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Gene: MYO5B (myosin VB) Canis lupus familiaris

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Symbol:

MYO5B

Name:

myosin VB

RGD ID:

12084616

Description:

ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); ionotropic glutamate receptor binding (ortholog); small GTPase binding (ortholog); INVOLVED IN cellular response to glycine (ortholog); dendritic spine morphogenesis (ortholog); modulation of chemical synaptic transmission (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; vasopressin signaling pathway; vasopressin signaling pathway via receptor type 2; ASSOCIATED WITH amphetamine abuse (ortholog); Crohn's disease (ortholog); diarrhea (ortholog); FOUND IN brush border (ortholog); dendritic spine (ortholog); glutamatergic synapse (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

myosin-Vb; unconventional myosin-Vb

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MYO5B (myosin VB)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Treefam
Mus musculus (house mouse):	Myo5b (myosin VB)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Myo5b (myosin Vb)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Myo5b (myosin VB)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MYO5B (myosin VB)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Myo5b (myosin VB)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MYO5B (myosin VB)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MYO5B (myosin VB)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Myo5b (myosin VB)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	78,671,636 - 79,006,010 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	78,671,616 - 79,006,006 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	78,076,067 - 78,407,834 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	78,734,540 - 79,067,184 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	78,734,614 - 79,067,103 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	78,448,208 - 78,782,608 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	78,479,066 - 78,811,670 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	78,763,776 - 79,096,706 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amphetamine abuse (ISO)

Crohn's disease (ISO)

diarrhea (ISO)

genetic disease (ISO)

inflammatory bowel disease 1 (ISO)

inherited metabolic disorder (ISO)

intellectual disability (ISO)

intestinal disease (ISO)

Liver Neoplasms (ISO)

microvillus inclusion disease (ISO)

Progressive Familial Intrahepatic Cholestasis 10 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to glycine (ISO)

dendritic spine morphogenesis (ISO)

endosomal transport (IEA)

modulation of chemical synaptic transmission (ISO)

neurotransmitter receptor transport, endosome to plasma membrane (ISO)

positive regulation of axon extension (ISO)

positive regulation of dendrite morphogenesis (ISO)

positive regulation of exosomal secretion (ISO)

positive regulation of protein localization to plasma membrane (ISO)

protein transmembrane transport (ISO)

regulation of modification of postsynaptic structure (ISO)

regulation of protein localization (ISO)

synaptic vesicle recycling via endosome (ISO)

vesicle-mediated transport (IEA)

vesicle-mediated transport in synapse (ISO)

Cellular Component

apical cortex (IEA)

brush border (ISO)

dendritic spine (ISO)

glutamatergic synapse (ISO)

myosin complex (IEA)

neuronal cell body (ISO)

perinuclear region of cytoplasm (ISO)

postsynapse (ISO)

postsynaptic actin cytoskeleton (ISO)

postsynaptic recycling endosome membrane (ISO)

protein-containing complex (IEA)

recycling endosome (ISO)

Schaffer collateral - CA1 synapse (ISO)

Molecular Function

actin binding (IEA)

ATP binding (IEA)

ATP hydrolysis activity (ISO)

cytoskeletal motor activity (IEA)

ionotropic glutamate receptor binding (ISO)

protein binding (ISO)

small GTPase binding (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

insulin responsive facilitative sugar transporter mediated glucose transport pathway (ISO)

vasopressin signaling pathway (ISO)

vasopressin signaling pathway via receptor type 2 (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202	PMID:38247817

Genomics

Comparative Map Data

MYO5B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	78,671,636 - 79,006,010 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	78,671,616 - 79,006,006 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	78,076,067 - 78,407,834 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	78,734,540 - 79,067,184 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	78,734,614 - 79,067,103 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	78,448,208 - 78,782,608 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	78,479,066 - 78,811,670 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	78,763,776 - 79,096,706 (+)	NCBI		UU_Cfam_GSD_1.0

