancer

RGD ID:

12137006

Description:

ENCODES a protein that exhibits phosphatidylinositol-3-phosphate binding (inferred); phosphatidylinositol-4-phosphate binding (inferred); phosphatidylinositol-5-phosphate binding (inferred); INVOLVED IN regulation of glycogen metabolic process (ortholog); regulation of lipid metabolic process (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN autophagosome membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

KIAA0226-like ortholog; KIAA0226L; rubicon like autophagy regulator; RUN and cysteine rich domain containing beclin 1 interacting protein like; uncharacterized protein KIAA0226-like homolog

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	22	4,874,384 - 4,903,044 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	22	4,874,575 - 4,903,033 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	22	4,916,030 - 4,953,319 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	22	4,980,314 - 5,017,734 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	22	4,976,624 - 5,016,959 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	22	4,762,415 - 4,800,374 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	22	4,825,919 - 4,863,052 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	22	4,830,727 - 4,868,748 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

prostate cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

autophagosome maturation (IBA,IEA)

autophagosome-endosome fusion (IBA,IEA)

autophagosome-lysosome fusion (IBA,IEA)

autophagy (IEA)

regulation of glycogen metabolic process (ISO)

regulation of lipid metabolic process (ISO)

Cellular Component

autophagosome membrane (IBA,IEA)

intracellular membrane-bounded organelle (IBA)

Molecular Function

phosphatidylinositol phosphate binding (IBA)

phosphatidylinositol-3-phosphate binding (IEA)

phosphatidylinositol-4-phosphate binding (IEA)

phosphatidylinositol-5-phosphate binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

RUBCNL
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	22	4,874,384 - 4,903,044 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	22	4,874,575 - 4,903,033 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	22	4,916,030 - 4,953,319 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	22	4,980,314 - 5,017,734 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	22	4,976,624 - 5,016,959 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	22	4,762,415 - 4,800,374 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	22	4,825,919 - 4,863,052 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	22	4,830,727 - 4,868,748 (+)	NCBI		UU_Cfam_GSD_1.0

RUBCNL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	13	46,334,681 - 46,390,042 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	13	46,334,681 - 46,438,190 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	13	46,908,816 - 46,964,177 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	13	45,814,137 - 45,859,636 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	13	45,815,100 - 45,859,385	NCBI
Celera	13	27,971,122 - 28,016,591 (-)	NCBI		Celera
Cytogenetic Map	13	q14.13	NCBI
HuRef	13	27,713,683 - 27,759,154 (-)	NCBI		HuRef
CHM1_1	13	46,884,932 - 46,930,398 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	13	45,555,685 - 45,611,047 (-)	NCBI		T2T-CHM13v2.0

Rubcnl
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	75,253,467 - 75,289,977 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	75,253,467 - 75,289,972 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	75,015,987 - 75,052,537 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	75,016,027 - 75,052,532 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	75,415,834 - 75,452,339 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	73,736,988 - 73,786,572 (+)	NCBI		MGSCv36	mm8
Celera	14	72,515,864 - 72,552,426 (+)	NCBI		Celera
Cytogenetic Map	14	D3	NCBI
cM Map	14	39.53	NCBI

Rubcnl
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	56,741,897 - 56,807,086 (+)	NCBI		GRCr8
mRatBN7.2	15	50,332,458 - 50,377,494 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	50,332,418 - 50,400,849 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	15	57,065,512 - 57,109,197 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	57,065,428 - 57,102,599 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	60,777,541 - 60,821,362 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	55,894,968 - 55,913,448 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	55,815,486 - 55,929,226 (+)	NCBI
Celera	15	49,964,999 - 50,008,655 (+)	NCBI		Celera
Cytogenetic Map	15	q11	NCBI

Rubcnl
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955431	140,922 - 206,951 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955431	140,999 - 206,570 (-)	NCBI	ChiLan1.0	ChiLan1.0

