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Gene: NOTCH2 (notch receptor 2) Canis lupus familiaris

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Symbol:

NOTCH2

Name:

notch receptor 2

RGD ID:

12093797

Description:

ENCODES a protein that exhibits calcium ion binding (inferred); cis-regulatory region sequence-specific DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN activation of protein kinase B activity (ortholog); BMP signaling pathway (ortholog); brain development (ortholog); PARTICIPATES IN Notch signaling pathway; Notch signaling pathway; ASSOCIATED WITH Acroosteolysis Dominant Type (ortholog); Alagille syndrome (ortholog); ALAGILLE SYNDROME 2 (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC111090698; neurogenic locus notch homolog protein 2; notch 2; Notch homolog 2; uncharacterized LOC111090698

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NOTCH2 (notch receptor 2)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Notch2 (notch 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Notch2 (notch receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Notch2 (notch receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NOTCH2 (notch receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	LOC101965998 (notch receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NOTCH2 (notch receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NOTCH2 (notch receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Notch2 (notch receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	NOTCH2NLR (notch 2 N-terminal like R)	HGNC	EggNOG

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	56,854,825 - 57,020,157 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	56,860,429 - 57,020,857 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	56,476,088 - 56,659,161 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	57,717,260 - 57,900,443 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	57,739,989 - 57,996,124 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	56,764,520 - 56,924,479 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	56,800,478 - 56,960,572 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	57,426,245 - 57,608,931 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Acroosteolysis Dominant Type (ISO)

Alagille syndrome (ISO)

ALAGILLE SYNDROME 2 (ISO)

autism spectrum disorder (ISO)

Breast Neoplasms (ISO)

CAKUT (ISO)

Carotid Artery Injuries (ISO)

esophagus squamous cell carcinoma (ISO)

Fibrosis (ISO)

Follicular Cyst (ISO)

Gastro-Enteropancreatic Neuroendocrine Tumor (ISO)

genetic disease (ISO)

glioblastoma (ISO)

Hajdu-Cheney syndrome (ISO)

hereditary breast ovarian cancer syndrome (ISO)

Hirschsprung Disease 1 (ISO)

Hirschsprung's disease (ISO)

IgA glomerulonephritis (ISO)

keratoacanthoma (ISO)

kidney failure (ISO)

Lung Neoplasms (ISO)

malignant astrocytoma (ISO)

Monoclonal B-Cell Lymphocytosis (ISO)

multiple myeloma (ISO)

Neoplasm Invasiveness (ISO)

PHGDH deficiency (ISO)

pre-eclampsia (ISO)

Prenatal Exposure Delayed Effects (ISO)

primary ovarian insufficiency (ISO)

Primitive Neuroectodermal Tumors (ISO)

Skin Neoplasms (ISO)

squamous cell carcinoma (ISO)

Stomach Neoplasms (ISO)

type 2 diabetes mellitus (ISO)

Uterine Cervical Neoplasms (ISO)

VACTERL association (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

activation of protein kinase B activity (ISO)

animal organ morphogenesis (IEA)

apoptotic process (IEA)

atrial septum morphogenesis (IEA)

BMP signaling pathway (IEA,ISO)

bone remodeling (IEA)

brain development (ISO)

cell differentiation (IEA)

cell population proliferation (IEA,ISO)

cellular response to tumor cell (IEA)

cholangiocyte proliferation (IEA,ISO)

ciliary body morphogenesis (IEA,ISO)

defense response to bacterium (IEA,ISO)

determination of left/right symmetry (IEA,ISO)

embryonic limb morphogenesis (IEA,ISO)

glomerular capillary formation (IEA)

heart looping (IEA)

hepatocyte proliferation (IEA,ISO)

humoral immune response (IEA,ISO)

in utero embryonic development (IEA,ISO)

inflammatory response to antigenic stimulus (IEA,ISO)

intracellular signal transduction (IEA)

intrahepatic bile duct development (IEA,ISO)

left/right axis specification (IEA)

liver development (IEA,ISO)

liver morphogenesis (IEA,ISO)

marginal zone B cell differentiation (IEA)

morphogenesis of an epithelial sheet (IEA,ISO)

multicellular organism growth (IEA,ISO)

myeloid dendritic cell differentiation (IEA,ISO)

negative regulation of gene expression (IEA)

negative regulation of transcription by RNA polymerase II (IEA,ISO)

Notch signaling pathway (IEA,ISO)

placenta blood vessel development (IEA,ISO)

placenta development (IEA,ISO)

podocyte development (IEA)

positive regulation of apoptotic process (IEA,ISO)

positive regulation of BMP signaling pathway (IEA,ISO)

positive regulation of cell population proliferation (IEA,ISO)

positive regulation of ERK1 and ERK2 cascade (IEA)

positive regulation of keratinocyte proliferation (IEA)

positive regulation of miRNA transcription (IEA)

positive regulation of osteoclast differentiation (IEA)

positive regulation of Ras protein signal transduction (IEA)

positive regulation of smooth muscle cell differentiation (IEA)

positive regulation of transcription by RNA polymerase II (IEA)

proximal tubule development (IEA)

pulmonary valve morphogenesis (IEA)

regulation of developmental process (IEA)

regulation of DNA-templated transcription (IEA)

regulation of osteoclast development (IEA)

regulation of transcription by RNA polymerase II (IEA,ISO)

tissue regeneration (ISO)

wound healing (IEA)

Cellular Component

cell surface (IEA)

cilium (IEA)

glutamatergic synapse (ISO)

Golgi apparatus (IEA)

membrane (IEA)

nucleoplasm (IEA)

nucleus (IEA)

plasma membrane (IEA)

postsynaptic density membrane (ISO)

receptor complex (IEA)

