OR5B3 (olfactory receptor family 5 subfamily B member 3) - Rat Genome Database

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Gene: OR5B3 (olfactory receptor family 5 subfamily B member 3) Canis lupus familiaris
Analyze
Symbol: OR5B3
Name: olfactory receptor family 5 subfamily B member 3
RGD ID: 12098013
Description: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: LOC106557480; olfactory receptor 5B3-like
RGD Orthologs
Human
Mouse
Rat
Bonobo
Pig
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11838,021,824 - 38,022,762 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1838,021,824 - 38,022,762 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1837,566,301 - 37,567,239 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01838,691,704 - 38,692,642 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1838,691,704 - 38,692,642 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11838,280,463 - 38,281,401 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01837,852,783 - 37,853,721 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01838,473,615 - 38,474,553 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
OR5B3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11838,021,824 - 38,022,762 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1838,021,824 - 38,022,762 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1837,566,301 - 37,567,239 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01838,691,704 - 38,692,642 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1838,691,704 - 38,692,642 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11838,280,463 - 38,281,401 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01837,852,783 - 37,853,721 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01838,473,615 - 38,474,553 (+)NCBIUU_Cfam_GSD_1.0
OR5B3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381158,402,464 - 58,406,874 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1158,402,464 - 58,406,874 (-)EnsemblGRCh38hg38GRCh38
GRCh371158,169,937 - 58,174,347 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361157,926,514 - 57,927,458 (-)NCBINCBI36Build 36hg18NCBI36
Build 341157,926,513 - 57,927,458NCBI
Celera1155,528,361 - 55,529,305 (-)NCBICelera
Cytogenetic Map11q12.1NCBI
HuRef1154,517,702 - 54,518,646 (-)NCBIHuRef
CHM1_11158,035,909 - 58,036,853 (-)NCBICHM1_1
T2T-CHM13v2.01158,350,880 - 58,356,796 (-)NCBIT2T-CHM13v2.0
Or5b3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391913,387,935 - 13,388,864 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1913,385,213 - 13,391,904 (+)EnsemblGRCm39 Ensembl
GRCm381913,410,571 - 13,411,500 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1913,407,849 - 13,414,540 (+)EnsemblGRCm38mm10GRCm38
MGSCv371913,485,061 - 13,485,990 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361913,477,590 - 13,478,519 (+)NCBIMGSCv36mm8
Celera1914,081,942 - 14,082,871 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map198.73NCBI
Or5b3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81219,974,970 - 219,975,908 (+)NCBIGRCr8
mRatBN7.21210,550,409 - 210,551,347 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1210,546,700 - 210,552,693 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1218,924,852 - 218,925,790 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01225,816,150 - 225,817,088 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01218,679,340 - 218,680,278 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01230,268,991 - 230,269,929 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1230,268,991 - 230,269,929 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01237,405,866 - 237,406,804 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41216,505,653 - 216,506,591 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11216,664,082 - 216,665,021 (+)NCBI
Celera1207,949,619 - 207,950,557 (+)NCBICelera
Cytogenetic Map1q43NCBI
LOC100982486
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2959,553,715 - 59,558,118 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11160,579,820 - 60,584,223 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01153,644,346 - 53,645,290 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11157,107,015 - 57,107,959 (-)NCBIpanpan1.1PanPan1.1panPan2
LOC100519009
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl212,707,442 - 12,708,380 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1212,707,442 - 12,708,380 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2212,368,666 - 12,369,604 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in OR5B3
31 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system integumental system reproductive system
High
Medium
Low
Below cutoff 1 1 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000049138   ⟹   ENSCAFP00000040345
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1838,021,824 - 38,022,762 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845032991   ⟹   ENSCAFP00845025817
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1838,691,704 - 38,692,642 (+)Ensembl
RefSeq Acc Id: NM_001389167   ⟹   NP_001376096
RefSeq Status: INFERRED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1837,566,301 - 37,567,239 (+)NCBI
ROS_Cfam_1.01838,691,704 - 38,692,642 (+)NCBI
UMICH_Zoey_3.11838,280,463 - 38,281,401 (+)NCBI
UNSW_CanFamBas_1.01837,852,783 - 37,853,721 (+)NCBI
UU_Cfam_GSD_1.01838,473,615 - 38,474,553 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001376096 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000040345.1
  ENSCAFP00030027548.1
  ENSCAFP00040020024.1
  ENSCAFP00845025817
  ENSCAFP00845025817.1
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000040345   ⟸   ENSCAFT00000049138
RefSeq Acc Id: NP_001376096   ⟸   NM_001389167
- UniProtKB: A0A8C0NUR6 (UniProtKB/TrEMBL),   A0A8I3NWE2 (UniProtKB/TrEMBL),   A0A8C0QT78 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845025817   ⟸   ENSCAFT00845032991
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000030124 Ensembl
  ENSCAFG00000050563 UniProtKB/TrEMBL
  ENSCAFG00030017136 UniProtKB/TrEMBL
  ENSCAFG00040012542 UniProtKB/TrEMBL
  ENSCAFG00845018668 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000049138.2 UniProtKB/TrEMBL
  ENSCAFT00030031592.1 UniProtKB/TrEMBL
  ENSCAFT00040023099.1 UniProtKB/TrEMBL
  ENSCAFT00845032991 ENTREZGENE
  ENSCAFT00845032991.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
NCBI Gene LOC106557480 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 5B3 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8C0NUR6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0QT78 ENTREZGENE
  A0A8I3NWE2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:96850 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-04 OR5B3  olfactory receptor family 5 subfamily B member 3  LOC106557480  olfactory receptor 5B3-like  Symbol and/or name change 5135510 APPROVED