SLC30A2 (solute carrier family 30 member 2) - Rat Genome Database

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Gene: SLC30A2 (solute carrier family 30 member 2) Canis lupus familiaris
Analyze
Symbol: SLC30A2
Name: solute carrier family 30 member 2
RGD ID: 12123016
Description: ENCODES a protein that exhibits identical protein binding (ortholog); zinc ion transmembrane transporter activity (ortholog); zinc:proton antiporter activity (ortholog); INVOLVED IN intracellular zinc ion homeostasis (ortholog); zinc export across plasma membrane (ortholog); zinc ion import into lysosome (ortholog); ASSOCIATED WITH autosomal recessive hypercholesterolemia (ortholog); genetic disease (ortholog); Neonatal Zinc Deficiency due to Low Breast Milk Zinc (ortholog); FOUND IN cytoplasm (ortholog); endosome membrane (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: zinc transporter 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1273,922,443 - 73,929,924 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl273,921,878 - 73,928,874 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha270,498,812 - 70,506,207 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,485,426 - 74,492,825 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,484,778 - 74,491,775 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1271,309,034 - 71,316,428 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0272,315,360 - 72,322,755 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0273,319,147 - 73,326,547 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SLC30A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1273,922,443 - 73,929,924 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl273,921,878 - 73,928,874 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha270,498,812 - 70,506,207 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,485,426 - 74,492,825 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,484,778 - 74,491,775 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1271,309,034 - 71,316,428 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0272,315,360 - 72,322,755 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0273,319,147 - 73,326,547 (+)NCBIUU_Cfam_GSD_1.0
SLC30A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,037,252 - 26,046,118 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl126,037,252 - 26,046,118 (-)EnsemblGRCh38hg38GRCh38
GRCh37126,363,743 - 26,372,609 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,237,101 - 26,245,191 (-)NCBINCBI36Build 36hg18NCBI36
Build 34126,048,655 - 26,056,746NCBI
Celera124,761,192 - 24,769,282 (-)NCBICelera
Cytogenetic Map1p36.11NCBI
HuRef124,618,624 - 24,626,717 (-)NCBIHuRef
CHM1_1126,477,743 - 26,485,833 (-)NCBICHM1_1
T2T-CHM13v2.0125,874,654 - 25,883,519 (-)NCBIT2T-CHM13v2.0
Slc30a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394134,070,357 - 134,081,795 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4134,070,492 - 134,081,795 (+)EnsemblGRCm39 Ensembl
GRCm384134,343,046 - 134,354,484 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4134,343,181 - 134,354,484 (+)EnsemblGRCm38mm10GRCm38
MGSCv374133,898,985 - 133,908,580 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364133,615,122 - 133,625,270 (+)NCBIMGSCv36mm8
MGSCv364131,918,527 - 131,928,675 (+)NCBIMGSCv36mm8
Celera4132,522,807 - 132,532,421 (+)NCBICelera
Cytogenetic Map4D2.3NCBI
cM Map466.61NCBI
Slc30a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85151,843,451 - 151,855,674 (+)NCBIGRCr8
mRatBN7.25146,559,733 - 146,571,957 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5146,559,733 - 146,571,956 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5149,261,093 - 149,273,806 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05151,031,874 - 151,044,095 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05151,017,317 - 151,030,034 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05152,559,577 - 152,571,800 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5152,559,577 - 152,571,799 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05156,356,502 - 156,368,725 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45153,086,346 - 153,098,569 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15153,097,114 - 153,107,129 (+)NCBI
Celera5144,977,168 - 144,989,389 (+)NCBICelera
Cytogenetic Map5q36NCBI
Slc30a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554525,504,022 - 5,516,246 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554525,507,614 - 5,515,669 (-)NCBIChiLan1.0ChiLan1.0
SLC30A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21200,828,094 - 200,836,275 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11199,926,146 - 199,934,081 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0125,296,643 - 25,304,751 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1126,362,678 - 26,370,803 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,359,575 - 26,370,803 (-)Ensemblpanpan1.1panPan2
Slc30a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505844,756,722 - 44,764,976 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647410,581,480 - 10,589,442 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647410,581,504 - 10,589,364 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC30A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl683,477,759 - 83,484,688 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1683,478,761 - 83,484,876 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2677,113,410 - 77,122,493 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC30A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120106,722,539 - 106,731,494 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20106,724,256 - 106,731,955 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660339,686,150 - 9,695,043 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc30a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476410,110,740 - 10,120,093 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476410,104,622 - 10,119,953 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC30A2
87 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 10 5
Low 4 2 1 1 7 8 5
Below cutoff 1 5 10 5 6 5 6 6 5 6

