DCTPP1 (dCTP pyrophosphatase 1) - Rat Genome Database

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Gene: DCTPP1 (dCTP pyrophosphatase 1) Canis lupus familiaris
Analyze
Symbol: DCTPP1
Name: dCTP pyrophosphatase 1
RGD ID: 12091464
Description: ENCODES a protein that exhibits identical protein binding (ortholog); pyrimidine deoxyribonucleotide binding (ortholog); pyrophosphatase activity (ortholog); INVOLVED IN dTTP catabolic process (ortholog); ASSOCIATED WITH dilated cardiomyopathy (ortholog); FOUND IN mitochondrion (ortholog); nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1617,679,681 - 17,683,644 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl617,679,722 - 17,683,570 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,253,648 - 19,257,592 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0617,810,663 - 17,814,594 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl617,810,709 - 17,814,520 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1617,610,846 - 17,614,777 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0617,526,330 - 17,530,261 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0617,841,310 - 17,845,272 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (IBA,IEA)
mitochondrion  (ISO)
nucleoplasm  (ISO)
nucleus  (ISO)

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
DCTPP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1617,679,681 - 17,683,644 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl617,679,722 - 17,683,570 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,253,648 - 19,257,592 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0617,810,663 - 17,814,594 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl617,810,709 - 17,814,520 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1617,610,846 - 17,614,777 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0617,526,330 - 17,530,261 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0617,841,310 - 17,845,272 (+)NCBIUU_Cfam_GSD_1.0
DCTPP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381630,423,615 - 30,430,030 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1630,423,615 - 30,430,030 (-)EnsemblGRCh38hg38GRCh38
GRCh371630,434,936 - 30,441,351 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361630,342,520 - 30,348,874 (-)NCBINCBI36Build 36hg18NCBI36
Celera1629,857,548 - 29,863,885 (+)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1627,997,232 - 28,003,588 (-)NCBIHuRef
CHM1_11631,751,466 - 31,757,820 (-)NCBICHM1_1
T2T-CHM13v2.01630,809,819 - 30,816,234 (-)NCBIT2T-CHM13v2.0
Dctpp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397126,856,131 - 126,859,839 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7126,856,131 - 126,859,881 (-)EnsemblGRCm39 Ensembl
GRCm387127,256,959 - 127,260,667 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7127,256,959 - 127,260,709 (-)EnsemblGRCm38mm10GRCm38
MGSCv377134,400,473 - 134,404,181 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367127,048,107 - 127,051,815 (-)NCBIMGSCv36mm8
Celera7127,105,674 - 127,109,383 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.42NCBI
Dctpp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,307,933 - 191,311,326 (-)NCBIGRCr8
mRatBN7.21181,877,440 - 181,880,833 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,877,437 - 181,880,839 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1190,228,131 - 190,231,512 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01197,414,218 - 197,417,599 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01190,082,593 - 190,085,974 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01198,703,459 - 198,706,852 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,703,461 - 198,706,852 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01205,696,305 - 205,699,698 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,519,955 - 186,523,348 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11186,669,837 - 186,673,229 (-)NCBI
Celera1179,528,917 - 179,532,300 (-)NCBICelera
Cytogenetic Map1q37NCBI
Dctpp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554937,357,204 - 7,360,034 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554937,357,204 - 7,360,034 (-)NCBIChiLan1.0ChiLan1.0
DCTPP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21833,629,486 - 33,636,121 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11638,430,932 - 38,438,331 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01624,538,023 - 24,545,426 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11630,794,268 - 30,802,207 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1630,794,268 - 30,802,179 (-)Ensemblpanpan1.1panPan2