MYO5B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	49,822,789 - 50,195,147 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	49,822,789 - 50,195,164 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	18	47,349,159 - 47,721,517 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	45,603,099 - 45,975,382 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	18	45,603,183 - 45,975,176	NCBI
Celera	18	44,205,823 - 44,578,011 (-)	NCBI		Celera
Cytogenetic Map	18	q21.1	NCBI
HuRef	18	44,203,440 - 44,575,850 (-)	NCBI		HuRef
CHM1_1	18	47,344,771 - 47,717,073 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	18	50,024,565 - 50,396,878 (-)	NCBI		T2T-CHM13v2.0

Myo5b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	74,575,435 - 74,905,769 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	74,574,007 - 74,904,564 (+)	Ensembl		GRCm39 Ensembl
GRCm38	18	74,442,364 - 74,772,698 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	74,440,936 - 74,771,493 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	74,602,273 - 74,931,131 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	74,567,984 - 74,896,170 (+)	NCBI		MGSCv36	mm8
Celera	18	75,677,935 - 75,995,786 (+)	NCBI		Celera
Cytogenetic Map	18	E2	NCBI
cM Map	18	50.7	NCBI

Myo5b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	70,313,717 - 70,613,918 (+)	NCBI		GRCr8
mRatBN7.2	18	68,038,759 - 68,341,568 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	68,038,759 - 68,338,745 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	70,146,914 - 70,446,818 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	70,812,463 - 71,116,126 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	68,671,318 - 68,972,854 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	70,426,865 - 70,729,985 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	70,427,007 - 70,729,030 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	69,568,169 - 69,869,070 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	71,381,068 - 71,580,824 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	71,454,267 - 71,654,025 (+)	NCBI
Celera	18	66,217,242 - 66,515,213 (+)	NCBI		Celera
Cytogenetic Map	18	q12.2	NCBI

Myo5b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	34,892,652 - 35,143,704 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955402	34,892,652 - 35,247,431 (-)	NCBI	ChiLan1.0	ChiLan1.0

MYO5B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	67,353,649 - 67,723,298 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	53,046,252 - 53,415,901 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	43,207,387 - 43,575,951 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	46,551,603 - 46,783,739 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	46,555,259 - 46,786,223 (-)	Ensembl	panpan1.1		panPan2

Myo5b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	37,781,039 - 37,998,722 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936497	12,932,789 - 13,234,244 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936497	12,932,367 - 13,236,916 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MYO5B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	99,418,449 - 99,810,139 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	99,418,242 - 99,810,934 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	109,021,575 - 109,119,992 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MYO5B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	30,759,345 - 31,143,139 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	30,759,764 - 31,143,474 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	4,906,479 - 5,290,645 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Myo5b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624778	13,347,705 - 13,740,767 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624778	13,352,285 - 13,740,621 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in MYO5B
5891 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_014115608	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038482506	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038543976	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038608074	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038672783	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000030178 ⟹ ENSCAFP00000028043

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	7	78,671,616 - 79,006,006 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000030181 ⟹ ENSCAFP00000028046

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	7	78,671,616 - 79,006,006 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000090271 ⟹ ENSCAFP00000047066

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	7	78,704,888 - 79,006,006 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845028249 ⟹ ENSCAFP00845022225

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	7	78,734,614 - 79,067,103 (+)	Ensembl

RefSeq Acc Id:

XM_014115608 ⟹ XP_013971083

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	7	78,671,636 - 79,006,010 (+)	NCBI
Dog10K_Boxer_Tasha	7	78,076,067 - 78,407,834 (+)	NCBI