Sequence


RefSeq Acc Id: ENSCAFT00000020143   ⟹   ENSCAFP00000018683
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl273,922,520 - 73,928,874 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000048920   ⟹   ENSCAFP00000039147
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl273,921,878 - 73,927,167 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000068271   ⟹   ENSCAFP00000056768
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl273,922,520 - 73,928,874 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845023569   ⟹   ENSCAFP00845018505
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl274,484,778 - 74,490,068 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845023595   ⟹   ENSCAFP00845018518
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl274,485,420 - 74,491,775 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845023631   ⟹   ENSCAFP00845018548
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl274,485,420 - 74,491,775 (+)Ensembl
RefSeq Acc Id: XM_038470646   ⟹   XP_038326574
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1271,309,034 - 71,316,428 (+)NCBI
RefSeq Acc Id: XM_038531507   ⟹   XP_038387435
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0273,319,147 - 73,326,547 (+)NCBI
RefSeq Acc Id: XM_038595727   ⟹   XP_038451655
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0272,315,360 - 72,322,755 (+)NCBI
RefSeq Acc Id: XM_038659811   ⟹   XP_038515739
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0274,485,426 - 74,492,825 (+)NCBI
RefSeq Acc Id: XM_535347   ⟹   XP_535347
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1273,922,443 - 73,929,924 (+)NCBI
Dog10K_Boxer_Tasha270,498,812 - 70,506,207 (+)NCBI
Sequence:
RefSeq Acc Id: XP_535347   ⟸   XM_535347
- UniProtKB: A0A8C0NJA6 (UniProtKB/TrEMBL),   A0A8C0R559 (UniProtKB/TrEMBL),   A0A8I3NLD3 (UniProtKB/TrEMBL),   A0A8C0LAC9 (UniProtKB/TrEMBL),   A0A8C0QA92 (UniProtKB/TrEMBL),   A0A8I3NPH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000039147   ⟸   ENSCAFT00000048920
RefSeq Acc Id: ENSCAFP00000056768   ⟸   ENSCAFT00000068271
RefSeq Acc Id: ENSCAFP00000018683   ⟸   ENSCAFT00000020143
RefSeq Acc Id: XP_038326574   ⟸   XM_038470646
RefSeq Acc Id: XP_038451655   ⟸   XM_038595727
RefSeq Acc Id: XP_038515739   ⟸   XM_038659811
- UniProtKB: A0A8C0NJA6 (UniProtKB/TrEMBL),   A0A8C0R559 (UniProtKB/TrEMBL),   A0A8I3NLD3 (UniProtKB/TrEMBL),   A0A8C0LAC9 (UniProtKB/TrEMBL),   A0A8C0QA92 (UniProtKB/TrEMBL),   A0A8I3NPH7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038387435   ⟸   XM_038531507
- UniProtKB: A0A8C0LAC9 (UniProtKB/TrEMBL),   A0A8C0QA92 (UniProtKB/TrEMBL),   A0A8I3NPH7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845018505   ⟸   ENSCAFT00845023569
RefSeq Acc Id: ENSCAFP00845018518   ⟸   ENSCAFT00845023595
RefSeq Acc Id: ENSCAFP00845018548   ⟸   ENSCAFT00845023631

Promoters
RGD ID:13682593
Promoter ID:EPDNEW_C660
Type:single initiation site
Name:SLC30A2_1
Description:solute carrier family 30 member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1273,922,545 - 73,922,605EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000012702 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030015814 UniProtKB/TrEMBL
  ENSCAFG00040005653 UniProtKB/TrEMBL
  ENSCAFG00845013235 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000020143.5 UniProtKB/TrEMBL
  ENSCAFT00000048920.3 UniProtKB/TrEMBL
  ENSCAFT00000068271.2 UniProtKB/TrEMBL
  ENSCAFT00030029142.1 UniProtKB/TrEMBL
  ENSCAFT00030029220.1 UniProtKB/TrEMBL
  ENSCAFT00040010663.1 UniProtKB/TrEMBL
  ENSCAFT00845023569.1 UniProtKB/TrEMBL
  ENSCAFT00845023595 ENTREZGENE
  ENSCAFT00845023595.1 UniProtKB/TrEMBL
  ENSCAFT00845023631.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1510.10 UniProtKB/TrEMBL
InterPro Cation_efflux UniProtKB/TrEMBL
  Cation_efflux_CTD_sf UniProtKB/TrEMBL
  Cation_efflux_TMD_sf UniProtKB/TrEMBL
KEGG Report cfa:478173 UniProtKB/TrEMBL
NCBI Gene SLC30A2 ENTREZGENE
PANTHER CATION EFFLUX PROTEIN/ ZINC TRANSPORTER UniProtKB/TrEMBL
  ZINC TRANSPORTER 2 UniProtKB/TrEMBL
Pfam Cation_efflux UniProtKB/TrEMBL
Superfamily-SCOP SSF160240 UniProtKB/TrEMBL
  SSF161111 UniProtKB/TrEMBL
UniProt A0A8C0LAC9 ENTREZGENE
  A0A8C0NJA6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0QA92 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0R559 ENTREZGENE
  A0A8I3NLD3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NNZ6_CANLF UniProtKB/TrEMBL
  A0A8I3NPH7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0STG4_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:46347 ENTREZGENE