CCDC174 (coiled-coil domain containing 174) - Rat Genome Database

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Gene: CCDC174 (coiled-coil domain containing 174) Canis lupus familiaris
Analyze
Symbol: CCDC174
Name: coiled-coil domain containing 174
RGD ID: 12085037
Description: ASSOCIATED WITH 3p deletion syndrome (ortholog); genetic disease (ortholog); Infantile Hypotonia with Psychomotor Retardation (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: C20H3orf19; coiled-coil domain-containing protein 174
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1204,753,433 - 4,778,446 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl204,753,542 - 4,776,032 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha204,790,684 - 4,815,700 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0204,774,753 - 4,799,759 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl204,774,805 - 4,800,473 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1204,493,265 - 4,518,281 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0204,815,868 - 4,840,874 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0204,827,384 - 4,852,402 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CCDC174
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1204,753,433 - 4,778,446 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl204,753,542 - 4,776,032 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha204,790,684 - 4,815,700 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0204,774,753 - 4,799,759 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl204,774,805 - 4,800,473 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1204,493,265 - 4,518,281 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0204,815,868 - 4,840,874 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0204,827,384 - 4,852,402 (+)NCBIUU_Cfam_GSD_1.0
CCDC174
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38314,651,762 - 14,672,655 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl314,651,762 - 14,672,659 (+)EnsemblGRCh38hg38GRCh38
GRCh37314,693,269 - 14,714,162 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36314,668,257 - 14,689,170 (+)NCBINCBI36Build 36hg18NCBI36
Build 34314,668,272 - 14,689,164NCBI
Celera314,631,500 - 14,652,414 (+)NCBICelera
Cytogenetic Map3p25.1NCBI
HuRef314,629,033 - 14,649,937 (+)NCBIHuRef
CHM1_1314,644,329 - 14,665,233 (+)NCBICHM1_1
T2T-CHM13v2.0314,654,184 - 14,675,068 (+)NCBIT2T-CHM13v2.0
Ccdc174
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39691,819,983 - 91,876,830 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl691,855,034 - 91,876,824 (+)EnsemblGRCm39 Ensembl
GRCm38691,843,154 - 91,899,849 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl691,878,053 - 91,899,843 (+)EnsemblGRCm38mm10GRCm38
MGSCv37691,828,047 - 91,849,842 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36691,843,576 - 91,865,352 (+)NCBIMGSCv36mm8
Celera693,772,237 - 93,794,129 (+)NCBICelera
Cytogenetic Map6D1NCBI
cM Map640.9NCBI
Ccdc174
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84125,949,203 - 125,976,179 (+)NCBIGRCr8
mRatBN7.24124,392,183 - 124,419,035 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4124,392,274 - 124,419,035 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4129,859,277 - 129,885,975 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04125,633,713 - 125,660,411 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04124,258,252 - 124,284,946 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04123,760,708 - 123,787,529 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4123,760,743 - 123,787,528 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04189,474,030 - 189,501,580 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44126,074,136 - 126,100,614 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14126,318,976 - 126,345,455 (+)NCBI
Celera4113,310,952 - 113,336,955 (+)NCBICelera
Cytogenetic Map4q34NCBI
Ccdc174
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542917,201,027 - 17,218,726 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542917,201,563 - 17,218,726 (+)NCBIChiLan1.0ChiLan1.0
CCDC174
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2214,629,283 - 14,653,081 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1314,638,091 - 14,657,844 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0314,574,082 - 14,595,025 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1314,913,345 - 14,934,261 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl314,913,328 - 14,934,261 (+)Ensemblpanpan1.1panPan2
Ccdc174
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494218,534,700 - 18,549,164 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936602360,604 - 374,952 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936602360,048 - 374,960 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCDC174
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1369,895,325 - 69,915,655 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11369,898,803 - 69,918,896 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CCDC174
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12250,595,136 - 50,616,165 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2250,595,175 - 50,614,691 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041115,876,965 - 115,899,803 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccdc174
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248721,176,568 - 1,193,192 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248721,176,317 - 1,193,344 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CCDC174
125 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 11 4 3 8 6 10 1
