PRDX6 (peroxiredoxin 6) - Rat Genome Database

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Gene: PRDX6 (peroxiredoxin 6) Canis lupus familiaris
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Symbol: PRDX6
Name: peroxiredoxin 6
RGD ID: 12095504
Description: ENCODES a protein that exhibits 1-acylglycerophosphocholine O-acyltransferase activity (ortholog); calcium-independent phospholipase A2 activity (ortholog); glutathione peroxidase activity (ortholog); INVOLVED IN bleb assembly (ortholog); glycerophospholipid catabolic process (ortholog); hydrogen peroxide catabolic process (ortholog); ASSOCIATED WITH 1q24 Deletion Syndrome (ortholog); adult respiratory distress syndrome (ortholog); antithrombin III deficiency (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH clofibrate; phenobarbital
Type: protein-coding
RefSeq Status: MODEL
Previously known as: peroxiredoxin-6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1725,663,238 - 25,675,855 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl725,663,579 - 25,675,754 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha725,195,499 - 25,208,542 (-)NCBI
ROS_Cfam_1.0725,414,335 - 25,427,625 (-)NCBI
ROS_Cfam_1.0 Ensembl725,410,888 - 25,427,580 (-)Ensembl
UMICH_Zoey_3.1725,333,015 - 25,346,019 (-)NCBI
UNSW_CanFamBas_1.0725,411,171 - 25,424,446 (-)NCBI
UU_Cfam_GSD_1.0725,560,133 - 25,573,439 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:27306414  


