LHX3 (LIM homeobox 3) - Rat Genome Database

Name: LHX3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: LHX3 (LIM homeobox 3) Canis lupus familiaris

Analyze

Symbol:

LHX3

Name:

LIM homeobox 3

RGD ID:

12128191

Description:

ENCODES a protein that exhibits DNA binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN cell differentiation (ortholog); dorsal/ventral pattern formation (ortholog); lung development (ortholog); ASSOCIATED WITH Adams-Oliver Syndrome 5 (ortholog); atrial fibrillation (ortholog); autosomal dominant non-syndromic intellectual disability 8 (ortholog); FOUND IN nucleus (ortholog); transcription regulator complex (ortholog)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

LIM homeodomain box protein 3; LIM/homeobox protein Lhx3

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Bonobo

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LHX3 (LIM homeobox 3)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Lhx3 (LIM homeobox protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Lhx3 (LIM homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Lhx3 (LIM homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LHX3 (LIM homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Lhx3 (LIM homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LHX3 (LIM homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	LHX3 (LIM homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Lhx3 (LIM homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	LHX4 (LIM homeobox 4)	HGNC	OrthoDB

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

NCBI Annotation Information:

Annotation category: suggests misassembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	9	49,248,621 - 49,254,118 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	9	49,248,555 - 49,254,128 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Adams-Oliver Syndrome 5 (ISO)

atrial fibrillation (ISO)

autosomal dominant non-syndromic intellectual disability 8 (ISO)

Combined Pituitary Hormone Deficiency, 1 (ISO)

Combined Pituitary Hormone Deficiency, 2 (ISO)

Combined Pituitary Hormone Deficiency, 3 (ISO)

developmental and epileptic encephalopathy 14 (ISO)

isolated growth hormone deficiency (IEA)

Kleefstra syndrome 1 (ISO)

panhypopituitarism (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell differentiation (ISO)

dorsal/ventral pattern formation (ISO)

inner ear development (IEA)

lung development (ISO)

medial motor column neuron differentiation (IEA,ISO)

motor neuron axon guidance (IEA,ISO)

negative regulation of apoptotic process (IEA,ISO)

neuron differentiation (IBA)

pituitary gland development (IEA,ISO)

placenta development (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

positive regulation of transcription, DNA-templated (ISO)

regulation of transcription by RNA polymerase II (IBA)

regulation of transcription, DNA-templated (ISO)

spinal cord association neuron differentiation (IEA,ISO)

spinal cord motor neuron cell fate specification (IEA,ISO)

ventral spinal cord interneuron specification (IEA,ISO)

Cellular Component

nucleus (IBA,ISO)

transcription regulator complex (IEA,ISO)

Molecular Function

DNA binding (ISO)

DNA-binding transcription activator activity, RNA polymerase II-specific (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

metal ion binding (IEA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IEA)

RNA polymerase II transcription factor binding (IEA)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IBA)

sequence-specific DNA binding (ISO)

References

Additional References at PubMed

PMID:22132174	PMID:25273400	PMID:25586673

Genomics

Comparative Map Data

LHX3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	9	49,248,621 - 49,254,118 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	9	49,248,555 - 49,254,128 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

LHX3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	9	136,196,250 - 136,205,128 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	9	136,196,250 - 136,205,128 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	9	139,088,096 - 139,096,974 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
GRCh37	9	139,088,096 - 139,096,955 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	138,227,917 - 138,236,776 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	9	136,314,040 - 136,322,900	NCBI
Celera	9	109,606,466 - 109,615,325 (-)	NCBI
Cytogenetic Map	9	q34.3	NCBI
HuRef	9	108,552,281 - 108,560,958 (-)	NCBI		HuRef
CHM1_1	9	139,236,859 - 139,245,738 (-)	NCBI		CHM1_1

Lhx3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	26,090,224 - 26,098,261 (-)	NCBI	GRCm39		mm39
GRCm38	2	26,200,212 - 26,208,249 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	26,200,212 - 26,208,289 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	26,055,732 - 26,062,076 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	2	26,022,956 - 26,030,258 (-)	NCBI			mm8
Celera	2	25,922,727 - 25,929,069 (-)	NCBI		Celera
Cytogenetic Map	2	A3	NCBI
cM Map	2	18.44	NCBI

Lhx3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	9,026,432 - 9,035,122 (-)	NCBI
Rnor_6.0 Ensembl	3	3,654,755 - 3,661,810 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	3	3,653,861 - 3,662,509 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	3	9,015,656 - 9,023,734 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	4,381,890 - 4,389,132 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	3	4,387,210 - 4,387,304 (-)	NCBI
Celera	3	3,849,012 - 3,855,303 (-)	NCBI		Celera
Cytogenetic Map	3	p13	NCBI

Lhx3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955513	4,464,149 - 4,470,962 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955513	4,464,149 - 4,470,962 (+)	NCBI	ChiLan1.0	ChiLan1.0

LHX3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	9	136,252,974 - 136,260,366 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	136,252,880 - 136,260,366 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	9	107,271,131 - 107,280,001 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

Lhx3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936669	1,561,433 - 1,573,074 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LHX3
(Sus scrofa - pig)

No map positions available.

