LOC100686484 (zinc finger protein 77) - Rat Genome Database

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Gene: LOC100686484 (zinc finger protein 77) Canis lupus familiaris
Analyze
Symbol: LOC100686484
Name: zinc finger protein 77
RGD ID: 12125885
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription repressor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (inferred); regulation of DNA-templated transcription (inferred); regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ZNF77
RGD Orthologs
Human
Mouse
Rat
Bonobo
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12056,209,776 - 56,231,650 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2056,006,470 - 56,028,862 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02056,942,169 - 56,964,612 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12055,986,960 - 56,018,537 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02056,480,479 - 56,502,891 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02056,680,399 - 56,702,281 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA)
nucleus  (IEA)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LOC100686484
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12056,209,776 - 56,231,650 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2056,006,470 - 56,028,862 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02056,942,169 - 56,964,612 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12055,986,960 - 56,018,537 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02056,480,479 - 56,502,891 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02056,680,399 - 56,702,281 (+)NCBIUU_Cfam_GSD_1.0
ZNF77
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38192,933,218 - 2,950,625 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl192,933,218 - 2,944,971 (-)EnsemblGRCh38hg38GRCh38
GRCh37192,933,216 - 2,944,969 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36192,884,216 - 2,895,930 (-)NCBINCBI36Build 36hg18NCBI36
Build 34192,884,216 - 2,895,930NCBI
Celera192,867,356 - 2,879,033 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef192,701,465 - 2,713,143 (-)NCBIHuRef
CHM1_1192,932,811 - 2,944,556 (-)NCBICHM1_1
T2T-CHM13v2.0192,906,814 - 2,918,459 (-)NCBIT2T-CHM13v2.0
2010315B03Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399124,054,432 - 124,075,349 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9124,054,434 - 124,075,326 (-)EnsemblGRCm39 Ensembl
GRCm389124,291,802 - 124,312,719 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9124,291,804 - 124,312,696 (-)EnsemblGRCm38mm10GRCm38
Celera9124,799,557 - 124,820,106 (-)NCBICelera
Cytogenetic Map9F4NCBI
Znf57l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr878,688,422 - 8,712,170 (-)NCBIGRCr8
mRatBN7.278,037,649 - 8,060,640 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,037,652 - 8,060,035 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx710,924,214 - 10,946,485 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0712,799,878 - 12,822,149 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0710,662,089 - 10,689,359 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0710,893,763 - 10,916,685 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl710,498,064 - 10,500,392 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl710,894,119 - 10,896,447 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0711,063,248 - 11,086,179 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.479,510,066 - 9,532,434 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera76,228,621 - 6,251,007 (-)NCBICelera
Cytogenetic Map7q11NCBI
ZNF77
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2207,328,402 - 7,346,063 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1196,557,804 - 6,574,697 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0191,958,391 - 1,970,374 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1192,910,461 - 2,921,590 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl192,910,461 - 2,921,590 (-)Ensemblpanpan1.1panPan2
LOC101964124
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118216,139,337 - 216,147,086 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365881,685,787 - 1,692,596 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365881,688,566 - 1,694,900 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100516355
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl275,742,827 - 75,767,708 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1275,742,538 - 75,767,725 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2276,166,770 - 76,212,412 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF77
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.162,709,670 - 2,719,315 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660815,866,797 - 5,881,744 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in LOC100686484
431 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 4 4
Low 4 5 18 2 6 2 6 6 12 8 10 6
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005633088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005633089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022407256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022407257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038429199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038429200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038504736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038504737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038504738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038567872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038567873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038567874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038631996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038631997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005633088   ⟹   XP_005633145
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12056,209,776 - 56,231,650 (+)NCBI
Dog10K_Boxer_Tasha2056,006,470 - 56,028,862 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005633089   ⟹   XP_005633146
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12056,209,776 - 56,231,650 (+)NCBI
Dog10K_Boxer_Tasha2056,006,475 - 56,028,862 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038429199   ⟹   XP_038285127
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02056,942,169 - 56,964,612 (+)NCBI
RefSeq Acc Id: XM_038429200   ⟹   XP_038285128
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02056,942,175 - 56,964,612 (+)NCBI
RefSeq Acc Id: XM_038504736   ⟹   XP_038360664
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12055,986,960 - 56,018,537 (+)NCBI
RefSeq Acc Id: XM_038504737   ⟹   XP_038360665
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12055,986,960 - 56,018,537 (+)NCBI
RefSeq Acc Id: XM_038504738   ⟹   XP_038360666
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12055,986,963 - 56,018,537 (+)NCBI
RefSeq Acc Id: XM_038567872   ⟹   XP_038423800
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02056,680,416 - 56,702,281 (+)NCBI
RefSeq Acc Id: XM_038567873   ⟹   XP_038423801
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02056,680,399 - 56,702,281 (+)NCBI
RefSeq Acc Id: XM_038567874   ⟹   XP_038423802
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02056,690,565 - 56,702,281 (+)NCBI
RefSeq Acc Id: XM_038631996   ⟹   XP_038487924
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02056,480,479 - 56,502,891 (+)NCBI
RefSeq Acc Id: XM_038631997   ⟹   XP_038487925
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02056,480,485 - 56,502,891 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005633145   ⟸   XM_005633088
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005633146   ⟸   XM_005633089
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_038360665   ⟸   XM_038504737
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038360664   ⟸   XM_038504736
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038360666   ⟸   XM_038504738
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038487924   ⟸   XM_038631996
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038487925   ⟸   XM_038631997
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038285127   ⟸   XM_038429199
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038285128   ⟸   XM_038429200
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038423801   ⟸   XM_038567873
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038423800   ⟸   XM_038567872
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038423802   ⟸   XM_038567874
- Peptide Label: isoform X5
Protein Domains
C2H2-type   KRAB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000031469 UniProtKB/TrEMBL
  ENSCAFG00845011169 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000049840.3 UniProtKB/TrEMBL
  ENSCAFT00845019795.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene LOC100686484 ENTREZGENE
PANTHER NOVEL KRAB BOX AND ZINC FINGER, C2H2 TYPE DOMAIN CONTAINING PROTEIN-RELATED UniProtKB/TrEMBL
  ZINC FINGER AND BTB DOMAIN-CONTAINING UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
  zf-C2H2_4 UniProtKB/TrEMBL
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A8I3NE32_CANLF UniProtKB/TrEMBL
  A0A8P0NQP1_CANLF UniProtKB/TrEMBL