B3GALT4 (beta-1,3-galactosyltransferase 4)

Gene: B3GALT4 (beta-1,3-galactosyltransferase 4) Canis lupus familiaris

Analyze

Symbol:

B3GALT4

Name:

beta-1,3-galactosyltransferase 4

RGD ID:

12098536

Description:

ENCODES a protein that exhibits ganglioside galactosyltransferase activity (inferred); glycosyltransferase activity (inferred); hexosyltransferase activity (inferred); INVOLVED IN ganglioside biosynthetic process (ortholog); ASSOCIATED WITH autosomal dominant intellectual developmental disorder 5 (ortholog); genetic disease (ortholog); proteasome-associated autoinflammatory syndrome 1 (ortholog); FOUND IN Golgi apparatus (inferred); Golgi membrane (inferred); membrane (inferred)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

b3Gal-T4; beta-1,3-GalTase 4; beta3Gal-T4; beta3GalT4; gal-T2; galT4; ganglioside galactosyltransferase; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4; UDP-galactose:beta-N-acetyl-galactosamine-beta-1,3-galactosyltransferase

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	2,719,112 - 2,720,997 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	2,800,237 - 2,801,914 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	3,050,290 - 3,052,173 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	3,050,496 - 3,052,173 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	2,717,968 - 2,719,645 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	2,799,458 - 2,801,135 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	2,874,152 - 2,875,829 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant intellectual developmental disorder 5 (ISO)

genetic disease (ISO)

proteasome-associated autoinflammatory syndrome 1 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ganglioside biosynthetic process (ISO)

lipid metabolic process (IEA)

protein glycosylation (IEA)

protein O-linked glycosylation (IBA)

Cellular Component

Golgi apparatus (IEA)

Golgi membrane (IBA,IEA)

membrane (IEA)

Molecular Function

ganglioside galactosyltransferase activity (IEA)

glycosyltransferase activity (IEA)

hexosyltransferase activity (IEA)

transferase activity (IEA)

UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity (IBA,IEA)

References

Additional References at PubMed

PMID:15607421	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

B3GALT4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	2,719,112 - 2,720,997 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	2,800,237 - 2,801,914 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	3,050,290 - 3,052,173 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	3,050,496 - 3,052,173 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	2,717,968 - 2,719,645 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	2,799,458 - 2,801,135 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	2,874,152 - 2,875,829 (+)	NCBI		UU_Cfam_GSD_1.0

B3GALT4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	33,277,123 - 33,278,825 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	33,277,123 - 33,284,832 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	33,244,900 - 33,246,602 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	33,352,895 - 33,354,580 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	33,352,894 - 33,354,580	NCBI
Celera	6	34,799,275 - 34,800,960 (+)	NCBI		Celera
Cytogenetic Map	6	p21.32	NCBI
HuRef	6	32,986,574 - 32,988,259 (+)	NCBI		HuRef
CHM1_1	6	33,246,853 - 33,248,538 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	33,098,485 - 33,100,187 (+)	NCBI		T2T-CHM13v2.0

B3galt4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	34,168,886 - 34,170,462 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	34,168,883 - 34,170,462 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	33,949,912 - 33,951,488 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	33,949,909 - 33,951,488 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	34,086,857 - 34,088,433 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	33,560,366 - 33,561,933 (-)	NCBI		MGSCv36	mm8
Celera	17	36,702,811 - 36,704,369 (-)	NCBI		Celera
Cytogenetic Map	17	B1	NCBI
cM Map	17	17.98	NCBI

B3galt4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	4,937,974 - 4,939,549 (+)	NCBI		GRCr8
mRatBN7.2	20	4,936,089 - 4,937,664 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	4,931,768 - 4,938,315 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	5,659,611 - 5,661,186 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	5,021,356 - 5,022,931 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	5,502,143 - 5,503,718 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	5,446,104 - 5,447,679 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	5,446,104 - 5,447,673 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	7,504,716 - 7,506,291 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	5,087,855 - 5,089,430 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	5,088,110 - 5,089,652 (+)	NCBI
Celera	20	6,520,332 - 6,521,907 (+)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

B3galt4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955437	1,839,707 - 1,840,516 (+)	NCBI	ChiLan1.0	ChiLan1.0