LHX3
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	1,997,437 - 2,007,473 (+)	NCBI
ChlSab1.1 Ensembl	12	2,000,638 - 2,006,430 (+)	Ensembl

Lhx3
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624760	1,428,496 - 1,435,414 (-)	NCBI

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	circulatory system	endocrine system	hemolymphoid system	integumental system	musculoskeletal system	nervous system	reproductive system	adipose tissue
High
Medium		6				6
Low	1	1					2
Below cutoff		3	3	1	3	2	6	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001197187	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038675092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GQ463736	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GQ463737	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GQ913875	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000103	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000313	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSCAFT00000020228 ⟹ ENSCAFP00000018765

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	9	49,248,621 - 49,254,118 (+)	Ensembl

RefSeq Acc Id:

NM_001197187 ⟹ NP_001184116

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	9	49,248,621 - 49,254,128 (+)	NCBI

Sequence:

show sequence

GCAGCTCCCGGAGACGGGACCCATGGAGGCGCGCGGGGAGCTGGGCCCGGGCCGCGAGTCGGCG
GGTGGAGACCTGCTGCTGGCGCTGCTGGCGCGGAGGGAGGACCTACGCCGAGAGATCCCGCTGT
GCGCCGGCTGCGACCAGCACATCCTGGACCGCTTCATCCTCAAGGCACTGGACCGCCACTGGCA
CAGCAAGTGCCTCAAGTGCACGGACTGCCACACGCCCCTGGCCGAGCGTTGCTTCAGCCGCGGG
GAGAGCGTCTACTGCAAGGACGACTTCTTCAAGCGATTCGGGACCAAGTGCGCCGCGTGCCAGC
TGGGCATCCCGCCCACGCAGGTGGTGCGCCGCGCCCAGGACTTCGTGTACCACCTGCACTGCTT
CGCCTGCGTCGTGTGCAAGCGGCAGCTGGCCACAGGCGACGAGTTCTACCTCATGGAAGACAGC
CGGCTCGTGTGCAAGGCGGATTACGAGACGGCCAAGCAGCGCGAGGCGGAGGCCACGGCCAAGC
GGCCGCGCACGACCATCACGGCCAAGCAGCTGGAGACCTTGAAGAGCGCCTACAACACGTCGCC
CAAGCCGGCGCGCCACGTGCGCGAGCAGCTGTCGTCGGAGACGGGCCTGGACATGCGGGTCGTG
CAGGTGTGGTTCCAGAACCGCCGCGCCAAGGAAAAGCGGCTCAAGAAGGATGCGGGCCGGCAGC
GCTGGGGCCCGTACTTCCGCAGCATGAAGCGCGCCCGCGGCGGCCCCAAGTCGGACAAGGACAG
CGTCCAGGAGGAGGGGCAGGACAGCGACGCCGACGTCTCCTTCACGGATGAGCCGACCATGGCC
GACCTGGGCCCTGCCAACGGCCTCTACAGCAGCCTGGGGGAGCCCACCTCAGCCCTGGGCAGGC
CTGCGGGAGCCCCAGGCAGCTTCCCACTGGAGCACGGAGGCCTGGCCGGCCCGGAGCAGTACCG
TGAGCTGCGCCCCAGCAGCCCCTATGGGGTCCCCCCGTCCCCAGCTGCCCTGCAGAGCCTCCCT
GGCCCCCAGCCCCTTCTCTCTAGCTTAGTATATCCAGATGCCAGCTTGGGCCTGGTGCCCTCGG
GCACCCCAGGTGGGCCCCCACCCATGAGGGTGCTGGCCGGAAACGGACCCAGCTCCGACCTGTC
CACAGGGAGCAGTGGGGGCTACCCCGACTTCCCCGCTAGCCCCGCCTCCTGGCTGGATGAGGTT
GACCACGGCCAGTTCTGACCGAGGGCCC

hide sequence

RefSeq Acc Id:

XM_022422603 ⟹ XP_022278311

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	9	49,248,555 - 49,254,128 (+)	NCBI

Sequence:

show sequence

CCAGGAGCGCAGGGAATAACTCGGACACCAGCCTGGGGCCCCGGGAAAGTTCGGGACCCGAGAG
CCGCAGCTCCCGGAGACGGGACCCATGGAGGCGCGCGGGGAGCTGGGCCCGGGCCGCGAGTCGG
CGGGTGGAGACCTGCTGCTGGCGCTGCTGGCGCGGAGGGAGGACCTACGCCGAGAGATCCCGCT
GTGCGCCGGCTGCGACCAGCACATCCTGGACCGCTTCATCCTCAAGGCACTGGACCGCCACTGG
CACAGCAAGTGCCTCAAGTGCACGGACTGCCACACGCCCCTGGCCGAGCGTTGCTTCAGCCGCG
GGGAGAGCGTCTACTGCAAGGACGACTTCTTCAAGCGATTCGGGACCAAGTGCGCCGCGTGCCA
GCTGGGCATCCCGCCCACGCAGGTGGTGCGCCGCGCCCAGGACTTCGTGTACCACCTGCACTGC
TTCGCCTGCGTCGTGTGCAAGCGGCAGCTGGCCACAGGCGACGAGTTCTACCTCATGGAAGACA
GCCGGCTCGTGTGCAAGGCGGATTACGAGACGGCCAAGCAGCGCGAGGCGGAGGCCACGGCCAA
GCGGCCGCGCACGACCATCACGGCCAAGCAGCTGGAGACCTTGAAGAGCGCCTACAACACGTCG
CCCAAGCCGGCGCGCCACGTGCGCGAGCAGCTGTCGTCGGAGACGGGCCTGGACATGCGGGTCG
TGCAGGTGTGGTTCCAGAACCGCCGCGCCAAGGAAAAGCGGCTCAAGAAGGATGCGGGCCGGCA
GCGCTGGGGCCCGTACTTCCGCAGCATGAAGCGCGCCCGCGGCGGCCCCACAGTTGGACAAGGA
CAGCGTCCAGGAGGAGGGGCAGGACAGCGACGCCGACGTCTCCTTCACGGATGAGCCGACCATG
GCCGACCTGGGCCCTGCCAACGGCCTCTACAGCAGCCTGGGGGAGCCCACCTCAGCCCTGGGCA
GGCCTGCGGGAGCCCCAGGCAGCTTCCCACTGGAGCACGGAGGCCTGGCCGGCCCGGAGCAGTA
CCGTGAGCTGCGCCCCAGCAGCCCCTATGGGGTCCCCCCGTCCCCAGCTGCCCTGCAGAGCCTC
CCTGGCCCCCAGCCCCTTCTCTCTAGCTTAGTATATCCAGATGCCAGCTTGGGCCTGGTGCCCT
CGGGCACCCCAGGTGGGCCCCCACCCATGAGGGTGCTGGCCGGAAACGGACCCAGCTCCGACCT
GTCCACAGGGAGCAGTGGGGGCTACCCCGACTTCCCCGCTAGCCCCGCCTCCTGGCTGGATGAG
GTTGACCACGGCCAGTTCTGACCGAGGGCCC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001184116	(Get FASTA)	NCBI Sequence Viewer
	XP_038531020	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ADK38611	(Get FASTA)	NCBI Sequence Viewer
	ADK38612	(Get FASTA)	NCBI Sequence Viewer
	ADO00272	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001184116 ⟸ NM_001197187

- UniProtKB:

E0X4D7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEARGELGPGRESAGGDLLLALLARREDLRREIPLCAGCDQHILDRFILKALDRHWHSKCLKCT
DCHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKR
QLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVR
EQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGPYFRSMKRARGGPKSDKDSVQEEGQD
SDADVSFTDEPTMADLGPANGLYSSLGEPTSALGRPAGAPGSFPLEHGGLAGPEQYRELRPSSP
YGVPPSPAALQSLPGPQPLLSSLVYPDASLGLVPSGTPGGPPPMRVLAGNGPSSDLSTGSSGGY
PDFPASPASWLDEVDHGQF

hide sequence

RefSeq Acc Id:

XP_022278311 ⟸ XM_022422603

- Peptide Label:

isoform X1

- Sequence:

show sequence

MEARGELGPGRESAGGDLLLALLARREDLRREIPLCAGCDQHILDRFILKALDRHWHSKCLKCT
DCHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKR
QLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVR
EQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGPYFRSMKRARGGPTVGQGQRPGGGAG
QRRRRLLHG

hide sequence

RefSeq Acc Id:

ENSCAFP00000018765 ⟸ ENSCAFT00000020228

Protein Domains

Homeobox LIM zinc-binding

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000019695	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSCAFP00000018765	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000020228	ENTREZGENE, UniProtKB/TrEMBL
InterPro	Homeobox-like	UniProtKB/TrEMBL
	Homeobox_CS	UniProtKB/TrEMBL
	Homeobox_dom	UniProtKB/TrEMBL
	Znf_LIM	UniProtKB/TrEMBL
KEGG Report	cfa:607584	UniProtKB/TrEMBL
NCBI Gene	LHX3	ENTREZGENE
Pfam	Homeobox	UniProtKB/TrEMBL
	LIM	UniProtKB/TrEMBL
PROSITE	HOMEOBOX_1	UniProtKB/TrEMBL
	HOMEOBOX_2	UniProtKB/TrEMBL
	LIM_DOMAIN_1	UniProtKB/TrEMBL
	LIM_DOMAIN_2	UniProtKB/TrEMBL
SMART	HOX	UniProtKB/TrEMBL
	LIM	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46689	UniProtKB/TrEMBL
UniProt	E0X4D6_CANLF	UniProtKB/TrEMBL
	E0X4D7	ENTREZGENE, UniProtKB/TrEMBL
	G3BKG0_CANLF	UniProtKB/TrEMBL
	L7N0D8_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:42664	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIA

Imported Disease Annotations - OMIM