Molecular Function

calcium ion binding (IEA)

cis-regulatory region sequence-specific DNA binding (IEA)

DNA-binding transcription activator activity, RNA polymerase II-specific (IEA)

enzyme binding (IEA)

metal ion binding (IEA)

NF-kappaB binding (IEA)

protein binding (ISO)

signaling receptor activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

Notch signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

NOTCH2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	56,854,825 - 57,020,157 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	56,860,429 - 57,020,857 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	56,476,088 - 56,659,161 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	57,717,260 - 57,900,443 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	57,739,989 - 57,996,124 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	56,764,520 - 56,924,479 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	56,800,478 - 56,960,572 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	57,426,245 - 57,608,931 (-)	NCBI		UU_Cfam_GSD_1.0

NOTCH2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	119,911,553 - 120,069,662 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	119,911,553 - 120,100,779 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	120,454,176 - 120,612,276 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	120,255,699 - 120,413,799 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	120,166,219 - 120,324,318	NCBI
Celera	1	118,684,898 - 118,760,431 (-)	NCBI		Celera
Cytogenetic Map	1	p12	NCBI
HuRef	1	118,312,713 - 118,398,477 (-)	NCBI		HuRef
CHM1_1	1	120,569,670 - 120,727,793 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	119,924,810 - 120,082,923 (-)	NCBI		T2T-CHM13v2.0

Notch2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	97,920,854 - 98,057,683 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	97,920,843 - 98,057,677 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	98,013,538 - 98,150,367 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	98,013,527 - 98,150,361 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	97,817,461 - 97,954,290 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	98,098,943 - 98,232,854 (+)	NCBI		MGSCv36	mm8
Celera	3	99,412,506 - 99,549,473 (+)	NCBI		Celera
Cytogenetic Map	3	F2.2	NCBI
cM Map	3	42.42	NCBI

Notch2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	188,299,336 - 188,432,823 (+)	NCBI		GRCr8
mRatBN7.2	2	185,610,594 - 185,744,088 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	185,610,589 - 185,744,088 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	193,258,974 - 193,392,488 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	191,067,260 - 191,200,638 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	185,891,558 - 186,025,066 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	200,187,184 - 200,320,403 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	200,187,179 - 200,320,215 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	207,597,473 - 207,599,560 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	2	219,662,511 - 219,793,306 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	192,839,350 - 192,986,589 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	178,101,416 - 178,234,556 (+)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

Notch2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955568	1,660,731 - 1,809,173 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955568	1,660,357 - 1,812,285 (+)	NCBI	ChiLan1.0	ChiLan1.0

NOTCH2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	112,490,679 - 112,716,322 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	112,158,059 - 112,315,530 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	82,457,829 - 82,615,142 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	117,537,162 - 117,612,840 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	117,538,243 - 117,612,840 (+)	Ensembl	panpan1.1		panPan2

LOC101965998
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	2,620,590 - 2,684,163 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936872	390,852 - 536,321 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936872	454,273 - 539,544 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NOTCH2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	100,981,636 - 101,150,195 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	100,951,522 - 101,152,348 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	110,927,023 - 110,985,673 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NOTCH2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	13,712,140 - 13,871,777 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	13,712,292 - 13,871,784 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	16,342,675 - 16,501,918 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Notch2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624772	15,571,998 - 15,726,426 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624772	15,572,350 - 15,726,312 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in NOTCH2
1516 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005630688	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_014120603	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022404895	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022404896	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038422869	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038499365	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038561934	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038626003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000207	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000359	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000016889 ⟹ ENSCAFP00000015629

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	17	56,860,429 - 57,020,857 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845012979 ⟹ ENSCAFP00845010116

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	17	57,739,989 - 57,996,124 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845013210 ⟹ ENSCAFP00845010265

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	17	57,739,989 - 57,901,056 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845013400 ⟹ ENSCAFP00845010396

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	17	57,739,989 - 57,833,884 (-)	Ensembl

RefSeq Acc Id:

XM_005630688 ⟹ XP_005630745

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	17	56,859,738 - 57,020,157 (-)	NCBI
Dog10K_Boxer_Tasha	17	56,476,088 - 56,659,161 (-)	NCBI

Sequence:

show sequence

GGACCCCCTCCTCATATGGATCTGCGCGGGCGGTTGCGGCGGCGGCGGCGGCGGCGACCGAGAA
GATGCCCGGCCTGAGCCCCGCTCGGCTGTGGGCGCTGCTGGCGCTCGGGCTGAGCTGCGCGGCC
CCCGCGCGCGCATTGCAGTGTCGGGATAGCTATGAGCCCTGTGTAAATGAAGGAGTATGTGTTA
CCTACCACAATGGCACAGGATACTGCAAATGTCCAGAGGGTTTCTTGGGAGAATATTGTCAACA
TCGAGACCCCTGTGAGAGGAACCGCTGCCAGAATGGTGGGACGTGTGTGGCCCAGGCCATGTTG
GGGAAAGCAACATGCCGATGTGCCCTGGGGTTCACAGGTGATGATTGCCAGTACTCAACCACTC
ATCCCTGCTTTGTTTCTCACCCCTGCTTGAATGGAGGCACCTGCCACATGCATAGCCGGGATGA
CTATGAGTGCACCTGCCAAGTTGGTTTTACAGGTAAGCTGTGCCAGTGGACTGATGCCTGCCTG
TCTCATCCCTGTGCGAATGGAAGTACCTGTACCACTGTGGCCAACCAGTTCTCCTGCAAATGCC
TCACAGGCTTCACCGGACAGAAGTGTGAGATTGATGTCAATGAGTGTGACATTCCAGGACAGTG
CCAGCATGGTGGCACCTGCCTCAATCTACCGGGTTCCTATCAGTGCCAGTGCCCCCAGGGCTTC
ACAGGCAAGCACTGTGACAGCCCCTATGTGCCCTGTGCACCCTCCCCCTGTGTTAATGGTGGCA
CCTGCCGGCAGACTGGTGACTTCACATTTGAATGCAACTGCCTTCCAGGTTTTGAAGGGATCAC
CTGTGAGCGGAATATTGATGACTGCCCTAACCACAAGTGTCAGAATGGAGGGGTTTGTGTGGAT
GGGGTTAATACTTACAACTGCCGCTGTCCCCCTCAGTGGACAGGACAGTTCTGCACAGAGGATG
TGGATGAGTGTCTGCTACAACCTAATGCTTGTCAGAATGGAGGCACCTGTACCAACCGCAATGG
GGGTTATGGCTGTGTATGTGTTAATGGCTGGAGTGGAGATGACTGCAGTGAGAACATTGATGAC
TGTGCCTTTGCCTCCTGCACCCCGGGCTCCACCTGCATTGACCGTGTGGCCTCCTTCTCTTGCA
TGTGCCCAGAAGGAAAGGCAGGTCTATTATGTCATCTGGATGATGCATGCATCAGCAATCCTTG
CCACAAGGGGGCACTGTGTGATACCAACCCCCTGAACGGGCAGTATATTTGCACCTGCCCTCAA
GGCTTCAAAGGGGCTGATTGTACAGAAGATGTGGATGAGTGTGCTATGGCCAATAGCAATCCTT
GTGAGCATGCAGGAAAGTGTGTGAACACAGATGGTGCCTTCCACTGTGAATGTCTGAAGGGCTA
TGCAGGGCCTCGTTGTGAGATGGACATCAATGAGTGTCATTCCGACCCCTGCCAGAATGATGCA
ACCTGTCTGGATAAGATTGGAGGCTTCACATGTTTGTGCATGCCAGGTTTCAAAGGTGTACATT
GTGAATTGGAGATAAACGAATGTCAGAGCAACCCTTGTGTGAACAATGGTCAGTGTGTGGATAA
AGTCAATCGCTTCCAGTGTCTATGTCCACCTGGTTTCACTGGGCCAGTTTGCCAGATTGATATT
GATGACTGTTCCAGTACTCCATGTCTGAATGGGGCAAAGTGTATTGATCACCCGAATGGCTATG
AATGCCAGTGTGCCACAGGATTCACTGGTGTGTTGTGTGAGGAGAACATTGACAACTGTGACCC
TGATCCTTGCCACCATGGCCAGTGTCAGGATGGGATTGATTCCTACACCTGCATCTGCAACCCG
GGGTACATGGGTGCCATCTGCAGTGACCAGATAGATGAGTGTTACAGCAGCCCCTGCCTGAATG
ATGGTCGCTGCATTGACCTGGTGAATGGCTACCAGTGCAACTGCCAGCCTGGCACATCAGGTGT
TAATTGTGAAATCAATTTTGATGACTGTGCAAGTAACCCTTGTGTCCATGGGGTCTGTATGGAT
GGCATTAATCGTTACAGTTGTGTCTGCTCACCAGGATTCACAGGACAGAGATGTAACATTGACA
TTGATGAGTGTGCCTCCAATCCCTGTCGCAAGGGTGCAACATGCATCAATGATGTGAATGGTTT
CCGCTGTCTATGCCCTGAGGGTCCTCATCGCCCCAGCTGCTACTCACAGGTGAACGAGTGCCTG
AGCAGTCCCTGCATCCATGGAAACTGTACCGGGGGCCCTAGTGGATACAAGTGCCTTTGTGATG
CAGGCTGGATTGGTATCAACTGCGAAGTGGACAAGAATGAATGTCTTTCTAACCCATGCCAGAA
TGGAGGAACTTGTGACAATCTGGTGAATGGATACAGGTGTACTTGCAAGAAGGGCTTTAAAGGC
TATAACTGTCAGGTGAATATTGATGAATGTGCTTCAAATCCGTGTCTGAACCAAGGAACCTGCT
TTGATAACATAAGTGGCTACACTTGCCACTGTGTGCTGCCATACACAGGCAAGAATTGTCAGAC
GGTATTGGCTCCCTGTTCCCCAAACCCATGTGAGAATGCTGCTGTTTGCAAAGAGGCACCCGAT
TTTGAGAGTTACACCTGCCTGTGTGCCCCTGGCTGGCAAGGTCAGCGGTGTACAATTGACATTG
