TRIM62 (tripartite motif containing 62) - Rat Genome Database

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Gene: TRIM62 (tripartite motif containing 62) Canis lupus familiaris
Analyze
Symbol: TRIM62
Name: tripartite motif containing 62
RGD ID: 12086987
Description: ENCODES a protein that exhibits identical protein binding (inferred); metal ion binding (inferred); transcription coactivator activity (inferred); INVOLVED IN negative regulation of epithelial to mesenchymal transition (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase TRIM62; tripartite motif-containing protein 62
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1268,247,138 - 68,265,530 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl268,247,139 - 68,264,754 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha264,814,365 - 64,845,785 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0268,798,384 - 68,829,793 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl268,798,365 - 68,829,788 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1265,611,056 - 65,642,474 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0266,633,570 - 66,665,005 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0267,625,508 - 67,656,947 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TRIM62
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1268,247,138 - 68,265,530 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl268,247,139 - 68,264,754 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha264,814,365 - 64,845,785 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0268,798,384 - 68,829,793 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl268,798,365 - 68,829,788 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1265,611,056 - 65,642,474 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0266,633,570 - 66,665,005 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0267,625,508 - 67,656,947 (+)NCBIUU_Cfam_GSD_1.0
TRIM62
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38133,145,399 - 33,182,043 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl133,145,399 - 33,182,059 (-)EnsemblGRCh38hg38GRCh38
GRCh37133,611,000 - 33,647,644 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36133,383,591 - 33,419,854 (-)NCBINCBI36Build 36hg18NCBI36
Build 34133,280,096 - 33,316,360NCBI
Celera131,881,193 - 31,917,797 (-)NCBICelera
Cytogenetic Map1p35.1NCBI
HuRef131,726,962 - 31,763,317 (-)NCBIHuRef
CHM1_1133,726,505 - 33,763,168 (-)NCBICHM1_1
T2T-CHM13v2.0133,005,274 - 33,041,915 (-)NCBIT2T-CHM13v2.0
Trim62
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394128,777,837 - 128,805,119 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4128,777,373 - 128,805,121 (+)EnsemblGRCm39 Ensembl
GRCm384128,884,044 - 128,911,326 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4128,883,580 - 128,911,328 (+)EnsemblGRCm38mm10GRCm38
MGSCv374128,561,384 - 128,588,570 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364128,386,444 - 128,413,630 (+)NCBIMGSCv36mm8
Celera4127,221,836 - 127,249,023 (+)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map462.38NCBI
Trim62
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85146,516,349 - 146,545,015 (+)NCBIGRCr8
mRatBN7.25141,230,830 - 141,260,629 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5141,231,523 - 141,259,915 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.05147,068,725 - 147,099,024 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5147,069,616 - 147,095,242 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05150,799,760 - 150,830,499 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5139,714,974 - 139,746,021 (+)NCBICelera
Cytogenetic Map5q36NCBI
Trim62
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545211,347,741 - 11,378,040 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545211,348,001 - 11,377,413 (-)NCBIChiLan1.0ChiLan1.0
TRIM62
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21193,645,961 - 193,683,002 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11192,768,060 - 192,805,170 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0132,429,824 - 32,467,185 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1133,614,555 - 33,650,859 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl133,614,555 - 33,650,859 (-)Ensemblpanpan1.1panPan2
Trim62
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505850,174,190 - 50,204,740 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647415,998,973 - 16,029,599 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647415,998,996 - 16,029,555 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM62
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl689,406,478 - 89,442,746 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1689,406,470 - 89,442,794 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2683,434,103 - 83,470,360 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRIM62
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12099,697,568 - 99,731,660 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2099,698,497 - 99,731,379 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603316,958,127 - 16,993,441 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trim62
