CFD (complement factor D) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: CFD (complement factor D) Canis lupus familiaris
Analyze
Symbol: CFD
Name: complement factor D
RGD ID: 12088608
Description: ENCODES a protein that exhibits endopeptidase activity (ortholog); INVOLVED IN complement activation, alternative pathway (ortholog); Notch signaling pathway (ortholog); response to bacterium (ortholog); ASSOCIATED WITH arthus reaction (ortholog); asbestosis (ortholog); cerebral creatine deficiency syndrome (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,785,297 - 57,787,773 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2057,657,154 - 57,787,713 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,587,313 - 57,589,790 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02058,527,568 - 58,530,058 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,527,625 - 58,529,997 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,582,382 - 57,584,835 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02058,062,090 - 58,064,488 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02058,265,041 - 58,267,518 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
CFD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,785,297 - 57,787,773 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2057,657,154 - 57,787,713 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,587,313 - 57,589,790 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02058,527,568 - 58,530,058 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,527,625 - 58,529,997 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,582,382 - 57,584,835 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02058,062,090 - 58,064,488 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02058,265,041 - 58,267,518 (-)NCBIUU_Cfam_GSD_1.0
CFD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3819859,664 - 863,641 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl19859,453 - 867,884 (+)EnsemblGRCh38hg38GRCh38
GRCh3719859,664 - 863,641 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3619810,665 - 814,624 (+)NCBINCBI36Build 36hg18NCBI36
Build 3419810,664 - 814,608NCBI
Celera19784,591 - 789,264 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef19628,736 - 632,629 (+)NCBIHuRef
CHM1_119859,248 - 863,166 (+)NCBICHM1_1
T2T-CHM13v2.019815,769 - 819,749 (+)NCBIT2T-CHM13v2.0
Cfd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391079,726,687 - 79,728,489 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1079,726,687 - 79,728,489 (+)EnsemblGRCm39 Ensembl
GRCm381079,890,853 - 79,892,655 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1079,890,853 - 79,892,655 (+)EnsemblGRCm38mm10GRCm38
MGSCv371079,353,598 - 79,355,401 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361079,294,041 - 79,295,783 (+)NCBIMGSCv36mm8
Celera1080,905,663 - 80,907,466 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Cfd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.279,813,148 - 9,814,871 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,813,150 - 9,815,053 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,695,134 - 12,696,857 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0714,570,451 - 14,572,174 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0712,431,649 - 12,433,373 (-)NCBIRnor_WKY
Rnor_6.0712,634,216 - 12,635,939 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,634,216 - 12,635,943 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,803,938 - 12,805,661 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4711,325,538 - 11,327,261 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1711,325,546 - 11,327,251 (-)NCBI
Celera77,987,896 - 7,989,620 (-)NCBICelera
RH 3.4 Map741.1RGD
Cytogenetic Map7q11NCBI
Cfd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554956,955,612 - 6,961,317 (-)NCBIChiLan1.0ChiLan1.0
Cfd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118217,482,051 - 217,483,972 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936588350,925 - 352,732 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CFD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl277,509,795 - 77,511,974 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1277,509,792 - 77,511,988 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2277,485,653 - 77,487,849 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CFD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.16608,821 - 612,382 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl6608,800 - 613,498 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660818,304,252 - 8,308,149 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cfd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248287,711,537 - 7,717,337 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248287,714,926 - 7,717,139 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000036204   ⟹   ENSCAFP00000031556