Sequence:

show sequence

CGGGGAGCGCCCCCGCCCGCCAGTCCTGCCCGGCCGCCGCCGCGGGAGTAAAGGTCGCGCCGGC
CGGGAGCGAGCCGGCGGGGCAGGGCGTGGGGGAGGCGGCCACACGCCGGGAAAGTGTCGGCCGC
CCGGGAAGATGGCGCCAGGCGGGCTGGCCGCGGACTGAGCCTGCGGGCGGAGAGGAGTCGGGAC
CCGCAGCCCGGCAGGGGCGCGAGCGAGGGCCGCACGCAGACTCGCTGCCCGGGCTCGGGCCGGC
GCGCGGGGCCATGGCGGTGGGCGAGCTGTACAGCCAGTACACGAGGGTCTGGATCCCTGACCCT
GATGAAGTGTGGTGCTCGGCTGAATTAACCAAGGACTACAAGGAGGGAGAGAAGAGCCTCCAAC
TCAGACTGGAAGATGAATCGATTCGGGAATACCCCATCGATGTCCAAAGCAACCAGCTGCCTTT
TTTGCGGAATCCAGATATTTTGGTGGGAGAAAATGACCTAACTGCCCTTAGTTACCTACATGAG
CCTGCAGTTTTGCATAATTTAAAGGTCCGTTTCTTGGAGTCGAATCATATCTACACTTACTGTG
GTATCGTGCTCGTTGCCATTAATCCATATGAACAGTTGCCAATCTATGGTCAAGATGTCATCTA
TGCCTACAGTGGCCAAAACATGGGGGACATGGACCCCCACATCTTTGCTGTGGCAGAAGAAGCC
TACAAACAGATGGCCAGAGATGAGAAGAACCAGTCCATCATAGTCAGCGGGGAGTCTGGAGCTG
GCAAAACTGTGTCAGCCAAGTACGCCATGCGCTATTTTGCCACGGTTGGTGGCTCAGCCAGTGA
CACCAACATCGAAGAGAAGGTCCTGGCATCCAGTCCCATCATGGAGGCCATCGGAAATGCCAAA
ACCACGCGCAATGACAACAGCAGCCGATTTGGAAAGTACATTCAGATTGGCTTTGATAAGAGGT
ACCACATCATCGGGGCCAACATGAGGACCTACCTGCTGGAAAAATCCAGGGTGGTCTTTCAGGC
AGAAGATGAGCGCAATTACCACATCTTTTACCAGCTCTGTGCTGCAGCCAGTCTGCCGGAATTC
AAAGAGCTTATGCTAACATGTGCCGAGGACTTCTTCTACACCTCACAGGGAGGAGACATACGCA
TCGAGGGCATAGACGATGCTGAGGACTTTGAGAAGACACGACAAGCCTTCACGTTGCTGGGAGT
GAGAGAGTCCCATCAGATAAGCATTTTTAAGATAATTGCTTCTATCCTGCACCTTGGAAATGTG
GAGATTCAGGCTGAGCGTGATGGTGATTCCTGTAGTGTATCACCCCAGGATGAACACTTGAACA
GCTTCTGCCGCCTGCTGGGGGTGGAGCACAGTCAGATGGAGCACTGGCTCTGCCATCGCAAGCT
GGTCACCACCTCAGAGACCTATGTCAAGACTATGTCCCTGCAGCAGGTGGTCAATGCACGCAAC
GCCCTGGCCAAGCACATCTATGCCCAGCTGTTCAGCTGGATTGTAGAGCACATCAACAAGGCCC
TGTACACCCCTCTCAAGCAACACTCCTTCATCGGTGTCCTGGACATATACGGGTTTGAGACATT
TGAGGTCAACAGCTTTGAGCAGTTCTGTATCAACTATGCGAACGAGAAGCTGCAGCAGCAGTTC
AACTCGCATGTATTCAAACTAGAGCAAGAGGAATATATGAAGGAGGAGATCCCTTGGACCTTGA
TTGACTTTTATGATAACCAGCCCTGTATTGACCTCATAGAAGCAAAGCTAGGCATCTTGGACCT
GCTGGATGAAGAGTGTAAGGTCCCCAAGGGAACCGACCAAAACTGGGCCCAGAAGCTGTATGAC
CGGCACTCTGGCAGCCAGCACTTCCAGAAACCCCGCATGTCCAACACGGCCTTCATTGTCATCC
ACTTTGCCGATAAGGTGGAGTATCTTTCAGATGGTTTTCTGGAGAAAAACAGAGACACAGTATA
