EDN3 (endothelin 3) - Rat Genome Database

Name: EDN3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: EDN3 (endothelin 3) Canis lupus familiaris

Analyze

Symbol:

EDN3

Name:

endothelin 3

RGD ID:

12096865

Description:

ENCODES a protein that exhibits endothelin B receptor binding (inferred); hormone activity (inferred); INVOLVED IN artery smooth muscle contraction (ortholog); cell population proliferation (ortholog); establishment of localization in cell (ortholog); PARTICIPATES IN endothelin signaling pathway; ASSOCIATED WITH Bradycardia (ortholog); congenital central hypoventilation syndrome (ortholog); genetic disease (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

endothelin-3; ET-3; PPET3; preproendothelin-3

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EDN3 (endothelin 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Edn3 (endothelin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Edn3 (endothelin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Edn3 (endothelin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	EDN3 (endothelin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Edn3 (endothelin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EDN3 (endothelin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	EDN3 (endothelin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Edn3 (endothelin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	44,024,553 - 44,054,727 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	44,033,419 - 44,054,050 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	43,279,240 - 43,297,953 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	44,892,278 - 44,922,442 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	44,901,164 - 44,921,767 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	44,002,694 - 44,021,373 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	44,121,425 - 44,140,136 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	44,781,653 - 44,800,349 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bradycardia (ISO)

congenital central hypoventilation syndrome (ISO)

genetic disease (ISO)

Hirschsprung's disease (ISO)

hypertension (ISO)

Hypotension (ISO)

Intrinsic Sleep Disorders (ISO)

sensorineural hearing loss (ISO)

Waardenburg syndrome (ISO)

Waardenburg Syndrome Type 4 (ISO)

Waardenburg syndrome type 4B (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

artery smooth muscle contraction (ISO)

axon extension (IEA)

axon guidance (IEA)

blood vessel diameter maintenance (IEA)

cell population proliferation (IEA,ISO)

cell surface receptor signaling pathway (IEA)

establishment of localization in cell (IEA,ISO)

intracellular calcium ion homeostasis (IBA,IEA,ISO)

intracellular magnesium ion homeostasis (IEA,ISO)

melanocyte differentiation (IEA,ISO)

negative regulation of hormone secretion (ISO)

neural crest cell migration (IEA,ISO)

neuron differentiation (IEA,ISO)

neuron projection development (IEA)

neutrophil chemotaxis (IEA)

peptide hormone secretion (IEA)

positive regulation of cell differentiation (IEA,ISO)

positive regulation of cell population proliferation (IEA,ISO)

positive regulation of heart rate (IEA)

positive regulation of hormone secretion (IEA)

positive regulation of leukocyte chemotaxis (IEA)

positive regulation of mitotic nuclear division (IEA)

positive regulation of potassium ion transmembrane transport (IEA,ISO)

potassium ion transmembrane transport (IEA,ISO)

regulation of cell migration (IEA,ISO)

regulation of developmental pigmentation (IEA,ISO)

regulation of gene expression (IEA,ISO)

regulation of neurotransmitter secretion (ISO)

regulation of systemic arterial blood pressure by endothelin (IBA,IEA)

regulation of vasoconstriction (IEA)

signal transduction (IEA)

vasoconstriction (IEA)

vein smooth muscle contraction (IBA,IEA)

Cellular Component

extracellular region (IEA)

extracellular space (IBA,IEA)

Molecular Function

endothelin B receptor binding (IBA,IEA)

hormone activity (IBA,IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

endothelin signaling pathway (ISO)

References

Additional References at PubMed

PMID:15528858	PMID:15838339	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

EDN3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	44,024,553 - 44,054,727 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	44,033,419 - 44,054,050 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	43,279,240 - 43,297,953 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	44,892,278 - 44,922,442 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	44,901,164 - 44,921,767 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	44,002,694 - 44,021,373 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	44,121,425 - 44,140,136 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	44,781,653 - 44,800,349 (+)	NCBI		UU_Cfam_GSD_1.0

EDN3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	59,300,611 - 59,325,992 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	59,300,443 - 59,325,992 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	57,875,666 - 57,901,047 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	57,308,894 - 57,334,442 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	20	57,308,893 - 57,334,441	NCBI
Celera	20	54,616,141 - 54,641,690 (+)	NCBI		Celera
Cytogenetic Map	20	q13.32	NCBI
HuRef	20	54,662,632 - 54,688,190 (+)	NCBI		HuRef
CHM1_1	20	57,776,830 - 57,802,379 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	61,083,933 - 61,109,315 (+)	NCBI		T2T-CHM13v2.0

