OR4N2B (olfactory receptor family 4 subfamily N member 2B) - Rat Genome Database

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Gene: OR4N2B (olfactory receptor family 4 subfamily N member 2B) Canis lupus familiaris
Analyze
Symbol: OR4N2B
Name: olfactory receptor family 4 subfamily N member 2B
RGD ID: 12121476
Description: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: LOC482537; olfactory receptor 4N4
RGD Orthologs
Human
Mouse
Rat
Pig
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11517,248,135 - 17,249,061 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1517,248,135 - 17,249,061 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1517,711,912 - 17,712,838 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01517,505,492 - 17,506,418 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1517,505,492 - 17,506,418 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11517,191,361 - 17,192,287 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01517,246,667 - 17,247,593 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01517,371,312 - 17,372,238 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
OR4N2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11517,248,135 - 17,249,061 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1517,248,135 - 17,249,061 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1517,711,912 - 17,712,838 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01517,505,492 - 17,506,418 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1517,505,492 - 17,506,418 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11517,191,361 - 17,192,287 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01517,246,667 - 17,247,593 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01517,371,312 - 17,372,238 (-)NCBIUU_Cfam_GSD_1.0
OR4N4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381522,094,522 - 22,095,862 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1522,094,522 - 22,095,862 (+)EnsemblGRCh38hg38GRCh38
GRCh371522,382,473 - 22,383,813 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361519,883,837 - 19,884,787 (+)NCBINCBI36Build 36hg18NCBI36
Build 341519,883,836 - 19,884,787NCBI
Celera15246,446 - 247,396 (-)NCBICelera
Cytogenetic Map15q11.2NCBI
HuRef15783,093 - 784,435 (+)NCBIHuRef
CHM1_11522,324,624 - 22,325,965 (+)NCBICHM1_1
T2T-CHM13v2.01519,000,207 - 19,001,547 (+)NCBIT2T-CHM13v2.0
Or4n4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391450,518,685 - 50,519,728 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1450,515,930 - 50,521,663 (-)EnsemblGRCm39 Ensembl
GRCm381450,281,228 - 50,282,271 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1450,278,473 - 50,284,206 (-)EnsemblGRCm38mm10GRCm38
MGSCv371450,900,903 - 50,901,946 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361449,203,276 - 49,204,202 (-)NCBIMGSCv36mm8
Celera1446,515,083 - 46,516,126 (-)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1426.03NCBI
Or4n4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81525,968,149 - 25,969,140 (+)NCBIGRCr8
mRatBN7.21523,494,563 - 23,495,554 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1523,492,445 - 23,498,563 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01527,076,234 - 27,077,198 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1527,076,234 - 27,077,160 (-)EnsemblRnor6.0rn6Rnor6.0
RGSC_v3.41526,020,147 - 26,022,189 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11526,035,846 - 26,036,755 (+)NCBI
Celera1523,826,467 - 23,827,527 (+)NCBICelera
Cytogenetic Map15p14NCBI
LOC100157798
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1779,003,689 - 79,004,969 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27133,543,058 - 133,543,984 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in OR4N2B
9 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

reproductive system
High
Medium
Low
Below cutoff 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000038257   ⟹   ENSCAFP00000033945
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1517,248,135 - 17,249,061 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845036329   ⟹   ENSCAFP00845028434
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1517,505,492 - 17,506,418 (-)Ensembl
RefSeq Acc Id: NM_001388552   ⟹   NP_001375481
RefSeq Status: INFERRED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1517,711,912 - 17,712,838 (-)NCBI
ROS_Cfam_1.01517,505,492 - 17,506,418 (-)NCBI
UMICH_Zoey_3.11517,191,361 - 17,192,287 (-)NCBI
UNSW_CanFamBas_1.01517,246,667 - 17,247,593 (-)NCBI
UU_Cfam_GSD_1.01517,371,312 - 17,372,238 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001375481 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00030015917.1
  ENSCAFP00040013443.1
  ENSCAFP00845028434
  ENSCAFP00845028434.1
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000033945   ⟸   ENSCAFT00000038257
RefSeq Acc Id: NP_001375481   ⟸   NM_001388552
- UniProtKB: A0A8C0KYZ8 (UniProtKB/TrEMBL),   A0A8I3PKF1 (UniProtKB/TrEMBL),   A0A8C0QHY5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845028434   ⟸   ENSCAFT00845036329
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000030818 Ensembl
  ENSCAFG00030009860 UniProtKB/TrEMBL
  ENSCAFG00040008293 UniProtKB/TrEMBL
  ENSCAFG00845020615 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030018226.1 UniProtKB/TrEMBL
  ENSCAFT00040015505.1 UniProtKB/TrEMBL
  ENSCAFT00845036329 ENTREZGENE
  ENSCAFT00845036329.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
NCBI Gene LOC482537 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR-RELATED UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8C0KYZ8 ENTREZGENE
  A0A8C0QHY5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RGR4_CANLF UniProtKB/TrEMBL
  A0A8I3PKF1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:84832 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-01-21 OR4N2B  olfactory receptor family 4 subfamily N member 2B  LOC482537  olfactory receptor 4N4  Symbol and/or name change 5135510 APPROVED