TGAAGAGCAGATCAACATCCTAAAGGCCAGCAAGTTCCCACTGGTGGCTGATCTGTTTCATGAT
GACAAGGACTCCGTTTCTGCCACCACTACATCTGGGAAGGGCTCGTCTTCCAAGATCAACATCC
GCTCTGCCAGACCTCCCCTGAAAGCTTCCAACAAGGAGCACAAGAGAACTGTGGGCCACCAGTT
CCGTACCTCCCTACACCTGCTCATGGAGACCCTAAATGCCACGACGCCGCACTACGTGCGCTGC
ATCAAGCCAAATGACGAGAAGCTCCCCTTCCACTTTGACCCCAAGAGAGCAGTGCAGCAGCTCC
GGGCATGTGGGGTGTTGGAGACAATCCGGATCAGTGCAGCCGGCTACCCATCCAGGTGGACTTA
CCACGACTTCTTCAACCGGTATCGGGTGCTGGTCAAGAAGAGAGAGCTTACCAGCACGGATAAA
AAGGCCATCTGCAGGTCTGTCCTAGAAAGCCTCATCAAGGATCCTGACAAGTTCCAGTTTGGCC
GCACCAAGATTTTCTTCCGGGCCGGCCAGGTGGCCTACCTAGAGAAGCTTCGGGCTGACAGGTT
CCGGGCCGCTACCATCATGATCCAGAAGACAGTCCGGGGCTGGCTTCAGAGGGTGAAGTACCGC
CGGCTGAAGATAGCGGCCTTAACGCTGCAGAGGTACTGCCGAGGACACCTGGCCCGCAGGCTGG
CTGAGCACCTGCGGAGGACACGGGCTGCCATCGTGCTCCAGAAGCAGTGCCGTATGTGGAGGGC
CCGCCAGGCCTACCAGAGGGTTTGTGGGGCCGCCGTTGTCATCCAGGCCTTCGCAAGGGGCATG
TTCGTGCGGAGGATCTACCAGCAGATCCTTTTGGAGCACAAGGCCACCATCCTGCAGAAGCACC
TGCGGGGCTGGATGGCACGCAGGCGCTTCCAGCGGCTCCGGGGTGCAGCCATCATCATCCAGTG
TGCCTTCCGGATGCTCAAGGCCAAGCAGGAGCTGAAGGCCCTCAAGATTGAGGCCCGCTCAGCG
GAGCACCTGAAGCGCCTCAATGTGGGCATGGAGAACAAGGTGGTCCAGCTGCAGCGGAAGATCG
ATGACCAGAACAAAGAGTTCAAGTCGCTGTCAGAGCAGTTGGCGGTGGCCACATCCACACACGC
CACGGAGGTGGAGAAGCTAAAGAAGGAGCTGGCCCAGTACCATCAGAGCCAGGGGGGCGGTGGC
CTGAGGCTGCAGGAGGAGGTCGAGAACCTGCGGGCTGAGCTCCAGAGGGCCCACTGTGAGCGCA
AGGTCCTGGAGGACACACACACCAGGGAGAAGGACGAGCTCAGAAAGCAAGTTGCAGTCCTGGA
GCAAGAAAATGCTCTCTTAAAAGATGAGAAAGAGCAGCTTAACAACCAAATCCTGTGCCAAGCG
AAAGATGAATTTGCCCAAAACTCTGTCAAGGAGAATCTCCTGATGAAGAAAGAGCTGGAGGAGG
AACGCTCCCGGTACCAGAACCTTGTGAAGGAATATTCGCGCTTGGAGCAGAGATACGACAACCT
TCGGGATGAGATGACCATCATCAAGCAAACCCCAGGCCACAGGCGGAACCCATCAAACCAAAGT
AGCTTGGAATCTGACTCCAACTACCCCTCCATCTCCACATCCGAGGTGGGAGACACAGAGGATG
CCCTCCAACAGGTGGAGGACGTTGGCCTGGAAAAGGCGGCCATGGACATGATGGTCTTCCTGAA
GCTGCAGAAGAGGGTGCGGGAGCTTGAGCAGGAGAGGAAGAAACTGCAGGTGCAGCTGGAGAAG
AGGGAGCAGCAGGACAGCAGGAGAGTCCAGGTGGAACAAGCAAAGAATGACCTAGATGTGGACC
AGGATGCAGATCTGGCCTACAATAGTCTGAAGAGGCAGGAGCTAGAGTCAGAGAACAAGAAGCT
GAAGAACGACCTGAACGAGTTGAGGAAAGCCGTGGCTGACCAAGCCACACAGGACAACTCCTCC
