LIPN (lipase family member N) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: LIPN (lipase family member N) Canis lupus familiaris
Analyze
Symbol: LIPN
Name: lipase family member N
RGD ID: 12106899
Description: ENCODES a protein that exhibits hydrolase activity (inferred); hydrolase activity, acting on ester bonds (inferred); INVOLVED IN lipid catabolic process (inferred); lipid metabolic process (inferred); ASSOCIATED WITH autoimmune lymphoproliferative syndrome (ortholog); autosomal recessive congenital ichthyosis 8 (ortholog); genetic disease (ortholog); FOUND IN intracellular membrane-bounded organelle (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: lipase member N
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12638,573,408 - 38,588,171 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2638,389,877 - 38,404,593 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02640,157,832 - 40,172,516 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2640,157,878 - 40,172,515 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12637,996,879 - 38,011,552 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02637,593,517 - 37,608,223 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02638,862,983 - 38,877,692 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
LIPN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12638,573,408 - 38,588,171 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2638,389,877 - 38,404,593 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02640,157,832 - 40,172,516 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2640,157,878 - 40,172,515 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12637,996,879 - 38,011,552 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02637,593,517 - 37,608,223 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02638,862,983 - 38,877,692 (+)NCBIUU_Cfam_GSD_1.0
LIPN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381088,757,226 - 88,779,626 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1088,759,982 - 88,779,626 (+)EnsemblGRCh38hg38GRCh38
GRCh371090,519,777 - 90,539,383 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361090,511,143 - 90,527,979 (+)NCBINCBI36Build 36hg18NCBI36
Celera1084,268,049 - 84,284,832 (+)NCBICelera
Cytogenetic Map10q23.31NCBI
HuRef1084,155,904 - 84,172,685 (+)NCBIHuRef
CHM1_11090,803,232 - 90,820,059 (+)NCBICHM1_1
T2T-CHM13v2.01089,641,224 - 89,663,572 (+)NCBIT2T-CHM13v2.0
Lipn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391934,044,458 - 34,063,346 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1934,044,758 - 34,062,318 (+)EnsemblGRCm39 Ensembl
GRCm381934,067,058 - 34,085,946 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1934,067,358 - 34,084,918 (+)EnsemblGRCm38mm10GRCm38
MGSCv371934,141,848 - 34,159,408 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361934,133,355 - 34,150,915 (+)NCBIMGSCv36mm8
Celera1934,844,100 - 34,861,644 (+)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1929.32NCBI
Lipn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81240,998,154 - 241,016,658 (+)NCBIGRCr8
mRatBN7.21231,584,950 - 231,603,456 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1231,584,956 - 231,603,468 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1239,976,758 - 239,992,921 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01246,898,829 - 246,914,996 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01239,736,903 - 239,753,074 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01252,375,941 - 252,394,226 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1252,375,933 - 252,396,460 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01259,600,620 - 259,616,791 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41237,932,634 - 237,948,805 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1228,700,030 - 228,716,201 (+)NCBICelera
Cytogenetic Map1q52NCBI
Lipn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554254,187,537 - 4,205,066 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554254,187,537 - 4,205,066 (-)NCBIChiLan1.0ChiLan1.0
LIPN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28100,779,271 - 100,798,806 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110100,784,585 - 100,804,121 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01085,485,727 - 85,505,268 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11088,990,571 - 89,007,327 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1088,990,571 - 89,007,327 (+)Ensemblpanpan1.1panPan2
Lipn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721378,328,481 - 78,361,805 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936735445,985 - 464,340 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936735445,985 - 464,340 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100156277
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14100,691,955 - 100,710,316 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114100,678,863 - 100,710,229 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214109,671,333 - 109,695,023 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LIPN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1982,182,344 - 82,201,550 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl982,185,101 - 82,201,549 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604842,863,858 - 42,881,650 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lipn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479115,055,126 - 15,065,876 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479115,050,707 - 15,066,223 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LIPN
711 total Variants

Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005636667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038437699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038437700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038459436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038459437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038512576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038512577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038576064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038576065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038640280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038640281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00845052503   ⟹   ENSCAFP00845041193
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2640,157,878 - 40,172,515 (+)Ensembl
RefSeq Acc Id: XM_038437699   ⟹   XP_038293627
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02640,157,832 - 40,172,516 (+)NCBI
RefSeq Acc Id: XM_038437700   ⟹   XP_038293628
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02640,157,832 - 40,172,516 (+)NCBI
RefSeq Acc Id: XM_038459436   ⟹   XP_038315364
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2638,389,877 - 38,404,593 (+)NCBI
RefSeq Acc Id: XM_038459437   ⟹   XP_038315365
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2638,389,877 - 38,404,593 (+)NCBI
RefSeq Acc Id: XM_038512576   ⟹   XP_038368504
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12637,996,880 - 38,011,552 (+)NCBI
RefSeq Acc Id: XM_038512577   ⟹   XP_038368505
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12637,996,879 - 38,011,552 (+)NCBI
RefSeq Acc Id: XM_038576064   ⟹   XP_038431992
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02638,862,983 - 38,877,692 (+)NCBI
RefSeq Acc Id: XM_038576065   ⟹   XP_038431993
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02638,862,983 - 38,877,692 (+)NCBI
RefSeq Acc Id: XM_038640280   ⟹   XP_038496208
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02637,593,518 - 37,608,223 (+)NCBI
RefSeq Acc Id: XM_038640281   ⟹   XP_038496209
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02637,593,517 - 37,608,223 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_038368505   ⟸   XM_038512577
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038368504   ⟸   XM_038512576
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038496209   ⟸   XM_038640281
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038496208   ⟸   XM_038640280
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038293627   ⟸   XM_038437699
- Peptide Label: isoform X1
- UniProtKB: A0A8I3QKA9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038293628   ⟸   XM_038437700
- Peptide Label: isoform X2
- UniProtKB: A0A8I3QKA9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038315364   ⟸   XM_038459436
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PCI1 (UniProtKB/TrEMBL),   A0A8P0TBN0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038315365   ⟸   XM_038459437
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PCI1 (UniProtKB/TrEMBL),   A0A8P0TBN0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038431992   ⟸   XM_038576064
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PCI1 (UniProtKB/TrEMBL),   A0A8P0TBN0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038431993   ⟸   XM_038576065
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PCI1 (UniProtKB/TrEMBL),   A0A8P0TBN0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845041193   ⟸   ENSCAFT00845052503
Protein Domains
Partial AB-hydrolase lipase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000055887 UniProtKB/TrEMBL
  ENSCAFG00030020643 UniProtKB/TrEMBL
  ENSCAFG00040024124 UniProtKB/TrEMBL
  ENSCAFG00845029649 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000089458.2 UniProtKB/TrEMBL
  ENSCAFT00030037876.1 UniProtKB/TrEMBL
  ENSCAFT00040044954.1 UniProtKB/TrEMBL
  ENSCAFT00845052503 ENTREZGENE
  ENSCAFT00845052503.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  AB_hydrolase_lipase UniProtKB/TrEMBL
  Lipase_euk UniProtKB/TrEMBL
NCBI Gene LIPN ENTREZGENE
PANTHER LIPASE MEMBER N UniProtKB/TrEMBL
  LYSOSOMAL ACID LIPASE-RELATED UniProtKB/TrEMBL
Pfam Abhydro_lipase UniProtKB/TrEMBL
PIRSF Steryl_ester_lip UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A8C0PCI1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3QKA9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0TBN0 ENTREZGENE
UniProt Secondary A0A8P0TBN0 UniProtKB/TrEMBL