RUBCNL
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	14	44,953,710 - 45,049,079 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	13	36,007,854 - 36,111,800 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	13	26,594,545 - 26,600,412 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

Rubcnl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	156,428,120 - 156,521,426 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936857	839,418 - 870,961 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RUBCNL
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	11	20,995,688 - 21,036,014 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	11	20,995,439 - 21,036,429 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	11	21,427,767 - 21,445,259 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RUBCNL
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	3	24,400,507 - 24,445,514 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	3	24,399,500 - 24,430,601 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666057	19,554,526 - 19,600,019 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rubcnl
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624748	8,605,272 - 8,652,785 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in RUBCNL
411 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005634082	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_014106402	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038430951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038430952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038430953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038430954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038456786	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038456787	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038506333	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038506334	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038506335	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038506336	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038569533	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038569534	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038569535	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038569536	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038633699	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038633700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038633701	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038633702	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000251	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000060	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000360	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000007212 ⟹ ENSCAFP00000006678

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	22	4,874,575 - 4,903,033 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845013829 ⟹ ENSCAFP00845010729

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	22	4,976,624 - 5,016,959 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845013888 ⟹ ENSCAFP00845010769

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	22	4,993,505 - 5,016,959 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845014012 ⟹ ENSCAFP00845010860

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	22	4,997,855 - 5,016,959 (+)	Ensembl

RefSeq Acc Id:

XM_005634082 ⟹ XP_005634139

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	22	4,879,360 - 4,903,044 (+)	NCBI
Dog10K_Boxer_Tasha	22	4,929,600 - 4,953,319 (+)	NCBI

Sequence:

show sequence

CCGGACCCAGGGCGGTGCTGCTCCACCGCCTCCAGCGCAGGAAGGTGCTGTGCAAGGAAGAACC
TTGAATCCCTTCTCACCAGAGGCATTCCTGCTCCCTGTCGATGTTGAAAAGGAAAACGCCCACT
TCTACGTTGCGGATATGATTATAGCGGCAATGGAGAAGATCAAGTACGCCATCCTGAGTCAGCA
GCACCCAGACCCCTGGGGTGAGGAAGAGGCCAGGGGGGCACCCGGCAGTGGTCACGCTGATGCT
GAGACGACCTTCTATAGCAACATGAAGCAAGGATCTGGGTCTTCCAACTCTTCTGACAGCGGCT
ATGAAGGTTGTGCTATGTTACAGGGCAGCCCGGTGGCTGGGACACCCACTTACGGTGACGTTCT
CAAAGAAGCCTGTAAATGTGACTTTGATGACTTTGTTGTCGTAGAACTTGGTGAGTTTAGCAAT
ATCACAGAAACCTGTGGATGCTCCTGCAGCTCTTCCAAGAGTATCGTTTATGAGCCAGACTTCA
ATTCCGCTGAGCTAATAGCCAAAGAGTTGTACCGAGTATTCCAGAAGTGCTGGATGTGGTCAGA
AGTTCATCATCAGCTGGAAGGTTCTCCCAATGCCGCTGGCTCCATAGTTGTAAATGAAGAACGT
GTCCGGAAAGACTTTGAATCCAGTGTGGATGTGGTTCAGGAAATTAAACTTCAGTCGAAGATCA
GAGAGGCTGAAGACTGGGAGCCCCCCCGATTTCAAATCATATTTGATGTTCATCCACCACTCAA
GAGGGATCTCGTGGTAGCAGCCCAGAACTTTCTGTGTGCTGGCTGTGGCACGCCGATAGAACCC
AAGTTCGTGAGGCGCCTGCGGTACTGCGACTACCTGGGCAAGTATTTCTGTGACTGCTGCCACA
CCTACGCAGACTCCTGCATCCCGGCCCGGATCCTGAGCACGTGGGACTTCAGGAGGTACTACGT
CAGCAACTTCTCCAAGCGCCTGCTGGACAGCGTGTGGCACCAGCCCATTTTCAATTTGCTGAGC
GCAGGCCACAGCCTGTACGCCAAGGCCAAGGAGCTGGACCGAGCCAGGGAAATCCAGGAGCAAC
TTTTTCAGATCAAGAAGCTGTTGAAGACCTGCAGGTTTGCTGAAAGCGCAGTAAAGGCATTTGA
GCAGGTGCCGAGGCACTTGACCGACGATCTCCACCTGTTCTCTCTGGAGGACCTGGTCAGGGTC
AAGAAGAGGCTGCTGGTGCCCTTGCTCAAGGACATTCTCAAAGCTTCCCTTGCACATGTGGCCA
GCTGTGAGCTGTGTCAAGGAAAGGGCTTCATCTGCGAATTTTGCCAGAGTACAGCCGTCATCTT
CCCATTTCAGACCGAAACGTGTAGACGATGTGCAGGGTGCAGAGCTTGCTTTCACAAGCAGTGC
TTCCAGTCCTCCGAGTGCCCCCGGTGTGCCAGGATCACAGCCAGGAGAAGACTTCTGGAAAGTT
TACCCTCTGCAGCAACATGAGCCCCTGACCACGGTGGAAAAGACTGTTCAACATGCCTTATAAC
ACCGATTTGTGTCGATTATTGACAATCGTGTTTCAGATTTTGAGTATTGTATATTAAGAAAAAA
TGGTGGCCAATCTTTTTTATTATATATATATATATATATTTAATGTGTTACAAAGAATGCACAT
TTTTTTGTTATTAAGCATAGGTTTGTTACTGGTGGTCTTGTTTACAAACGTTCAGTGTTTTTGC
TGCTACTGTTTTTTTCTTAAGAATTTTTTTTTGATACTTCTTAAAATTGCCTTTGAATGGTTGC
ATTCAGCTGATACTGGAGCTATTTTTTTATGAATTGTTAACTGACAAGGCAAATTACTCAGTTT
GTCTTTCTACAAAGCTAGTTTTAAACGAATTGGTACTTTCAATGAACAAAAATGCGAACAATGA
TCTGTTTACTCCGGGGTTCTTTTCCCCCCCGACTTAAATGCCACTTTGTAATTGCATCCGTGTT
TTAGATCATACTTATTCCGGGGTTGGCACAGGGAGTCCCTGTTCCCTCTGCATCTATGTCCAGA
TGAGTGTGAGCTGCTTAGCGGGGCTGCAGCTGCCGTTCGAAGGTGTCGCCCCTGCGGGCCACTC
TCAGGCACACACCGACCCTGTACTTGTCCTCTCCCTTCCACACACTAAATCAAGGGCTGCATGG
CTGAGTCGAACCTCATCCCTGCCCTTTAGGATTTTGTCTCGTGGATATAAAACTGAACATAAGG
TATTGACAAACTTAAACTGTGGGAAAGTCCCGTCATTGAGCAATGTGATTTTAGTAATGACAAT
AAAATCATGGACCTCAATTAAAAAGGTGAGGTAAATCGCTAAAC

hide sequence

RefSeq Acc Id:

XM_014106402 ⟹ XP_013961877

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	22	4,874,384 - 4,903,044 (+)	NCBI
Dog10K_Boxer_Tasha	22	4,924,724 - 4,953,319 (+)	NCBI