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476416,200,539 - 16,230,780 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476416,200,539 - 16,230,713 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TRIM62
250 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 1
Low 5 5 21 6 6 6 6 12 8 9 6
Below cutoff 6

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005617610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038461639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038461640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038470325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038470326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038531167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038531168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038595388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038595389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038659470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038659471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000050202   ⟹   ENSCAFP00000037927
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl268,247,139 - 68,264,754 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845009049   ⟹   ENSCAFP00845007135
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl268,798,365 - 68,829,788 (+)Ensembl
RefSeq Acc Id: XM_038461639   ⟹   XP_038317567
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha264,814,365 - 64,845,785 (+)NCBI
RefSeq Acc Id: XM_038461640   ⟹   XP_038317568
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha264,814,367 - 64,845,785 (+)NCBI
RefSeq Acc Id: XM_038470325   ⟹   XP_038326253
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1265,611,056 - 65,642,474 (+)NCBI
RefSeq Acc Id: XM_038470326   ⟹   XP_038326254
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1265,611,058 - 65,642,474 (+)NCBI
RefSeq Acc Id: XM_038531167   ⟹   XP_038387095
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0267,625,508 - 67,656,947 (+)NCBI
RefSeq Acc Id: XM_038531168   ⟹   XP_038387096
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0267,625,510 - 67,656,947 (+)NCBI
RefSeq Acc Id: XM_038595388   ⟹   XP_038451316
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0266,633,570 - 66,665,005 (+)NCBI
RefSeq Acc Id: XM_038595389   ⟹   XP_038451317
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0266,633,572 - 66,665,005 (+)NCBI
RefSeq Acc Id: XM_038659470   ⟹   XP_038515398
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0268,798,384 - 68,829,793 (+)NCBI
RefSeq Acc Id: XM_038659471   ⟹   XP_038515399
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0268,798,386 - 68,829,793 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000037927   ⟸   ENSCAFT00000050202
RefSeq Acc Id: XP_038326253   ⟸   XM_038470325
RefSeq Acc Id: XP_038326254   ⟸   XM_038470326
RefSeq Acc Id: XP_038451316   ⟸   XM_038595388
RefSeq Acc Id: XP_038451317   ⟸   XM_038595389
RefSeq Acc Id: XP_038515398   ⟸   XM_038659470
- UniProtKB: A0A8C0T736 (UniProtKB/TrEMBL),   A0A8I3MZ68 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038515399   ⟸   XM_038659471
- UniProtKB: A0A8C0T736 (UniProtKB/TrEMBL),   A0A8I3MZ68 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038317567   ⟸   XM_038461639
- UniProtKB: A0A8C0T736 (UniProtKB/TrEMBL),   A0A8I3MZ68 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038317568   ⟸   XM_038461640
- UniProtKB: A0A8C0T736 (UniProtKB/TrEMBL),   A0A8I3MZ68 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038387095   ⟸   XM_038531167
- UniProtKB: A0A8C0T736 (UniProtKB/TrEMBL),   A0A8I3MZ68 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038387096   ⟸   XM_038531168
- UniProtKB: A0A8C0T736 (UniProtKB/TrEMBL),   A0A8I3MZ68 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845007135   ⟸   ENSCAFT00845009049
Protein Domains
B box-type   B30.2/SPRY   RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000029972 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030014551 UniProtKB/TrEMBL
  ENSCAFG00040019614 UniProtKB/TrEMBL
  ENSCAFG00845005051 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000050202.3 UniProtKB/TrEMBL
  ENSCAFT00030026866.1 UniProtKB/TrEMBL
  ENSCAFT00040036278.1 UniProtKB/TrEMBL
  ENSCAFT00845009049 ENTREZGENE
  ENSCAFT00845009049.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/TrEMBL
  Butyrophylin_SPRY UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
  PRY UniProtKB/TrEMBL
  PRY/SPRY_TRIM62 UniProtKB/TrEMBL
  SPRY_dom UniProtKB/TrEMBL
  Znf_B-box UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
NCBI Gene TRIM62 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE TRIM UniProtKB/TrEMBL
  E3 UBIQUITIN-PROTEIN LIGASE TRIM62 UniProtKB/TrEMBL
Pfam PRY UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
  zf-B_box UniProtKB/TrEMBL
  zf-C3HC4_4 UniProtKB/TrEMBL
PRINTS BUTYPHLNCDUF UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/TrEMBL
  ZF_BBOX UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART PRY UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP B-box zinc-binding domain UniProtKB/TrEMBL
  RING/U-box UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
UniProt A0A8C0T736 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MZ68 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:47830 ENTREZGENE