ATGAATGTGTCTCCAAACCCTGCATGAACCATGGTCTCTGCCATAATACCCAGGGCAGCTACAT
GTGCGAGTGTCCTCCGGGCTTCAGTGGTATGGACTGTGAGGACGACATCGATGACTGTCTTGCC
AATCCTTGCCAGAATGGAGGTTCCTGTGTAGATGGAGTGAATACTTTCTCCTGCCTGTGTCATC
CTGGCTTTATTGGAGATAAGTGTCAAACAGACATGAATGAGTGTCTGAGTGAACCCTGTAAGAA
TGGAGGGACTTGCTCTGACTATGTCAACAGTTACACTTGCAAGTGCCAGGCGGGATTTGATGGA
GTACACTGTGAGAACAACATCGACGAGTGCACTGAGAGCTCCTGTTTCAATGGTGGCACATGTG
TCGACGGGATTAACTCCTTCTCTTGCTTGTGCCCTTTGGGCTTTACTGGCCCCTTCTGCCTCCA
TGAGATCAATGAATGCAACTCTCACCCATGCCTAAATGAAGGAATATGTGTTGATGGCCTTGGT
ACCTACCGCTGCACCTGTCCCTTAGGCTACACTGGGAAAAACTGTCAGACACTGGTGAACCTCT
GTAGTCGGTCTCCATGTAAAAACAAAGGTACTTGCATTCAGGAAAAAGCAGAGTCCCGGTGCCT
GTGTCCATCAGGATGGGCTGGTGCTTACTGTGACGTGCCCAATGTGTCCTGTGAGGTGGCGGCC
TTACACAGAGGGGTGTCCACTGACCACCTGTGCCAGCACTCCGGCATCTGCATCAATGCTGGCA
ACTCGCATCACTGCCAGTGCCCCCTGGGCTACACCGGGAGCTACTGTGAGGAGCAGCTCGATGA
GTGCTCATCCAACCCCTGCCAGCATGGGGCCACCTGCAGGGACTTCATTGGCGGGTACAGATGT
GAGTGTGTCCCAGGATATCAGGGCGTCAATTGCGAGTATGAAGTAGATGAGTGTCAGAATCAGC
CATGCCAGAACGGAGGCACCTGTGTCGACCTCGTGAACCATTTCAAGTGCTCCTGTCCACCAGG
CACTCGAGGCCTGCTTTGTGAAGAGAACATTGATGACTGTGTTGGGGGTCCCCACTGCCTCAAT
GGTGGTCAGTGTGTGGATAGGATTGGGGGCTACAGTTGTCGCTGCTTGCCTGGCTTTGCGGGAG
AGCGGTGTGAGGGCGACATCAACGAGTGCCTCTCGAACCCCTGCAGCTCTGAGGGCAGCCTGGA
CTGCATCCAGCTAACCAATGACTACCTGTGTGTCTGTCGCAGTGCCTTCACTGGTCGTCACTGT
GAAACTTTCATCGATGTGTGTCCCCAGATGCCTTGTCTGAATGGGGGGACGTGTGCTGTGGCCA
GCAACATGCCTGATGGTTTCATTTGTCGTTGTCCCCCGGGATTCTCCGGAGCGAAATGTCAGAG
CAGCTGTGGACAAGTGAAGTGCAGGAGAGGAGAGCAGTGTGTGCACACGGCCTCAGGACCACGC
TGCTTCTGCCCCAACCCCCAGGACTGTGAATCAGGCTGTGCCAGTAGTCCCTGCCAACACGGGG
GTAGCTGCTATCCTCAGCGCCAGCCTCCTTACTACTCTTGCCAGTGTTCTCCACCATTCTGGGG
TAGCCATTGTGAACTTTACATGGCTCCCACCAGCACCCCTCCTGCCACCTGCCTGAGCCAGTAT
TGTGCCGACAAAGCTCGGGACGGCGTCTGCGATGAGGCCTGCAACAGCCATGCCTGCCAGTGGG
ATGGGGGTGACTGTTCCCTGACCATGGAGAACCCCTGGGCCAACTGCTCTTCCCCACTCCCCTG
CTGGGATTACATCAACAACCAGTGTGATGAGCTGTGCAACACAGCGGAGTGCCTTTTTGACAAT
TTTGAATGCCAGGGGAACAGCAAGACATGCAAGTATGACAAATACTGTGCAGACCACTTCAAAG
ACAACCACTGTGACCAGGGATGCAACAGTGAGGAGTGTGGCTGGGATGGGCTGGACTGTGCTGC
TGACCGGCCAGAGAACCTGGCAGAGGGGACCCTGGTTATAGTGGTGCTCATGCCCCCAGAGCAA
CTGCTCCAGGATGCCCGCAGCTTCTTGCGGGCACTGGGCACCCTGCTCCATACCAACCTGCACA
TTAAACGGGACTCCCAGGGGGCACTCATGGTCTACCCCTATTATGGTGAGAAGTCAGCTGCCAC
AAAGAAGCAGAGGATGACTCGCAGATCCCTTCCCGGTGATCAAGAACAAGAGGTGGCTGGCTCT
AAGGTATTTCTGGAAATTGACAACCGCCAGTGTGTTCAAGATTCAGACCAATGTTTCAAGAACA
CAGATGCAGCAGCAGCTCTTCTGGCTTCTCACGCCATCCAAGGGACCTTGTCCTACCCTCTTGT
ATCTGTTGTCAGTGAATCTCTGAATCCAAAACCCACTCAGCTTCTTTATCTACTTGCTGTCGCT
GTCGTCATTATCCTATTTATTATCCTGCTGGGAGTTATCATGGCCAAAAGAAAACGTAAGCATG
GCTCCCTCTGGCTGCCTGAAGGTTTCACCCTTCGCCGAGACTCCAGCAATCACAAGCGTCGTGA
ACCAGTGGGACAAGATGCCGTGGGGCTGAAAAATCTCTCAGTGCAAGTCTCAGAGGCTAACCTA