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2057,657,154 - 57,667,306 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000046170   ⟹   ENSCAFP00000040877
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2057,785,366 - 57,787,713 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000092467   ⟹   ENSCAFP00000059890
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2057,662,643 - 57,787,163 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845025968   ⟹   ENSCAFP00845020471
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2058,527,625 - 58,529,447 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845025980   ⟹   ENSCAFP00845020481
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2058,527,625 - 58,529,447 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845025998   ⟹   ENSCAFP00845020496
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2058,527,637 - 58,529,997 (-)Ensembl
RefSeq Acc Id: XM_014122378   ⟹   XP_013977853
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12057,785,297 - 57,787,773 (-)NCBI
Dog10K_Boxer_Tasha2057,587,313 - 57,589,790 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038429363   ⟹   XP_038285291
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02058,527,568 - 58,530,058 (-)NCBI
RefSeq Acc Id: XM_038429364   ⟹   XP_038285292
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02058,527,568 - 58,530,058 (-)NCBI
RefSeq Acc Id: XM_038504888   ⟹   XP_038360816
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12057,582,382 - 57,584,835 (-)NCBI
RefSeq Acc Id: XM_038504889   ⟹   XP_038360817
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12057,582,382 - 57,584,835 (-)NCBI
RefSeq Acc Id: XM_038568046   ⟹   XP_038423974
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02058,265,041 - 58,267,518 (-)NCBI
RefSeq Acc Id: XM_038568047   ⟹   XP_038423975
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02058,265,041 - 58,267,518 (-)NCBI
RefSeq Acc Id: XM_038632155   ⟹   XP_038488083
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02058,062,090 - 58,064,488 (-)NCBI
RefSeq Acc Id: XM_038632156   ⟹   XP_038488084
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02058,062,090 - 58,064,488 (-)NCBI
RefSeq Acc Id: XM_542213   ⟹   XP_542213
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12057,785,297 - 57,787,773 (-)NCBI
Dog10K_Boxer_Tasha2057,587,313 - 57,589,790 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_013977853   ⟸   XM_014122378
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_542213   ⟸   XM_542213
- Peptide Label: isoform X2
- UniProtKB: J9P5F0 (UniProtKB/TrEMBL),   A0A8C0KZD4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000059890   ⟸   ENSCAFT00000092467
RefSeq Acc Id: ENSCAFP00000031556   ⟸   ENSCAFT00000036204
RefSeq Acc Id: ENSCAFP00000040877   ⟸   ENSCAFT00000046170
RefSeq Acc Id: XP_038360817   ⟸   XM_038504889
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038360816   ⟸   XM_038504888
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038488084   ⟸   XM_038632156
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038488083   ⟸   XM_038632155
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038285292   ⟸   XM_038429364
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KZD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038285291   ⟸   XM_038429363
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038423975   ⟸   XM_038568047
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038423974   ⟸   XM_038568046
- Peptide Label: isoform X1
RefSeq Acc Id: ENSCAFP00845020471   ⟸   ENSCAFT00845025968
RefSeq Acc Id: ENSCAFP00845020496   ⟸   ENSCAFT00845025998
RefSeq Acc Id: ENSCAFP00845020481   ⟸   ENSCAFT00845025980
Protein Domains
Peptidase S1

Promoters
RGD ID:13687137
Promoter ID:EPDNEW_C5205
Type:multiple initiation site
Name:CFD_1
Description:complement factor D
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12057,787,040 - 57,787,100EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000019552 Ensembl
  ENSCAFG00845014517 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00845020471 ENTREZGENE
  ENSCAFP00845020471.1 UniProtKB/TrEMBL
  ENSCAFP00845020481.1 UniProtKB/TrEMBL
  ENSCAFP00845020496 ENTREZGENE
  ENSCAFP00845020496.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00845025968 ENTREZGENE
  ENSCAFT00845025968.1 UniProtKB/TrEMBL
  ENSCAFT00845025980.1 UniProtKB/TrEMBL
  ENSCAFT00845025998 ENTREZGENE
  ENSCAFT00845025998.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
InterPro Complement_factor_D UniProtKB/TrEMBL
  Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
NCBI Gene CFD ENTREZGENE
PANTHER PTHR24271:SF54 UniProtKB/TrEMBL
Pfam Trypsin UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
SMART Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
UniProt A0A8C0KZD4 ENTREZGENE
  A0A8I3NIC8_CANLF UniProtKB/TrEMBL
  A0A8I3NTV7_CANLF UniProtKB/TrEMBL
  A0A8I3RY54_CANLF UniProtKB/TrEMBL
  J9P5F0 ENTREZGENE
VGNC ID VGNC:39174 ENTREZGENE