Low 5 5 11 6 2 6 3 6 4 2 5
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000007247   ⟹   ENSCAFP00000006712
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl204,753,542 - 4,776,032 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000066226   ⟹   ENSCAFP00000057578
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl204,753,542 - 4,776,032 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845044709   ⟹   ENSCAFP00845035031
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl204,774,805 - 4,800,473 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845044786   ⟹   ENSCAFP00845035097
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl204,774,805 - 4,800,473 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845044839   ⟹   ENSCAFP00845035139
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl204,774,805 - 4,780,736 (+)Ensembl
RefSeq Acc Id: XM_005632114   ⟹   XP_005632171
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1204,753,433 - 4,778,446 (+)NCBI
Dog10K_Boxer_Tasha204,790,684 - 4,815,700 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005632115   ⟹   XP_005632172
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1204,753,433 - 4,778,446 (+)NCBI
Dog10K_Boxer_Tasha204,790,684 - 4,815,700 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038426850   ⟹   XP_038282778
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0204,774,753 - 4,799,759 (+)NCBI
RefSeq Acc Id: XM_038426851   ⟹   XP_038282779
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0204,774,753 - 4,799,759 (+)NCBI
RefSeq Acc Id: XM_038502646   ⟹   XP_038358574
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1204,493,265 - 4,518,281 (+)NCBI
RefSeq Acc Id: XM_038502647   ⟹   XP_038358575
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1204,493,265 - 4,518,281 (+)NCBI
RefSeq Acc Id: XM_038565559   ⟹   XP_038421487
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0204,827,384 - 4,852,402 (+)NCBI
RefSeq Acc Id: XM_038565560   ⟹   XP_038421488
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0204,827,384 - 4,852,402 (+)NCBI
RefSeq Acc Id: XM_038629695   ⟹   XP_038485623
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0204,815,868 - 4,840,874 (+)NCBI
RefSeq Acc Id: XM_038629696   ⟹   XP_038485624
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0204,815,868 - 4,840,874 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005632171   ⟸   XM_005632114
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NXU0 (UniProtKB/TrEMBL),   A0A8I3S586 (UniProtKB/TrEMBL),   A0A8C0T3M4 (UniProtKB/TrEMBL),   A0A8I3PUJ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005632172   ⟸   XM_005632115
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JZQ2 (UniProtKB/TrEMBL),   A0A8C0T3M4 (UniProtKB/TrEMBL),   A0A8I3PUJ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000057578   ⟸   ENSCAFT00000066226
RefSeq Acc Id: ENSCAFP00000006712   ⟸   ENSCAFT00000007247
RefSeq Acc Id: XP_038358574   ⟸   XM_038502646
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038358575   ⟸   XM_038502647
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038485623   ⟸   XM_038629695
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038485624   ⟸   XM_038629696
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038282778   ⟸   XM_038426850
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NXU0 (UniProtKB/TrEMBL),   A0A8I3S586 (UniProtKB/TrEMBL),   A0A8C0T3M4 (UniProtKB/TrEMBL),   A0A8I3PUJ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038282779   ⟸   XM_038426851
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JZQ2 (UniProtKB/TrEMBL),   A0A8C0T3M4 (UniProtKB/TrEMBL),   A0A8I3PUJ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038421487   ⟸   XM_038565559
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NXU0 (UniProtKB/TrEMBL),   A0A8C0T3M4 (UniProtKB/TrEMBL),   A0A8I3PUJ0 (UniProtKB/TrEMBL),   A0A8I3S586 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038421488   ⟸   XM_038565560
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JZQ2 (UniProtKB/TrEMBL),   A0A8C0T3M4 (UniProtKB/TrEMBL),   A0A8I3PUJ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845035031   ⟸   ENSCAFT00845044709
RefSeq Acc Id: ENSCAFP00845035139   ⟸   ENSCAFT00845044839
RefSeq Acc Id: ENSCAFP00845035097   ⟸   ENSCAFT00845044786

Promoters
RGD ID:13686764
Promoter ID:EPDNEW_C4833
Type:initiation region
Name:CCDC174_1
Description:coiled-coil domain containing 174
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1204,753,501 - 4,753,561EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000004495 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030018780 UniProtKB/TrEMBL
  ENSCAFG00040018368 UniProtKB/TrEMBL
  ENSCAFG00845025324 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000007247.5 UniProtKB/TrEMBL
  ENSCAFT00030034794.1 UniProtKB/TrEMBL
  ENSCAFT00030034870.1 UniProtKB/TrEMBL
  ENSCAFT00040034151.1 UniProtKB/TrEMBL
  ENSCAFT00040034224.1 UniProtKB/TrEMBL
  ENSCAFT00845044709 ENTREZGENE
  ENSCAFT00845044709.1 UniProtKB/TrEMBL
  ENSCAFT00845044786.1 UniProtKB/TrEMBL
  ENSCAFT00845044839.1 UniProtKB/TrEMBL
InterPro DUF4078 UniProtKB/TrEMBL
KEGG Report cfa:100686384 UniProtKB/TrEMBL
NCBI Gene CCDC174 ENTREZGENE
PANTHER COILED-COIL DOMAIN-CONTAINING PROTEIN 174 UniProtKB/TrEMBL
  PTHR15885 UniProtKB/TrEMBL
Pfam DUF4078 UniProtKB/TrEMBL
UniProt A0A8C0JZQ2 ENTREZGENE
  A0A8C0NXU0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0T3M4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PUJ0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S586 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S5A4_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:38813 ENTREZGENE