Sequence:

show sequence

ACTGAGTCGTCCACCCCTTTTGCAAAAGTTGCGTCTTTGCCGTTGGCATTGTGGCTCCGAGGTT
GTCCTCGTGATGCAGTCATTCTTGACAGAGCCACACTGACTTTGATGGGCAGAGGCCCAACCAG
AATGACTTGGCAGGGGGAACCCAAGAGTCTCTCTTTTCATCTAGGACCTTTGCTGCTTTATATA
TGTTAACTAATAATCTGGCCTGTGCTCACCCTCAACAGGAAACTCCTGATAGAAATGACGGTGC
TGTGCAAGGAAGAACCTTGAATCCCTTCTCACCAGAGGCATTCCTGCTCCCTGTCGATGTTGAA
AAGGAAAACGCCCACTTCTACGTTGCGGATATGATTATAGCGGCAATGGAGAAGATCAAGTACG
CCATCCTGAGTCAGCAGCACCCAGACCCCTGGGGTGAGGAAGAGGCCAGGGGGGCACCCGGCAG
TGGTCACGCTGATGCTGAGACGACCTTCTATAGCAACATGAAGCAAGGATCTGGGTCTTCCAAC
TCTTCTGACAGCGGCTATGAAGGTTGTGCTATGTTACAGGGCAGCCCGGTGGCTGGGACACCCA
CTTACGGTGACGTTCTCAAAGAAGCCTGTAAATGTGACTTTGATGACTTTGTTGTCGTAGAACT
TGGTGAGTTTAGCAATATCACAGAAACCTGTGGATGCTCCTGCAGCTCTTCCAAGAGTATCGTT
TATGAGCCAGACTTCAATTCCGCTGAGCTAATAGCCAAAGAGTTGTACCGAGTATTCCAGAAGT
GCTGGATGTGGTCAGAAGTTCATCATCAGCTGGAAGGTTCTCCCAATGCCGCTGGCTCCATAGT
TGTAAATGAAGAACGTGTCCGGAAAGACTTTGAATCCAGTGTGGATGTGGTTCAGGAAATTAAA
CTTCAGTCGAAGATCAGAGAGGCTGAAGACTGGGAGCCCCCCCGATTTCAAATCATATTTGATG
TTCATCCACCACTCAAGAGGGATCTCGTGGTAGCAGCCCAGAACTTTCTGTGTGCTGGCTGTGG
CACGCCGATAGAACCCAAGTTCGTGAGGCGCCTGCGGTACTGCGACTACCTGGGCAAGTATTTC
TGTGACTGCTGCCACACCTACGCAGACTCCTGCATCCCGGCCCGGATCCTGAGCACGTGGGACT
TCAGGAGGTACTACGTCAGCAACTTCTCCAAGCGCCTGCTGGACAGCGTGTGGCACCAGCCCAT
TTTCAATTTGCTGAGCGCAGGCCACAGCCTGTACGCCAAGGCCAAGGAGCTGGACCGAGCCAGG
GAAATCCAGGAGCAACTTTTTCAGATCAAGAAGCTGTTGAAGACCTGCAGGTTTGCTGAAAGCG
CAGTAAAGGCATTTGAGCAGGTGCCGAGGCACTTGACCGACGATCTCCACCTGTTCTCTCTGGA
GGACCTGGTCAGGGTCAAGAAGAGGCTGCTGGTGCCCTTGCTCAAGGACATTCTCAAAGCTTCC
CTTGCACATGTGGCCAGCTGTGAGCTGTGTCAAGGAAAGGGCTTCATCTGCGAATTTTGCCAGA
GTACAGCCGTCATCTTCCCATTTCAGACCGAAACGTGTAGACGATGTGCAGGGTGCAGAGCTTG
CTTTCACAAGCAGTGCTTCCAGTCCTCCGAGTGCCCCCGGTGTGCCAGGATCACAGCCAGGAGA
AGACTTCTGGAAAGTTTACCCTCTGCAGCAACATGAGCCCCTGACCACGGTGGAAAAGACTGTT
CAACATGCCTTATAACACCGATTTGTGTCGATTATTGACAATCGTGTTTCAGATTTTGAGTATT
GTATATTAAGAAAAAATGGTGGCCAATCTTTTTTATTATATATATATATATATATTTAATGTGT
TACAAAGAATGCACATTTTTTTGTTATTAAGCATAGGTTTGTTACTGGTGGTCTTGTTTACAAA
CGTTCAGTGTTTTTGCTGCTACTGTTTTTTTCTTAAGAATTTTTTTTTGATACTTCTTAAAATT
GCCTTTGAATGGTTGCATTCAGCTGATACTGGAGCTATTTTTTTATGAATTGTTAACTGACAAG
GCAAATTACTCAGTTTGTCTTTCTACAAAGCTAGTTTTAAACGAATTGGTACTTTCAATGAACA
AAAATGCGAACAATGATCTGTTTACTCCGGGGTTCTTTTCCCCCCCGACTTAAATGCCACTTTG
TAATTGCATCCGTGTTTTAGATCATACTTATTCCGGGGTTGGCACAGGGAGTCCCTGTTCCCTC
TGCATCTATGTCCAGATGAGTGTGAGCTGCTTAGCGGGGCTGCAGCTGCCGTTCGAAGGTGTCG
CCCCTGCGGGCCACTCTCAGGCACACACCGACCCTGTACTTGTCCTCTCCCTTCCACACACTAA
ATCAAGGGCTGCATGGCTGAGTCGAACCTCATCCCTGCCCTTTAGGATTTTGTCTCGTGGATAT
AAAACTGAACATAAGGTATTGACAAACTTAAACTGTGGGAAAGTCCCGTCATTGAGCAATGTGA
TTTTAGTAATGACAATAAAATCATGGACCTCAATTAAAAAGGTGAGGTAAATCGCTAAAC