ATTGGTTCTGGAACAAGTGAACATTGGGTTGATGATGAAGGGCCCCAGCCAAAGAAAGCCAAGG
CTGAAGATGAAGCTTTGCTCTCAGAAGAAGATGATGCCATTGATCGACGTCCATGGACACAGCA
GCACCTTGAGGCTGCAGATATCCGCAGGACACCATCACTGGCACTCACTCCTCCACAGGCAGAG
CAGGAGGTGGACGTGCTGGATGTGAATGTCCGTGGCCCAGATGGGTGCACCCCATTGATGCTGG
CTTCTCTCCGAGGAGGCAGCTCAGATATGAGTGATGAAGATGAAGACGGAGAAGACTCTTCTGC
CAACATCATCACAGACTTGGTCTACCAGGGTGCCAGCCTGCAGGCCCAGACAGACCGGACTGGT
GAGATGGCCCTGCACCTTGCAGCCCGCTACTCCAGGGCTGATGCTGCCAAGCGTCTCTTGGATG
CAGGTGCAGATGCCAATGCACAGGACAACATGGGCCGTTGCCCTCTCCATGCTGCAGTGGCAGC
TGATGCCCAGGGGGTCTTCCAGATTCTGATCCGCAACCGAGTAACTGATTTGGATGCCAGGATG
AACGACGGCACTACACCGCTGATCCTGGCTGCCCGCCTAGCTGTGGAGGGAATGGTGGCAGAAC
TAATCAACTGCCAAGCAGATGTGAATGCAGTGGATGACCATGGGAAATCTGCTCTTCACTGGGC
AGCTGCTGTCAATAACGTGGAGGCAACCCTTTTGCTGTTGAAAAATGGGGCCAACCGAGACATG
CAAGACAACAAGGAAGAGACACCTCTGTTTCTTGCTGCCCGGGAGGGAAGCTATGAAGCAGCCA
AGATCCTGTTAGACCATTTTGCCAATCGGGACATCACAGACCATATGGATCGTCTTCCCCGGGA
TGTGGCTCGGGACCGCATGCACCATGACATCGTGCGCCTCCTGGATGAGTACAATGTGACGCCA
AGCCCTCCAGGCACTGTGCTGACTTCTGCACTCTCACCTGTCATCTGTGGGCCCAACAGATCTT
TCCTCAGCCTAAAGCATACCCCCATGGGCAAGAAGCCTAGACGGCCCAATACCAAGAGTACCAT
GCCTACCAGCCTCCCTAACCTTGCCAAGGAGGCCAAGGATGCCAAGGGTAGTAGGAGGAAGAAG
TCTCTGAGTGACAAGGGTCAGCTGTCTGAGAGCTCAGTGACCTTATCCCCCGTTGATTCCTTAG
AGTCTCCTCACACATATGTTTCTGACACCACATCCTCTCCAATGATCACATCCCCTGGAATCTT
ACAGGCCTCACCCAACCCTATGTTGGCCACCGCTGCCCCCCCTGCCCCAGCCCATGCTCAGCAT
GCACTGTCCTTCTCTAACCTGCATGAAATGCAGCCGTTGGCTCATGGTGCCAGCACTGTGCTTC
CCTCAGTTAGCCAGCTGCTGTCCCACCACCACATTGCTCCCCCAGGCAACGGCAGTGCAGGGAG
CTTGGGTAGGCTCCATCCTGTCACTGTTTCGGCAGATTGGATGAACCGCATGGAGATGAATGAG
ACCCAGTACAATGAGATGTTTGGTATGGTTCTGGCTCCAGCTGAGAGCACGCATCCTGGCATAC
CTCCCCAGAGCAGGCCGCCTGAAGGGAAGCACATAACTACCCCTCGGGAACCTTTGCCCCCCAT
TGTGACTTTCCAGCTAATCCCCAAAGGCAGTATTGCCCAACCAGCAGGGACTCCCCAGCCTCAG
TCTAACTGCCCTCCACCTGTTGCAGGCCCTATGCCCACCATGTATCAGATTCCAGAAATGGCTC
GTTTGCCCAGTATGGCTTTCCCCACTGCCATGGTGCCGCAGCAGGATGGGCAGGTTGCTCAGAC
CATTCTCCCAGCCTATCATCCTTTTCCGGCATCTGTGGGCAAGTATCCCACACCACCTTCACAG
CATAGTTATGCTTCCTCAAATGCTGCTGAGCGAACACCTAGTCACAGTGGTCACCTCCAGGGTG
AGCATCCCTACCTGACACCATCCCCAGAGTCTCCTGACCAGTGGTCAAGTTCATCACCCCACTC
TGCTTCTGACTGGTCAGATGTGACCACCAGCCCTACCCCTGGGGGTGCTGGAGGAGGTCAGCGG
GGACCTGGAACACACATGTCTGAGCCACCACGCAGCAACATGCAGGTTTATGCATGAAAGAGCC
TGCCTCCAGTGTAGGGACAGAGCTGCCTATTATAAATGCTGCTGAGGAACAAATGAAGGTCATC
CGGGAGAGAAATGAAGAAATCTCTGGAACTAGCTTCTGGAGGCAGGAGAAAGAAGATGCTTTTA
TCTTTTAGATAATGCAAGGGAAGCAATTTTGTCAGCTTCACTGGCTATCTGCAGGATTGGGGTG
GGGGGAACATGGCTCTTTTAATCTTTTACCCATCAAGCCAAGTTTGTGGAAATGCAAAACAAAT
ATAAGACCTGGGACCATGTTTACTCTTTTCTTTTGGAGAAAAGAATGGATGCCTATTGTAGCCC
AGACATTCTTGCATCTTGGGCTGCATTTTAAGCCCTGGGGGTGTCTGCCATATCCTTGAGAAGA
GAAGACTCTACAGTACAGTCCTTTTGGGCTTGGACCCTGGAATTCTGCCTAAGTTGACCTGTCT
CACCTTCCTTGGAAATTCTTTTGACTTCGTTTGGTGCTTTACATTTTGCACCTCTCTGTGGTTG
