CENPW (centromere protein W) - Rat Genome Database

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Gene: CENPW (centromere protein W) Canis lupus familiaris
Analyze
Symbol: CENPW
Name: centromere protein W
RGD ID: 12120025
Description: ENCODES a protein that exhibits DNA binding (inferred); protein heterodimerization activity (inferred); INVOLVED IN chromosome organization (inferred); chromosome segregation (inferred); kinetochore assembly (inferred); ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); hepatocellular carcinoma (ortholog); FOUND IN inner kinetochore (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1165,171,785 - 65,178,357 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl165,171,779 - 65,178,559 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha165,981,852 - 65,988,380 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0165,376,516 - 65,383,049 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl165,376,496 - 65,384,045 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1165,309,887 - 65,316,418 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0165,092,158 - 65,098,687 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0165,742,531 - 65,749,064 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CENPW
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1165,171,785 - 65,178,357 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl165,171,779 - 65,178,559 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha165,981,852 - 65,988,380 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0165,376,516 - 65,383,049 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl165,376,496 - 65,384,045 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1165,309,887 - 65,316,418 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0165,092,158 - 65,098,687 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0165,742,531 - 65,749,064 (+)NCBIUU_Cfam_GSD_1.0
CENPW
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386126,340,115 - 126,483,320 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6126,340,115 - 126,348,875 (+)EnsemblGRCh38hg38GRCh38
GRCh376126,661,261 - 126,804,466 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366126,702,963 - 126,711,441 (+)NCBINCBI36Build 36hg18NCBI36
Build 346126,702,945 - 126,711,445NCBI
Celera6127,403,569 - 127,412,070 (+)NCBICelera
Cytogenetic Map6q22.32NCBI
HuRef6124,237,375 - 124,245,881 (+)NCBIHuRef
CHM1_16126,924,923 - 126,933,429 (+)NCBICHM1_1
T2T-CHM13v2.06127,528,692 - 127,671,944 (+)NCBIT2T-CHM13v2.0
Cenpw
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391030,072,005 - 30,076,599 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1030,070,565 - 30,076,556 (-)EnsemblGRCm39 Ensembl
GRCm381030,196,009 - 30,200,603 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1030,194,569 - 30,200,560 (-)EnsemblGRCm38mm10GRCm38
MGSCv371029,915,815 - 29,920,346 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361029,885,425 - 29,889,956 (-)NCBIMGSCv36mm8
Celera1031,122,440 - 31,126,971 (-)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1016.93NCBI
Cenpw
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8129,353,939 - 29,359,109 (+)NCBIGRCr8
mRatBN7.2127,525,324 - 27,530,464 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl127,525,324 - 27,530,464 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx127,285,514 - 27,290,660 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0133,285,372 - 33,290,518 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0127,486,121 - 27,491,267 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0129,915,443 - 29,920,598 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl129,915,443 - 29,920,598 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0131,347,827 - 31,352,722 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4128,268,281 - 28,273,220 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera126,205,053 - 26,210,285 (+)NCBICelera
Cytogenetic Map1p11NCBI
Cenpw
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554367,557,251 - 7,566,443 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554367,557,595 - 7,563,238 (+)NCBIChiLan1.0ChiLan1.0
CENPW
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25146,331,679 - 146,340,198 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16144,236,946 - 144,245,466 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06124,125,492 - 124,272,450 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16128,242,724 - 128,389,393 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6128,242,724 - 128,251,528 (+)Ensemblpanpan1.1panPan2
Cenpw
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946115,234,715 - 115,245,668 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366393,173,385 - 3,184,454 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366393,173,832 - 3,184,439 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CENPW
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl136,685,265 - 36,695,955 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1136,405,693 - 36,695,989 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2140,188,401 - 40,469,177 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CENPW
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11347,363,726 - 47,372,472 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1347,363,717 - 47,372,164 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604019,661,285 - 19,669,738 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cenpw
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624753887,689 - 896,931 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624753888,495 - 896,617 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CENPW
58 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 8
Low 5 4 18 2 6 2 6 12 10 6
Below cutoff 1 4 4 4 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000048492   ⟹   ENSCAFP00000040645
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl165,171,779 - 65,178,559 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845000501   ⟹   ENSCAFP00845000343
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl165,376,496 - 65,384,045 (+)Ensembl
RefSeq Acc Id: XM_003638784   ⟹   XP_003638832
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1165,171,785 - 65,178,357 (+)NCBI
Dog10K_Boxer_Tasha165,981,852 - 65,988,380 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038466047   ⟹   XP_038321975
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1165,309,887 - 65,316,418 (+)NCBI
RefSeq Acc Id: XM_038526731   ⟹   XP_038382659
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0165,742,531 - 65,749,064 (+)NCBI
RefSeq Acc Id: XM_038591029   ⟹   XP_038446957
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0165,092,158 - 65,098,687 (+)NCBI
RefSeq Acc Id: XM_038654827   ⟹   XP_038510755
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0165,376,516 - 65,383,049 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003638832   ⟸   XM_003638784
- UniProtKB: A0A8C0L738 (UniProtKB/TrEMBL),   A0A8C0Q256 (UniProtKB/TrEMBL),   A0A8I3RQR0 (UniProtKB/TrEMBL),   A0A8C0MT46 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000040645   ⟸   ENSCAFT00000048492
RefSeq Acc Id: XP_038321975   ⟸   XM_038466047
RefSeq Acc Id: XP_038446957   ⟸   XM_038591029
RefSeq Acc Id: XP_038510755   ⟸   XM_038654827
- UniProtKB: A0A8C0L738 (UniProtKB/TrEMBL),   A0A8C0Q256 (UniProtKB/TrEMBL),   A0A8I3RQR0 (UniProtKB/TrEMBL),   A0A8C0MT46 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038382659   ⟸   XM_038526731
- UniProtKB: A0A8C0L738 (UniProtKB/TrEMBL),   A0A8C0MT46 (UniProtKB/TrEMBL),   A0A8C0Q256 (UniProtKB/TrEMBL),   A0A8I3RQR0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845000343   ⟸   ENSCAFT00845000501


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000029836 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030008946 UniProtKB/TrEMBL
  ENSCAFG00040001471 UniProtKB/TrEMBL
  ENSCAFG00845000327 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000048492.3 UniProtKB/TrEMBL
  ENSCAFT00030016535.1 UniProtKB/TrEMBL
  ENSCAFT00040002803.1 UniProtKB/TrEMBL
  ENSCAFT00845000501 ENTREZGENE
  ENSCAFT00845000501.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.20.10 UniProtKB/TrEMBL
InterPro CENP-W UniProtKB/TrEMBL
  Histone-fold UniProtKB/TrEMBL
KEGG Report cfa:100855910 UniProtKB/TrEMBL
NCBI Gene CENPW ENTREZGENE
PANTHER CENTROMERE PROTEIN W UniProtKB/TrEMBL
  CENTROMERE PROTEIN W UniProtKB/TrEMBL
Pfam CENP-W UniProtKB/TrEMBL
UniProt A0A8C0L738 ENTREZGENE
  A0A8C0MT46 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0Q256 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RQR0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:39114 ENTREZGENE