DNLZ (DNL-type zinc finger) - Rat Genome Database

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Gene: DNLZ (DNL-type zinc finger) Canis lupus familiaris
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Symbol: DNLZ
Name: DNL-type zinc finger
RGD ID: 12104170
Description: ENCODES a protein that exhibits metal ion binding (inferred); protein-folding chaperone binding (inferred); zinc ion binding (inferred); INVOLVED IN protein folding (inferred); protein import into mitochondrial matrix (inferred); protein stabilization (inferred); ASSOCIATED WITH Adams-Oliver Syndrome 5 (ortholog); autosomal dominant intellectual developmental disorder 8 (ortholog); autosomal dominant nocturnal frontal lobe epilepsy 5 (ortholog); FOUND IN mitochondrion (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DNL-type zinc finger protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1949,120,802 - 49,122,789 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl949,120,818 - 49,122,804 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha948,371,497 - 48,373,350 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0949,997,572 - 49,999,427 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl949,997,567 - 50,001,581 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1948,778,121 - 48,779,896 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0949,072,294 - 49,074,228 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0949,119,821 - 49,121,756 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DNLZ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1949,120,802 - 49,122,789 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl949,120,818 - 49,122,804 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha948,371,497 - 48,373,350 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0949,997,572 - 49,999,427 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl949,997,567 - 50,001,581 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1948,778,121 - 48,779,896 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0949,072,294 - 49,074,228 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0949,119,821 - 49,121,756 (+)NCBIUU_Cfam_GSD_1.0
DNLZ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389136,359,483 - 136,363,744 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9136,359,480 - 136,363,744 (-)EnsemblGRCh38hg38GRCh38
GRCh379139,253,935 - 139,258,196 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369138,376,173 - 138,378,062 (-)NCBINCBI36Build 36hg18NCBI36
Celera9109,771,288 - 109,773,177 (-)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9108,715,708 - 108,717,619 (-)NCBIHuRef
CHM1_19139,404,548 - 139,406,459 (-)NCBICHM1_1
T2T-CHM13v2.09148,588,818 - 148,593,075 (-)NCBIT2T-CHM13v2.0
Dnlz
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39226,238,130 - 26,242,122 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl226,238,133 - 26,242,122 (-)EnsemblGRCm39 Ensembl
GRCm38226,348,118 - 26,352,110 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl226,348,121 - 26,352,110 (-)EnsemblGRCm38mm10GRCm38
MGSCv37226,203,638 - 26,207,630 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36226,203,643 - 26,207,630 (-)NCBIMGSCv36mm8
Celera226,065,813 - 26,069,805 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map218.87NCBI
Dnlz
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8329,568,041 - 29,569,937 (-)NCBIGRCr8
mRatBN7.239,169,948 - 9,171,727 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl39,169,793 - 9,180,551 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx312,223,325 - 12,225,104 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0320,806,555 - 20,808,334 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0319,061,892 - 19,063,671 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.033,796,480 - 3,798,467 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl33,796,480 - 3,798,239 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.039,157,626 - 9,159,542 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.434,522,915 - 4,524,662 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.134,522,914 - 4,524,733 (-)NCBI
Celera33,989,863 - 3,991,610 (-)NCBICelera
Cytogenetic Map3p13NCBI
Dnlz
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555134,359,421 - 4,361,081 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555134,359,421 - 4,361,081 (+)NCBIChiLan1.0ChiLan1.0
DNLZ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2113,022,675 - 3,024,687 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan193,025,204 - 3,029,437 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09107,432,709 - 107,436,360 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19136,411,832 - 136,416,279 (-)NCBIpanpan1.1PanPan1.1panPan2
Dnlz
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947201,935,149 - 201,936,953 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366691,438,227 - 1,439,814 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366691,438,129 - 1,439,909 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNLZ
(Sus scrofa - pig)
No map positions available.
DNLZ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1121,841,598 - 1,846,006 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl121,841,738 - 1,843,462 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660583,370,130 - 3,374,604 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnlz
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247601,531,439 - 1,533,170 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247601,531,439 - 1,533,176 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DNLZ
23 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 10 8 4 1
Low 5 5 11 6 1 6 6 6 3 4 3
Below cutoff 1 5 1 8 2 2