hide sequence

RefSeq Acc Id:

XM_038430951 ⟹ XP_038286879

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	22	4,989,146 - 5,017,734 (+)	NCBI

RefSeq Acc Id:

XM_038430952 ⟹ XP_038286880

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	22	4,985,580 - 5,017,734 (+)	NCBI

RefSeq Acc Id:

XM_038430953 ⟹ XP_038286881

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	22	4,980,314 - 5,017,734 (+)	NCBI

RefSeq Acc Id:

XM_038430954 ⟹ XP_038286882

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	22	4,994,028 - 5,017,734 (+)	NCBI

RefSeq Acc Id:

XM_038456786 ⟹ XP_038312714

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	22	4,921,157 - 4,953,319 (+)	NCBI

RefSeq Acc Id:

XM_038456787 ⟹ XP_038312715

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	22	4,916,030 - 4,953,319 (+)	NCBI

RefSeq Acc Id:

XM_038506333 ⟹ XP_038362261

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	22	4,771,489 - 4,800,374 (+)	NCBI

RefSeq Acc Id:

XM_038506334 ⟹ XP_038362262

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	22	4,767,921 - 4,800,374 (+)	NCBI

RefSeq Acc Id:

XM_038506335 ⟹ XP_038362263

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	22	4,762,415 - 4,800,374 (+)	NCBI

RefSeq Acc Id:

XM_038506336 ⟹ XP_038362264

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	22	4,776,368 - 4,800,374 (+)	NCBI

RefSeq Acc Id:

XM_038569533 ⟹ XP_038425461

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	22	4,839,838 - 4,868,748 (+)	NCBI

RefSeq Acc Id:

XM_038569534 ⟹ XP_038425462

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	22	4,836,270 - 4,868,748 (+)	NCBI

RefSeq Acc Id:

XM_038569535 ⟹ XP_038425463

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	22	4,830,727 - 4,868,748 (+)	NCBI

RefSeq Acc Id:

XM_038569536 ⟹ XP_038425464

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	22	4,844,716 - 4,868,748 (+)	NCBI

RefSeq Acc Id:

XM_038633699 ⟹ XP_038489627

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	22	4,834,475 - 4,863,052 (+)	NCBI

RefSeq Acc Id:

XM_038633700 ⟹ XP_038489628

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	22	4,830,901 - 4,863,052 (+)	NCBI

RefSeq Acc Id:

XM_038633701 ⟹ XP_038489629

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	22	4,825,919 - 4,863,052 (+)	NCBI

