STKLD1 (serine/threonine kinase like domain containing 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: STKLD1 (serine/threonine kinase like domain containing 1) Canis lupus familiaris
Analyze
Symbol: STKLD1
Name: serine/threonine kinase like domain containing 1
RGD ID: 12105986
Description: ENCODES a protein that exhibits ATP binding (inferred); protein kinase activity (inferred); protein serine/threonine kinase activity (inferred); ASSOCIATED WITH developmental and epileptic encephalopathy 14 (ortholog); Ehlers-Danlos syndrome classic type 1 (ortholog); genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: C9H9orf96; serine/threonine kinase-like domain-containing protein STKLD1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1949,807,272 - 49,827,611 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl949,807,250 - 49,827,567 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha949,088,729 - 49,108,851 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0950,681,212 - 50,701,368 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl950,679,931 - 50,701,324 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1949,443,623 - 49,463,762 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0949,785,100 - 49,805,262 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0949,863,140 - 49,883,340 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
STKLD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1949,807,272 - 49,827,611 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl949,807,250 - 49,827,567 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha949,088,729 - 49,108,851 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0950,681,212 - 50,701,368 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl950,679,931 - 50,701,324 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1949,443,623 - 49,463,762 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0949,785,100 - 49,805,262 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0949,863,140 - 49,883,340 (+)NCBIUU_Cfam_GSD_1.0
STKLD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389133,376,366 - 133,406,096 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9133,376,366 - 133,406,096 (+)EnsemblGRCh38hg38GRCh38
GRCh379136,243,237 - 136,271,220 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369135,233,105 - 135,261,041 (+)NCBINCBI36Build 36hg18NCBI36
Build 349133,272,837 - 133,300,773NCBI
Celera9106,793,768 - 106,821,789 (+)NCBICelera
Cytogenetic Map9q34.2NCBI
HuRef9105,743,194 - 105,773,047 (+)NCBIHuRef
CHM1_19136,393,410 - 136,421,727 (+)NCBICHM1_1
T2T-CHM13v2.09145,590,326 - 145,620,528 (+)NCBIT2T-CHM13v2.0
Stkld1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39226,823,533 - 26,843,508 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl226,824,059 - 26,843,508 (+)EnsemblGRCm39 Ensembl
GRCm38226,933,521 - 26,953,496 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl226,934,047 - 26,953,496 (+)EnsemblGRCm38mm10GRCm38
MGSCv37226,789,589 - 26,809,016 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36226,756,078 - 26,775,505 (+)NCBIMGSCv36mm8
Celera226,643,814 - 26,663,241 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map219.12NCBI
Stkld1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8330,659,659 - 30,678,650 (+)NCBIGRCr8
mRatBN7.2310,261,583 - 10,280,850 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl310,261,828 - 10,280,566 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx313,321,826 - 13,340,565 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0321,907,227 - 21,925,966 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0320,162,528 - 20,181,267 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.035,481,524 - 5,500,568 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl35,481,522 - 5,500,583 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0310,843,542 - 10,863,228 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.435,830,687 - 5,849,484 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.135,836,030 - 5,850,402 (+)NCBI
Celera35,059,877 - 5,078,674 (+)NCBICelera
Cytogenetic Map3p13NCBI
Stkld1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555132,726,339 - 2,744,998 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555132,726,339 - 2,745,099 (+)NCBIChiLan1.0ChiLan1.0
STKLD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2115,947,714 - 5,977,020 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan195,950,050 - 5,979,360 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09104,499,706 - 104,528,872 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19133,111,802 - 133,140,430 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9133,111,802 - 133,140,430 (+)Ensemblpanpan1.1panPan2
Stkld1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947199,863,554 - 199,882,555 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366693,492,615 - 3,509,583 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366693,492,507 - 3,511,297 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STKLD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1272,995,842 - 273,011,443 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11272,988,767 - 273,012,007 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
STKLD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1124,732,267 - 4,763,687 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl124,732,772 - 4,759,244 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666058229,313 - 257,244 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stkld1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247601,835,478 - 1,850,864 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247601,833,797 - 1,851,379 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in STKLD1
291 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 8
Low 4 7 1 1
Below cutoff 5 5 18 6 6 6 6 6 5 9 5

Sequence


RefSeq Acc Id: ENSCAFT00000031425   ⟹   ENSCAFP00000029252
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl949,807,250 - 49,827,567 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000083960   ⟹   ENSCAFP00000063725
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl949,807,250 - 49,827,567 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845017822   ⟹   ENSCAFP00845013880
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl950,679,931 - 50,701,324 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845017948   ⟹   ENSCAFP00845013982
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl950,679,931 - 50,701,324 (+)Ensembl
RefSeq Acc Id: XM_022423634   ⟹   XP_022279342
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1949,807,272 - 49,827,611 (+)NCBI
Dog10K_Boxer_Tasha949,088,729 - 49,108,851 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038486985   ⟹   XP_038342913
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1949,443,623 - 49,463,762 (+)NCBI
RefSeq Acc Id: XM_038548833   ⟹   XP_038404761
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0949,863,140 - 49,883,340 (+)NCBI
RefSeq Acc Id: XM_038612782   ⟹   XP_038468710
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0949,785,100 - 49,805,262 (+)NCBI
RefSeq Acc Id: XM_038678078   ⟹   XP_038534006
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0950,681,212 - 50,701,368 (+)NCBI
RefSeq Acc Id: XP_022279342   ⟸   XM_022423634
- UniProtKB: A0A8C0QT73 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000029252   ⟸   ENSCAFT00000031425
RefSeq Acc Id: ENSCAFP00000063725   ⟸   ENSCAFT00000083960
RefSeq Acc Id: XP_038342913   ⟸   XM_038486985
RefSeq Acc Id: XP_038468710   ⟸   XM_038612782
RefSeq Acc Id: XP_038534006   ⟸   XM_038678078
- UniProtKB: A0A8C0QT73 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038404761   ⟸   XM_038548833
- UniProtKB: A0A8C0QT73 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845013982   ⟸   ENSCAFT00845017948
RefSeq Acc Id: ENSCAFP00845013880   ⟸   ENSCAFT00845017822
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000019765 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00845010122 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000031425.4 UniProtKB/TrEMBL
  ENSCAFT00000083960.2 UniProtKB/TrEMBL
  ENSCAFT00845017822 ENTREZGENE
  ENSCAFT00845017822.1 UniProtKB/TrEMBL
  ENSCAFT00845017948.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
NCBI Gene STKLD1 ENTREZGENE
PANTHER SERINE/THREONINE KINASE-LIKE DOMAIN-CONTAINING PROTEIN STKLD1 UniProtKB/TrEMBL
  SERINE/THREONINE PROTEIN KINASE UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A8C0QT73 ENTREZGENE
  A0A8I3NG46_CANLF UniProtKB/TrEMBL
  A0A8I3RXM5_CANLF UniProtKB/TrEMBL
  A0A8P0NKY3_CANLF UniProtKB/TrEMBL
  A0A8P0PCE7_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:46924 ENTREZGENE