Sequence


RefSeq Acc Id: ENSCAFT00000031301   ⟹   ENSCAFP00000029131
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl949,120,818 - 49,122,804 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845011019   ⟹   ENSCAFP00845008599
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl949,997,567 - 50,001,581 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845011040   ⟹   ENSCAFP00845008615
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl949,998,100 - 50,001,581 (+)Ensembl
RefSeq Acc Id: XM_038486930   ⟹   XP_038342858
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1948,778,121 - 48,779,896 (+)NCBI
RefSeq Acc Id: XM_038548786   ⟹   XP_038404714
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0949,119,821 - 49,121,756 (+)NCBI
RefSeq Acc Id: XM_038612725   ⟹   XP_038468653
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0949,072,294 - 49,074,228 (+)NCBI
RefSeq Acc Id: XM_038678019   ⟹   XP_038533947
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0949,997,572 - 49,999,427 (+)NCBI
RefSeq Acc Id: XM_844193   ⟹   XP_849286
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1949,120,802 - 49,122,789 (+)NCBI
Dog10K_Boxer_Tasha948,371,497 - 48,373,350 (+)NCBI
Sequence:
RefSeq Acc Id: XP_849286   ⟸   XM_844193
- UniProtKB: A0A8C0M5U3 (UniProtKB/TrEMBL),   A0A8C0QTV1 (UniProtKB/TrEMBL),   A0A8I3MU19 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000029131   ⟸   ENSCAFT00000031301
RefSeq Acc Id: XP_038342858   ⟸   XM_038486930
RefSeq Acc Id: XP_038468653   ⟸   XM_038612725
RefSeq Acc Id: XP_038533947   ⟸   XM_038678019
- UniProtKB: A0A8C0M5U3 (UniProtKB/TrEMBL),   A0A8C0QTV1 (UniProtKB/TrEMBL),   A0A8I3MU19 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038404714   ⟸   XM_038548786
- UniProtKB: A0A8C0M5U3 (UniProtKB/TrEMBL),   A0A8C0QTV1 (UniProtKB/TrEMBL),   A0A8I3MU19 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845008615   ⟸   ENSCAFT00845011040
RefSeq Acc Id: ENSCAFP00845008599   ⟸   ENSCAFT00845011019
Protein Domains
DNL-type

Promoters
RGD ID:13684763
Promoter ID:EPDNEW_C2831
Type:multiple initiation site
Name:DNLZ_1
Description:DNL-type zinc finger
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1949,120,819 - 49,120,879EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000019686 Ensembl
  ENSCAFG00000050798 UniProtKB/TrEMBL
  ENSCAFG00030002319 UniProtKB/TrEMBL
  ENSCAFG00040016919 UniProtKB/TrEMBL
  ENSCAFG00845006222 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000098766.1 UniProtKB/TrEMBL
  ENSCAFT00000107288.1 UniProtKB/TrEMBL
  ENSCAFT00030004267.1 UniProtKB/TrEMBL
  ENSCAFT00040031194.1 UniProtKB/TrEMBL
  ENSCAFT00845011019 ENTREZGENE
  ENSCAFT00845011019.1 UniProtKB/TrEMBL
  ENSCAFT00845011040.1 UniProtKB/TrEMBL
InterPro Mt_import_TIM15 UniProtKB/TrEMBL
  Znf_DNL-typ UniProtKB/TrEMBL
KEGG Report cfa:607502 UniProtKB/TrEMBL
NCBI Gene DNLZ ENTREZGENE
PANTHER DNL-TYPE ZINC FINGER PROTEIN UniProtKB/TrEMBL
  PTHR20922 UniProtKB/TrEMBL
Pfam zf-DNL UniProtKB/TrEMBL
PROSITE ZF_DNL UniProtKB/TrEMBL
UniProt A0A8C0M5U3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0QTV1 ENTREZGENE
  A0A8I3MU19 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RUL1_CANLF UniProtKB/TrEMBL
  A0A8P0PQS1_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:40031 ENTREZGENE