SPINK13 (serine peptidase inhibitor Kazal type 13)

Gene: SPINK13 (serine peptidase inhibitor Kazal type 13) Canis lupus familiaris

Analyze

Symbol:

SPINK13

Name:

serine peptidase inhibitor Kazal type 13

RGD ID:

12110492

Description:

INVOLVED IN negative regulation of acrosome reaction (ortholog); ASSOCIATED WITH familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); Hereditary Neoplastic Syndromes (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC111095604; serine peptidase inhibitor, Kazal type 13 (putative); serine protease inhibitor Kazal-type 13; uncharacterized LOC111095604

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	60,480,662 - 60,491,529 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	60,245,241 - 60,299,509 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	60,969,701 - 61,024,015 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	4	60,749,838 - 60,804,082 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	60,876,598 - 60,930,892 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	61,394,686 - 61,448,931 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

familial adenomatous polyposis 1 (ISO)

genetic disease (ISO)

Hereditary Neoplastic Syndromes (ISO)

Neurodevelopmental Disorders (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of acrosome reaction (ISO)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

SPINK13
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	60,480,662 - 60,491,529 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	60,245,241 - 60,299,509 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	60,969,701 - 61,024,015 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	4	60,749,838 - 60,804,082 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	60,876,598 - 60,930,892 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	61,394,686 - 61,448,931 (-)	NCBI		UU_Cfam_GSD_1.0

SPINK13
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	148,268,794 - 148,286,255 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	148,268,180 - 148,286,255 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	147,648,357 - 147,665,818 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	147,628,616 - 147,645,966 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	5	143,727,787 - 143,745,137 (+)	NCBI		Celera
Cytogenetic Map	5	q32	NCBI
HuRef	5	142,795,553 - 142,812,903 (+)	NCBI		HuRef
CHM1_1	5	147,081,121 - 147,098,471 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	148,803,308 - 148,820,769 (+)	NCBI		T2T-CHM13v2.0

Spink13
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	62,740,570 - 62,874,458 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	62,740,606 - 62,874,458 (-)	Ensembl		GRCm39 Ensembl
GRCm38	18	62,607,499 - 62,741,387 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	62,607,535 - 62,741,387 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	62,767,194 - 62,901,041 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
Celera	18	63,883,548 - 64,015,282 (-)	NCBI		Celera
Cytogenetic Map	18	E1	NCBI
cM Map	18	35.37	NCBI

Spink13
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	58,335,146 - 58,476,569 (-)	NCBI		GRCr8
mRatBN7.2	18	56,064,839 - 56,206,257 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	56,064,839 - 56,206,257 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	58,150,799 - 58,288,413 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	58,872,932 - 59,014,451 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	56,688,673 - 56,830,096 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	57,935,271 - 58,081,096 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	57,935,271 - 58,081,096 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	57,161,386 - 57,182,561 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	18	57,305,926 - 57,306,089 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	58,625,245 - 58,848,729 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	18	54,210,046 - 54,354,091 (-)	NCBI		Celera
Cytogenetic Map	18	q12.1	NCBI

SPINK13
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	143,496,870 - 143,517,215 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	141,640,097 - 141,656,558 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	143,692,686 - 143,713,035 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	149,702,870 - 149,721,406 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	149,702,870 - 149,721,406 (+)	Ensembl	panpan1.1		panPan2

SPINK13
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	2	149,576,340 - 149,586,186 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SPINK13
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	50,906,457 - 50,925,757 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	50,908,942 - 50,925,546 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	26,830,150 - 26,848,843 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in SPINK13
127 total Variants

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_022417835	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038474009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038535106	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038599401	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038663711	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000051	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000088	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000355	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_022417835 ⟹ XP_022273543

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	4	60,480,662 - 60,491,529 (-)	NCBI
Dog10K_Boxer_Tasha	4	60,245,241 - 60,299,509 (-)	NCBI

Sequence:

show sequence

GGTTCTCTCATGTTTGGAAAGTCAGCTGTGCAAGATATTAGGAATAAACTATCTCAAGCCTTTT
CCTAGGCCTCACCTGAGCAGGACATTGGATGAGATCAAATGGCTTCCTTTTCCTACATGATCAT
ATTTTTCCTGGTTTCCTCCACTTTGGCACATACTGTTTCTTCAGAAATCTTCAAGCCACATGCT
ATAAATAAATGGCCTAAGCCTCCATGTAAAATGTACTACTCAGTGGATCCTTCTTATACATCAC
AATGTCCAGATGTGATATCATATGTTTGTGCTACAAATGGTCACACTTACCAGAATGAGTGTTT
TTTTTGTGTTGATCAGTGGGAATTTGGTCTTCATATTAAATTTTATAAATATGGAAAATGTGGA
TAATGAGTTAACAGAGTACTACACTTGTTTATTCATTTTCACTACATAATGCTGAAAATTATTT
CTTTGGAATTTGAGGGCGTATGATAAATAACACATCTATGTTACACCCAAATTTGGAAAAAAAA
AACCTGAAAACAAATGGAGAATCAACTGACATATTTATTACAAATAAACATAATAATGAAAGAA
GTGGTATTTACTCCTGTGTAGTGGTGTTTAAGTTAAGCTTTCATTTTGTTTGCGTCTAACATCT
GTCATCAAATGGTATTACACTCCCCAAATTAAACTTACCCCAAAGTGCAGGCTCCCTGCACTGT
GAGATCCGACCCTGCCCCACTAGTCTCACCCGAAGACATGAGCATAAGAGAAAACATCTCACAG
GCACATACAAAGAGCTTTTTGAGAATTTTTGCCTCATACTCATAAATGAAGTTCACCTTCATTA
AAGGAAAACAAATGGGGACGCCTGGTGGCTCAGTGGTTGAGCACC

hide sequence

RefSeq Acc Id:

XM_038474009 ⟹ XP_038329937

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	4	60,749,838 - 60,804,082 (-)	NCBI

RefSeq Acc Id:

XM_038535106 ⟹ XP_038391034

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	4	61,394,686 - 61,448,931 (-)	NCBI

RefSeq Acc Id:

XM_038599401 ⟹ XP_038455329

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	4	60,876,598 - 60,930,892 (-)	NCBI

RefSeq Acc Id:

XM_038663711 ⟹ XP_038519639

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	4	60,969,701 - 61,024,015 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_022273543	(Get FASTA)	NCBI Sequence Viewer
	XP_038329937	(Get FASTA)	NCBI Sequence Viewer
	XP_038391034	(Get FASTA)	NCBI Sequence Viewer
	XP_038455329	(Get FASTA)	NCBI Sequence Viewer
	XP_038519639	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_022273543 ⟸ XM_022417835
- Sequence:	show sequence MASFSYMIIFFLVSSTLAHTVSSEIFKPHAINKWPKPPCKMYYSVDPSYTSQCPDVISYVCATN GHTYQNECFFCVDQWEFGLHIKFYKYGKCG hide sequence

RefSeq Acc Id:

XP_038329937 ⟸ XM_038474009

RefSeq Acc Id:

XP_038455329 ⟸ XM_038599401

RefSeq Acc Id:

XP_038519639 ⟸ XM_038663711

RefSeq Acc Id:

XP_038391034 ⟸ XM_038535106

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	SPINK13	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-01-14	SPINK13	serine peptidase inhibitor Kazal type 13	LOC111095604	uncharacterized LOC111095604	Data merged from RGD:13260105	737654	PROVISIONAL
2019-10-08	SPINK13	serine peptidase inhibitor Kazal type 13	SPINK13	serine peptidase inhibitor, Kazal type 13 (putative)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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