ELOVL4 (ELOVL fatty acid elongase 4) - Rat Genome Database

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Gene: ELOVL4 (ELOVL fatty acid elongase 4) Canis lupus familiaris
Analyze
Symbol: ELOVL4
Name: ELOVL fatty acid elongase 4
RGD ID: 12104806
Description: ENCODES a protein that exhibits fatty acid elongase activity (inferred); transferase activity (inferred); very-long-chain 3-ketoacyl-CoA synthase activity (inferred); INVOLVED IN cellular biosynthetic process (inferred); cellular lipid metabolic process (inferred); fatty acid biosynthetic process (inferred); PARTICIPATES IN alpha-linolenic acid metabolic pathway; linoleic acid metabolic pathway; ASSOCIATED WITH corneal dystrophy (ortholog); fundus dystrophy (ortholog); Ichthyosis, Spastic Quadriplegia, and Mental Retardation (ortholog); FOUND IN integral component of endoplasmic reticulum membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4; elongation of very long chain fatty acids protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11240,845,357 - 40,876,658 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1240,846,202 - 40,876,758 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1240,717,528 - 40,748,986 (-)NCBI
ROS_Cfam_1.01241,608,796 - 41,640,301 (-)NCBI
ROS_Cfam_1.0 Ensembl1241,608,796 - 41,640,369 (-)Ensembl
UMICH_Zoey_3.11240,922,521 - 40,953,970 (-)NCBI
UNSW_CanFamBas_1.01240,898,942 - 40,930,398 (-)NCBI
UU_Cfam_GSD_1.01241,049,872 - 41,081,359 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
ELOVL4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11240,845,357 - 40,876,658 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1240,846,202 - 40,876,758 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1240,717,528 - 40,748,986 (-)NCBI
ROS_Cfam_1.01241,608,796 - 41,640,301 (-)NCBI
ROS_Cfam_1.0 Ensembl1241,608,796 - 41,640,369 (-)Ensembl
UMICH_Zoey_3.11240,922,521 - 40,953,970 (-)NCBI
UNSW_CanFamBas_1.01240,898,942 - 40,930,398 (-)NCBI
UU_Cfam_GSD_1.01241,049,872 - 41,081,359 (-)NCBI
ELOVL4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38679,914,814 - 79,947,553 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl679,914,814 - 79,947,553 (-)EnsemblGRCh38hg38GRCh38
GRCh37680,624,531 - 80,657,270 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36680,681,248 - 80,713,941 (-)NCBINCBI36hg18NCBI36
Build 34680,681,248 - 80,713,941NCBI
Celera681,042,504 - 81,075,295 (-)NCBI
Cytogenetic Map6q14.1NCBI
HuRef677,847,380 - 77,880,171 (-)NCBIHuRef
CHM1_1680,722,020 - 80,754,791 (-)NCBICHM1_1
T2T-CHM13v2.0681,123,209 - 81,155,949 (-)NCBI
Elovl4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39983,660,745 - 83,688,358 (-)NCBIGRCm39mm39
GRCm39 Ensembl983,660,745 - 83,688,330 (-)Ensembl
GRCm38983,778,692 - 83,806,305 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl983,778,692 - 83,806,277 (-)EnsemblGRCm38mm10GRCm38
MGSCv37983,672,299 - 83,699,912 (-)NCBIGRCm37mm9NCBIm37
MGSCv36983,575,410 - 83,602,818 (-)NCBImm8
Celera980,877,487 - 80,906,281 (-)NCBICelera
Cytogenetic Map9E2NCBI
Elovl4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2884,702,916 - 84,729,466 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl884,702,362 - 84,729,697 (-)Ensembl
Rnor_6.0891,310,690 - 91,338,625 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl891,310,630 - 91,338,843 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0890,830,571 - 90,857,120 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4888,855,155 - 88,881,703 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1888,873,228 - 88,901,172 (-)NCBI
Celera884,351,953 - 84,378,505 (-)NCBICelera
Cytogenetic Map8q31NCBI
Elovl4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555027,764,359 - 7,774,572 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555027,764,451 - 7,774,503 (-)NCBIChiLan1.0ChiLan1.0
ELOVL4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1681,068,876 - 81,101,644 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl681,068,882 - 81,102,050 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0677,798,058 - 77,830,840 (-)NCBIMhudiblu_PPA_v0panPan3
Elovl4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494676,194,846 - 76,224,005 (-)NCBI