TGCAGCCCCACCCACCGGCATGTTACAGGACAAGACCTTTGTGCTTTTAATCATTCCTTTTCTG
GAAAGCAACTTCACCCTCCTTTCCCAGTGTCCCCAGGAGTCTCACAGGGTTTGCTTTGGTTGTA
GTTCTCAGCATATACCTTTCAAGTATGTTTCTTTAGAAAATGAATCTATTGCAGTCTCTTATGT
AATATCATTCCTAGAAGAGGAAGGGGAGCAAGATAGTTTTCTTTGAACCCATCCTGGGGACAGA
AGACCCTTTGAAAAGACTGCCTTAATTCTCTTGCCTGCATGCAGGGCTTTCTATAAACTTTACC
AGGAAGAGGGATGAGAATTTTTTCTTTTCTATTTGTGGACCTAGTCAGTGTGAAGTTTTGTTGT
TGGCAGTGCAGGTACTGTGCCCCCCTAAACAAAACAAAACTAAGATTTGGAGTGTCAGAATGAC
CAAGAGACACGTTAACTCATGGGAGAAGTGGTTACCACTAACAAGACCCTTCCTGCCTACCATT
CCACTGTCAGCTTGTGTGAAACGTATTTGTTCCCAGATCTCAGAACCCCCAGCCTGCTTCACTC
ACTCATCCAGCAGGGGAAGCTAGCCTTAGCTGTTGAGCCTTTCCTTCCAGGTATCTCCATAGAA
GACTATGTCTCAAACGATGCTCCCTCGCCACTGAGAACTGAATTCTGCTTAGCTGGAGGGATCC
CATGACAGCTGTGTTCCTTTTGTGGTGCGGTTGCAGTCTCCTTTCTGACTGTTTGCCTGCTCAC
CAGGCTTCCCTCTCCACAGCGTGCTCGGAGTTATTTGTGCAACTAAGTAGGTTCTTGCCAAACA
CATGGGTTTTCTATGTTCAAGCAAGCTGGCCTGGTTTTCTAGGGTCCTCGCCAGCCCTATTAGA
AAGTTGAAACCATGAGGCAGCCTTTGCTGTTTGTTGCTACCATTTTTTTCCTTTATGGCAGTCA
TGACATTCCCTTTTAGGCAATGAATGTAGAAGCTTATCGGGACATTTTCCTTTCCTAGATTCAC
TTTCTAGATGATGATGGACAATGAAAGACTTAACTGTCTTTATCATGCTCATGCTGAGATTGTG
ATTATATTGTACTTGAGTCTGCTTCCTGCATTTGTGGTCTTGGCACCTTCCATGACCCCCTGTC
AAGGGCAGAAGCATTCTAGTCAACACTAGAAATAGGAGGAAAAGTTTTCTTCCTCTTCTCCCTG
AGTCAGCTAATAGTTGGTCCTGTGATCATACTGTCATCTCTACCTGGTGCTATGATGTCATGAC
ACCTGGGAAATTAGTTCTGCTGGGGCATTTTGTAGATATTGACAGGGAAATTTCCTATTCTGTT
TTGGTTTGAATGATGGTCTTTATTCCTTCCTTGGCTAGGAGTGCTCATCAGAGCATCCCACTTA
ACCTGATTTCTCTGTGGCCTCCTGTATAACCCCTAGATGTCTGTTAACATGACAATCTACAGAT
TTTTTTTTCAGTCCTGCCCAAGTTCATCAAGCCAACAAAAATAATTAGTTCTGCCTCAATATGA
ACATACTGTTTGTTCATTCTATATTTTATTTGTCATGTGGCAACTCAACCAGTCCTTTCATAGT
GTGTACCATTTTATCTTCTGAATACCGACTCTCTATCCTTGGACCCATTGTTAATTCAGATGGG
GAGAACTTCTCTGCATGGACCACTGTGAACCCCACCACATATGCCCCTCTCTGTTATTCCATCT
CATCCCCATTACCTGAAAGTATCAGCCTCTGACCCAACAGCTTGGATCCTCTCTGGCCTCCTCC
CTCCCCAGCCACAGTGTAGGCCTAACTTGCTTGTTTCTCCTTCTTGGGATTCTTAGGGCTTGGG
GGAAGGGGATGTGAAAGCTGCCATTACATACAACAGGCTTCAGTATTGAGGAAGAAGACACTGC
CTTTCAAGCATTTATCAATCCCTTAGATTTTGAGAACCTTGAGTTGTATAGCACCTAATAAAAG
AGAAGGTGAGTTGGAGAACCACTTTCTCATTTGGCTTCTGAATTAGAGACTAAGTTTTTATAGG
ATGTATCTTTTATGCCATGTATAGATCACCTTCCTTCCCCTATCATTTTTGGTTTATTTTTATT
TTTATAAATTCTTCTTTTGACTCCTCTTCTGTCTACCTTTGGGGATAGATTTTTCTGTTTGTTT
CTTCTGTTTTGTGTTAAGCATCATTTTCTGACTTACATGTTGGTAAGGGAAGGAAAAGTGTAAG
GGAAAGAGAGAGTGAAAGACTTTGATGTATGCAATCAACCGTGATGCTCAAGCCCATTATACTA
TCTTGTTATTATATTTGCTGGTGCACAATTCTTGCATAGAAAAGAACCAAAGGTATGTTTTGTT
GGCAGGCAGTTTGGAGATTGTGGTTTTAACCAACACATTGAATGTATAATGATCATTTGAGAGG
ACACAGTTAAAAGACCTGATGCTCCCACTTGTAACTGTTTGGTACTATGGCGCTCCTTCCTTGT
GTACATTTCTCTTAAAAGTGATATTATATCTGTTTGTATGAGAAACCCAGTAACCAAGAAAAAT
GACTGCATGTTCCTAACTATGACACAGTAAGGAAAATGCACAATGTTTTTACTTTTCAAAGTTT
CATTCAAAGTAGTTAAGATGAAATTCATATGAAAACATTTTTATCACAAAATAAAGATTACATG
TCAAACTC