RefSeq Acc Id:

XM_038633702 ⟹ XP_038489630

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	22	4,839,344 - 4,863,052 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_005634139	(Get FASTA)	NCBI Sequence Viewer
	XP_013961877	(Get FASTA)	NCBI Sequence Viewer
	XP_038286879	(Get FASTA)	NCBI Sequence Viewer
	XP_038286880	(Get FASTA)	NCBI Sequence Viewer
	XP_038286881	(Get FASTA)	NCBI Sequence Viewer
	XP_038286882	(Get FASTA)	NCBI Sequence Viewer
	XP_038312714	(Get FASTA)	NCBI Sequence Viewer
	XP_038312715	(Get FASTA)	NCBI Sequence Viewer
	XP_038362261	(Get FASTA)	NCBI Sequence Viewer
	XP_038362262	(Get FASTA)	NCBI Sequence Viewer
	XP_038362263	(Get FASTA)	NCBI Sequence Viewer
	XP_038362264	(Get FASTA)	NCBI Sequence Viewer
	XP_038425461	(Get FASTA)	NCBI Sequence Viewer
	XP_038425462	(Get FASTA)	NCBI Sequence Viewer
	XP_038425463	(Get FASTA)	NCBI Sequence Viewer
	XP_038425464	(Get FASTA)	NCBI Sequence Viewer
	XP_038489627	(Get FASTA)	NCBI Sequence Viewer
	XP_038489628	(Get FASTA)	NCBI Sequence Viewer
	XP_038489629	(Get FASTA)	NCBI Sequence Viewer
	XP_038489630	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00845010729.1
	ENSCAFP00845010769.1
	ENSCAFP00845010860
	ENSCAFP00845010860.1

RefSeq Acc Id:	XP_013961877 ⟸ XM_014106402
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I3N3T8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLTNNLACAHPQQETPDRNDGAVQGRTLNPFSPEAFLLPVDVEKENAHFYVADMIIAAMEKIKY AILSQQHPDPWGEEEARGAPGSGHADAETTFYSNMKQGSGSSNSSDSGYEGCAMLQGSPVAGTP TYGDVLKEACKCDFDDFVVVELGEFSNITETCGCSCSSSKSIVYEPDFNSAELIAKELYRVFQK CWMWSEVHHQLEGSPNAAGSIVVNEERVRKDFESSVDVVQEIKLQSKIREAEDWEPPRFQIIFD VHPPLKRDLVVAAQNFLCAGCGTPIEPKFVRRLRYCDYLGKYFCDCCHTYADSCIPARILSTWD FRRYYVSNFSKRLLDSVWHQPIFNLLSAGHSLYAKAKELDRAREIQEQLFQIKKLLKTCRFAES AVKAFEQVPRHLTDDLHLFSLEDLVRVKKRLLVPLLKDILKASLAHVASCELCQGKGFICEFCQ STAVIFPFQTETCRRCAGCRACFHKQCFQSSECPRCARITARRRLLESLPSAAT hide sequence

RefSeq Acc Id:	XP_005634139 ⟸ XM_005634082
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3N771 (UniProtKB/TrEMBL), A0A8C0L0Y8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MIIAAMEKIKYAILSQQHPDPWGEEEARGAPGSGHADAETTFYSNMKQGSGSSNSSDSGYEGCA MLQGSPVAGTPTYGDVLKEACKCDFDDFVVVELGEFSNITETCGCSCSSSKSIVYEPDFNSAEL IAKELYRVFQKCWMWSEVHHQLEGSPNAAGSIVVNEERVRKDFESSVDVVQEIKLQSKIREAED WEPPRFQIIFDVHPPLKRDLVVAAQNFLCAGCGTPIEPKFVRRLRYCDYLGKYFCDCCHTYADS CIPARILSTWDFRRYYVSNFSKRLLDSVWHQPIFNLLSAGHSLYAKAKELDRAREIQEQLFQIK KLLKTCRFAESAVKAFEQVPRHLTDDLHLFSLEDLVRVKKRLLVPLLKDILKASLAHVASCELC QGKGFICEFCQSTAVIFPFQTETCRRCAGCRACFHKQCFQSSECPRCARITARRRLLESLPSAA T hide sequence