SpeTri2.0NW_00493651010,246,901 - 10,276,049 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELOVL4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl186,163,868 - 86,195,987 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1186,163,845 - 86,196,036 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2196,867,779 - 96,896,868 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ELOVL4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1134,652,674 - 4,687,308 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl134,652,677 - 4,687,294 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666040180,883,243 - 180,916,132 (-)NCBIVero_WHO_p1.0
Elovl4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248196,572,161 - 6,602,072 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248196,572,263 - 6,601,991 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 8 6 12 8
Low 2 8 1 6 2
Below cutoff 3 5 4 4 5 4 5 4 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000047184   ⟹   ENSCAFP00000043098
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1240,846,202 - 40,876,758 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845016255   ⟹   ENSCAFP00845012645
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1241,608,796 - 41,640,369 (-)Ensembl
RefSeq Acc Id: XM_022426279   ⟹   XP_022281987
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11240,845,357 - 40,876,170 (-)NCBI
Dog10K_Boxer_Tasha1240,717,528 - 40,748,371 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038492304   ⟹   XP_038348232
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11240,922,521 - 40,953,970 (-)NCBI
RefSeq Acc Id: XM_038492305   ⟹   XP_038348233
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11240,922,521 - 40,953,341 (-)NCBI
RefSeq Acc Id: XM_038554597   ⟹   XP_038410525
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01241,049,872 - 41,081,359 (-)NCBI
RefSeq Acc Id: XM_038554598   ⟹   XP_038410526
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01241,049,872 - 41,080,726 (-)NCBI
RefSeq Acc Id: XM_038618454   ⟹   XP_038474382
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01240,898,942 - 40,930,398 (-)NCBI
RefSeq Acc Id: XM_038618455   ⟹   XP_038474383
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01240,898,942 - 40,929,759 (-)NCBI
RefSeq Acc Id: XM_038684018   ⟹   XP_038539946
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01241,608,796 - 41,640,301 (-)NCBI
RefSeq Acc Id: XM_038684019   ⟹   XP_038539947
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01241,608,796 - 41,639,670 (-)NCBI
RefSeq Acc Id: XM_539015   ⟹   XP_539015
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11240,845,357 - 40,876,658 (-)NCBI
Dog10K_Boxer_Tasha1240,717,528 - 40,748,986 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_539015   ⟸   XM_539015
- Peptide Label: isoform X1
- UniProtKB: J9PBB9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022281987   ⟸   XM_022426279
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCAFP00000043098   ⟸   ENSCAFT00000047184
RefSeq Acc Id: XP_038348232   ⟸   XM_038492304
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038348233   ⟸   XM_038492305
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038474382   ⟸   XM_038618454
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038474383   ⟸   XM_038618455
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038539946   ⟸   XM_038684018
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038539947   ⟸   XM_038684019
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038410525   ⟸   XM_038554597
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038410526   ⟸   XM_038554598
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCAFP00845012645   ⟸   ENSCAFT00845016255


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000030132 Ensembl
  ENSCAFG00845009234 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00845012645 ENTREZGENE
  ENSCAFP00845012645.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00845016255 ENTREZGENE
  ENSCAFT00845016255.1 UniProtKB/TrEMBL
InterPro ELO_CS UniProtKB/TrEMBL
  ELO_fam UniProtKB/TrEMBL
  ELOVL4 UniProtKB/TrEMBL
NCBI Gene ELOVL4 ENTREZGENE
PANTHER PTHR11157 UniProtKB/TrEMBL
Pfam ELO UniProtKB/TrEMBL
PROSITE ELO UniProtKB/TrEMBL
UniProt A0A8I3NBA5_CANLF UniProtKB/TrEMBL
  J9PBB9 ENTREZGENE
VGNC ID VGNC:40322 ENTREZGENE