MYO1E (myosin IE) - Rat Genome Database

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Gene: MYO1E (myosin IE) Canis lupus familiaris
Analyze
Symbol: MYO1E
Name: myosin IE
RGD ID: 12119525
Description: ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN hemopoiesis (ortholog); in utero embryonic development (ortholog); kidney development (ortholog); ASSOCIATED WITH benign familial hematuria (ortholog); Bloom syndrome (ortholog); colorectal cancer (ortholog); FOUND IN cuticular plate (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: myosin-Ie; unconventional myosin-Ie
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13024,067,622 - 24,265,567 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3024,068,283 - 24,265,311 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3024,041,333 - 24,239,771 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03024,236,065 - 24,434,141 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3024,236,074 - 24,433,904 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13024,161,240 - 24,360,201 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03024,244,241 - 24,442,581 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03024,387,998 - 24,586,599 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202   PMID:37756605  


Genomics

Comparative Map Data
MYO1E
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13024,067,622 - 24,265,567 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3024,068,283 - 24,265,311 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3024,041,333 - 24,239,771 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03024,236,065 - 24,434,141 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3024,236,074 - 24,433,904 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13024,161,240 - 24,360,201 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03024,244,241 - 24,442,581 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03024,387,998 - 24,586,599 (-)NCBIUU_Cfam_GSD_1.0
MYO1E
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381559,132,434 - 59,372,871 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1559,132,434 - 59,372,871 (-)EnsemblGRCh38hg38GRCh38
GRCh371559,424,633 - 59,665,070 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361557,215,855 - 57,452,363 (-)NCBINCBI36Build 36hg18NCBI36
Build 341557,215,855 - 57,452,363NCBI
Celera1536,316,513 - 36,553,029 (-)NCBICelera
Cytogenetic Map15q22.2NCBI
HuRef1536,250,377 - 36,487,296 (-)NCBIHuRef
CHM1_11559,546,143 - 59,783,017 (-)NCBICHM1_1
T2T-CHM13v2.01556,934,526 - 57,174,966 (-)NCBIT2T-CHM13v2.0
Myo1e
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39970,114,632 - 70,307,349 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl970,114,632 - 70,307,048 (+)EnsemblGRCm39 Ensembl
GRCm38970,207,350 - 70,400,067 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl970,207,350 - 70,399,766 (+)EnsemblGRCm38mm10GRCm38
MGSCv37970,055,157 - 70,247,874 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36970,006,514 - 70,199,231 (+)NCBIMGSCv36mm8
Celera967,429,438 - 67,616,081 (+)NCBICelera
Cytogenetic Map9DNCBI
cM Map939.41NCBI
Myo1e
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8879,768,828 - 79,961,048 (+)NCBIGRCr8
mRatBN7.2870,887,934 - 71,080,180 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl870,887,870 - 71,080,169 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx876,421,230 - 76,614,265 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0874,694,252 - 74,887,286 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0872,532,530 - 72,725,108 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0876,644,715 - 76,840,240 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl876,754,492 - 76,839,593 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0876,241,676 - 76,432,611 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4874,680,727 - 74,884,376 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1874,699,780 - 74,903,430 (+)NCBI
Celera870,648,832 - 70,842,630 (-)NCBICelera
Cytogenetic Map8q24NCBI
Myo1e
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545015,456,580 - 15,551,584 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545015,421,843 - 15,551,680 (+)NCBIChiLan1.0ChiLan1.0
MYO1E
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21648,401,647 - 48,638,895 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11552,584,087 - 52,820,740 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01538,106,599 - 38,343,040 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11556,413,570 - 56,649,683 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1556,413,570 - 56,649,722 (-)Ensemblpanpan1.1panPan2
Myo1e
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640102,396,361 - 102,587,555 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647120,244,397 - 20,435,648 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647120,244,424 - 20,435,604 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYO1E
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1112,677,821 - 112,901,993 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11112,677,545 - 112,902,005 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21124,676,396 - 124,901,516 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MYO1E
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12624,138,462 - 24,378,602 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2624,138,829 - 24,379,143 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048116,944,885 - 117,186,889 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myo1e
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478112,682,514 - 12,871,099 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478112,682,614 - 12,866,990 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MYO1E
2317 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 6 5 6 10 6
Low 5 16 6 1 6 6 12
Below cutoff 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000026368   ⟹   ENSCAFP00000024489
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3024,068,283 - 24,265,311 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000068956   ⟹   ENSCAFP00000053808
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3024,083,547 - 24,265,311 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000069552   ⟹   ENSCAFP00000053972
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3024,068,283 - 24,265,311 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845028881   ⟹   ENSCAFP00845022723
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3024,236,074 - 24,433,904 (-)Ensembl
RefSeq Acc Id: XM_038442482   ⟹   XP_038298410
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03024,236,065 - 24,434,141 (-)NCBI
RefSeq Acc Id: XM_038516942   ⟹   XP_038372870
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13024,161,240 - 24,360,201 (-)NCBI
RefSeq Acc Id: XM_038580563   ⟹   XP_038436491
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03024,387,998 - 24,586,599 (-)NCBI
RefSeq Acc Id: XM_038644875   ⟹   XP_038500803
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03024,244,241 - 24,442,581 (-)NCBI
RefSeq Acc Id: XM_535500   ⟹   XP_535500
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13024,067,622 - 24,265,567 (-)NCBI
Dog10K_Boxer_Tasha3024,041,333 - 24,239,771 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_535500   ⟸   XM_535500
- UniProtKB: A0A8C0KDL4 (UniProtKB/TrEMBL),   A0A8C0N2D5 (UniProtKB/TrEMBL),   A0A8I3NQ19 (UniProtKB/TrEMBL),   A0A8C0Z7K3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000053808   ⟸   ENSCAFT00000068956
RefSeq Acc Id: ENSCAFP00000053972   ⟸   ENSCAFT00000069552
RefSeq Acc Id: ENSCAFP00000024489   ⟸   ENSCAFT00000026368
RefSeq Acc Id: XP_038372870   ⟸   XM_038516942
RefSeq Acc Id: XP_038500803   ⟸   XM_038644875
RefSeq Acc Id: XP_038298410   ⟸   XM_038442482
- UniProtKB: A0A8C0KDL4 (UniProtKB/TrEMBL),   A0A8C0N2D5 (UniProtKB/TrEMBL),   A0A8I3NQ19 (UniProtKB/TrEMBL),   A0A8C0Z7K3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038436491   ⟸   XM_038580563
- UniProtKB: A0A8C0KDL4 (UniProtKB/TrEMBL),   A0A8C0N2D5 (UniProtKB/TrEMBL),   A0A8C0Z7K3 (UniProtKB/TrEMBL),   A0A8I3NQ19 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845022723   ⟸   ENSCAFT00845028881
Protein Domains
Myosin motor   SH3   TH1