B3GALT4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	47,754,827 - 47,756,660 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	43,626,600 - 43,628,327 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	32,849,358 - 32,857,140 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	33,963,517 - 33,965,245 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	33,962,718 - 33,964,976 (+)	Ensembl	panpan1.1		panPan2

B3galt4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	38,370,698 - 38,372,943 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	25,587,592 - 25,588,763 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936476	25,587,328 - 25,589,081 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

B3GALT4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	29,643,182 - 29,648,604 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	29,643,049 - 29,644,847 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	34,146,939 - 34,148,611 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

B3GALT4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	38,798,224 - 38,799,910 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	38,798,496 - 38,799,644 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	33,112,105 - 33,119,151 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

B3galt4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624754	23,542,500 - 23,543,855 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in B3GALT4
13 total Variants

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001080722	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005627070	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_014118044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038682748	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038682749	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ630366	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000123	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000357	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00845036965 ⟹ ENSCAFP00845028946

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	3,050,496 - 3,052,173 (+)	Ensembl

RefSeq Acc Id:

NM_001080722 ⟹ NP_001074191

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	12	2,719,320 - 2,720,997 (+)	NCBI
Dog10K_Boxer_Tasha	12	2,800,237 - 2,801,914 (+)	NCBI
ROS_Cfam_1.0	12	3,050,496 - 3,052,173 (+)	NCBI
UMICH_Zoey_3.1	12	2,717,968 - 2,719,645 (+)	NCBI
UNSW_CanFamBas_1.0	12	2,799,458 - 2,801,135 (+)	NCBI
UU_Cfam_GSD_1.0	12	2,874,152 - 2,875,829 (+)	NCBI

Sequence:

show sequence

CGGGCGGGGGAGGGGCGGCCGGCGCTGCAGCTTAATCTCGGAGCCGAGCTCGGGCGGCGAGGCC
CCGACGAGGTAACCTCCCGCAGTCCTGGCTGCGGCCCCCTCCGGCACCGGTACCCGCCGCGCGC
TCCAGCCGCCCGCTCCAGCCTAGGCGTAGCCGGTTAGGGACCCGGGGCTTCCTCCCGCTAACCG
CCTTCGTGTTTCCCTCCAGGTCACTTCTGATTACCCCACGCCATGCCCCTCAGCCTCTTTCGGC
GCCTTCTCCTTGCTGCCCTGCTGCTGGTGATTATCTGGACCCTCTTTGGGCCCTCGGGCATCGG
GGAGGAGCTGCTGAGCCTCTCTCTGGCCTCCCTGAGCCCGGCTCCCGCCTCCCCGGGGCCGCCC
CTGGCCCTGCCCCGCCTCCTGATTCCCAATGAGAAGGCGTGCGGGGGTCCCGGCTCCCCACCCT
TCCTGCTCATCCTGGTGTGCACGGCCCCAGAGAACCTGAACCAAAGAAATGCCATTCGGGCTTC
GTGGGGCGGGCTGCGCGAGGCCCAAGGGTTCCGGGTGCAGATTCTCTTTCTTTTGGGAGAGCCA
AGCTTGTGGCATCCTACCAAGGAACCCCACGACATCGACCTAGTACGGGAGGCAGCGGCCCAGG
GGGACATCTTACAGGCGGCCTTCCGGGATTCCTACCGTAACCTTACTCTCAAGACCCTCAGTGG
GCTGAACTGGGCAGACAAACACTGTTCTATGGCCCGCTACATCCTCAAGACAGATGATGATGTG
TTTGTCAACGTCCCCGAACTGGTATCAGAGCTGATTCGGCGAGGGGGCCATTGGGAACAATGGG
AGAAGGGCAAGGAGCCTCCAAGAGCGGTTAAGGCTGGAGATAAAGAGTGGGAAGAAAGGCCCAT
CTTGAAGAGCCAGCCAATGCCTCTTCTGTATCTGGGCCGTGTGCACTGGCGGGTGCACCCCTCT
CGGACACCAGGGAGCAAGCACCAGATATCGGAGGAGCAGTGGCCTCCCACCTGGGGCCCCTTTC
CACCCTATGCCTCTGGTACAGGGTACGTGCTGTCAGCTTCTGCTGTGCAGCTCATCCTAAAAGT
GGCCAGCCGGGCACCCCCTCTGCCACTGGAGGATGTCTTTGTGGGGGTGAGCGCCCGACGAGGA
GGTCTCACCCCAACCCACTGTGTTAAACTGGCTGGGGCCACCCACTACCCCTTGGACCGGTGCT
GCTATGGGAAATTCCTGCTGACATCCCACAAACTGGACCCCTGGAAGATGCAGGAAGCCTGGAA
GCTGGTGGGCGGCTCTGACGGGGAAAGGACTGCACCCTTCTGTTCCTGGCTTCAGGAAGTTTTG
GGCATCCTGCGATGTCGGGTAATAGCCTGGCTTCATAGCTGAGAGTGCCATAGTAGAGGAGTGA
GGAGCTGAGGGTCGAGCCAGCACACCCACAACCTTCTCTGGCCCAGGCCCAACACAGGGGGCCC
TGACTGGCTGCAGCTGATCGGTTTCCTCTATCAAATGCTCCATCTATCACTGAAGATGGAGGGA
CACAGGAGAAATCCAGGGGCCTGGCCTGCCAGACCTAGTGATGGTCACCAGGAAGAGCAAAACA
ATGCCGGGATTGTTCTCTCCAGCTATGGCGGGGAAGGGGCACAAGCTCCTCAATAAACTTGTCT
GTCTACCTCTTCGA

hide sequence

RefSeq Acc Id:

XM_038682748 ⟹ XP_038538676

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	12	3,050,434 - 3,052,170 (+)	NCBI

RefSeq Acc Id:

XM_038682749 ⟹ XP_038538677

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	12	3,050,290 - 3,052,170 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001074191	(Get FASTA)	NCBI Sequence Viewer
	XP_038538676	(Get FASTA)	NCBI Sequence Viewer
	XP_038538677	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAI11440	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00805018684
	ENSCAFP00845028946
	ENSCAFP00845028946.1
GenBank Protein	Q5TJE8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001074191 ⟸ NM_001080722

- UniProtKB:

Q5TJE8 (UniProtKB/Swiss-Prot), A0A8C0JP40 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPLSLFRRLLLAALLLVIIWTLFGPSGIGEELLSLSLASLSPAPASPGPPLALPRLLIPNEKAC
GGPGSPPFLLILVCTAPENLNQRNAIRASWGGLREAQGFRVQILFLLGEPSLWHPTKEPHDIDL
VREAAAQGDILQAAFRDSYRNLTLKTLSGLNWADKHCSMARYILKTDDDVFVNVPELVSELIRR
GGHWEQWEKGKEPPRAVKAGDKEWEERPILKSQPMPLLYLGRVHWRVHPSRTPGSKHQISEEQW
PPTWGPFPPYASGTGYVLSASAVQLILKVASRAPPLPLEDVFVGVSARRGGLTPTHCVKLAGAT
HYPLDRCCYGKFLLTSHKLDPWKMQEAWKLVGGSDGERTAPFCSWLQEVLGILRCRVIAWLHS

hide sequence

RefSeq Acc Id:	XP_038538677 ⟸ XM_038682749
- Peptide Label:	isoform X1
- UniProtKB:	Q5TJE8 (UniProtKB/Swiss-Prot), A0A8C0JP40 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038538676 ⟸ XM_038682748
- Peptide Label:	isoform X1
- UniProtKB:	Q5TJE8 (UniProtKB/Swiss-Prot), A0A8C0JP40 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845028946 ⟸ ENSCAFT00845036965

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00805013038	UniProtKB/Swiss-Prot
	ENSCAFG00845020962	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSCAFT00805023761	UniProtKB/Swiss-Prot
	ENSCAFT00845036965	ENTREZGENE
	ENSCAFT00845036965.1	UniProtKB/Swiss-Prot
Gene3D-CATH	3.90.550.50	UniProtKB/Swiss-Prot
InterPro	Glyco_trans_31	UniProtKB/Swiss-Prot
KEGG Report	cfa:481737	UniProtKB/Swiss-Prot
NCBI Gene	B3GALT4	ENTREZGENE
PANTHER	BETA-1,3-GALACTOSYLTRANSFERASE 4	UniProtKB/Swiss-Prot
	PTHR11214	UniProtKB/Swiss-Prot
Pfam	Galactosyl_T	UniProtKB/Swiss-Prot
UniProt	A0A8C0JP40	ENTREZGENE
	B3GT4_CANLF	UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID	VGNC:38335	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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