Genomics

Comparative Map Data
PRDX6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1725,663,238 - 25,675,855 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl725,663,579 - 25,675,754 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha725,195,499 - 25,208,542 (-)NCBI
ROS_Cfam_1.0725,414,335 - 25,427,625 (-)NCBI
ROS_Cfam_1.0 Ensembl725,410,888 - 25,427,580 (-)Ensembl
UMICH_Zoey_3.1725,333,015 - 25,346,019 (-)NCBI
UNSW_CanFamBas_1.0725,411,171 - 25,424,446 (-)NCBI
UU_Cfam_GSD_1.0725,560,133 - 25,573,439 (-)NCBI
PRDX6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381173,477,335 - 173,488,815 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1173,477,330 - 173,488,815 (+)EnsemblGRCh38hg38GRCh38
GRCh371173,446,474 - 173,457,954 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361171,713,109 - 171,724,569 (+)NCBINCBI36hg18NCBI36
Celera1146,555,898 - 146,567,358 (+)NCBI
Cytogenetic Map1q25.1NCBI
HuRef1144,671,177 - 144,682,637 (+)NCBIHuRef
CHM1_11174,868,919 - 174,880,398 (+)NCBICHM1_1
T2T-CHM13v2.01172,835,491 - 172,846,972 (+)NCBI
Prdx6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391161,067,682 - 161,078,780 (-)NCBIGRCm39mm39
GRCm39 Ensembl1161,067,682 - 161,078,789 (-)Ensembl
GRCm381161,240,112 - 161,251,210 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1161,240,112 - 161,251,219 (-)EnsemblGRCm38mm10GRCm38
MGSCv371163,170,243 - 163,181,297 (-)NCBIGRCm37mm9NCBIm37
MGSCv361163,076,789 - 163,087,843 (-)NCBImm8
Celera1163,685,242 - 163,696,325 (-)NCBICelera
Cytogenetic Map1H2.1NCBI
cM Map169.75NCBI
Prdx6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21373,528,746 - 73,539,295 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1373,528,210 - 73,539,355 (-)Ensembl
Rnor_6.01379,077,567 - 79,088,113 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1379,077,033 - 79,088,127 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01383,972,564 - 83,983,110 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41376,824,968 - 76,835,517 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11376,838,625 - 76,849,719 (-)NCBI
Celera1373,317,100 - 73,327,649 (-)NCBICelera
Cytogenetic Map13q22NCBI
Prdx6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540613,717,267 - 13,728,216 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540613,717,267 - 13,728,216 (+)NCBIChiLan1.0ChiLan1.0
PRDX6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11152,694,606 - 152,706,521 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01148,988,836 - 149,000,345 (+)NCBIMhudiblu_PPA_v0panPan3
Prdx6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934496,376,675 - 96,386,886 (-)NCBI
SpeTri2.0NW_00493648114,223,422 - 14,233,634 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRDX6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9115,857,644 - 115,868,892 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19115,857,629 - 115,868,898 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29127,491,864 - 127,503,134 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRDX6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12555,706,920 - 55,719,196 (-)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605557,279,199 - 57,290,948 (-)NCBIVero_WHO_p1.0
Prdx6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247718,282,062 - 8,294,340 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247718,282,622 - 8,293,799 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High 2 5
Medium 3 5 22 6 6 6 6 6 12 8 5 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000023144   ⟹   ENSCAFP00000021488
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl725,663,924 - 25,675,754 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000074315   ⟹   ENSCAFP00000048834
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl725,663,846 - 25,672,042 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000088759   ⟹   ENSCAFP00000052928
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl725,663,579 - 25,672,042 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845021559   ⟹   ENSCAFP00845016941
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl725,410,888 - 25,427,580 (-)Ensembl
RefSeq Acc Id: XM_038481145   ⟹   XP_038337073
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1725,333,015 - 25,346,019 (-)NCBI
RefSeq Acc Id: XM_038542503   ⟹   XP_038398431
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0725,560,133 - 25,573,439 (-)NCBI
RefSeq Acc Id: XM_038606656   ⟹   XP_038462584
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0725,411,171 - 25,424,446 (-)NCBI
RefSeq Acc Id: XM_038671331   ⟹   XP_038527259
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0725,414,335 - 25,427,625 (-)NCBI
RefSeq Acc Id: XM_537190   ⟹   XP_537190
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1725,663,238 - 25,675,855 (-)NCBI
Dog10K_Boxer_Tasha725,195,499 - 25,208,542 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_038337073 (Get FASTA)   NCBI Sequence Viewer  
  XP_038398431 (Get FASTA)   NCBI Sequence Viewer  
  XP_038462584 (Get FASTA)   NCBI Sequence Viewer  
  XP_038527259 (Get FASTA)   NCBI Sequence Viewer  
  XP_537190 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_537190   ⟸   XM_537190
- Sequence:
RefSeq Acc Id: ENSCAFP00000052928   ⟸   ENSCAFT00000088759
RefSeq Acc Id: ENSCAFP00000048834   ⟸   ENSCAFT00000074315
RefSeq Acc Id: ENSCAFP00000021488   ⟸   ENSCAFT00000023144
RefSeq Acc Id: XP_038337073   ⟸   XM_038481145
RefSeq Acc Id: XP_038462584   ⟸   XM_038606656
RefSeq Acc Id: XP_038527259   ⟸   XM_038671331
RefSeq Acc Id: XP_038398431   ⟸   XM_038542503
RefSeq Acc Id: ENSCAFP00845016941   ⟸   ENSCAFT00845021559

Promoters
RGD ID:13683941
Promoter ID:EPDNEW_C2009
Type:initiation region
Name:PRDX6_1
Description:peroxiredoxin 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1725,675,814 - 25,675,874EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000014579 Ensembl
  ENSCAFG00845012128 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00845016941 ENTREZGENE
  ENSCAFP00845016941.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00845021559 ENTREZGENE
  ENSCAFT00845021559.1 UniProtKB/TrEMBL
InterPro AhpC/TSA UniProtKB/TrEMBL
  Peroxiredoxin_AhpC-typ UniProtKB/TrEMBL
  Peroxiredoxin_C UniProtKB/TrEMBL
  PRX_1cys UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
  Thioredoxin_domain UniProtKB/TrEMBL
NCBI Gene PRDX6 ENTREZGENE
Pfam 1-cysPrx_C UniProtKB/TrEMBL
  AhpC-TSA UniProtKB/TrEMBL
PIRSF AHPC UniProtKB/TrEMBL
PROSITE THIOREDOXIN_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/TrEMBL
UniProt A0A8I3NWQ3_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:44953 ENTREZGENE