Edn3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	174,602,412 - 174,625,835 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	174,602,412 - 174,625,835 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	174,760,619 - 174,784,042 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	174,760,619 - 174,784,042 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	174,586,274 - 174,609,543 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	174,403,712 - 174,426,981 (+)	NCBI		MGSCv36	mm8
Celera	2	180,720,524 - 180,743,869 (+)	NCBI		Celera
Cytogenetic Map	2	H4	NCBI
cM Map	2	98.1	NCBI

Edn3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	183,980,458 - 184,004,958 (+)	NCBI		GRCr8
mRatBN7.2	3	163,562,307 - 163,586,636 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	163,562,520 - 163,585,093 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	167,361,313 - 167,383,973 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	175,856,634 - 175,879,291 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	173,602,123 - 173,624,707 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	172,856,730 - 172,879,276 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	172,856,733 - 172,880,450 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	178,903,017 - 178,925,563 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	166,491,368 - 166,514,051 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	162,730,251 - 162,752,801 (+)	NCBI		Celera
Cytogenetic Map	3	q43	NCBI

Edn3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955445	215,859 - 237,760 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955445	215,910 - 238,153 (-)	NCBI	ChiLan1.0	ChiLan1.0

EDN3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	65,065,183 - 65,090,932 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	65,058,300 - 65,084,054 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	55,652,770 - 55,678,486 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	57,012,926 - 57,038,570 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	57,012,926 - 57,038,570 (+)	Ensembl	panpan1.1		panPan2

Edn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	181,539,619 - 181,562,016 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936530	1,744,199 - 1,765,027 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936530	1,744,216 - 1,766,602 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EDN3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	59,425,495 - 59,448,362 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	59,418,667 - 59,448,382 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	66,846,562 - 66,867,781 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EDN3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	4,814,447 - 4,839,950 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	4,814,140 - 4,839,626 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	52,860,201 - 52,885,678 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Edn3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624741	25,658,726 - 25,680,763 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in EDN3
282 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	1										5
Low	4		16		6		3		6	8	5	3
Below cutoff		5	5	5		5	3	6	6			3

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001002942	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005634662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022408799	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022408800	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022408801	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038432771	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038432772	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038432773	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038432774	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038432775	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038432776	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038432777	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038432778	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB115086	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000269	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000063	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000376	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000019450 ⟹ ENSCAFP00000018044

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	24	44,033,419 - 44,054,050 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000074727 ⟹ ENSCAFP00000063275

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	24	44,033,419 - 44,052,071 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845025428 ⟹ ENSCAFP00845020017

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	24	44,901,164 - 44,921,767 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845025445 ⟹ ENSCAFP00845020033

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	24	44,901,164 - 44,919,788 (+)	Ensembl

RefSeq Acc Id:

NM_001002942 ⟹ NP_001002942

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	24	44,033,361 - 44,052,071 (+)	NCBI
Dog10K_Boxer_Tasha	24	43,279,240 - 43,297,953 (+)	NCBI
ROS_Cfam_1.0	24	44,901,106 - 44,919,788 (+)	NCBI
UMICH_Zoey_3.1	24	44,002,694 - 44,021,373 (+)	NCBI
UNSW_CanFamBas_1.0	24	44,121,425 - 44,140,136 (+)	NCBI
UU_Cfam_GSD_1.0	24	44,781,653 - 44,800,349 (+)	NCBI

Sequence:

show sequence

CCTCAGTACCCTTTCGCGGTCACAAGCGGCCACCCTCCTGGCCCCGGTGCTCCCGCGCCTGATC
TGGGTTCTTCATGGAGCCGGGGCTGTGGCTCCTCTTCGGGCTCACGGTGACCTCCGCCGCAGGA
TTGGTACCTTGCCCCCAGCCTGGGGACGCTGGCAAAAGCGGCGTGCCCGGGACCCCCCCTACAG
CCAGATCTGAGGGGGACATCCAGGAGCCTGTGGCCATGACTGCAGTGCAAGGTCCAAGTCCCAG
AAGCCCCGAGCAGGAGCAAGAACTAGGTCGGTTTGGGGAGCAGGCATCCAAGGGGGGTCCTGTG
CACGGCCGCGCCAGGCGCTGTACCTGCTTCACATACAAGGACAAGGAGTGTGTCTACTATTGCC
ACCTGGACATCATCTGGATCAACACTCCTGAACAGACTGTGCCCTATGGACTGTCCAACTACAG
GGGGAGCTTCCGCGGCAGGAGGTCCACGGGGCTGTTCCCGCAGAGCCCACAGCCCTCCAAGTGG
ACACAGCGCTGCGCTTGTGTGCAGAGCCAGGACAGCGCCTGCTTGCACTTCTGCACCCGCACCC
TGGCTGTCAGCAGGAATTCAAGGACAGCAACAAATCCTGACAAAGAGGAAGAGCCAGCCAGCCG
TGGCAACGGGGGGCTGCGTCCAACGAGGTGAAACTTCCTTCTGAGGCATCACACCCTTGGGGAC
ATGGAGGATGTGAGGGTGGCATGTGGTCTGAGAGGTCAGCCAGCGGGAGTCCTGGCATGCATGG
GACGCTGCATCACAGGGGACTGGGCGTTGGGTAGATTGTCTCTGGGGACAAAGCAGGCTGAGGC
TAGGACAGTCAATGTCATTGCCCTTCCCCTGGCCAGTTGACCCCTTGCATCCCTTGTAGCTTTA
GAGCAGTGACACCTGGCTCTGCATTTTGCTGGGCCCAGACACAGCTAGCTGGCCACTACTGCTT
AGAGACCACCCGACCCCACCCCACCCCTGGCTCATCTACCTGGGCCCAGATGTCACTTTTTCTG
GAAGCAACATGTGGTCGTTCCACAAAAAAAAGAAATCATTTATTCTTTTCAGCAGCTGATTCTG
GACAGAAGTGAATTATAGCAGCTTGGCTTGGCAGCGAGCCCCCCATGTCCCCCCACTGGTGTTA
TTTTTTTAACCCGCTTGTCTTCTTTGTAGGAGAGATTCTGAGGGTTTCCTGCAGCCAAACTAGG
TTTATTTGTCATTCTATCAATCAGAAATTGTTATTAATGGCTCGCCTACACATCTGCAATGGGA
TGGTAATTTATGTCCATAATAATAGCCTGGAGGTGGCTTGGGTCCCTACAGGGACTGATCAAGG
GAAGATTAAACCATGCTCAGTATACAGGAGGCTTTCCAAATTGGTGGCAGTGGCTTCCAGGCAT
CCAGAGAGATCCGTCAGCATCCATAATACAAATGGAGAGGAGGGGGCGGGTGAGGCGGCCGAGA
GAGACCCCAGGAGAGCACAAGCCAGGCTCCAGCTGGTCCCTGCCTTGCCTTTTTGGTCTTTCTC
CTTTTTCTCTCTTCTCGCCCCAAACCCACACTCCTCTCAGCGAGGGCGGGATGTGATTAAAGCC
ATCCATCCTTTGCATCATTTATTCATCCACTCATGCATTCATTCAGCAAAGATGCGTCATGCAC
CTGCGTCGCGCTGGGCACTGTTCTAGAAGTCGGGTACACAACGGGGAAAAGGCGATAGGTCTGT
CTTTGCAGAATTTAAACAGAGGGAAAGCTGACAGCAGACAGATGCAGTCGTCCCCTGATCCACG
GCCTGTGGTGGACACCTGGGACCACGGGCACCATCGAGCTCTGTCTGGACTGTGTTTTCTCCTC
CACGGACACACCTATGGGAAAGTTTGATTTATAAATTGGGCACAGGAAGGAGTGACAATAACCC
ATAATCAACTAGAAGAAGCATCACAATCTACTGTAATAAAAGTTACATGAATGTGG

hide sequence

RefSeq Acc Id:

XM_038432771 ⟹ XP_038288699

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	44,901,062 - 44,922,442 (+)	NCBI

RefSeq Acc Id:

XM_038432772 ⟹ XP_038288700

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	44,901,062 - 44,919,790 (+)	NCBI

RefSeq Acc Id:

XM_038432773 ⟹ XP_038288701

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	44,901,062 - 44,919,790 (+)	NCBI

RefSeq Acc Id:

XM_038432774 ⟹ XP_038288702

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	44,892,294 - 44,922,442 (+)	NCBI

RefSeq Acc Id:

XM_038432775 ⟹ XP_038288703

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	44,892,278 - 44,922,442 (+)	NCBI

RefSeq Acc Id:

XM_038432776 ⟹ XP_038288704

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	44,898,003 - 44,922,442 (+)	NCBI

RefSeq Acc Id:

XM_038432777 ⟹ XP_038288705

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	44,892,687 - 44,922,442 (+)	NCBI

RefSeq Acc Id:

XM_038432778 ⟹ XP_038288706

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	44,894,443 - 44,922,442 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001002942	(Get FASTA)	NCBI Sequence Viewer
	XP_038288699	(Get FASTA)	NCBI Sequence Viewer
	XP_038288700	(Get FASTA)	NCBI Sequence Viewer
	XP_038288701	(Get FASTA)	NCBI Sequence Viewer
	XP_038288702	(Get FASTA)	NCBI Sequence Viewer
	XP_038288703	(Get FASTA)	NCBI Sequence Viewer
	XP_038288704	(Get FASTA)	NCBI Sequence Viewer
	XP_038288705	(Get FASTA)	NCBI Sequence Viewer
	XP_038288706	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAD07479	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000018044.3
	ENSCAFP00000063275.1
	ENSCAFP00000073535.1
	ENSCAFP00030030921.1
	ENSCAFP00030030973.1
	ENSCAFP00040032316.1
	ENSCAFP00040032389.1
	ENSCAFP00040032412.1
	ENSCAFP00040032443.1
	ENSCAFP00040032462.1
	ENSCAFP00845020017
	ENSCAFP00845020017.1
	ENSCAFP00845020033
	ENSCAFP00845020033.1
GenBank Protein	Q765Z4	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001002942 ⟸ NM_001002942
- Peptide Label:	precursor
- UniProtKB:	Q765Z4 (UniProtKB/Swiss-Prot), A0A8I3NVH8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEPGLWLLFGLTVTSAAGLVPCPQPGDAGKSGVPGTPPTARSEGDIQEPVAMTAVQGPSPRSPE QEQELGRFGEQASKGGPVHGRARRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSF RGRRSTGLFPQSPQPSKWTQRCACVQSQDSACLHFCTRTLAVSRNSRTATNPDKEEEPASRGNG GLRPTR hide sequence

RefSeq Acc Id:

ENSCAFP00000063275 ⟸ ENSCAFT00000074727

RefSeq Acc Id:

ENSCAFP00000018044 ⟸ ENSCAFT00000019450

RefSeq Acc Id:	XP_038288703 ⟸ XM_038432775
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0NQY4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038288702 ⟸ XM_038432774
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0NQY4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038288705 ⟸ XM_038432777
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0NQY4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038288706 ⟸ XM_038432778
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0NQY4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038288704 ⟸ XM_038432776
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0NQY4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038288699 ⟸ XM_038432771
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I3NPX3 (UniProtKB/TrEMBL), A0A8C0NQY4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038288700 ⟸ XM_038432772
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3NVH8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038288701 ⟸ XM_038432773
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I3NVH8 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845020033 ⟸ ENSCAFT00845025445

RefSeq Acc Id:

ENSCAFP00845020017 ⟸ ENSCAFT00845025428

Protein Domains

Endothelin-like toxin

Promoters

RGD ID:

13687678

Promoter ID:

EPDNEW_C5746

Type:

single initiation site

Name:

EDN3_1

Description:

endothelin 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	24	44,033,294 - 44,033,354	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000012245	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030019272	UniProtKB/TrEMBL
	ENSCAFG00040020082	UniProtKB/TrEMBL
	ENSCAFG00845014217	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000019450.5	UniProtKB/TrEMBL
	ENSCAFT00000074727.2	UniProtKB/TrEMBL
	ENSCAFT00000100270.1	UniProtKB/TrEMBL
	ENSCAFT00030035449.1	UniProtKB/TrEMBL
	ENSCAFT00030035510.1	UniProtKB/TrEMBL
	ENSCAFT00040037099.1	UniProtKB/TrEMBL
	ENSCAFT00040037176.1	UniProtKB/TrEMBL
	ENSCAFT00040037204.1	UniProtKB/TrEMBL
	ENSCAFT00040037239.1	UniProtKB/TrEMBL
	ENSCAFT00040037259.1	UniProtKB/TrEMBL
	ENSCAFT00845025428	ENTREZGENE
	ENSCAFT00845025428.1	UniProtKB/TrEMBL
	ENSCAFT00845025445	ENTREZGENE
	ENSCAFT00845025445.1	UniProtKB/TrEMBL
InterPro	Endothelin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Endothelin_toxin_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Endothln-like_toxin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	cfa:403406	UniProtKB/Swiss-Prot
NCBI Gene	EDN3	ENTREZGENE
PANTHER	ENDOTHELIN-3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR13874	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Endothelin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	ENDOTHELIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	ENDOTHELIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	END	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8C0NQY4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0T7Z2_CANLF	UniProtKB/TrEMBL
	A0A8C0T8L8_CANLF	UniProtKB/TrEMBL
	A0A8C0T9B8_CANLF	UniProtKB/TrEMBL
	A0A8C0T9I5_CANLF	UniProtKB/TrEMBL
	A0A8C0T9Q1_CANLF	UniProtKB/TrEMBL
	A0A8I3NPX3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3NVH8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0NE57_CANLF	UniProtKB/TrEMBL
	A0A8P0TF18_CANLF	UniProtKB/TrEMBL
	A0A8P0TSD3_CANLF	UniProtKB/TrEMBL
	EDN3_CANLF	UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID	VGNC:40201	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)