SFT2D2 (SFT2 domain containing 2) - Rat Genome Database

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Gene: SFT2D2 (SFT2 domain containing 2) Canis lupus familiaris
Analyze
Symbol: SFT2D2 (Ensembl: TBX19)
Name: SFT2 domain containing 2 (Ensembl:T-box transcription factor 19)
RGD ID: 12121678
Description: ENCODES a protein that exhibits chemokine activity (inferred); cis-regulatory region sequence-specific DNA binding (inferred); cytokine activity (inferred); INVOLVED IN cell fate commitment (inferred); cell fate specification (inferred); chemotaxis (inferred); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); immunodeficiency 25 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); endomembrane system (inferred); INTERACTS WITH masitinib
Type: protein-coding
RefSeq Status: MODEL
Previously known as: vesicle transport protein SFT2B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1730,258,748 - 30,281,371 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha729,797,597 - 29,813,233 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0730,082,139 - 30,099,569 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl729,804,955 - 30,156,563 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1729,922,225 - 29,939,533 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0729,953,325 - 29,968,937 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0730,191,659 - 30,207,396 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
masitinib  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SFT2D2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1730,258,748 - 30,281,371 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha729,797,597 - 29,813,233 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0730,082,139 - 30,099,569 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl729,804,955 - 30,156,563 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1729,922,225 - 29,939,533 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0729,953,325 - 29,968,937 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0730,191,659 - 30,207,396 (-)NCBIUU_Cfam_GSD_1.0
SFT2D2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381168,226,004 - 168,253,021 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1168,225,938 - 168,253,021 (+)EnsemblGRCh38hg38GRCh38
GRCh371168,195,242 - 168,222,259 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361166,461,870 - 166,479,002 (+)NCBINCBI36Build 36hg18NCBI36
Celera1141,304,278 - 141,321,113 (+)NCBICelera
Cytogenetic Map1q24.2NCBI
HuRef1139,439,083 - 139,455,917 (+)NCBIHuRef
CHM1_11169,617,554 - 169,634,389 (+)NCBICHM1_1
T2T-CHM13v2.01167,577,504 - 167,604,523 (+)NCBIT2T-CHM13v2.0
Sft2d2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391165,001,910 - 165,022,104 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1165,001,906 - 165,022,007 (-)EnsemblGRCm39 Ensembl
GRCm381165,174,341 - 165,194,522 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1165,174,337 - 165,194,438 (-)EnsemblGRCm38mm10GRCm38
MGSCv371167,104,472 - 167,124,564 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361167,011,172 - 167,030,995 (-)NCBIMGSCv36mm8
Celera1167,612,932 - 167,633,027 (-)NCBICelera
Cytogenetic Map1H2.2NCBI
cM Map172.51NCBI
Sft2d2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81380,017,854 - 80,037,144 (-)NCBIGRCr8
mRatBN7.21377,484,778 - 77,504,123 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1377,484,636 - 77,504,112 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1380,099,288 - 80,118,578 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01381,403,299 - 81,422,589 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01378,647,715 - 78,667,012 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01383,438,635 - 83,457,899 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1383,438,493 - 83,457,888 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01388,318,211 - 88,337,483 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41380,925,172 - 80,946,239 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11380,943,908 - 80,960,416 (-)NCBI
Celera1377,197,938 - 77,217,101 (-)NCBICelera
Cytogenetic Map13q23NCBI
Sft2d2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554628,878,393 - 8,897,523 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554628,878,387 - 8,897,523 (-)NCBIChiLan1.0ChiLan1.0
SFT2D2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2181,451,726 - 81,540,228 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1181,120,555 - 81,210,884 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01143,711,788 - 143,800,206 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11147,437,627 - 147,526,156 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1147,437,627 - 147,454,541 (+)Ensemblpanpan1.1panPan2