Dctpp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344124,782,876 - 124,786,371 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650112,879,241 - 12,884,287 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650112,880,745 - 12,884,240 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCTPP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl317,886,890 - 17,900,557 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1317,896,426 - 17,900,562 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2318,312,086 - 18,316,024 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DCTPP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1527,096,489 - 27,102,778 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl527,096,212 - 27,102,835 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660682,416,903 - 2,423,222 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in DCTPP1
29 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000026277   ⟹   ENSCAFP00000024404
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl617,679,722 - 17,683,570 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845025185   ⟹   ENSCAFP00845019805
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl617,810,709 - 17,814,520 (+)Ensembl
RefSeq Acc Id: XM_005621286   ⟹   XP_005621343
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1617,679,888 - 17,683,644 (+)NCBI
Dog10K_Boxer_Tasha619,253,870 - 19,257,592 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038478567   ⟹   XP_038334495
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1617,610,846 - 17,614,777 (+)NCBI
RefSeq Acc Id: XM_038478568   ⟹   XP_038334496
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1617,611,068 - 17,614,777 (+)NCBI
RefSeq Acc Id: XM_038539820   ⟹   XP_038395748
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0617,841,310 - 17,845,272 (+)NCBI
RefSeq Acc Id: XM_038539821   ⟹   XP_038395749
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0617,841,532 - 17,845,272 (+)NCBI
RefSeq Acc Id: XM_038603898   ⟹   XP_038459826
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0617,526,330 - 17,530,261 (+)NCBI
RefSeq Acc Id: XM_038603899   ⟹   XP_038459827
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0617,526,552 - 17,530,261 (+)NCBI
RefSeq Acc Id: XM_038668625   ⟹   XP_038524553
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0617,810,663 - 17,814,594 (+)NCBI
RefSeq Acc Id: XM_038668626   ⟹   XP_038524554
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0617,810,885 - 17,814,594 (+)NCBI
RefSeq Acc Id: XM_547022   ⟹   XP_547022
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1617,679,681 - 17,683,644 (+)NCBI
Dog10K_Boxer_Tasha619,253,648 - 19,257,592 (+)NCBI
Sequence:
RefSeq Acc Id: XP_547022   ⟸   XM_547022
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KV40 (UniProtKB/TrEMBL),   A0A8C0M3Y7 (UniProtKB/TrEMBL),   A0A8I3P1M0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005621343   ⟸   XM_005621286
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSCAFP00000024404   ⟸   ENSCAFT00000026277
RefSeq Acc Id: XP_038334495   ⟸   XM_038478567
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038334496   ⟸   XM_038478568
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038459826   ⟸   XM_038603898
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038459827   ⟸   XM_038603899
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038524553   ⟸   XM_038668625
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KV40 (UniProtKB/TrEMBL),   A0A8C0M3Y7 (UniProtKB/TrEMBL),   A0A8I3P1M0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038524554   ⟸   XM_038668626
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038395748   ⟸   XM_038539820
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KV40 (UniProtKB/TrEMBL),   A0A8C0M3Y7 (UniProtKB/TrEMBL),   A0A8I3P1M0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038395749   ⟸   XM_038539821
- Peptide Label: isoform X2
Ensembl Acc Id: ENSCAFP00845019805   ⟸   ENSCAFT00845025185


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000016594 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030002195 UniProtKB/TrEMBL
  ENSCAFG00040014280 UniProtKB/TrEMBL
  ENSCAFG00845014087 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000026277.3 UniProtKB/TrEMBL
  ENSCAFT00030004022.1 UniProtKB/TrEMBL
  ENSCAFT00040026334.1 UniProtKB/TrEMBL
  ENSCAFT00845025185 ENTREZGENE
  ENSCAFT00845025185.1 UniProtKB/TrEMBL
Gene3D-CATH MazG-like UniProtKB/TrEMBL
InterPro dCTP_Pyrophosphatase UniProtKB/TrEMBL
  DCTPP UniProtKB/TrEMBL
NCBI Gene DCTPP1 ENTREZGENE
PANTHER DCTP PYROPHOSPHATASE 1 UniProtKB/TrEMBL
  DCTP PYROPHOSPHATASE 1 UniProtKB/TrEMBL
Pfam MazG-like UniProtKB/TrEMBL
Superfamily-SCOP all-alpha NTP pyrophosphatases UniProtKB/TrEMBL
UniProt A0A8C0KV40 ENTREZGENE
  A0A8C0M3Y7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P1M0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:111430 ENTREZGENE