Promoters
RGD ID:13688540
Promoter ID:EPDNEW_C6609
Type:initiation region
Name:MYO1E_1
Description:myosin IE
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13024,265,669 - 24,265,729EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000016635 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030010075 UniProtKB/TrEMBL
  ENSCAFG00040025978 UniProtKB/TrEMBL
  ENSCAFG00845016229 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000026368.5 UniProtKB/TrEMBL
  ENSCAFT00030018890.1 UniProtKB/TrEMBL
  ENSCAFT00040048613.1 UniProtKB/TrEMBL
  ENSCAFT00040048619.1 UniProtKB/TrEMBL
  ENSCAFT00845028881 ENTREZGENE
  ENSCAFT00845028881.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.820 UniProtKB/TrEMBL
  1.20.5.4820 UniProtKB/TrEMBL
  1.20.58.530 UniProtKB/TrEMBL
  3.40.850.10 UniProtKB/TrEMBL
  Myosin VI head, motor domain, U50 subdomain UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro Ie/If_SH3 UniProtKB/TrEMBL
  IQ_motif_EF-hand-BS UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/TrEMBL
  Myosin_head_motor_dom UniProtKB/TrEMBL
  Myosin_TH1 UniProtKB/TrEMBL
  MYSc_Myo1 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
KEGG Report cfa:478325 UniProtKB/TrEMBL
NCBI Gene MYO1E ENTREZGENE
PANTHER MYOSIN UniProtKB/TrEMBL
  UNCONVENTIONAL MYOSIN-IE UniProtKB/TrEMBL
Pfam Myosin_head UniProtKB/TrEMBL
  Myosin_TH1 UniProtKB/TrEMBL
  SH3_1 UniProtKB/TrEMBL
PRINTS MYOSINHEAVY UniProtKB/TrEMBL
  SH3DOMAIN UniProtKB/TrEMBL
PROSITE MYOSIN_MOTOR UniProtKB/TrEMBL
  PS50096 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  TH1 UniProtKB/TrEMBL
SMART MYSc UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A8C0KDL4 ENTREZGENE
  A0A8C0N2D5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0Z7K3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NQ19 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:43564 ENTREZGENE