CACTGCTCCCCAGACGGCTATAGCCTGCTGCTGAACCAGCTCAAGCTGGCCAACGAGGAGCTTG
AGGTTCGCAAGGAGGAGGTGCTCATCCTGAGGACACAGATCGTCAGTGCTGACCAGCGCCGACT
CACTGGCAGGAGCACGGAGCCAAGCATTAATGCGAGAACAAGCTGGCCTAACAGTGAAAAGCAC
GTGGACCAGGAAGATGCCATTGAGGCTTATCATGGGGTCTGCCAGACAAACAGGTTGCTGGAGG
CGCAGCTGCAGGCACAGGGCCGCGAGCACAAGGCAGAGGTGGAGGCACTTCGGGCCCAGGTGGA
AGCCCTGAAGGAGGACCTGGACAGGCAGCAGCAGACCTTCTGCCAGACCCTGCTGCTGTCCCCG
GAGGCCCAGCTGGAGTTCGGGGTCCGCCAGGAGCTGACCCGGCTCACCAACGACAACCTGGACC
TCAAAGAACTGGTCGAAAAGCTGGAAAAGAATGAGAGGAAGCTTAAAAAACAGCTGAAGATTTA
CATGAAGAAAGTCCAGGACCTGGAAGCTGCCCAGGCACTGGCCCAGAGTGAGAGGAGGCGCCAT
GAGCTCAACAGACAGGTCACTGTCCAGCGGAAGGAGAAGGACTTCCAGGGCATGCTAGACTACC
ACAGGGAAGATGAGGCCCTTCTCATTCGGAACCTGGTGACAGACCTGAAGCCGCAGATGCTGAC
GGGCTCAGTGCCCTGCCTCCCTGCTTACATCCTCTATATGTGCATCCGGCACGCCGACTACATC
AACGACGACCTCAAGGTGCACTCCTTGCTGACCTCCACCATCAATGGCATTAAGAGAGTCCTGA
AGAAGCACAATGAGGACTTTGAGATGACCTCATTCTGGTTATCCAACACCTGCCGCCTCCTTCA
TTGCTTGAAGCAGTATAGTGGGGATGAGGGCTTCATGACTCAGAATACTGCCAAGCAGAATGAG
CACTGTCTTAAGAACTTTGACCTCACTGAATATCGTCAGGTGCTGAGTGACCTTTCCATTCAGA
TTTACCAGCAACTCATTAAGATCGCCGAGGGTGTTTTGCAACCTATGATAGTTTCCGCCATGCT
GGAAAATGAGAGCATTCAGGGTCTATCTGGTGTGAAGCCAACAGGATACCGGAAGCGCTCCTCC
AGCATGGTAGATGGGGACAACTCGTACTGCCTGGAAGCCATCATCCGCCAGATGAATTCCTTCC
ACACGGTCATGTGTGACCAGGGCCTGGACCCTGAGATCATCCTGCAGGTGTTCAAGCAGCTCTT
CTATATGATCAACGCCGTGACTCTCAACAACCTGCTCCTGCGGAAGGACGTCTGCTCTTGGAGC
ACAGGCATGCAGCTCAGGTACAATATAAGCCAACTGGAGGAGTGGCTTCGGGGAAGGAACCTTC
AGCAGAGCGGAGCTGTCCAGACTCTGGAGCCTCTGATCCAAGCAGCTCAACTCCTGCAGTTAAA
GAAGAAAACCCCAGAGGATGCGGAGGCCATCTGCTCCCTGTGCACCTCGCTCAGTACCCAGCAG
ATTGTCAAAATTTTAAACCTTTATACTCCAGTGAATGAATTTGAAGAACGGGTAACTGTGGCCT
TTATACGAACAATCCAGGCACAGCTCCAAGAGCGGAACGACCCTCAGCAGCTGCTGTTAGATTC
CAAACACATGTTTCCTGTTTTGTTTCCATTTAACCCGTCCTTGCTGACCATGGACTCAATCCAC
ATCCCAGCCTATCTCAATCTGGAGTTCCTCAATGAGGTCTGACAAGGTGCAGTCCCACCTGTGG
CTCCATTTCCAGTGAGAGCAAGAAGGAAGCGTACTATAAAGTGAATGTAAGAGTCTGTTAAATC
TGTAAAAGTGGATCAGATCCGAGACAGCCTGTGCAGAGTACTGAACTCTTCGGAGTAAGACATA
TCTGTCATTATTTTTTGTACCTACTGCTCAGAATAAAACACTTGAAATATGGAAGA