Sft2d2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344100,178,647 - 100,193,585 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648118,027,427 - 18,039,149 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648118,025,396 - 18,039,191 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SFT2D2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl482,712,897 - 82,734,487 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1482,718,342 - 82,734,432 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2490,392,453 - 90,408,544 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SFT2D2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12560,803,531 - 60,820,507 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2560,803,725 - 60,820,038 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605562,527,161 - 62,544,378 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sft2d2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248266,208,579 - 6,226,795 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248266,208,580 - 6,226,795 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SFT2D2
329 total Variants

Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_038481260   ⟹   XP_038337188
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1729,922,225 - 29,939,533 (-)NCBI
RefSeq Acc Id: XM_038481261   ⟹   XP_038337189
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1729,922,225 - 29,937,823 (-)NCBI
RefSeq Acc Id: XM_038542617   ⟹   XP_038398545
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0730,191,659 - 30,207,396 (-)NCBI
RefSeq Acc Id: XM_038567420   ⟹   XP_038423348
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha729,797,597 - 29,813,233 (-)NCBI
RefSeq Acc Id: XM_038606771   ⟹   XP_038462699
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0729,953,325 - 29,968,937 (-)NCBI
RefSeq Acc Id: XM_038671444   ⟹   XP_038527372
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0730,082,139 - 30,099,569 (-)NCBI
RefSeq Acc Id: XM_038671445   ⟹   XP_038527373
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0730,082,139 - 30,097,865 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_038337188   ⟸   XM_038481260
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038337189   ⟸   XM_038481261
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038462699   ⟸   XM_038606771
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038527372   ⟸   XM_038671444
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038527373   ⟸   XM_038671445
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PQG3 (UniProtKB/TrEMBL),   A0A8I3RQX2 (UniProtKB/TrEMBL),   A0A8C0R650 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038423348   ⟸   XM_038567420
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PQG3 (UniProtKB/TrEMBL),   A0A8I3RQX2 (UniProtKB/TrEMBL),   A0A8C0R650 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038398545   ⟸   XM_038542617
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PQG3 (UniProtKB/TrEMBL),   A0A8C0R650 (UniProtKB/TrEMBL),   A0A8I3RQX2 (UniProtKB/TrEMBL)
Protein Domains
Chemokine interleukin-8-like   T-box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000015268 UniProtKB/TrEMBL
  ENSCAFG00030023780 UniProtKB/TrEMBL
  ENSCAFG00845002647 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000100042.1 UniProtKB/TrEMBL
  ENSCAFT00030044057.1 UniProtKB/TrEMBL
  ENSCAFT00845004702.1 UniProtKB/TrEMBL
  ENSCAFT00845004739.1 UniProtKB/TrEMBL
  ENSCAFT00845004753.1 UniProtKB/TrEMBL
  ENSCAFT00845004774.1 UniProtKB/TrEMBL
  ENSCAFT00845004822.1 UniProtKB/TrEMBL
  ENSCAFT00845004845.1 UniProtKB/TrEMBL
  ENSCAFT00845004872 ENTREZGENE
  ENSCAFT00845004872.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.40 UniProtKB/TrEMBL
  2.60.40.820 UniProtKB/TrEMBL
InterPro Chemokine_b/g/d UniProtKB/TrEMBL
  Chemokine_IL8-like_dom UniProtKB/TrEMBL
  Chemokine_XCL1/XCL2 UniProtKB/TrEMBL
  Interleukin_8-like_sf UniProtKB/TrEMBL
  p53-like_TF_DNA-bd UniProtKB/TrEMBL
  T-box_DNA-bd UniProtKB/TrEMBL
  T-box_sf UniProtKB/TrEMBL
  TF_Brachyury UniProtKB/TrEMBL
  TF_T-box UniProtKB/TrEMBL
  TF_T-box_CS UniProtKB/TrEMBL
  TIP41-like UniProtKB/TrEMBL
  Vesicle_transpt_Got1/SFT2 UniProtKB/TrEMBL
  Vesicle_transpt_SFT2 UniProtKB/TrEMBL
NCBI Gene SFT2D2 ENTREZGENE
PANTHER GAF/PUTATIVE CYTOSKELETAL PROTEIN UniProtKB/TrEMBL
  PTHR11267 UniProtKB/TrEMBL
  PTHR12015 UniProtKB/TrEMBL
  PTHR12015:SF101 UniProtKB/TrEMBL
  PTHR21021:SF16 UniProtKB/TrEMBL
  PTHR23137 UniProtKB/TrEMBL
  T-BOX TRANSCRIPTION FACTOR TBX19 UniProtKB/TrEMBL
  VESICLE TRANSPORT PROTEIN SFT2B UniProtKB/TrEMBL
Pfam Got1 UniProtKB/TrEMBL
  IL8 UniProtKB/TrEMBL
  T-box UniProtKB/TrEMBL
  TIP41 UniProtKB/TrEMBL
PRINTS BRACHYURY UniProtKB/TrEMBL
  LYMPHOTACTIN UniProtKB/TrEMBL
  TBOX UniProtKB/TrEMBL
PROSITE TBOX_1 UniProtKB/TrEMBL
  TBOX_2 UniProtKB/TrEMBL
  TBOX_3 UniProtKB/TrEMBL
SMART SCY UniProtKB/TrEMBL
  TBOX UniProtKB/TrEMBL
Superfamily-SCOP SSF49417 UniProtKB/TrEMBL
  SSF54117 UniProtKB/TrEMBL
UniProt A0A8C0PQG3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0R650 ENTREZGENE
  A0A8I3MFY8_CANLF UniProtKB/TrEMBL
  A0A8I3MJT8_CANLF UniProtKB/TrEMBL
  A0A8I3MJZ3_CANLF UniProtKB/TrEMBL
  A0A8I3MLK4_CANLF UniProtKB/TrEMBL
  A0A8I3N2Z2_CANLF UniProtKB/TrEMBL
  A0A8I3N320_CANLF UniProtKB/TrEMBL
  A0A8I3RQX2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:53831 ENTREZGENE