hide sequence

RefSeq Acc Id:

XM_038422869 ⟹ XP_038278797

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	17	57,717,260 - 57,900,443 (-)	NCBI

RefSeq Acc Id:

XM_038499365 ⟹ XP_038355293

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	17	56,764,520 - 56,924,479 (-)	NCBI

RefSeq Acc Id:

XM_038561934 ⟹ XP_038417862

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	17	57,426,245 - 57,608,931 (-)	NCBI

RefSeq Acc Id:

XM_038626003 ⟹ XP_038481931

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	17	56,800,478 - 56,960,572 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005630745	(Get FASTA)	NCBI Sequence Viewer
	XP_038278797	(Get FASTA)	NCBI Sequence Viewer
	XP_038355293	(Get FASTA)	NCBI Sequence Viewer
	XP_038417862	(Get FASTA)	NCBI Sequence Viewer
	XP_038481931	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000015629.5
	ENSCAFP00000068291.1
	ENSCAFP00000070065.1
	ENSCAFP00040024206.1
	ENSCAFP00845010116.1
	ENSCAFP00845010265
	ENSCAFP00845010265.1
	ENSCAFP00845010396.1

RefSeq Acc Id:	XP_005630745 ⟸ XM_005630688
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0SR20 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPGLSPARLWALLALGLSCAAPARALQCRDSYEPCVNEGVCVTYHNGTGYCKCPEGFLGEYCQH RDPCERNRCQNGGTCVAQAMLGKATCRCALGFTGDDCQYSTTHPCFVSHPCLNGGTCHMHSRDD YECTCQVGFTGKLCQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCEIDVNECDIPGQC QHGGTCLNLPGSYQCQCPQGFTGKHCDSPYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGIT CERNIDDCPNHKCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCTNRNG GYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPC HKGALCDTNPLNGQYICTCPQGFKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY AGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDK VNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDP DPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGV NCEINFDDCASNPCVHGVCMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINDVNGF RCLCPEGPHRPSCYSQVNECLSSPCIHGNCTGGPSGYKCLCDAGWIGINCEVDKNECLSNPCQN GGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDNISGYTCHCVLPYTGKNCQT VLAPCSPNPCENAAVCKEAPDFESYTCLCAPGWQGQRCTIDIDECVSKPCMNHGLCHNTQGSYM CECPPGFSGMDCEDDIDDCLANPCQNGGSCVDGVNTFSCLCHPGFIGDKCQTDMNECLSEPCKN GGTCSDYVNSYTCKCQAGFDGVHCENNIDECTESSCFNGGTCVDGINSFSCLCPLGFTGPFCLH EINECNSHPCLNEGICVDGLGTYRCTCPLGYTGKNCQTLVNLCSRSPCKNKGTCIQEKAESRCL CPSGWAGAYCDVPNVSCEVAALHRGVSTDHLCQHSGICINAGNSHHCQCPLGYTGSYCEEQLDE CSSNPCQHGATCRDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCVDLVNHFKCSCPPG TRGLLCEENIDDCVGGPHCLNGGQCVDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLD CIQLTNDYLCVCRSAFTGRHCETFIDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGAKCQS SCGQVKCRRGEQCVHTASGPRCFCPNPQDCESGCASSPCQHGGSCYPQRQPPYYSCQCSPPFWG SHCELYMAPTSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPC WDYINNQCDELCNTAECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAA DRPENLAEGTLVIVVLMPPEQLLQDARSFLRALGTLLHTNLHIKRDSQGALMVYPYYGEKSAAT KKQRMTRRSLPGDQEQEVAGSKVFLEIDNRQCVQDSDQCFKNTDAAAALLASHAIQGTLSYPLV SVVSESLNPKPTQLLYLLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDSSNHKRRE PVGQDAVGLKNLSVQVSEANLIGSGTSEHWVDDEGPQPKKAKAEDEALLSEEDDAIDRRPWTQQ HLEAADIRRTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDMSDEDEDGEDSSA NIITDLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAA DAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWA AAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITDHMDRLPRD VARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMGKKPRRPNTKSTM PTSLPNLAKEAKDAKGSRRKKSLSDKGQLSESSVTLSPVDSLESPHTYVSDTTSSPMITSPGIL QASPNPMLATAAPPAPAHAQHALSFSNLHEMQPLAHGASTVLPSVSQLLSHHHIAPPGNGSAGS LGRLHPVTVSADWMNRMEMNETQYNEMFGMVLAPAESTHPGIPPQSRPPEGKHITTPREPLPPI VTFQLIPKGSIAQPAGTPQPQSNCPPPVAGPMPTMYQIPEMARLPSMAFPTAMVPQQDGQVAQT ILPAYHPFPASVGKYPTPPSQHSYASSNAAERTPSHSGHLQGEHPYLTPSPESPDQWSSSSPHS ASDWSDVTTSPTPGGAGGGQRGPGTHMSEPPRSNMQVYA hide sequence

Ensembl Acc Id:

ENSCAFP00000015629 ⟸ ENSCAFT00000016889

RefSeq Acc Id:	XP_038355293 ⟸ XM_038499365
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038481931 ⟸ XM_038626003
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038278797 ⟸ XM_038422869
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0SR20 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038417862 ⟸ XM_038561934
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0SR20 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845010265 ⟸ ENSCAFT00845013210

