SENP3 (SUMO specific peptidase 3) - Rat Genome Database

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Gene: SENP3 (SUMO specific peptidase 3) Canis lupus familiaris
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Symbol: SENP3
Name: SUMO specific peptidase 3
RGD ID: 12097819
Description: ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); deSUMOylase activity (inferred); INVOLVED IN protein metabolic process (ortholog); ASSOCIATED WITH common variable immunodeficiency (ortholog); congenital myasthenic syndrome 2A (ortholog); dyskeratosis congenita (ortholog); FOUND IN MLL1 complex (inferred); nucleolus (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sentrin-specific protease 3; SUMO1/sentrin/SMT3 specific peptidase 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,485,738 - 32,493,225 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,484,572 - 32,500,805 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,625,628 - 32,633,084 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,591,260 - 32,598,758 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,591,119 - 32,599,040 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,558,934 - 32,566,388 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,515,387 - 32,522,853 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,694,472 - 32,701,951 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
MLL1 complex  (IEA)
nucleolus  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SENP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,485,738 - 32,493,225 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,484,572 - 32,500,805 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,625,628 - 32,633,084 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,591,260 - 32,598,758 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,591,119 - 32,599,040 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,558,934 - 32,566,388 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,515,387 - 32,522,853 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,694,472 - 32,701,951 (+)NCBIUU_Cfam_GSD_1.0
SENP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,561,919 - 7,571,969 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,561,919 - 7,571,969 (+)EnsemblGRCh38hg38GRCh38
GRCh37177,465,236 - 7,475,287 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,406,043 - 7,416,011 (+)NCBINCBI36Build 36hg18NCBI36
Build 34177,406,051 - 7,416,005NCBI
Celera177,491,642 - 7,501,608 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,359,494 - 7,369,451 (+)NCBIHuRef
CHM1_1177,474,271 - 7,484,215 (+)NCBICHM1_1
T2T-CHM13v2.0177,466,180 - 7,476,216 (+)NCBIT2T-CHM13v2.0
Senp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,563,936 - 69,572,910 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,563,941 - 69,572,910 (-)EnsemblGRCm39 Ensembl
GRCm381169,673,110 - 69,682,084 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,673,115 - 69,682,084 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,486,612 - 69,495,586 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361170,257,225 - 70,265,953 (-)NCBIMGSCv36mm8
MGSCv361169,489,313 - 69,498,041 (-)NCBIMGSCv36mm8
Celera1442,203,293 - 42,205,089 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.86NCBI
Senp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81054,889,445 - 54,898,359 (-)NCBIGRCr8
mRatBN7.21054,390,698 - 54,399,590 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1054,390,694 - 54,399,593 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1059,053,330 - 59,062,115 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01058,541,882 - 58,550,667 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01054,049,464 - 54,058,248 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01056,277,609 - 56,286,867 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,277,615 - 56,286,391 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,023,247 - 56,032,090 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,490,584 - 56,499,367 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11056,504,209 - 56,513,074 (-)NCBI
Celera1053,545,215 - 53,553,997 (-)NCBICelera
Cytogenetic Map10q24NCBI
SENP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21915,156,979 - 15,166,645 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11717,123,059 - 17,132,715 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,593,904 - 7,603,538 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1177,580,106 - 7,589,838 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,580,106 - 7,589,838 (+)Ensemblpanpan1.1panPan2
Senp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,369,933 - 47,376,761 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936595844,023 - 850,949 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936595844,073 - 850,951 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SENP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,765,187 - 52,867,576 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,857,463 - 52,867,583 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SENP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,939,231 - 6,948,831 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl166,940,281 - 6,949,221 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605914,459,577 - 14,469,180 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Senp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478610,179,557 - 10,187,416 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478610,179,604 - 10,187,416 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SENP3
47 total Variants

Expression


Sequence


RefSeq Acc Id: ENSCAFT00845041124   ⟹   ENSCAFP00845032229
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl532,591,119 - 32,599,040 (+)Ensembl
RefSeq Acc Id: XM_038475536   ⟹   XP_038331464
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1532,558,934 - 32,566,388 (+)NCBI
RefSeq Acc Id: XM_038536705   ⟹   XP_038392633
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0532,694,472 - 32,701,951 (+)NCBI
RefSeq Acc Id: XM_038600881   ⟹   XP_038456809
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0532,515,387 - 32,522,853 (+)NCBI
RefSeq Acc Id: XM_038665424   ⟹   XP_038521352
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0532,591,260 - 32,598,758 (+)NCBI
RefSeq Acc Id: XM_844542   ⟹   XP_849635
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1532,485,738 - 32,493,225 (+)NCBI
Dog10K_Boxer_Tasha532,625,628 - 32,633,084 (+)NCBI
Sequence:
RefSeq Acc Id: XP_849635   ⟸   XM_844542
- UniProtKB: A0A8C0NCN0 (UniProtKB/TrEMBL),   A0A8C0QXB2 (UniProtKB/TrEMBL),   A0A8I3PS40 (UniProtKB/TrEMBL),   A0A8P0NI73 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038331464   ⟸   XM_038475536
RefSeq Acc Id: XP_038456809   ⟸   XM_038600881
RefSeq Acc Id: XP_038521352   ⟸   XM_038665424
- UniProtKB: A0A8C0NCN0 (UniProtKB/TrEMBL),   A0A8C0QXB2 (UniProtKB/TrEMBL),   A0A8I3PS40 (UniProtKB/TrEMBL),   A0A8P0NI73 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038392633   ⟸   XM_038536705
- UniProtKB: A0A8C0NCN0 (UniProtKB/TrEMBL),   A0A8C0QXB2 (UniProtKB/TrEMBL),   A0A8I3PS40 (UniProtKB/TrEMBL),   A0A8P0NI73 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845032229   ⟸   ENSCAFT00845041124

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000016628 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030015604 UniProtKB/TrEMBL
  ENSCAFG00040005426 UniProtKB/TrEMBL
  ENSCAFG00845023301 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000026341.6 UniProtKB/TrEMBL
  ENSCAFT00000077661.2 UniProtKB/TrEMBL
  ENSCAFT00030028761.1 UniProtKB/TrEMBL
  ENSCAFT00030028833.1 UniProtKB/TrEMBL
  ENSCAFT00040010190.1 UniProtKB/TrEMBL
  ENSCAFT00040010256.1 UniProtKB/TrEMBL
  ENSCAFT00845041124 ENTREZGENE
  ENSCAFT00845041124.1 UniProtKB/TrEMBL
InterPro Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Peptidase_C48_C UniProtKB/TrEMBL
  SENP3_5_cons_dom UniProtKB/TrEMBL
KEGG Report cfa:607655 UniProtKB/TrEMBL
NCBI Gene SENP3 ENTREZGENE
PANTHER PTHR12606:SF16 UniProtKB/TrEMBL
  SENTRIN/SUMO-SPECIFIC PROTEASE UniProtKB/TrEMBL
Pfam Peptidase_C48 UniProtKB/TrEMBL
  SENP3_5_N UniProtKB/TrEMBL
PROSITE ULP_PROTEASE UniProtKB/TrEMBL
Superfamily-SCOP SSF54001 UniProtKB/TrEMBL
UniProt A0A8C0NCN0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0NIQ4_CANLF UniProtKB/TrEMBL
  A0A8C0QXB2 ENTREZGENE
  A0A8I3PS40 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NI73 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A8P0T4I1 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-02-27 SENP3  SUMO specific peptidase 3    SUMO1/sentrin/SMT3 specific peptidase 3  Symbol and/or name change 5135510 APPROVED