COA8 (cytochrome c oxidase assembly factor 8) - Rat Genome Database

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Gene: COA8 (cytochrome c oxidase assembly factor 8) Canis lupus familiaris
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Symbol: COA8
Name: cytochrome c oxidase assembly factor 8
RGD ID: 12097931
Description: INVOLVED IN intrinsic apoptotic signaling pathway (ortholog); mitochondrial cytochrome c oxidase assembly (ortholog); negative regulation of reactive oxygen species biosynthetic process (ortholog); ASSOCIATED WITH cytochrome-c oxidase deficiency disease (ortholog); Mitochondrial Complex IV Deficiency, Nuclear Type 1 (ortholog); Mitochondrial Complex IV Deficiency, Nuclear Type 17 (ortholog); FOUND IN matrix side of mitochondrial inner membrane (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: APOPT1; apoptogenic 1, mitochondrial; apoptogenic protein 1, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1871,324,271 - 71,357,468 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl871,318,244 - 71,357,466 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha870,836,065 - 70,868,225 (+)NCBI
ROS_Cfam_1.0871,600,822 - 71,633,185 (+)NCBI
UMICH_Zoey_3.1871,289,897 - 71,322,193 (+)NCBI
UNSW_CanFamBas_1.0871,329,474 - 71,362,251 (+)NCBI
UU_Cfam_GSD_1.0871,728,858 - 71,761,268 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
COA8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1871,324,271 - 71,357,468 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl871,318,244 - 71,357,466 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha870,836,065 - 70,868,225 (+)NCBI
ROS_Cfam_1.0871,600,822 - 71,633,185 (+)NCBI
UMICH_Zoey_3.1871,289,897 - 71,322,193 (+)NCBI
UNSW_CanFamBas_1.0871,329,474 - 71,362,251 (+)NCBI
UU_Cfam_GSD_1.0871,728,858 - 71,761,268 (+)NCBI
COA8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl14103,562,960 - 103,607,523 (+)EnsemblGRCh38hg38GRCh38
GRCh3814103,562,960 - 103,590,899 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3714104,029,297 - 104,057,236 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614103,099,084 - 103,128,277 (+)NCBINCBI36hg18NCBI36
Build 3414103,099,083 - 103,128,261NCBI
Celera1484,083,545 - 84,111,477 (+)NCBI
Cytogenetic Map14q32.33NCBI
HuRef1484,207,680 - 84,235,763 (+)NCBIHuRef
CHM1_114103,967,493 - 103,995,428 (+)NCBICHM1_1
Coa8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912111,679,394 - 111,721,491 (+)NCBIGRCm39mm39
GRCm39 Ensembl12111,679,695 - 111,721,487 (+)Ensembl
GRCm3812111,713,268 - 111,755,057 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12111,713,261 - 111,755,053 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712112,951,480 - 112,993,266 (+)NCBIGRCm37mm9NCBIm37
MGSCv3612112,161,079 - 112,181,999 (+)NCBImm8
Celera12112,907,511 - 112,957,133 (+)NCBICelera
Cytogenetic Map12F1NCBI
Coa8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26130,772,218 - 130,797,081 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl6130,771,199 - 130,797,081 (+)Ensembl
Rnor_6.06136,185,772 - 136,210,936 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.06136,279,476 - 136,304,317 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6136,279,496 - 136,304,095 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl6136,185,487 - 136,210,940 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06144,205,803 - 144,230,967 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46136,495,214 - 136,520,116 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16136,501,406 - 136,526,300 (+)NCBI
Celera6128,327,965 - 128,352,225 (+)NCBICelera
Cytogenetic Map6q32NCBI
Apopt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555382,415,604 - 2,434,658 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555382,415,781 - 2,432,742 (+)NCBIChiLan1.0ChiLan1.0
LOC100994669
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.114104,000,696 - 104,027,230 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14104,000,692 - 104,027,230 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01484,189,323 - 84,217,230 (+)NCBIMhudiblu_PPA_v0panPan3
APOPT1
(Sus scrofa - pig)
No map positions available.
LOC103229762
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12481,503,069 - 81,533,578 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2481,503,134 - 81,535,430 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605368,807,395 - 68,837,872 (+)NCBIVero_WHO_p1.0
Apopt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247341,295,053 - 1,315,620 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022422404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038484305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038484306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038545834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038545835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038596417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038596425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038609903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038609904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038674745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038674746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000049061   ⟹   ENSCAFP00000041219
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl871,333,026 - 71,357,466 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000074765   ⟹   ENSCAFP00000045069
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl871,318,244 - 71,357,250 (+)Ensembl
RefSeq Acc Id: XM_038484305   ⟹   XP_038340233
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1871,289,897 - 71,322,193 (+)NCBI
RefSeq Acc Id: XM_038484306   ⟹   XP_038340234
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1871,290,459 - 71,322,193 (+)NCBI
RefSeq Acc Id: XM_038545834   ⟹   XP_038401762
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0871,728,858 - 71,761,268 (+)NCBI
RefSeq Acc Id: XM_038545835   ⟹   XP_038401763
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0871,729,420 - 71,761,268 (+)NCBI
RefSeq Acc Id: XM_038596417   ⟹   XP_038452345
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha870,836,065 - 70,868,225 (+)NCBI
RefSeq Acc Id: XM_038596425   ⟹   XP_038452353
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha870,836,628 - 70,868,225 (+)NCBI
RefSeq Acc Id: XM_038609903   ⟹   XP_038465831
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0871,329,474 - 71,362,251 (+)NCBI
RefSeq Acc Id: XM_038609904   ⟹   XP_038465832
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0871,329,898 - 71,362,251 (+)NCBI
RefSeq Acc Id: XM_038674745   ⟹   XP_038530673
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0871,600,822 - 71,633,185 (+)NCBI
RefSeq Acc Id: XM_038674746   ⟹   XP_038530674
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0871,601,384 - 71,633,185 (+)NCBI
Reference Sequences
RefSeq Acc Id: ENSCAFP00000041219   ⟸   ENSCAFT00000049061
RefSeq Acc Id: ENSCAFP00000045069   ⟸   ENSCAFT00000074765
RefSeq Acc Id: XP_038340233   ⟸   XM_038484305
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038340234   ⟸   XM_038484306
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038465831   ⟸   XM_038609903
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038465832   ⟸   XM_038609904
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038530673   ⟸   XM_038674745
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038530674   ⟸   XM_038674746
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038452345   ⟸   XM_038596417
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038452353   ⟸   XM_038596425
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038401762   ⟸   XM_038545834
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038401763   ⟸   XM_038545835
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000030884 Ensembl
NCBI Gene APOPT1 ENTREZGENE
VGNC ID VGNC:53488 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-16 COA8  cytochrome c oxidase assembly factor 8  APOPT1  apoptogenic 1, mitochondrial  Symbol and/or name change 5135510 APPROVED