ENKD1 (enkurin domain containing 1) - Rat Genome Database

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Gene: ENKD1 (enkurin domain containing 1) Canis lupus familiaris
Analyze
Symbol: ENKD1
Name: enkurin domain containing 1
RGD ID: 12090798
Description: ENCODES a protein that exhibits alpha-tubulin binding (ortholog); microtubule binding (ortholog); INVOLVED IN establishment of mitotic spindle orientation (ortholog); motile cilium assembly (ortholog); non-motile cilium assembly (ortholog); ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); chromosome 16q22 deletion syndrome (ortholog); genetic disease (ortholog); FOUND IN 9+0 non-motile cilium (ortholog); centriole (ortholog); centrosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: enkurin domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1581,783,887 - 81,787,244 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl581,784,109 - 81,787,243 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha581,773,605 - 81,777,006 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0582,219,011 - 82,222,412 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl582,219,276 - 82,222,411 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1582,045,340 - 82,048,741 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0581,726,875 - 81,730,276 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0582,369,424 - 82,372,825 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ENKD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1581,783,887 - 81,787,244 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl581,784,109 - 81,787,243 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha581,773,605 - 81,777,006 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0582,219,011 - 82,222,412 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl582,219,276 - 82,222,411 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1582,045,340 - 82,048,741 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0581,726,875 - 81,730,276 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0582,369,424 - 82,372,825 (+)NCBIUU_Cfam_GSD_1.0
ENKD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381667,662,945 - 67,666,750 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1667,662,945 - 67,667,265 (-)EnsemblGRCh38hg38GRCh38
GRCh371667,696,848 - 67,700,653 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361666,254,351 - 66,258,129 (-)NCBINCBI36Build 36hg18NCBI36
Build 341666,254,350 - 66,258,129NCBI
Celera1652,205,340 - 52,209,118 (-)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1653,569,762 - 53,573,539 (-)NCBIHuRef
CHM1_11669,104,563 - 69,108,341 (-)NCBICHM1_1
T2T-CHM13v2.01673,457,713 - 73,461,518 (-)NCBIT2T-CHM13v2.0
Enkd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398106,430,281 - 106,435,358 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8106,430,283 - 106,434,842 (-)EnsemblGRCm39 Ensembl
GRCm388105,703,649 - 105,708,221 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8105,703,651 - 105,708,210 (-)EnsemblGRCm38mm10GRCm38
MGSCv378108,227,552 - 108,232,068 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368108,592,781 - 108,597,299 (-)NCBIMGSCv36mm8
Celera8109,928,570 - 109,933,086 (-)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.04NCBI
Enkd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81950,501,963 - 50,506,447 (-)NCBIGRCr8
mRatBN7.21933,592,074 - 33,596,552 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1933,592,078 - 33,596,545 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1940,407,645 - 40,412,098 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01941,060,977 - 41,065,430 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01943,358,750 - 43,363,234 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01937,670,624 - 37,675,101 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,670,624 - 37,675,077 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01948,537,328 - 48,541,817 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41935,535,886 - 35,540,340 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11935,540,768 - 35,545,188 (-)NCBI
Celera1933,020,021 - 33,024,474 (-)NCBICelera
Cytogenetic Map19q12NCBI
Enkd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554849,016,049 - 9,019,568 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554849,015,744 - 9,019,781 (+)NCBIChiLan1.0ChiLan1.0
ENKD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21877,191,123 - 77,194,689 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11683,103,588 - 83,107,151 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01648,006,827 - 48,010,646 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11667,396,162 - 67,399,988 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1667,396,162 - 67,399,956 (-)Ensemblpanpan1.1panPan2
Enkd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934941,530,153 - 41,534,107 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647518,054,983 - 18,058,633 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647518,055,005 - 18,058,925 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ENKD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl628,283,117 - 28,287,306 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1628,283,108 - 28,289,266 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ENKD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1559,777,714 - 59,781,715 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl559,777,748 - 59,781,499 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604722,531,440 - 22,535,469 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Enkd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474618,682,597 - 18,686,735 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474618,676,146 - 18,686,739 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ENKD1
29 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 1 6 1 1
Low 5 5 18 3 5 3 6 5 12 2 9 5
Below cutoff 3 3 3 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000032409   ⟹   ENSCAFP00000030179
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl581,784,109 - 81,787,243 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845012167   ⟹   ENSCAFP00845009508
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl582,219,276 - 82,222,411 (+)Ensembl
RefSeq Acc Id: XM_003639073   ⟹   XP_003639121
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1581,783,887 - 81,787,244 (+)NCBI
Dog10K_Boxer_Tasha581,773,605 - 81,777,006 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038477397   ⟹   XP_038333325
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1582,045,340 - 82,048,741 (+)NCBI
RefSeq Acc Id: XM_038538605   ⟹   XP_038394533
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0582,369,424 - 82,372,825 (+)NCBI
RefSeq Acc Id: XM_038602719   ⟹   XP_038458647
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0581,726,875 - 81,730,276 (+)NCBI
RefSeq Acc Id: XM_038667328   ⟹   XP_038523256
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0582,219,011 - 82,222,412 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003639121   ⟸   XM_003639073
- UniProtKB: A0A8C0NUA9 (UniProtKB/TrEMBL),   A0A8I3MZ13 (UniProtKB/TrEMBL),   A0A8C0KXL7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000030179   ⟸   ENSCAFT00000032409
RefSeq Acc Id: XP_038333325   ⟸   XM_038477397
RefSeq Acc Id: XP_038458647   ⟸   XM_038602719
RefSeq Acc Id: XP_038523256   ⟸   XM_038667328
- UniProtKB: A0A8C0NUA9 (UniProtKB/TrEMBL),   A0A8I3MZ13 (UniProtKB/TrEMBL),   A0A8C0KXL7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038394533   ⟸   XM_038538605
- UniProtKB: A0A8C0KXL7 (UniProtKB/TrEMBL),   A0A8C0NUA9 (UniProtKB/TrEMBL),   A0A8I3MZ13 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845009508   ⟸   ENSCAFT00845012167
Protein Domains
Enkurin

Promoters
RGD ID:13683475
Promoter ID:EPDNEW_C1541
Type:single initiation site
Name:ENKD1_1
Description:enkurin domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1581,784,178 - 81,784,238EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000020350 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030018829 UniProtKB/TrEMBL
  ENSCAFG00040015431 UniProtKB/TrEMBL
  ENSCAFG00845006848 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000032409.5 UniProtKB/TrEMBL
  ENSCAFT00030034710.1 UniProtKB/TrEMBL
  ENSCAFT00040028485.1 UniProtKB/TrEMBL
  ENSCAFT00845012167 ENTREZGENE
  ENSCAFT00845012167.1 UniProtKB/TrEMBL
InterPro Enkurin_dom UniProtKB/TrEMBL
KEGG Report cfa:100855812 UniProtKB/TrEMBL
NCBI Gene ENKD1 ENTREZGENE
PANTHER PTHR21490:SF2 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam Enkurin UniProtKB/TrEMBL
PROSITE ENKURIN UniProtKB/TrEMBL
UniProt A0A8C0KXL7 ENTREZGENE
  A0A8C0NUA9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MZ13 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:40364 ENTREZGENE