RAP2B (RAP2B, member of RAS oncogene family) - Rat Genome Database

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Gene: RAP2B (RAP2B, member of RAS oncogene family) Canis lupus familiaris
Analyze
Symbol: RAP2B
Name: RAP2B, member of RAS oncogene family
RGD ID: 12092316
Description: ENCODES a protein that exhibits GDP binding (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN establishment of endothelial intestinal barrier (ortholog); microvillus assembly (ortholog); negative regulation of cell migration (ortholog); FOUND IN bicellular tight junction (inferred); bounding membrane of organelle (inferred); cell-cell contact zone (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras-related protein Rap-2b
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12347,503,382 - 47,508,900 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2347,501,371 - 47,503,798 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2347,366,294 - 47,366,998 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02348,132,355 - 48,133,065 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2348,132,405 - 48,132,956 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12347,716,632 - 47,717,330 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02347,771,463 - 47,772,165 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02348,054,638 - 48,055,330 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RAP2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12347,503,382 - 47,508,900 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2347,501,371 - 47,503,798 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2347,366,294 - 47,366,998 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02348,132,355 - 48,133,065 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2348,132,405 - 48,132,956 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12347,716,632 - 47,717,330 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02347,771,463 - 47,772,165 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02348,054,638 - 48,055,330 (+)NCBIUU_Cfam_GSD_1.0
RAP2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383153,162,226 - 153,170,627 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3153,162,226 - 153,170,627 (+)EnsemblGRCh38hg38GRCh38
GRCh373152,880,015 - 152,888,416 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363154,362,719 - 154,368,955 (+)NCBINCBI36Build 36hg18NCBI36
Build 343154,362,726 - 154,368,959NCBI
Celera3151,298,062 - 151,304,298 (+)NCBICelera
Cytogenetic Map3q25.2NCBI
HuRef3150,272,070 - 150,280,482 (+)NCBIHuRef
CHM1_13152,843,496 - 152,851,905 (+)NCBICHM1_1
T2T-CHM13v2.03155,932,795 - 155,941,196 (+)NCBIT2T-CHM13v2.0
Rap2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39361,271,928 - 61,276,124 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl361,269,059 - 61,275,851 (+)EnsemblGRCm39 Ensembl
GRCm38361,364,507 - 61,368,703 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl361,361,638 - 61,368,430 (+)EnsemblGRCm38mm10GRCm38
MGSCv37361,168,429 - 61,172,625 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36361,452,523 - 61,456,367 (+)NCBIMGSCv36mm8
Celera361,050,530 - 61,054,794 (+)NCBICelera
Cytogenetic Map3E1NCBI
cM Map329.81NCBI
Rap2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82147,749,387 - 147,749,938 (+)NCBIGRCr8
mRatBN7.22145,599,714 - 145,600,265 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2145,599,116 - 145,603,069 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2152,271,935 - 152,272,486 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02150,374,642 - 150,375,193 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02145,007,038 - 145,007,589 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02151,685,251 - 151,685,802 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2151,685,251 - 151,685,802 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02171,097,071 - 171,097,622 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42150,826,483 - 150,827,034 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12150,776,445 - 150,776,997 (+)NCBI
Celera2139,989,922 - 139,990,473 (+)NCBICelera
Cytogenetic Map2q31NCBI
Rap2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554484,668,477 - 4,671,629 (+)NCBIChiLan1.0ChiLan1.0
RAP2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22151,055,932 - 151,058,669 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13151,060,882 - 151,070,886 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03150,188,107 - 150,193,060 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13157,754,307 - 157,760,249 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3157,754,470 - 157,755,021 (+)Ensemblpanpan1.1panPan2
Rap2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560288,611,521 - 88,618,087 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365191,116,009 - 1,116,560 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365191,115,865 - 1,121,196 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAP2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1393,308,112 - 93,308,663 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11393,308,112 - 93,308,663 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213101,331,694 - 101,346,671 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAP2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11537,502,236 - 37,505,829 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1537,504,830 - 37,505,378 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604110,224,854 - 10,229,493 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rap2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473030,788,414 - 30,788,965 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473030,788,382 - 30,790,402 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RAP2B
85 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000049624   ⟹   ENSCAFP00000038565
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2347,501,371 - 47,503,798 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845035255   ⟹   ENSCAFP00845027599
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2348,132,405 - 48,132,956 (+)Ensembl
RefSeq Acc Id: XM_038432719   ⟹   XP_038288647
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02348,132,355 - 48,133,065 (+)NCBI
RefSeq Acc Id: XM_038457190   ⟹   XP_038313118
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2347,366,294 - 47,366,998 (+)NCBI
RefSeq Acc Id: XM_038508018   ⟹   XP_038363946
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12347,716,632 - 47,717,330 (+)NCBI
RefSeq Acc Id: XM_038570198   ⟹   XP_038426126
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02348,054,638 - 48,055,330 (+)NCBI
RefSeq Acc Id: XM_038635454   ⟹   XP_038491382
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02347,771,463 - 47,772,165 (+)NCBI
Ensembl Acc Id: ENSCAFP00000038565   ⟸   ENSCAFT00000049624
RefSeq Acc Id: XP_038363946   ⟸   XM_038508018
RefSeq Acc Id: XP_038491382   ⟸   XM_038635454
RefSeq Acc Id: XP_038288647   ⟸   XM_038432719
- UniProtKB: A0A8C0JW15 (UniProtKB/TrEMBL),   A0A8C0SY13 (UniProtKB/TrEMBL),   A0A8I3PII6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038313118   ⟸   XM_038457190
- UniProtKB: A0A8C0JW15 (UniProtKB/TrEMBL),   A0A8C0SY13 (UniProtKB/TrEMBL),   A0A8I3PII6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038426126   ⟸   XM_038570198
- UniProtKB: A0A8C0JW15 (UniProtKB/TrEMBL),   A0A8C0SY13 (UniProtKB/TrEMBL),   A0A8I3PII6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845027599   ⟸   ENSCAFT00845035255


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000031794 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040017281 UniProtKB/TrEMBL
  ENSCAFG00845020015 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000049624.3 UniProtKB/TrEMBL
  ENSCAFT00040031928.1 UniProtKB/TrEMBL
  ENSCAFT00845035255 ENTREZGENE
  ENSCAFT00845035255.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Rap2 UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
  Small_GTPase_Ras-type UniProtKB/TrEMBL
NCBI Gene RAP2B ENTREZGENE
PANTHER PTHR24070 UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAP-2B UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8C0JW15 ENTREZGENE
  A0A8C0SY13 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PII6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:52900 ENTREZGENE