hide sequence

RefSeq Acc Id:

XM_038482506 ⟹ XP_038338434

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	7	78,448,208 - 78,782,608 (+)	NCBI

RefSeq Acc Id:

XM_038543976 ⟹ XP_038399904

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	7	78,763,776 - 79,096,706 (+)	NCBI

RefSeq Acc Id:

XM_038608074 ⟹ XP_038464002

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	7	78,479,066 - 78,811,670 (+)	NCBI

RefSeq Acc Id:

XM_038672783 ⟹ XP_038528711

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	7	78,734,540 - 79,067,184 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_013971083	(Get FASTA)	NCBI Sequence Viewer
	XP_038338434	(Get FASTA)	NCBI Sequence Viewer
	XP_038399904	(Get FASTA)	NCBI Sequence Viewer
	XP_038464002	(Get FASTA)	NCBI Sequence Viewer
	XP_038528711	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000028043.4
	ENSCAFP00000028046.5
	ENSCAFP00000047066.2
	ENSCAFP00000071122.1
	ENSCAFP00030003439.1
	ENSCAFP00030003540.1
	ENSCAFP00030003619.1
	ENSCAFP00030003735.1
	ENSCAFP00030003819.1
	ENSCAFP00040020494.1
	ENSCAFP00040020711.1
	ENSCAFP00040020957.1
	ENSCAFP00040021240.1
	ENSCAFP00845022225
	ENSCAFP00845022225.1

RefSeq Acc Id:

XP_013971083 ⟸ XM_014115608

- UniProtKB:

A0A8P0NK50 (UniProtKB/TrEMBL), A0A8C0LYT2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAVGELYSQYTRVWIPDPDEVWCSAELTKDYKEGEKSLQLRLEDESIREYPIDVQSNQLPFLRN
PDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYAYS
GQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASDTNI
EEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSRVVFQAEDE
RNYHIFYQLCAAASLPEFKELMLTCAEDFFYTSQGGDIRIEGIDDAEDFEKTRQAFTLLGVRES
HQISIFKIIASILHLGNVEIQAERDGDSCSVSPQDEHLNSFCRLLGVEHSQMEHWLCHRKLVTT
SETYVKTMSLQQVVNARNALAKHIYAQLFSWIVEHINKALYTPLKQHSFIGVLDIYGFETFEVN
SFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEEIPWTLIDFYDNQPCIDLIEAKLGILDLLDE
ECKVPKGTDQNWAQKLYDRHSGSQHFQKPRMSNTAFIVIHFADKVEYLSDGFLEKNRDTVYEEQ
INILKASKFPLVADLFHDDKDSVSATTTSGKGSSSKINIRSARPPLKASNKEHKRTVGHQFRTS
LHLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWTYHDF
FNRYRVLVKKRELTSTDKKAICRSVLESLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADRFRAA
TIMIQKTVRGWLQRVKYRRLKIAALTLQRYCRGHLARRLAEHLRRTRAAIVLQKQCRMWRARQA
YQRVCGAAVVIQAFARGMFVRRIYQQILLEHKATILQKHLRGWMARRRFQRLRGAAIIIQCAFR
MLKAKQELKALKIEARSAEHLKRLNVGMENKVVQLQRKIDDQNKEFKSLSEQLAVATSTHATEV
EKLKKELAQYHQSQGGGGLRLQEEVENLRAELQRAHCERKVLEDTHTREKDELRKQVAVLEQEN
ALLKDEKEQLNNQILCQAKDEFAQNSVKENLLMKKELEEERSRYQNLVKEYSRLEQRYDNLRDE
MTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEVGDTEDALQQVEDVGLEKAAMDMMVFLKLQK
RVRELEQERKKLQVQLEKREQQDSRRVQVEQAKNDLDVDQDADLAYNSLKRQELESENKKLKND
LNELRKAVADQATQDNSSHCSPDGYSLLLNQLKLANEELEVRKEEVLILRTQIVSADQRRLTGR
STEPSINARTSWPNSEKHVDQEDAIEAYHGVCQTNRLLEAQLQAQGREHKAEVEALRAQVEALK
EDLDRQQQTFCQTLLLSPEAQLEFGVRQELTRLTNDNLDLKELVEKLEKNERKLKKQLKIYMKK
VQDLEAAQALAQSERRRHELNRQVTVQRKEKDFQGMLDYHREDEALLIRNLVTDLKPQMLTGSV
PCLPAYILYMCIRHADYINDDLKVHSLLTSTINGIKRVLKKHNEDFEMTSFWLSNTCRLLHCLK
QYSGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQIYQQLIKIAEGVLQPMIVSAMLENE
SIQGLSGVKPTGYRKRSSSMVDGDNSYCLEAIIRQMNSFHTVMCDQGLDPEIILQVFKQLFYMI
NAVTLNNLLLRKDVCSWSTGMQLRYNISQLEEWLRGRNLQQSGAVQTLEPLIQAAQLLQLKKKT
PEDAEAICSLCTSLSTQQIVKILNLYTPVNEFEERVTVAFIRTIQAQLQERNDPQQLLLDSKHM
FPVLFPFNPSLLTMDSIHIPAYLNLEFLNEV

hide sequence

Ensembl Acc Id:

ENSCAFP00000028046 ⟸ ENSCAFT00000030181

Ensembl Acc Id:

ENSCAFP00000028043 ⟸ ENSCAFT00000030178

Ensembl Acc Id:

ENSCAFP00000047066 ⟸ ENSCAFT00000090271

RefSeq Acc Id:

XP_038338434 ⟸ XM_038482506

RefSeq Acc Id:

XP_038464002 ⟸ XM_038608074

RefSeq Acc Id:	XP_038528711 ⟸ XM_038672783
- UniProtKB:	A0A8I3NVA6 (UniProtKB/TrEMBL), A0A8C0LYT2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038399904 ⟸ XM_038543976
- UniProtKB:	A0A8C0LYT2 (UniProtKB/TrEMBL), A0A8I3NVA6 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845022225 ⟸ ENSCAFT00845028249

Protein Domains

Dilute Myosin motor Myosin N-terminal SH3-like

Promoters

RGD ID:

13684119

Promoter ID:

EPDNEW_C2187

Type:

single initiation site

Name:

MYO5B_1

Description:

myosin VB

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	7	78,671,867 - 78,671,927	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000018982	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030001960	UniProtKB/TrEMBL
	ENSCAFG00040012388	UniProtKB/TrEMBL
	ENSCAFG00845015859	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000030178.6	UniProtKB/TrEMBL
	ENSCAFT00000030181.5	UniProtKB/TrEMBL
	ENSCAFT00000090271.2	UniProtKB/TrEMBL
	ENSCAFT00000106185.1	UniProtKB/TrEMBL
	ENSCAFT00030003876.1	UniProtKB/TrEMBL
	ENSCAFT00030003989.1	UniProtKB/TrEMBL
	ENSCAFT00030004074.1	UniProtKB/TrEMBL
	ENSCAFT00030004207.1	UniProtKB/TrEMBL
	ENSCAFT00030004306.1	UniProtKB/TrEMBL
	ENSCAFT00040023607.1	UniProtKB/TrEMBL
	ENSCAFT00040023843.1	UniProtKB/TrEMBL
	ENSCAFT00040024125.1	UniProtKB/TrEMBL
	ENSCAFT00040024450.1	UniProtKB/TrEMBL
	ENSCAFT00845028249	ENTREZGENE
	ENSCAFT00845028249.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.820	UniProtKB/TrEMBL
	1.20.5.190	UniProtKB/TrEMBL
	1.20.58.530	UniProtKB/TrEMBL
	3.30.70.1590	UniProtKB/TrEMBL
	3.40.850.10	UniProtKB/TrEMBL
	6.20.240.20	UniProtKB/TrEMBL
	Myosin VI head, motor domain, U50 subdomain	UniProtKB/TrEMBL
InterPro	Dilute_dom	UniProtKB/TrEMBL
	IQ_motif_EF-hand-BS	UniProtKB/TrEMBL
	Kinesin_motor_dom_sf	UniProtKB/TrEMBL
	Myo5b_CBD	UniProtKB/TrEMBL
	Myosin_head_motor_dom	UniProtKB/TrEMBL
	Myosin_N	UniProtKB/TrEMBL
	MYSc_Myo5	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
NCBI Gene	MYO5B	ENTREZGENE
PANTHER	MYOSIN	UniProtKB/TrEMBL
	MYOSIN-11	UniProtKB/TrEMBL
	UNCONVENTIONAL MYOSIN-VB	UniProtKB/TrEMBL
	UNCONVENTIONAL MYOSIN-XIX	UniProtKB/TrEMBL
Pfam	DIL	UniProtKB/TrEMBL
	Myosin_head	UniProtKB/TrEMBL
	PF00612	UniProtKB/TrEMBL
PRINTS	MYOSINHEAVY	UniProtKB/TrEMBL
PROSITE	DILUTE	UniProtKB/TrEMBL
	MYOSIN_MOTOR	UniProtKB/TrEMBL
	PS50096	UniProtKB/TrEMBL
	SH3_LIKE	UniProtKB/TrEMBL
SMART	DIL	UniProtKB/TrEMBL
	MYSc	UniProtKB/TrEMBL
	SM00015	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A8C0LY60_CANLF	UniProtKB/TrEMBL
	A0A8C0LYT2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0LZ01_CANLF	UniProtKB/TrEMBL
	A0A8C0M3H5_CANLF	UniProtKB/TrEMBL
	A0A8C0RAT4_CANLF	UniProtKB/TrEMBL
	A0A8C0SFI1_CANLF	UniProtKB/TrEMBL
	A0A8C0SFX7_CANLF	UniProtKB/TrEMBL
	A0A8C0SFY1_CANLF	UniProtKB/TrEMBL
	A0A8C0SHR5_CANLF	UniProtKB/TrEMBL
	A0A8I3NVA6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0NK48_CANLF	UniProtKB/TrEMBL
	A0A8P0NK50	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0T007_CANLF	UniProtKB/TrEMBL
UniProt Secondary	A0A8P0PKY9	UniProtKB/TrEMBL
VGNC ID	VGNC:43569	ENTREZGENE

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InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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