Ensembl Acc Id:

ENSCAFP00845010396 ⟸ ENSCAFT00845013400

Ensembl Acc Id:

ENSCAFP00845010116 ⟸ ENSCAFT00845012979

Protein Domains

EGF-like LNR

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000010476	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00040015083	UniProtKB/TrEMBL
	ENSCAFG00845007331	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000016889.5	UniProtKB/TrEMBL
	ENSCAFT00000098380.1	UniProtKB/TrEMBL
	ENSCAFT00000099350.1	UniProtKB/TrEMBL
	ENSCAFT00040027874.1	UniProtKB/TrEMBL
	ENSCAFT00845012979.1	UniProtKB/TrEMBL
	ENSCAFT00845013210	ENTREZGENE
	ENSCAFT00845013210.1	UniProtKB/TrEMBL
	ENSCAFT00845013400.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.20	UniProtKB/TrEMBL
	3.30.300.320	UniProtKB/TrEMBL
	3.30.70.3310	UniProtKB/TrEMBL
	Laminin	UniProtKB/TrEMBL
InterPro	Ankyrin_rpt	UniProtKB/TrEMBL
	Ankyrin_rpt-contain_sf	UniProtKB/TrEMBL
	DUF3454_notch	UniProtKB/TrEMBL
	EGF-like_Ca-bd_dom	UniProtKB/TrEMBL
	EGF-like_CS	UniProtKB/TrEMBL
	EGF-like_dom	UniProtKB/TrEMBL
	EGF-type_Asp/Asn_hydroxyl_site	UniProtKB/TrEMBL
	EGF_Ca-bd_CS	UniProtKB/TrEMBL
	Growth_fac_rcpt_cys_sf	UniProtKB/TrEMBL
	Notch	UniProtKB/TrEMBL
	Notch-like_dom_sf	UniProtKB/TrEMBL
	Notch/Slit_guidance	UniProtKB/TrEMBL
	NOTCH1_EGF-like	UniProtKB/TrEMBL
	Notch_2	UniProtKB/TrEMBL
	Notch_Cell-Fate_Det	UniProtKB/TrEMBL
	Notch_dom	UniProtKB/TrEMBL
	NOTCH_homolog	UniProtKB/TrEMBL
	Notch_NOD_dom	UniProtKB/TrEMBL
	Notch_NODP_dom	UniProtKB/TrEMBL
NCBI Gene	NOTCH2	ENTREZGENE
PANTHER	CRUMBS FAMILY MEMBER	UniProtKB/TrEMBL
	CYTOCHROME C OXIDASE POLYPEPTIDE VIC-2	UniProtKB/TrEMBL
	EGF-LIKE DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
	NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1	UniProtKB/TrEMBL
	NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1-RELATED	UniProtKB/TrEMBL
	PROTEIN CRUMBS HOMOLOG 1	UniProtKB/TrEMBL
	PROTEIN EYES SHUT	UniProtKB/TrEMBL
	PROTEIN SLIT	UniProtKB/TrEMBL
	SLIT HOMOLOG	UniProtKB/TrEMBL
Pfam	Ank	UniProtKB/TrEMBL
	Ank_2	UniProtKB/TrEMBL
	EGF	UniProtKB/TrEMBL
	EGF_CA	UniProtKB/TrEMBL
	hEGF	UniProtKB/TrEMBL
	NOD	UniProtKB/TrEMBL
	NODP	UniProtKB/TrEMBL
	Notch	UniProtKB/TrEMBL
PIRSF	Notch	UniProtKB/TrEMBL
PRINTS	EGFBLOOD	UniProtKB/TrEMBL
	LNOTCHREPEAT	UniProtKB/TrEMBL
	NOTCH	UniProtKB/TrEMBL
	NOTCH2	UniProtKB/TrEMBL
PROSITE	ANK_REP_REGION	UniProtKB/TrEMBL
	ANK_REPEAT	UniProtKB/TrEMBL
	ASX_HYDROXYL	UniProtKB/TrEMBL
	EGF_1	UniProtKB/TrEMBL
	EGF_2	UniProtKB/TrEMBL
	EGF_3	UniProtKB/TrEMBL
	EGF_CA	UniProtKB/TrEMBL
	LNR	UniProtKB/TrEMBL
SMART	ANK	UniProtKB/TrEMBL
	DUF3454	UniProtKB/TrEMBL
	EGF	UniProtKB/TrEMBL
	EGF_CA	UniProtKB/TrEMBL
	NOD	UniProtKB/TrEMBL
	NODP	UniProtKB/TrEMBL
	SM00004	UniProtKB/TrEMBL
Superfamily-SCOP	EGF/Laminin	UniProtKB/TrEMBL
	SSF48403	UniProtKB/TrEMBL
	SSF57184	UniProtKB/TrEMBL
	SSF90193	UniProtKB/TrEMBL
UniProt	A0A8C0SR20	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MX54_CANLF	UniProtKB/TrEMBL
	A0A8I3N2H2_CANLF	UniProtKB/TrEMBL
	A0A8I3N8F6_CANLF	UniProtKB/TrEMBL
	A0A8P0PHI1_CANLF	UniProtKB/TrEMBL
	A0A8P0SFF2_CANLF	UniProtKB/TrEMBL
	A0A8P0TMN2_CANLF	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-01-14	NOTCH2	notch receptor 2	LOC111090698	uncharacterized LOC111090698	Data merged from RGD:13231796	737654	PROVISIONAL
2019-01-08	NOTCH2	notch receptor 2		notch 2	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)