Ensembl Acc Id:

ENSCAFP00000006678 ⟸ ENSCAFT00000007212

RefSeq Acc Id:	XP_038362263 ⟸ XM_038506335
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038362262 ⟸ XM_038506334
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038362261 ⟸ XM_038506333
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038362264 ⟸ XM_038506336
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038489629 ⟸ XM_038633701
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038489628 ⟸ XM_038633700
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038489627 ⟸ XM_038633699
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038489630 ⟸ XM_038633702
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038286881 ⟸ XM_038430953
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3N771 (UniProtKB/TrEMBL), A0A8C0L0Y8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038286880 ⟸ XM_038430952
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3N771 (UniProtKB/TrEMBL), A0A8C0L0Y8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038286879 ⟸ XM_038430951
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I3N3T8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038286882 ⟸ XM_038430954
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3N771 (UniProtKB/TrEMBL), A0A8C0L0Y8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038312715 ⟸ XM_038456787
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3N771 (UniProtKB/TrEMBL), A0A8C0L0Y8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038312714 ⟸ XM_038456786
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3N771 (UniProtKB/TrEMBL), A0A8C0L0Y8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038425463 ⟸ XM_038569535
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0L0Y8 (UniProtKB/TrEMBL), A0A8I3N771 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038425462 ⟸ XM_038569534
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0L0Y8 (UniProtKB/TrEMBL), A0A8I3N771 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038425461 ⟸ XM_038569533
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I3N3T8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038425464 ⟸ XM_038569536
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0L0Y8 (UniProtKB/TrEMBL), A0A8I3N771 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845010769 ⟸ ENSCAFT00845013888

Ensembl Acc Id:

ENSCAFP00845010729 ⟸ ENSCAFT00845013829

Ensembl Acc Id:

ENSCAFP00845010860 ⟸ ENSCAFT00845014012

Protein Domains

Rubicon Homology

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000004480	Ensembl
	ENSCAFG00845007831	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00845013829.1	UniProtKB/TrEMBL
	ENSCAFT00845013888.1	UniProtKB/TrEMBL
	ENSCAFT00845014012	ENTREZGENE
	ENSCAFT00845014012.1	UniProtKB/TrEMBL
InterPro	Autophagy_HostDef_Reg	UniProtKB/TrEMBL
	RUBC_PIKBD	UniProtKB/TrEMBL
	Zf-RING_9	UniProtKB/TrEMBL
KEGG Report	cfa:485452	UniProtKB/TrEMBL
NCBI Gene	RUBCNL	ENTREZGENE
PANTHER	PHOX (PX) DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
	PROTEIN ASSOCIATED WITH UVRAG AS AUTOPHAGY ENHANCER	UniProtKB/TrEMBL
Pfam	RUBC_PIKBD	UniProtKB/TrEMBL
	zf-RING_9	UniProtKB/TrEMBL
RNAcentral	URS00022B334F	RNACentral
	URS00022B6CCC	RNACentral
	URS00022B94D6	RNACentral
SMART	DUF4206	UniProtKB/TrEMBL
UniProt	A0A8C0L0Y8	ENTREZGENE
	A0A8I3MXU9_CANLF	UniProtKB/TrEMBL
	A0A8I3N3T8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3N771	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:45802	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-01-22	RUBCNL	rubicon like autophagy enhancer		rubicon like autophagy regulator	Symbol and/or name change	5135510	APPROVED
2018-12-25	RUBCNL	rubicon like autophagy regulator		RUN and cysteine rich domain containing beclin 1 interacting protein like	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar